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Metastatic Spine Disease: Should Patients With Short Life Expectancy Be Denied Surgical Care? An International Retrospective Cohort Study.

Dea N, Versteeg AL, Sahgal A, Verlaan JJ, Charest-Morin R, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Lazary A, Fehlings MG, Clarke MJ, Arnold PM, Boriani S, Bettegowda C, Laufer I, Gokaslan ZL, Fisher CG.

Neurosurgery. 2019 Nov 6. pii: nyz472. doi: 10.1093/neuros/nyz472. [Epub ahead of print]


A combination of mesenchymal stem cells and scaffolds promotes motor functional recovery in spinal cord injury: a systematic review and meta-analysis.

Yousefifard M, Nasseri Maleki S, Askarian-Amiri S, Vaccaro AR, Chapman JR, Fehlings MG, Hosseini M, Rahimi-Movaghar V.

J Neurosurg Spine. 2019 Nov 1:1-16. doi: 10.3171/2019.8.SPINE19201. [Epub ahead of print] Review.


The Effect of Older Age on the Perioperative Outcomes of Spinal Fusion Surgery in Patients With Lumbar Degenerative Disc Disease With Spondylolisthesis: A Propensity Score-Matched Analysis.

Badhiwala JH, Karmur BS, Hachem LD, Wilson JRF, Jiang F, Jaja B, Nouri A, Witiw CD, Nassiri F, Fehlings MG, Wilson JR.

Neurosurgery. 2019 Oct 23. pii: nyz444. doi: 10.1093/neuros/nyz444. [Epub ahead of print]


An Age-old Debate: Anterior Versus Posterior Surgery for Ossification of the Posterior Longitudinal Ligament.

Moghaddamjou A, Fehlings MG.

Neurospine. 2019 Sep;16(3):544-547. doi: 10.14245/ns.19edi.014. Epub 2019 Sep 30. No abstract available.


Recovery priorities in degenerative cervical myelopathy: a cross-sectional survey of an international, online community of patients.

Davies B, Mowforth O, Sadler I, Aarabi B, Kwon B, Kurpad S, Harrop JS, Wilson JR, Grossman R, Fehlings MG, Kotter M.

BMJ Open. 2019 Oct 10;9(10):e031486. doi: 10.1136/bmjopen-2019-031486.


Comparison of the Inpatient Complications and Health Care Costs of Anterior versus Posterior Cervical Decompression and Fusion in Patients with Multilevel Degenerative Cervical Myelopathy: A Retrospective Propensity Score-Matched Analysis.

Badhiwala JH, Ellenbogen Y, Khan O, Nouri A, Jiang F, Wilson JRF, Jaja B, Witiw CD, Nassiri F, Fehlings MG, Wilson JR.

World Neurosurg. 2019 Sep 28. pii: S1878-8750(19)32576-8. doi: 10.1016/j.wneu.2019.09.132. [Epub ahead of print]


The graded redefined assessment of strength sensibility and prehension version 2 (GV2): Psychometric properties.

Kalsi-Ryan S, Chan C, Verrier M, Curt A, Fehlings M, Bolliger M, Velstra IM; GRASSP Cross Sectional Study Team; GRASSP Longitudinal Study Team.

J Spinal Cord Med. 2019 Oct;42(sup1):149-157. doi: 10.1080/10790268.2019.1616950.


Is there any gender or age-related discrepancy in the waiting time for each step in the surgical management of acute traumatic cervical spinal cord injury?

Furlan JC, Craven BC, Fehlings MG.

J Spinal Cord Med. 2019 Oct;42(sup1):233-241. doi: 10.1080/10790268.2019.1614291.


Sex-related discrepancies in the epidemiology, injury characteristics and outcomes after acute spine trauma: A retrospective cohort study.

Furlan JC, Craven BC, Fehlings MG.

J Spinal Cord Med. 2019 Oct;42(sup1):10-20. doi: 10.1080/10790268.2019.1607055.


The case for revisiting central cord syndrome.

Badhiwala JH, Wilson JR, Fehlings MG.

Spinal Cord. 2019 Sep 13. doi: 10.1038/s41393-019-0354-5. [Epub ahead of print] Review. No abstract available.


Myélopathie cervicale dégénérative: Diagnostic et prise en charge en première ligne.

Milligan J, Ryan K, Fehlings M, Bauman C.

Can Fam Physician. 2019 Sep;65(9):e379-e385. Review. French.

Free PMC Article

Degenerative cervical myelopathy: Diagnosis and management in primary care.

Milligan J, Ryan K, Fehlings M, Bauman C.

Can Fam Physician. 2019 Sep;65(9):619-624. Review.


