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Items: 36

1.

4-miRNA Score Predicts the Individual Metastatic Risk of Renal Cell Carcinoma Patients.

Heinzelmann J, Arndt M, Pleyers R, Fehlmann T, Hoelters S, Zeuschner P, Vogt A, Pryalukhin A, Schaeffeler E, Bohle RM, Gajda M, Janssen M, Stoeckle M, Junker K.

Ann Surg Oncol. 2019 Jul 3. doi: 10.1245/s10434-019-07578-3. [Epub ahead of print]

PMID:
31270716
2.

Prospect and challenge of detecting dynamic gene copy number increases in stem cells by whole genome sequencing.

Fischer U, Backes C, Fehlmann T, Galata V, Keller A, Meese E.

J Mol Med (Berl). 2019 Aug;97(8):1099-1111. doi: 10.1007/s00109-019-01792-y. Epub 2019 May 27.

PMID:
31134286
3.

Spring is in the air: seasonal profiles indicate vernal change of miRNA activity.

Ludwig N, Hecksteden A, Kahraman M, Fehlmann T, Laufer T, Kern F, Meyer T, Meese E, Keller A, Backes C.

RNA Biol. 2019 Aug;16(8):1034-1043. doi: 10.1080/15476286.2019.1612217. Epub 2019 May 10.

PMID:
31035857
4.

The sncRNA Zoo: a repository for circulating small noncoding RNAs in animals.

Fehlmann T, Backes C, Pirritano M, Laufer T, Galata V, Kern F, Kahraman M, Gasparoni G, Ludwig N, Lenhof HP, Gregersen HA, Francke R, Meese E, Simon M, Keller A.

Nucleic Acids Res. 2019 May 21;47(9):4431-4441. doi: 10.1093/nar/gkz227.

5.

An estimate of the total number of true human miRNAs.

Alles J, Fehlmann T, Fischer U, Backes C, Galata V, Minet M, Hart M, Abu-Halima M, Grässer FA, Lenhof HP, Keller A, Meese E.

Nucleic Acids Res. 2019 Apr 23;47(7):3353-3364. doi: 10.1093/nar/gkz097.

6.

Conservation and Relevance of Pharmacophore Point Types.

Fehlmann T, Hutter MC.

J Chem Inf Model. 2019 Apr 22;59(4):1314-1323. doi: 10.1021/acs.jcim.8b00757. Epub 2019 Mar 12.

PMID:
30807146
7.

Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activity.

Fehlmann T, Laufer T, Backes C, Kahramann M, Alles J, Fischer U, Minet M, Ludwig N, Kern F, Kehl T, Galata V, Düsterloh A, Schrörs H, Kohlhaas J, Bals R, Huwer H, Geffers L, Krüger R, Balling R, Lenhof HP, Meese E, Keller A.

RNA Biol. 2019 Jan;16(1):93-103. doi: 10.1080/15476286.2018.1559689. Epub 2018 Dec 26.

PMID:
30567465
8.

Epstein-Barr Virus Infection of Cell Lines Derived from Diffuse Large B-Cell Lymphomas Alters MicroRNA Loading of the Ago2 Complex.

Ayoubian H, Ludwig N, Fehlmann T, Menegatti J, Gröger L, Anastasiadou E, Trivedi P, Keller A, Meese E, Grässer FA.

J Virol. 2019 Jan 17;93(3). pii: e01297-18. doi: 10.1128/JVI.01297-18. Print 2019 Feb 1.

9.

PLSDB: a resource of complete bacterial plasmids.

Galata V, Fehlmann T, Backes C, Keller A.

Nucleic Acids Res. 2019 Jan 8;47(D1):D195-D202. doi: 10.1093/nar/gky1050.

10.

Modulation of intracellular calcium signaling by microRNA-34a-5p.

Diener C, Hart M, Alansary D, Poth V, Walch-Rückheim B, Menegatti J, Grässer F, Fehlmann T, Rheinheimer S, Niemeyer BA, Lenhof HP, Keller A, Meese E.

Cell Death Dis. 2018 Sep 27;9(10):1008. doi: 10.1038/s41419-018-1050-7.

11.

Next Generation Sequencing Analysis of Total Small Noncoding RNAs from Low Input RNA from Dried Blood Sampling.

Pirritano M, Fehlmann T, Laufer T, Ludwig N, Gasparoni G, Li Y, Meese E, Keller A, Simon M.

Anal Chem. 2018 Oct 16;90(20):11791-11796. doi: 10.1021/acs.analchem.8b03557. Epub 2018 Sep 25.

PMID:
30198258
12.

MicroRNA in diagnosis and therapy monitoring of early-stage triple-negative breast cancer.

