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Items: 39


Clustered CTCF binding is an evolutionary mechanism to maintain topologically associating domains.

Kentepozidou E, Aitken SJ, Feig C, Stefflova K, Ibarra-Soria X, Odom DT, Roller M, Flicek P.

Genome Biol. 2020 Jan 7;21(1):5. doi: 10.1186/s13059-019-1894-x.


A perspective on nonadherence to drug therapy: psychological barriers and strategies to overcome nonadherence.

Martin LR, Feig C, Maksoudian CR, Wysong K, Faasse K.

Patient Prefer Adherence. 2018 Aug 22;12:1527-1535. doi: 10.2147/PPA.S155971. eCollection 2018. Review.


CTCF maintains regulatory homeostasis of cancer pathways.

Aitken SJ, Ibarra-Soria X, Kentepozidou E, Flicek P, Feig C, Marioni JC, Odom DT.

Genome Biol. 2018 Aug 7;19(1):106. doi: 10.1186/s13059-018-1484-3.


Mutational landscape of a chemically-induced mouse model of liver cancer.

Connor F, Rayner TF, Aitken SJ, Feig C, Lukk M, Santoyo-Lopez J, Odom DT.

J Hepatol. 2018 Oct;69(4):840-850. doi: 10.1016/j.jhep.2018.06.009. Epub 2018 Jun 26.


Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes.

Thybert D, Roller M, Navarro FCP, Fiddes I, Streeter I, Feig C, Martin-Galvez D, Kolmogorov M, Janoušek V, Akanni W, Aken B, Aldridge S, Chakrapani V, Chow W, Clarke L, Cummins C, Doran A, Dunn M, Goodstadt L, Howe K, Howell M, Josselin AA, Karn RC, Laukaitis CM, Jingtao L, Martin F, Muffato M, Nachtweide S, Quail MA, Sisu C, Stanke M, Stefflova K, Van Oosterhout C, Veyrunes F, Ward B, Yang F, Yazdanifar G, Zadissa A, Adams DJ, Brazma A, Gerstein M, Paten B, Pham S, Keane TM, Odom DT, Flicek P.

Genome Res. 2018 Apr;28(4):448-459. doi: 10.1101/gr.234096.117. Epub 2018 Mar 21.


Interplay of cis and trans mechanisms driving transcription factor binding and gene expression evolution.

Wong ES, Schmitt BM, Kazachenka A, Thybert D, Redmond A, Connor F, Rayner TF, Feig C, Ferguson-Smith AC, Marioni JC, Odom DT, Flicek P.

Nat Commun. 2017 Oct 23;8(1):1092. doi: 10.1038/s41467-017-01037-x.


Best-worst scaling to assess the most important barriers and facilitators for the use of health technology assessment in Austria.

Feig C, Cheung KL, Hiligsmann M, Evers SMAA, Simon J, Mayer S.

Expert Rev Pharmacoecon Outcomes Res. 2018 Apr;18(2):223-232. doi: 10.1080/14737167.2017.1375407. Epub 2017 Sep 8.


Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.

Öhlund D, Handly-Santana A, Biffi G, Elyada E, Almeida AS, Ponz-Sarvise M, Corbo V, Oni TE, Hearn SA, Lee EJ, Chio II, Hwang CI, Tiriac H, Baker LA, Engle DD, Feig C, Kultti A, Egeblad M, Fearon DT, Crawford JM, Clevers H, Park Y, Tuveson DA.

J Exp Med. 2017 Mar 6;214(3):579-596. doi: 10.1084/jem.20162024. Epub 2017 Feb 23.


Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma.

Carapuça EF, Gemenetzidis E, Feig C, Bapiro TE, Williams MD, Wilson AS, Delvecchio FR, Arumugam P, Grose RP, Lemoine NR, Richards FM, Kocher HM.

J Pathol. 2016 Jul;239(3):286-96. doi: 10.1002/path.4727. Epub 2016 May 25.


Set of interviews.

Navarro D, Aylward B, Fukuda K, Heymann D, Rodier G, Feig C, Kindhauser MK, Niang CI.

Wkly Epidemiol Rec. 2015 May 15;90(20):218-35. English, French. No abstract available.


Soft, Brown Rupture: Clinical Signs and Symptoms Associated with Ruptured PIP Breast Implants.

Godwin Y, Duncan RT, Feig C, Reintals M, Hill S.

Plast Reconstr Surg Glob Open. 2014 Dec 5;2(11):e249. doi: 10.1097/GOX.0000000000000212. eCollection 2014 Nov.


