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Items: 33


RhoGAPp190: A potential player in tbph-mediated neurodegeneration in Drosophila.

Langellotti S, Romano G, Feiguin F, Baralle FE, Romano M.

PLoS One. 2018 Apr 13;13(4):e0195845. doi: 10.1371/journal.pone.0195845. eCollection 2018.


Loss of ISWI Function in Drosophila Nuclear Bodies Drives Cytoplasmic Redistribution of Drosophila TDP-43.

Lo Piccolo L, Bonaccorso R, Attardi A, Li Greci L, Romano G, Sollazzo M, Giurato G, Ingrassia AMR, Feiguin F, Corona DFV, Onorati MC.

Int J Mol Sci. 2018 Apr 4;19(4). pii: E1082. doi: 10.3390/ijms19041082.


Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses.

Romano G, Holodkov N, Klima R, Grilli F, Guarnaccia C, Nizzardo M, Rizzo F, Garcia R, Feiguin F.

Sci Rep. 2018 Jan 29;8(1):1809. doi: 10.1038/s41598-018-19802-3.


Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells.

Appocher C, Mohagheghi F, Cappelli S, Stuani C, Romano M, Feiguin F, Buratti E.

Nucleic Acids Res. 2017 Jul 27;45(13):8026-8045. doi: 10.1093/nar/gkx477.


WDR79/TCAB1 plays a conserved role in the control of locomotion and ameliorates phenotypic defects in SMA models.

Di Giorgio ML, Esposito A, Maccallini P, Micheli E, Bavasso F, Gallotta I, Vernì F, Feiguin F, Cacchione S, McCabe BD, Di Schiavi E, Raffa GD.

Neurobiol Dis. 2017 Sep;105:42-50. doi: 10.1016/j.nbd.2017.05.005. Epub 2017 May 11.


A novel Drosophila model of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects.

Langellotti S, Romano V, Romano G, Klima R, Feiguin F, Cragnaz L, Romano M, Baralle FE.

Dis Model Mech. 2016 Jun 1;9(6):659-69. doi: 10.1242/dmm.023382. Epub 2016 Apr 21.


TBPH/TDP-43 modulates translation of Drosophila futsch mRNA through an UG-rich sequence within its 5'UTR.

Romano M, Feiguin F, Buratti E.

Brain Res. 2016 Sep 15;1647:50-56. doi: 10.1016/j.brainres.2016.02.022. Epub 2016 Feb 18.


An age-related reduction of brain TBPH/TDP-43 levels precedes the onset of locomotion defects in a Drosophila ALS model.

Cragnaz L, Klima R, De Conti L, Romano G, Feiguin F, Buratti E, Baralle M, Baralle FE.

Neuroscience. 2015 Dec 17;311:415-21. doi: 10.1016/j.neuroscience.2015.10.037. Epub 2015 Oct 27.


Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms.

Romano G, Appocher C, Scorzeto M, Klima R, Baralle FE, Megighian A, Feiguin F.

Hum Mol Genet. 2015 Nov 1;24(21):6134-45. doi: 10.1093/hmg/ddv330. Epub 2015 Aug 13.


Functional screening in Drosophila reveals the conserved role of REEP1 in promoting stress resistance and preventing the formation of Tau aggregates.

Appocher C, Klima R, Feiguin F.

Hum Mol Genet. 2014 Dec 20;23(25):6762-72. doi: 10.1093/hmg/ddu393. Epub 2014 Aug 5.


Chronological requirements of TDP-43 function in synaptic organization and locomotive control.

Romano G, Klima R, Buratti E, Verstreken P, Baralle FE, Feiguin F.

Neurobiol Dis. 2014 Nov;71:95-109. doi: 10.1016/j.nbd.2014.07.007. Epub 2014 Aug 1.


Aggregate formation prevents dTDP-43 neurotoxicity in the Drosophila melanogaster eye.

Cragnaz L, Klima R, Skoko N, Budini M, Feiguin F, Baralle FE.

Neurobiol Dis. 2014 Nov;71:74-80. doi: 10.1016/j.nbd.2014.07.009. Epub 2014 Jul 31.


HDAC6 is a Bruchpilot deacetylase that facilitates neurotransmitter release.

Miskiewicz K, Jose LE, Yeshaw WM, Valadas JS, Swerts J, Munck S, Feiguin F, Dermaut B, Verstreken P.

Cell Rep. 2014 Jul 10;8(1):94-102. doi: 10.1016/j.celrep.2014.05.051. Epub 2014 Jun 26.


Evolutionarily conserved heterogeneous nuclear ribonucleoprotein (hnRNP) A/B proteins functionally interact with human and Drosophila TAR DNA-binding protein 43 (TDP-43).

Romano M, Buratti E, Romano G, Klima R, Del Bel Belluz L, Stuani C, Baralle F, Feiguin F.

