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Items: 41

1.

Sex-Specific Associations of Blood-Based Nutrient Profiling With Body Composition in the Elderly.

Konz T, Santoro A, Goulet L, Bazzocchi A, Battista G, Nicoletti C, Kadi F, Ostan R, Goy M, Monnard C, Martin FP, Feige JN, Franceschi C, Rezzi S.

Front Physiol. 2019 Jan 24;9:1935. doi: 10.3389/fphys.2018.01935. eCollection 2018.

2.

Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors.

Lukjanenko L, Karaz S, Stuelsatz P, Gurriaran-Rodriguez U, Michaud J, Dammone G, Sizzano F, Mashinchian O, Ancel S, Migliavacca E, Liot S, Jacot G, Metairon S, Raymond F, Descombes P, Palini A, Chazaud B, Rudnicki MA, Bentzinger CF, Feige JN.

Cell Stem Cell. 2019 Mar 7;24(3):433-446.e7. doi: 10.1016/j.stem.2018.12.014. Epub 2019 Jan 24.

PMID:
30686765
3.

The exerkine apelin reverses age-associated sarcopenia.

Vinel C, Lukjanenko L, Batut A, Deleruyelle S, Pradère JP, Le Gonidec S, Dortignac A, Geoffre N, Pereira O, Karaz S, Lee U, Camus M, Chaoui K, Mouisel E, Bigot A, Mouly V, Vigneau M, Pagano AF, Chopard A, Pillard F, Guyonnet S, Cesari M, Burlet-Schiltz O, Pahor M, Feige JN, Vellas B, Valet P, Dray C.

Nat Med. 2018 Sep;24(9):1360-1371. doi: 10.1038/s41591-018-0131-6. Epub 2018 Jul 30.

PMID:
30061698
4.

PPARγ Controls Ectopic Adipogenesis and Cross-Talks with Myogenesis During Skeletal Muscle Regeneration.

Dammone G, Karaz S, Lukjanenko L, Winkler C, Sizzano F, Jacot G, Migliavacca E, Palini A, Desvergne B, Gilardi F, Feige JN.

Int J Mol Sci. 2018 Jul 13;19(7). pii: E2044. doi: 10.3390/ijms19072044.

5.

Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle.

Perrin L, Loizides-Mangold U, Chanon S, Gobet C, Hulo N, Isenegger L, Weger BD, Migliavacca E, Charpagne A, Betts JA, Walhin JP, Templeman I, Stokes K, Thompson D, Tsintzas K, Robert M, Howald C, Riezman H, Feige JN, Karagounis LG, Johnston JD, Dermitzakis ET, Gachon F, Lefai E, Dibner C.

Elife. 2018 Apr 16;7. pii: e34114. doi: 10.7554/eLife.34114.

6.

Vitamin B12 deficiency and impaired expression of amnionless during aging.

Pannérec A, Migliavacca E, De Castro A, Michaud J, Karaz S, Goulet L, Rezzi S, Ng TP, Bosco N, Larbi A, Feige JN.

J Cachexia Sarcopenia Muscle. 2018 Feb;9(1):41-52. doi: 10.1002/jcsm.12260. Epub 2017 Nov 21.

7.

Aging and sarcopenia associate with specific interactions between gut microbes, serum biomarkers and host physiology in rats.

Siddharth J, Chakrabarti A, Pannérec A, Karaz S, Morin-Rivron D, Masoodi M, Feige JN, Parkinson SJ.

Aging (Albany NY). 2017 Jul 17;9(7):1698-1720. doi: 10.18632/aging.101262.

8.

Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice.

Lukjanenko L, Jung MJ, Hegde N, Perruisseau-Carrier C, Migliavacca E, Rozo M, Karaz S, Jacot G, Schmidt M, Li L, Metairon S, Raymond F, Lee U, Sizzano F, Wilson DH, Dumont NA, Palini A, Fässler R, Steiner P, Descombes P, Rudnicki MA, Fan CM, von Maltzahn J, Feige JN, Bentzinger CF.

Nat Med. 2016 Aug;22(8):897-905. doi: 10.1038/nm.4126. Epub 2016 Jul 4.

9.

A robust neuromuscular system protects rat and human skeletal muscle from sarcopenia.

Pannérec A, Springer M, Migliavacca E, Ireland A, Piasecki M, Karaz S, Jacot G, Métairon S, Danenberg E, Raymond F, Descombes P, McPhee JS, Feige JN.

Aging (Albany NY). 2016 Apr;8(4):712-29. doi: 10.18632/aging.100926.

10.

An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy.

Lach-Trifilieff E, Minetti GC, Sheppard K, Ibebunjo C, Feige JN, Hartmann S, Brachat S, Rivet H, Koelbing C, Morvan F, Hatakeyama S, Glass DJ.

Mol Cell Biol. 2014 Feb;34(4):606-18. doi: 10.1128/MCB.01307-13. Epub 2013 Dec 2.

11.