Late-differentiated effector neoantigen-specific CD8+ T cells are enriched in peripheral blood of non-small cell lung carcinoma patients responding to atezolizumab treatment.

Fehlings M, Jhunjhunwala S, Kowanetz M, O'Gorman WE, Hegde PS, Sumatoh H, Lee BH, Nardin A, Becht E, Flynn S, Ballinger M, Newell EW, Yadav M.

J Immunother Cancer. 2019 Sep 12;7(1):249. doi: 10.1186/s40425-019-0695-9.


Duration of symptoms in the quantification of upper limb disability and impairment for individuals with mild degenerative cervical myelopathy (DCM).

Kalsi-Ryan S, Clout J, Rostami P, Massicotte EM, Fehlings MG.

PLoS One. 2019 Sep 9;14(9):e0222134. doi: 10.1371/journal.pone.0222134. eCollection 2019.


Patient satisfaction with treatment outcomes after surgery and/or radiotherapy for spinal metastases.

Versteeg AL, Sahgal A, Kawahara N, Rhines LD, Sciubba DM, Weber MH, Lazary Á, Fehlings MG, Schuster JM, Clarke MJ, Arnold PM, Boriani S, Bettegowda C, Gokaslan ZL, Fisher CG; AOSpine Knowledge Forum Tumor.

Cancer. 2019 Sep 6. doi: 10.1002/cncr.32465. [Epub ahead of print]


Degenerative Cervical Myelopathy; A Review of the Latest Advances and Future Directions in Management.

Wilson JRF, Badhiwala JH, Moghaddamjou A, Martin AR, Fehlings MG.

Neurospine. 2019 Sep;16(3):494-505. doi: 10.14245/ns.1938314.157. Epub 2019 Aug 26.


Quantification of computational geometric congruence in surface-based registration for spinal intra-operative three-dimensional navigation.

Guha D, Jakubovic R, Leung MK, Ginsberg HJ, Fehlings MG, Mainprize TG, Yee A, Yang VXD.

PLoS One. 2019 Aug 26;14(8):e0207137. doi: 10.1371/journal.pone.0207137. eCollection 2019.


The changes in systemic monocytes in humans undergoing surgical decompression for degenerative cervical myelopathy may influence clinical neurological recovery.

Vidal PM, Ulndreaj A, Tetreault L, Hong J, Fehlings MG.

J Neuroimmunol. 2019 Nov 15;336:577024. doi: 10.1016/j.jneuroim.2019.577024. Epub 2019 Aug 16.


National Spinal Cord Injury Registry of Iran (NSCIR-IR) - a critical appraisal of its strengths and weaknesses.

Sharif-Alhoseini M, Azadmanjir Z, Sadeghi-Naini M, Ghodsi Z, Naghdi K, Mohammadzadeh M, AzarHomayoun A, Zendehdel K, Khormali M, Sadeghian F, Jazayeri SB, Sehat M, Pirnejad H, Benzel EC, O'Reilly G, Fehlings MG, Vaccaro AR, Rahimi-Movaghar V.

Chin J Traumatol. 2019 Oct;22(5):300-303. doi: 10.1016/j.cjtee.2019.05.003. Epub 2019 Jul 13.


Intraoperative Error Propagation in 3-Dimensional Spinal Navigation From Nonsegmental Registration: A Prospective Cadaveric and Clinical Study.

Guha D, Jakubovic R, Gupta S, Fehlings MG, Mainprize TG, Yee A, Yang VXD.

Global Spine J. 2019 Aug;9(5):512-520. doi: 10.1177/2192568218804556. Epub 2018 Oct 9.


The Effect of Tobacco Smoking on Adverse Events Following Adult Complex Deformity Surgery: Analysis of 270 Patients from The Prospective, Multi-center Scoli-RISK-1 study.

Wilson JRF, Jiang F, Badhiwala JH, Shaffrey CL, Carreon LY, Cheung KMC, Dahl BT, Ames CP, Boachie-Adjei O, Dekutoski MB, Lewis SJ, Matsuyama Y, Mehdian H, Pellisé F, Qiu Y, Schwab FJ, Lenke LG, Fehlings MG.

Spine (Phila Pa 1976). 2019 Aug 13. doi: 10.1097/BRS.0000000000003200. [Epub ahead of print]


Association of neurologic deficits with surgical outcomes and health-related quality of life after treatment for metastatic epidural spinal cord compression.

Barzilai O, Versteeg AL, Goodwin CR, Sahgal A, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Lazary A, Fehlings MG, Clarke MJ, Arnold PM, Boriani S, Bettegowda C, Gokaslan ZL, Fisher CG, Laufer I; AOSpine Knowledge Forum Tumor.