Kahraman M, Röske A, Laufer T, Fehlmann T, Backes C, Kern F, Kohlhaas J, Schrörs H, Saiz A, Zabler C, Ludwig N, Fasching PA, Strick R, Rübner M, Beckmann MW, Meese E, Keller A, Schrauder MG.

Sci Rep. 2018 Aug 2;8(1):11584. doi: 10.1038/s41598-018-29917-2.

13.

Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development.

Keller A, Fehlmann T, Ludwig N, Kahraman M, Laufer T, Backes C, Vogelmeier C, Diener C, Biertz F, Herr C, Jörres RA, Lenhof HP, Meese E, Bals R; COSYCONET Study Group.

Genomics Proteomics Bioinformatics. 2018 Jun;16(3):162-171. doi: 10.1016/j.gpb.2018.06.001. Epub 2018 Jul 5.

14.

The deterministic role of 5-mers in microRNA-gene targeting.

Hart M, Kern F, Backes C, Rheinheimer S, Fehlmann T, Keller A, Meese E.

RNA Biol. 2018;15(6):819-825. doi: 10.1080/15476286.2018.1462652. Epub 2018 May 11.

15.

Small ncRNA-Seq Results of Human Tissues: Variations Depending on Sample Integrity.

Ludwig N, Fehlmann T, Galata V, Franke A, Backes C, Meese E, Keller A.

Clin Chem. 2018 Jul;64(7):1074-1084. doi: 10.1373/clinchem.2017.285767. Epub 2018 Apr 24.

16.

About miRNAs, miRNA seeds, target genes and target pathways.

Kehl T, Backes C, Kern F, Fehlmann T, Ludwig N, Meese E, Lenhof HP, Keller A.

Oncotarget. 2017 Nov 9;8(63):107167-107175. doi: 10.18632/oncotarget.22363. eCollection 2017 Dec 5.

17.

A high-resolution map of the human small non-coding transcriptome.

Fehlmann T, Backes C, Alles J, Fischer U, Hart M, Kern F, Langseth H, Rounge T, Umu SU, Kahraman M, Laufer T, Haas J, Staehler C, Ludwig N, Hübenthal M, Meder B, Franke A, Lenhof HP, Meese E, Keller A.

Bioinformatics. 2018 May 15;34(10):1621-1628. doi: 10.1093/bioinformatics/btx814.

PMID:
29281000
18.

A review of databases predicting the effects of SNPs in miRNA genes or miRNA-binding sites.

Fehlmann T, Sahay S, Keller A, Backes C.

Brief Bioinform. 2019 May 21;20(3):1011-1020. doi: 10.1093/bib/bbx155.

PMID:
29186316
19.

Micro-ribonucleic acids and extracellular vesicles repertoire in the spent culture media is altered in women undergoing In Vitro Fertilization.

Abu-Halima M, Häusler S, Backes C, Fehlmann T, Staib C, Nestel S, Nazarenko I, Meese E, Keller A.

Sci Rep. 2017 Oct 19;7(1):13525. doi: 10.1038/s41598-017-13683-8.

20.

miRCarta: a central repository for collecting miRNA candidates.

Backes C, Fehlmann T, Kern F, Kehl T, Lenhof HP, Meese E, Keller A.

Nucleic Acids Res. 2018 Jan 4;46(D1):D160-D167. doi: 10.1093/nar/gkx851.

21.

Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy.

Sedaghat-Hamedani F, Haas J, Zhu F, Geier C, Kayvanpour E, Liss M, Lai A, Frese K, Pribe-Wolferts R, Amr A, Li DT, Samani OS, Carstensen A, Bordalo DM, Müller M, Fischer C, Shao J, Wang J, Nie M, Yuan L, Haßfeld S, Schwartz C, Zhou M, Zhou Z, Shu Y, Wang M, Huang K, Zeng Q, Cheng L, Fehlmann T, Ehlermann P, Keller A, Dieterich C, Streckfuß-Bömeke K, Liao Y, Gotthardt M, Katus HA, Meder B.

Eur Heart J. 2017 Dec 7;38(46):3449-3460. doi: 10.1093/eurheartj/ehx545.

PMID:
29029073
22.

IMOTA: an interactive multi-omics tissue atlas for the analysis of human miRNA-target interactions.

Palmieri V, Backes C, Ludwig N, Fehlmann T, Kern F, Meese E, Keller A.

Nucleic Acids Res. 2018 Jan 4;46(D1):D770-D775. doi: 10.1093/nar/gkx701.

23.

Web-based NGS data analysis using miRMaster: a large-scale meta-analysis of human miRNAs.

Fehlmann T, Backes C, Kahraman M, Haas J, Ludwig N, Posch AE, Würstle ML, Hübenthal M, Franke A, Meder B, Meese E, Keller A.

Nucleic Acids Res. 2017 Sep 6;45(15):8731-8744. doi: 10.1093/nar/gkx595.