Gαi2 signaling is required for skeletal muscle growth, regeneration, and satellite cell proliferation and differentiation.

Minetti GC, Feige JN, Bombard F, Heier A, Morvan F, Nürnberg B, Leiss V, Birnbaumer L, Glass DJ, Fornaro M.

Mol Cell Biol. 2014 Feb;34(4):619-30. doi: 10.1128/MCB.00957-13. Epub 2013 Dec 2.

12.

Genomic profiling reveals that transient adipogenic activation is a hallmark of mouse models of skeletal muscle regeneration.

Lukjanenko L, Brachat S, Pierrel E, Lach-Trifilieff E, Feige JN.

PLoS One. 2013 Aug 15;8(8):e71084. doi: 10.1371/journal.pone.0071084. eCollection 2013.

13.

The corepressor NCoR1 antagonizes PGC-1α and estrogen-related receptor α in the regulation of skeletal muscle function and oxidative metabolism.

Pérez-Schindler J, Summermatter S, Salatino S, Zorzato F, Beer M, Balwierz PJ, van Nimwegen E, Feige JN, Auwerx J, Handschin C.

Mol Cell Biol. 2012 Dec;32(24):4913-24. doi: 10.1128/MCB.00877-12. Epub 2012 Oct 1.

14.

Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism.

Fournier B, Murray B, Gutzwiller S, Marcaletti S, Marcellin D, Bergling S, Brachat S, Persohn E, Pierrel E, Bombard F, Hatakeyama S, Trendelenburg AU, Morvan F, Richardson B, Glass DJ, Lach-Trifilieff E, Feige JN.

Mol Cell Biol. 2012 Jul;32(14):2871-9. doi: 10.1128/MCB.06575-11. Epub 2012 May 14.

15.

TAK-1/p38/nNFκB signaling inhibits myoblast differentiation by increasing levels of Activin A.

Trendelenburg AU, Meyer A, Jacobi C, Feige JN, Glass DJ.

Skelet Muscle. 2012 Feb 7;2(1):3. doi: 10.1186/2044-5040-2-3.

16.

Gαi2 signaling promotes skeletal muscle hypertrophy, myoblast differentiation, and muscle regeneration.

Minetti GC, Feige JN, Rosenstiel A, Bombard F, Meier V, Werner A, Bassilana F, Sailer AW, Kahle P, Lambert C, Glass DJ, Fornaro M.

Sci Signal. 2011 Nov 29;4(201):ra80. doi: 10.1126/scisignal.2002038.

17.

CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability.

Noriega LG, Feige JN, Canto C, Yamamoto H, Yu J, Herman MA, Mataki C, Kahn BB, Auwerx J.

EMBO Rep. 2011 Sep 30;12(10):1069-76. doi: 10.1038/embor.2011.151.

18.

Assessment of Spontaneous Locomotor and Running Activity in Mice.

Thomas C, Marcaletti S, Feige JN.

Curr Protoc Mouse Biol. 2011 Mar 1;1(1):185-98. doi: 10.1002/9780470942390.mo100170.

PMID:
26068992
19.

Exercise Performance Tests in Mice.

Marcaletti S, Thomas C, Feige JN.

Curr Protoc Mouse Biol. 2011 Mar 1;1(1):141-54. doi: 10.1002/9780470942390.mo100160.

PMID:
26068989
20.

The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific PPARalpha-dependent mechanisms.

Feige JN, Gerber A, Casals-Casas C, Yang Q, Winkler C, Bedu E, Bueno M, Gelman L, Auwerx J, Gonzalez FJ, Desvergne B.

Environ Health Perspect. 2010 Feb;118(2):234-41. doi: 10.1289/ehp.0901217.

21.

PPAR-mediated activity of phthalates: A link to the obesity epidemic?

Desvergne B, Feige JN, Casals-Casas C.

Mol Cell Endocrinol. 2009 May 25;304(1-2):43-8. doi: 10.1016/j.mce.2009.02.017. Epub 2009 Mar 9. Review.

PMID:
19433246
22.

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity.

Cantó C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, Milne JC, Elliott PJ, Puigserver P, Auwerx J.

Nature. 2009 Apr 23;458(7241):1056-60. doi: 10.1038/nature07813.

23.

The Pro12Ala PPARgamma2 variant determines metabolism at the gene-environment interface.

Heikkinen S, Argmann C, Feige JN, Koutnikova H, Champy MF, Dali-Youcef N, Schadt EE, Laakso M, Auwerx J.

Cell Metab. 2009 Jan 7;9(1):88-98. doi: 10.1016/j.cmet.2008.11.007.

24.

Interference of pollutants with PPARs: endocrine disruption meets metabolism.

Casals-Casas C, Feige JN, Desvergne B.

Int J Obes (Lond). 2008 Dec;32 Suppl 6:S53-61. doi: 10.1038/ijo.2008.207. Review.

PMID:
19079281
25.

Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration.

Polak P, Cybulski N, Feige JN, Auwerx J, Rüegg MA, Hall MN.