WHO disapproves Kochon prize for Tibetan TB Programme - WHO's reply.

Feig C.

Lancet. 2014 Mar 8;383(9920):868-9. doi: 10.1016/S0140-6736(14)60442-6. No abstract available.


Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.

Feig C, Jones JO, Kraman M, Wells RJ, Deonarine A, Chan DS, Connell CM, Roberts EW, Zhao Q, Caballero OL, Teichmann SA, Janowitz T, Jodrell DI, Tuveson DA, Fearon DT.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20212-7. doi: 10.1073/pnas.1320318110. Epub 2013 Nov 25.


Cohesin's role as an active chromatin domain anchorage revealed.

Feig C, Odom DT.

EMBO J. 2013 Dec 11;32(24):3114-5. doi: 10.1038/emboj.2013.248. Epub 2013 Nov 22.


Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia.

Roberts EW, Deonarine A, Jones JO, Denton AE, Feig C, Lyons SK, Espeli M, Kraman M, McKenna B, Wells RJ, Zhao Q, Caballero OL, Larder R, Coll AP, O'Rahilly S, Brindle KM, Teichmann SA, Tuveson DA, Fearon DT.

J Exp Med. 2013 Jun 3;210(6):1137-51. doi: 10.1084/jem.20122344. Epub 2013 May 27.


Fold-change correction values for testicular somatic transcripts in gene expression studies of human spermatogenesis.

Cappallo-Obermann H, Feig C, Schulze W, Spiess AN.

Hum Reprod. 2013 Mar;28(3):590-8. doi: 10.1093/humrep/des433. Epub 2013 Jan 9.


Global human tissue profiling and protein network analysis reveals distinct levels of transcriptional germline-specificity and identifies target genes for male infertility.

Chalmel F, Lardenois A, Evrard B, Mathieu R, Feig C, Demougin P, Gattiker A, Schulze W, Jégou B, Kirchhoff C, Primig M.

Hum Reprod. 2012 Nov;27(11):3233-48. doi: 10.1093/humrep/des301. Epub 2012 Aug 27.


The pancreas cancer microenvironment.

Feig C, Gopinathan A, Neesse A, Chan DS, Cook N, Tuveson DA.

Clin Cancer Res. 2012 Aug 15;18(16):4266-76. doi: 10.1158/1078-0432.CCR-11-3114. Review.


Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.

Jacobetz MA, Chan DS, Neesse A, Bapiro TE, Cook N, Frese KK, Feig C, Nakagawa T, Caldwell ME, Zecchini HI, Lolkema MP, Jiang P, Kultti A, Thompson CB, Maneval DC, Jodrell DI, Frost GI, Shepard HM, Skepper JN, Tuveson DA.

Gut. 2013 Jan;62(1):112-20. doi: 10.1136/gutjnl-2012-302529. Epub 2012 Mar 30.


Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression.

Froeling FE, Feig C, Chelala C, Dobson R, Mein CE, Tuveson DA, Clevers H, Hart IR, Kocher HM.

Gastroenterology. 2011 Oct;141(4):1486-97, 1497.e1-14. doi: 10.1053/j.gastro.2011.06.047. Epub 2011 Jun 24.


Stromal biology and therapy in pancreatic cancer.

Neesse A, Michl P, Frese KK, Feig C, Cook N, Jacobetz MA, Lolkema MP, Buchholz M, Olive KP, Gress TM, Tuveson DA.

Gut. 2011 Jun;60(6):861-8. doi: 10.1136/gut.2010.226092. Epub 2010 Oct 21. Review.


CD95 promotes tumour growth.

Chen L, Park SM, Tumanov AV, Hau A, Sawada K, Feig C, Turner JR, Fu YX, Romero IL, Lengyel E, Peter ME.

Nature. 2010 May 27;465(7297):492-6. doi: 10.1038/nature09075. Erratum in: Nature. 2011 Jul 14;475(7355):254. Nature. 2011 Mar 10;471(7337):254. Nature. 2012 Nov 29;491(7426):784.


Screening for biomarkers of spermatogonia within the human testis: a whole genome approach.

von Kopylow K, Kirchhoff C, Jezek D, Schulze W, Feig C, Primig M, Steinkraus V, Spiess AN.

Hum Reprod. 2010 May;25(5):1104-12. doi: 10.1093/humrep/deq053. Epub 2010 Mar 5.


Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.

Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, Honess D, Madhu B, Goldgraben MA, Caldwell ME, Allard D, Frese KK, Denicola G, Feig C, Combs C, Winter SP, Ireland-Zecchini H, Reichelt S, Howat WJ, Chang A, Dhara M, Wang L, Rückert F, Grützmann R, Pilarsky C, Izeradjene K, Hingorani SR, Huang P, Davies SE, Plunkett W, Egorin M, Hruban RH, Whitebread N, McGovern K, Adams J, Iacobuzio-Donahue C, Griffiths J, Tuveson DA.

Science. 2009 Jun 12;324(5933):1457-61. doi: 10.1126/science.1171362. Epub 2009 May 21.


Methods to analyze the palmitoylated CD95 high molecular weight death-inducing signaling complex.

Feig C, Peter ME.

Methods Enzymol. 2008;442:83-100. doi: 10.1016/S0076-6879(08)01404-3.


Highly accurate sigmoidal fitting of real-time PCR data by introducing a parameter for asymmetry.

Spiess AN, Feig C, Ritz C.

BMC Bioinformatics. 2008 Apr 29;9:221. doi: 10.1186/1471-2105-9-221.


Identification of let-7-regulated oncofetal genes.

Boyerinas B, Park SM, Shomron N, Hedegaard MM, Vinther J, Andersen JS, Feig C, Xu J, Burge CB, Peter ME.

Cancer Res. 2008 Apr 15;68(8):2587-91. doi: 10.1158/0008-5472.CAN-08-0264.


How apoptosis got the immune system in shape.

Feig C, Peter ME.

Eur J Immunol. 2007 Nov;37 Suppl 1:S61-70. Review.


Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2.

Park SM, Shell S, Radjabi AR, Schickel R, Feig C, Boyerinas B, Dinulescu DM, Lengyel E, Peter ME.

Cell Cycle. 2007 Nov 1;6(21):2585-90. Epub 2007 Aug 6.


Cross-platform gene expression signature of human spermatogenic failure reveals inflammatory-like response.

Spiess AN, Feig C, Schulze W, Chalmel F, Cappallo-Obermann H, Primig M, Kirchhoff C.

Hum Reprod. 2007 Nov;22(11):2936-46. Epub 2007 Oct 6.


Let-7 expression defines two differentiation stages of cancer.

Shell S, Park SM, Radjabi AR, Schickel R, Kistner EO, Jewell DA, Feig C, Lengyel E, Peter ME.

Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11400-5. Epub 2007 Jun 28.


Immortalized Sertoli cell lines sk11 and sk9 and binding of spermatids in vitro.

Wolski KM, Feig C, Kirchhoff C, Cameron DF.

Asian J Androl. 2007 May;9(3):312-20.


Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling.

Feig C, Tchikov V, Schütze S, Peter ME.

EMBO J. 2007 Jan 10;26(1):221-31. Epub 2006 Dec 7.


A new paradigm for profiling testicular gene expression during normal and disturbed human spermatogenesis.

Feig C, Kirchhoff C, Ivell R, Naether O, Schulze W, Spiess AN.

Mol Hum Reprod. 2007 Jan;13(1):33-43. Epub 2006 Nov 17.


The role of receptor internalization in CD95 signaling.

Lee KH, Feig C, Tchikov V, Schickel R, Hallas C, Schütze S, Peter ME, Chan AC.

EMBO J. 2006 Mar 8;25(5):1009-23. Epub 2006 Feb 23.


Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities.

Alappat EC, Feig C, Boyerinas B, Volkland J, Samuels M, Murmann AE, Thorburn A, Kidd VJ, Slaughter CA, Osborn SL, Winoto A, Tang WJ, Peter ME.

Mol Cell. 2005 Aug 5;19(3):321-32.


egc-Encoded superantigens from Staphylococcus aureus are neutralized by human sera much less efficiently than are classical staphylococcal enterotoxins or toxic shock syndrome toxin.

Holtfreter S, Bauer K, Thomas D, Feig C, Lorenz V, Roschack K, Friebe E, Selleng K, Lövenich S, Greve T, Greinacher A, Panzig B, Engelmann S, Lina G, Bröker BM.

Infect Immun. 2004 Jul;72(7):4061-71.


Combined treatment with ramipril and metoprolol prevents changes in the creatine kinase isoenzyme system and improves hemodynamic function in rat hearts after myocardial infarction.

Theres HP, Wagner KD, Romberg D, Feig C, Strube S, Leiterer KP, Günther J, Stangl K, Baumann G, Schimke I.

Cardiovasc Drugs Ther. 2000 Dec;14(6):597-606.


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