J Biol Chem. 2014 Mar 7;289(10):7121-30. doi: 10.1074/jbc.M114.548859. Epub 2014 Feb 3.


Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model.

Llamusi B, Bargiela A, Fernandez-Costa JM, Garcia-Lopez A, Klima R, Feiguin F, Artero R.

Dis Model Mech. 2013 Jan;6(1):184-96. doi: 10.1242/dmm.009563. Epub 2012 Nov 1.


Drosophila Answers to TDP-43 Proteinopathies.

Romano M, Feiguin F, Buratti E.

J Amino Acids. 2012;2012:356081. doi: 10.1155/2012/356081. Epub 2012 Apr 18.


Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-β production by altering Nicastrin maturation and intracellular localization.

Michaki V, Guix FX, Vennekens K, Munck S, Dingwall C, Davis JB, Townsend DM, Tew KD, Feiguin F, De Strooper B, Dotti CG, Wahle T.

J Biol Chem. 2012 Jan 6;287(2):1100-11. doi: 10.1074/jbc.M111.288258. Epub 2011 Nov 15.


Alterations in phosphatidylethanolamine levels affect the generation of Aβ.

Nesic I, Guix FX, Vennekens K, Michaki V, Van Veldhoven PP, Feiguin F, De Strooper B, Dotti CG, Wahle T.

Aging Cell. 2012 Feb;11(1):63-72. doi: 10.1111/j.1474-9726.2011.00760.x. Epub 2011 Nov 28.


TDP-43 regulates Drosophila neuromuscular junctions growth by modulating Futsch/MAP1B levels and synaptic microtubules organization.

Godena VK, Romano G, Romano M, Appocher C, Klima R, Buratti E, Baralle FE, Feiguin F.

PLoS One. 2011 Mar 11;6(3):e17808. doi: 10.1371/journal.pone.0017808.


Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior.

Feiguin F, Godena VK, Romano G, D'Ambrogio A, Klima R, Baralle FE.

FEBS Lett. 2009 May 19;583(10):1586-92. doi: 10.1016/j.febslet.2009.04.019. Epub 2009 Apr 19.


Dissecting the splicing mechanism of the Drosophila editing enzyme; dADAR.

Marcucci R, Romano M, Feiguin F, O'Connell MA, Baralle FE.

Nucleic Acids Res. 2009 Apr;37(5):1663-71. doi: 10.1093/nar/gkn1080. Epub 2009 Jan 19.


gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo.

Doglio LE, Kanwar R, Jackson GR, Perez M, Avila J, Dingwall C, Dotti CG, Fortini ME, Feiguin F.

Neuron. 2006 May 4;50(3):359-75. Retraction in: Dotti CG, Feiguin F, Fortini ME. Neuron. 2007 Feb 1;53(3):463.


Self-refinement of Notch activity through the transmembrane protein Crumbs: modulation of gamma-secretase activity.

Herranz H, Stamataki E, Feiguin F, Milán M.

EMBO Rep. 2006 Mar;7(3):297-302. Epub 2006 Jan 20.


Centrosome localization determines neuronal polarity.

de Anda FC, Pollarolo G, Da Silva JS, Camoletto PG, Feiguin F, Dotti CG.

Nature. 2005 Aug 4;436(7051):704-8.


Planar cell polarization requires Widerborst, a B' regulatory subunit of protein phosphatase 2A.

Hannus M, Feiguin F, Heisenberg CP, Eaton S.

Development. 2002 Jul;129(14):3493-503.


The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization.

Feiguin F, Hannus M, Mlodzik M, Eaton S.

Dev Cell. 2001 Jul;1(1):93-101.


The Drosophila STE20-like kinase misshapen is required downstream of the Frizzled receptor in planar polarity signaling.

Paricio N, Feiguin F, Boutros M, Eaton S, Mlodzik M.

EMBO J. 1999 Sep 1;18(17):4669-78.


Methods in Drosophila cell cycle biology.

Feiguin F, Llamazares S, González C.

Curr Top Dev Biol. 1998;36:279-91. Review. No abstract available.


MAP-1B/TAU functional redundancy during laminin-enhanced axonal growth.

DiTella MC, Feiguin F, Carri N, Kosik KS, Cáceres A.

J Cell Sci. 1996 Feb;109 ( Pt 2):467-77.


Kinesin-mediated organelle translocation revealed by specific cellular manipulations.

Feiguin F, Ferreira A, Kosik KS, Caceres A.

J Cell Biol. 1994 Nov;127(4):1021-39.


Neurotrophin-3 enhances neurite outgrowth in cultured hippocampal pyramidal neurons.

Morfini G, DiTella MC, Feiguin F, Carri N, Cáceres A.

J Neurosci Res. 1994 Oct 1;39(2):219-32.


Microfilament-associated growth cone component depends upon Tau for its intracellular localization.

DiTella M, Feiguin F, Morfini G, Cáceres A.

Cell Motil Cytoskeleton. 1994;29(2):117-30.


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