Cell Metab. 2008 Nov;8(5):399-410. doi: 10.1016/j.cmet.2008.09.003.

26.

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation.

Feige JN, Lagouge M, Canto C, Strehle A, Houten SM, Milne JC, Lambert PD, Mataki C, Elliott PJ, Auwerx J.

Cell Metab. 2008 Nov;8(5):347-58. doi: 10.1016/j.cmet.2008.08.017. Erratum in: Cell Metab. 2009 Feb;9(2):210.

27.

Dietary manipulation of mouse metabolism.

Feige JN, Lagouge M, Auwerx J.

Curr Protoc Mol Biol. 2008 Oct;Chapter 29:Unit 29B.5. doi: 10.1002/0471142727.mb29b05s84.

PMID:
18972384
28.

Transcriptional targets of sirtuins in the coordination of mammalian physiology.

Feige JN, Auwerx J.

Curr Opin Cell Biol. 2008 Jun;20(3):303-9. doi: 10.1016/j.ceb.2008.03.012. Epub 2008 May 28. Review.

29.

DisSIRTing on LXR and cholesterol metabolism.

Feige JN, Auwerx J.

Cell Metab. 2007 Nov;6(5):343-5.

30.

Transcriptional coregulators in the control of energy homeostasis.

Feige JN, Auwerx J.

Trends Cell Biol. 2007 Jun;17(6):292-301. Epub 2007 May 1. Review.

PMID:
17475497
31.

The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesis.

Feige JN, Gelman L, Rossi D, Zoete V, Métivier R, Tudor C, Anghel SI, Grosdidier A, Lathion C, Engelborghs Y, Michielin O, Wahli W, Desvergne B.

J Biol Chem. 2007 Jun 29;282(26):19152-66. Epub 2007 Apr 27.

32.

Molecular basis of selective PPARgamma modulation for the treatment of Type 2 diabetes.

Gelman L, Feige JN, Desvergne B.

Biochim Biophys Acta. 2007 Aug;1771(8):1094-107. Epub 2007 Mar 16. Review.

PMID:
17459763
33.

Combined simulation and mutagenesis analyses reveal the involvement of key residues for peroxisome proliferator-activated receptor alpha helix 12 dynamic behavior.

Michalik L, Zoete V, Krey G, Grosdidier A, Gelman L, Chodanowski P, Feige JN, Desvergne B, Wahli W, Michielin O.

J Biol Chem. 2007 Mar 30;282(13):9666-77. Epub 2007 Jan 2.

34.

Association with coregulators is the major determinant governing peroxisome proliferator-activated receptor mobility in living cells.

Tudor C, Feige JN, Pingali H, Lohray VB, Wahli W, Desvergne B, Engelborghs Y, Gelman L.

J Biol Chem. 2007 Feb 16;282(7):4417-26. Epub 2006 Dec 12.

35.

Integrating nuclear receptor mobility in models of gene regulation.

Gelman L, Feige JN, Tudor C, Engelborghs Y, Wahli W, Desvergne B.

Nucl Recept Signal. 2006;4:e010. Epub 2006 Apr 28.

36.

From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions.

Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W.

Prog Lipid Res. 2006 Mar;45(2):120-59. Epub 2006 Jan 25. Review.

PMID:
16476485
37.

Scaffold attachment factor B1 directly interacts with nuclear receptors in living cells and represses transcriptional activity.

Debril MB, Dubuquoy L, Feige JN, Wahli W, Desvergne B, Auwerx J, Gelman L.

J Mol Endocrinol. 2005 Dec;35(3):503-17.

PMID:
16326836
38.

PixFRET, an ImageJ plug-in for FRET calculation that can accommodate variations in spectral bleed-throughs.

Feige JN, Sage D, Wahli W, Desvergne B, Gelman L.

Microsc Res Tech. 2005 Sep;68(1):51-8.

PMID:
16208719
39.

Selective expression of a dominant-negative form of peroxisome proliferator-activated receptor in keratinocytes leads to impaired epidermal healing.

Michalik L, Feige JN, Gelman L, Pedrazzini T, Keller H, Desvergne B, Wahli W.

Mol Endocrinol. 2005 Sep;19(9):2335-48. Epub 2005 May 12.

PMID:
15890673
40.

Fluorescence imaging reveals the nuclear behavior of peroxisome proliferator-activated receptor/retinoid X receptor heterodimers in the absence and presence of ligand.

Feige JN, Gelman L, Tudor C, Engelborghs Y, Wahli W, Desvergne B.

J Biol Chem. 2005 May 6;280(18):17880-90. Epub 2005 Feb 24.

41.

A transporter of Escherichia coli specific for L- and D-methionine is the prototype for a new family within the ABC superfamily.

Zhang Z, Feige JN, Chang AB, Anderson IJ, Brodianski VM, Vitreschak AG, Gelfand MS, Saier MH Jr.

Arch Microbiol. 2003 Aug;180(2):88-100. Epub 2003 Jun 19.

PMID:
12819857

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