24.

Bias in recent miRBase annotations potentially associated with RNA quality issues.

Ludwig N, Becker M, Schumann T, Speer T, Fehlmann T, Keller A, Meese E.

Sci Rep. 2017 Jul 12;7(1):5162. doi: 10.1038/s41598-017-05070-0.

25.

Technical Stability and Biological Variability in MicroRNAs from Dried Blood Spots: A Lung Cancer Therapy-Monitoring Showcase.

Kahraman M, Laufer T, Backes C, Schrörs H, Fehlmann T, Ludwig N, Kohlhaas J, Meese E, Wehler T, Bals R, Keller A.

Clin Chem. 2017 Sep;63(9):1476-1488. doi: 10.1373/clinchem.2017.271619. Epub 2017 Jul 5.

26.

BusyBee Web: metagenomic data analysis by bootstrapped supervised binning and annotation.

Laczny CC, Kiefer C, Galata V, Fehlmann T, Backes C, Keller A.

Nucleic Acids Res. 2017 Jul 3;45(W1):W171-W179. doi: 10.1093/nar/gkx348.

27.

Exploring ncRNAs in Alzheimer's disease by miRMaster.

Fehlmann T, Meese E, Keller A.

Oncotarget. 2017 Jan 17;8(3):3771-3772. doi: 10.18632/oncotarget.14054. No abstract available.

28.

miRNAs in Ancient Tissue Specimens of the Tyrolean Iceman.

Keller A, Kreis S, Leidinger P, Maixner F, Ludwig N, Backes C, Galata V, Guerriero G, Fehlmann T, Franke A, Meder B, Zink A, Meese E.

Mol Biol Evol. 2017 Apr 1;34(4):793-801. doi: 10.1093/molbev/msw291.

PMID:
28025275
29.

cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs.

Fehlmann T, Reinheimer S, Geng C, Su X, Drmanac S, Alexeev A, Zhang C, Backes C, Ludwig N, Hart M, An D, Zhu Z, Xu C, Chen A, Ni M, Liu J, Li Y, Poulter M, Li Y, Stähler C, Drmanac R, Xu X, Meese E, Keller A.

Clin Epigenetics. 2016 Nov 21;8:123. eCollection 2016.

30.

Distribution of microRNA biomarker candidates in solid tissues and body fluids.

Fehlmann T, Ludwig N, Backes C, Meese E, Keller A.

RNA Biol. 2016 Nov;13(11):1084-1088. Epub 2016 Sep 29.

31.

miRPathDB: a new dictionary on microRNAs and target pathways.

Backes C, Kehl T, Stöckel D, Fehlmann T, Schneider L, Meese E, Lenhof HP, Keller A.

Nucleic Acids Res. 2017 Jan 4;45(D1):D90-D96. doi: 10.1093/nar/gkw926. Epub 2016 Oct 13.

32.

Paired proteomics, transcriptomics and miRNomics in non-small cell lung cancers: known and novel signaling cascades.

Backes C, Ludwig N, Leidinger P, Huwer H, Tenzer S, Fehlmann T, Franke A, Meese E, Lenhof HP, Keller A.

Oncotarget. 2016 Nov 1;7(44):71514-71525. doi: 10.18632/oncotarget.11723.

33.

Identification of miR-34a-target interactions by a combined network based and experimental approach.

Hart M, Rheinheimer S, Leidinger P, Backes C, Menegatti J, Fehlmann T, Grässer F, Keller A, Meese E.

Oncotarget. 2016 Jun 7;7(23):34288-99. doi: 10.18632/oncotarget.9103.

34.

MiRTargetLink--miRNAs, Genes and Interaction Networks.

Hamberg M, Backes C, Fehlmann T, Hart M, Meder B, Meese E, Keller A.

Int J Mol Sci. 2016 Apr 14;17(4):564. doi: 10.3390/ijms17040564.

35.

Distribution of miRNA expression across human tissues.

Ludwig N, Leidinger P, Becker K, Backes C, Fehlmann T, Pallasch C, Rheinheimer S, Meder B, Stähler C, Meese E, Keller A.

Nucleic Acids Res. 2016 May 5;44(8):3865-77. doi: 10.1093/nar/gkw116. Epub 2016 Feb 25.

36.

Deep characterization of blood cell miRNomes by NGS.

Schwarz EC, Backes C, Knörck A, Ludwig N, Leidinger P, Hoxha C, Schwär G, Grossmann T, Müller SC, Hart M, Haas J, Galata V, Müller I, Fehlmann T, Eichler H, Franke A, Meder B, Meese E, Hoth M, Keller A.

Cell Mol Life Sci. 2016 Aug;73(16):3169-81. doi: 10.1007/s00018-016-2154-9. Epub 2016 Feb 13.

PMID:
26874686

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