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Items: 20

1.

The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation.

Palangat M, Anastasakis DG, Fei DL, Lindblad KE, Bradley R, Hourigan CS, Hafner M, Larson DR.

Genes Dev. 2019 May 1;33(9-10):482-497. doi: 10.1101/gad.319590.118. Epub 2019 Mar 6.

PMID:
30842218
2.

Mitochondrial One-Carbon Pathway Supports Cytosolic Folate Integrity in Cancer Cells.

Zheng Y, Lin TY, Lee G, Paddock MN, Momb J, Cheng Z, Li Q, Fei DL, Stein BD, Ramsamooj S, Zhang G, Blenis J, Cantley LC.

Cell. 2018 Nov 29;175(6):1546-1560.e17. doi: 10.1016/j.cell.2018.09.041.

PMID:
30500537
3.

Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1.

Fei DL, Zhen T, Durham B, Ferrarone J, Zhang T, Garrett L, Yoshimi A, Abdel-Wahab O, Bradley RK, Liu P, Varmus H.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10437-E10446. doi: 10.1073/pnas.1812669115. Epub 2018 Oct 15.

4.

Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.

Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, Jin K, Nguyen DM, Sands LR, Marchetti F, Abreu MT, Cobb MH, Capobianco AJ, Lee E, Robbins DJ.

Sci Signal. 2017 Jun 27;10(485). pii: eaak9916. doi: 10.1126/scisignal.aak9916.

5.

The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expression.

Winterbottom EF, Koestler DC, Fei DL, Wika E, Capobianco AJ, Marsit CJ, Karagas MR, Robbins DJ.

Environ Health. 2017 Jun 14;16(1):59. doi: 10.1186/s12940-017-0267-8.

6.

Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.

Fei DL, Motowski H, Chatrikhi R, Prasad S, Yu J, Gao S, Kielkopf CL, Bradley RK, Varmus H.

PLoS Genet. 2016 Oct 24;12(10):e1006384. doi: 10.1371/journal.pgen.1006384. eCollection 2016 Oct.

7.

Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context-Dependent Manner.

Li B, Giambelli C, Tang B, Winterbottom E, Long J, Jin K, Wang Z, Fei DL, Nguyen DM, Athar M, Wang B, Subbarayan PR, Wang L, Rai P, Ardalan B, Capobianco AJ, Robbins DJ.

Mol Pharmacol. 2016 Feb;89(2):226-32. doi: 10.1124/mol.115.100867. Epub 2015 Nov 16.

8.

GLI3 Links Environmental Arsenic Exposure and Human Fetal Growth.

Winterbottom EF, Fei DL, Koestler DC, Giambelli C, Wika E, Capobianco AJ, Lee E, Marsit CJ, Karagas MR, Robbins DJ.

EBioMedicine. 2015 May 1;2(6):536-43. doi: 10.1016/j.ebiom.2015.04.019. eCollection 2015 Jun.

9.

In utero arsenic exposure and fetal immune repertoire in a US pregnancy cohort.

Nadeau KC, Li Z, Farzan S, Koestler D, Robbins D, Fei DL, Malipatlolla M, Maecker H, Enelow R, Korrick S, Karagas MR.

Clin Immunol. 2014 Dec;155(2):188-97. doi: 10.1016/j.clim.2014.09.004. Epub 2014 Sep 16.

10.

Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma.

Wang Z, Da Silva TG, Jin K, Han X, Ranganathan P, Zhu X, Sanchez-Mejias A, Bai F, Li B, Fei DL, Weaver K, Carpio RV, Moscowitz AE, Koshenkov VP, Sanchez L, Sparling L, Pei XH, Franceschi D, Ribeiro A, Robbins DJ, Livingstone AS, Capobianco AJ.

Cancer Res. 2014 Nov 1;74(21):6364-74. doi: 10.1158/0008-5472.CAN-14-2051. Epub 2014 Aug 27.

11.

Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis.

Li B, Flaveny CA, Giambelli C, Fei DL, Han L, Hang BI, Bai F, Pei XH, Nose V, Burlingame O, Capobianco AJ, Orton D, Lee E, Robbins DJ.

PLoS One. 2014 Jul 8;9(7):e101969. doi: 10.1371/journal.pone.0101969. eCollection 2014.

12.

Pyrvinium attenuates Hedgehog signaling downstream of smoothened.

Li B, Fei DL, Flaveny CA, Dahmane N, Baubet V, Wang Z, Bai F, Pei XH, Rodriguez-Blanco J, Hang B, Orton D, Han L, Wang B, Capobianco AJ, Lee E, Robbins DJ.

Cancer Res. 2014 Sep 1;74(17):4811-21. doi: 10.1158/0008-5472.CAN-14-0317. Epub 2014 Jul 3.

13.

Clinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancer.

Sverrisson EF, Zens MS, Fei DL, Andrews A, Schned A, Robbins D, Kelsey KT, Li H, DiRenzo J, Karagas MR, Seigne JD.

Urol Oncol. 2014 Jul;32(5):539-45. doi: 10.1016/j.urolonc.2014.03.006. Epub 2014 May 22.

14.

Association between In Utero arsenic exposure, placental gene expression, and infant birth weight: a US birth cohort study.

Fei DL, Koestler DC, Li Z, Giambelli C, Sanchez-Mejias A, Gosse JA, Marsit CJ, Karagas MR, Robbins DJ.

Environ Health. 2013 Jul 16;12:58. doi: 10.1186/1476-069X-12-58.

15.

Repression of exogenous gene expression by the retinoic acid target gene G0S2.

Ma T, Dong JP, Sekula DJ, Fei DL, Lamph WW, Henderson M, Lu Y, Blumen S, Freemantle SJ, Dmitrovsky E.

Int J Oncol. 2013 May;42(5):1743-53. doi: 10.3892/ijo.2013.1876. Epub 2013 Mar 28.

16.

The Hedgehog signal transduction network.

Robbins DJ, Fei DL, Riobo NA.

Sci Signal. 2012 Oct 16;5(246):re6. doi: 10.1126/scisignal.2002906. Review.

17.

Hedgehog signaling regulates bladder cancer growth and tumorigenicity.

Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, Bejarano P, Capobianco AJ, Robbins DJ.

Cancer Res. 2012 Sep 1;72(17):4449-58. Epub 2012 Jul 19.

18.

Repurposing an old anti-fungal drug as a Hedgehog inhibitor.

Giambelli C, Fei DL, Wang H, Robbins DJ.

Protein Cell. 2010 May;1(5):417-8. doi: 10.1007/s13238-010-0063-5. No abstract available.

19.

Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors.

Fei DL, Li H, Kozul CD, Black KE, Singh S, Gosse JA, DiRenzo J, Martin KA, Wang B, Hamilton JW, Karagas MR, Robbins DJ.

Cancer Res. 2010 Mar 1;70(5):1981-8. doi: 10.1158/0008-5472.CAN-09-2898. Epub 2010 Feb 23.

20.

G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling.

Ogden SK, Fei DL, Schilling NS, Ahmed YF, Hwa J, Robbins DJ.

Nature. 2008 Dec 18;456(7224):967-70. doi: 10.1038/nature07459.

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