Cancer. 2019 Aug 13. doi: 10.1002/cncr.32420. [Epub ahead of print]


Advancing spinal fellowship training: an international multi-centre educational perspective.

Kumaria A, Bateman AH, Eames N, Fehlings MG, Goldstein C, Meyer B, Paquette SJ, Yee AJM.

Eur Spine J. 2019 Nov;28(11):2437-2443. doi: 10.1007/s00586-019-06098-8. Epub 2019 Aug 12. Review.


MRI in traumatic spinal cord injury: from clinical assessment to neuroimaging biomarkers.

Freund P, Seif M, Weiskopf N, Friston K, Fehlings MG, Thompson AJ, Curt A.

Lancet Neurol. 2019 Dec;18(12):1123-1135. doi: 10.1016/S1474-4422(19)30138-3. Epub 2019 Aug 9. Review.


Acute Adverse Events After Spinal Cord Injury and Their Relationship to Long-term Neurologic and Functional Outcomes: Analysis From the North American Clinical Trials Network for Spinal Cord Injury.

Jiang F, Jaja BNR, Kurpad SN, Badhiwala JH, Aarabi B, Grossman RG, Harrop JS, Guest JD, Schär RT, Shaffrey CI, Boakye M, Toups EG, Wilson JR, Fehlings MG; North American Clinical Trials Network Collaborators.

Crit Care Med. 2019 Nov;47(11):e854-e862. doi: 10.1097/CCM.0000000000003937.


Incomplete Spinal Cord Injury Reverses the Level-Dependence of Spinal Cord Injury Immune Deficiency Syndrome.

Hong J, Chang A, Liu Y, Wang J, Fehlings MG.

Int J Mol Sci. 2019 Aug 1;20(15). pii: E3762. doi: 10.3390/ijms20153762.


Demographics, presentation and symptoms of patients with Klippel-Feil syndrome: analysis of a global patient-reported registry.

Nouri A, Patel K, Evans H, Saleh M, Kotter MRN, Heary RF, Tessitore E, Fehlings MG, Cheng JS.

Eur Spine J. 2019 Oct;28(10):2257-2265. doi: 10.1007/s00586-019-06084-0. Epub 2019 Jul 30.


Clinical presentation, management and outcomes of sacral metastases: a multicenter, retrospective cohort study.

Charest-Morin R, Fisher CG, Versteeg AL, Sahgal A, Varga PP, Sciubba DM, Schuster JM, Weber MH, Clarke MJ, Rhines LD, Boriani S, Bettegowda C, Fehlings MG, Arnold PM, Gokaslan ZL, Dea N.

Ann Transl Med. 2019 May;7(10):214. doi: 10.21037/atm.2019.04.88.


The effects of human immunoglobulin G on enhancing tissue protection and neurobehavioral recovery after traumatic cervical spinal cord injury are mediated through the neurovascular unit.

Chio JCT, Wang J, Badner A, Hong J, Surendran V, Fehlings MG.

J Neuroinflammation. 2019 Jul 9;16(1):141. doi: 10.1186/s12974-019-1518-0.


The discrepancy between functional outcome and self-reported health status after surgery for degenerative cervical myelopathy.

Tetreault LA, Zhu MP, Howard RM, Sorefan-Mangou F, Patel AA, Schroeder GD, Massicotte EM, Bhadiwala JH, Fehlings MG, Wilson JR.

Spine J. 2019 Nov;19(11):1809-1815. doi: 10.1016/j.spinee.2019.06.026. Epub 2019 Jul 3.


A Balanced Perspective on Surgery of the Craniovertebral Junction.

Fehlings MG, Badhiwala JH.

Neurospine. 2019 Jun;16(2):216-218. doi: 10.14245/ns.19edi.007. Epub 2019 Jun 30. No abstract available.


A Systematic Review of Definitions for Neurological Complications and Disease Progression in Patients Treated Surgically for Degenerative Cervical Myelopathy.

Tetreault L, Lange SF, Chotai S, Kryshtalskyj MT, Martin AR, Ahuja CS, Wilson JR, Davies BM, Nouri A, Devin C, Fehlings MG.

Spine (Phila Pa 1976). 2019 Sep;44(18):1318-1331. doi: 10.1097/BRS.0000000000003066.


Regeneration of Spinal Cord Connectivity Through Stem Cell Transplantation and Biomaterial Scaffolds.

Katoh H, Yokota K, Fehlings MG.

Front Cell Neurosci. 2019 Jun 6;13:248. doi: 10.3389/fncel.2019.00248. eCollection 2019. Review.


Predicting Outcomes After Surgical Decompression for Mild Degenerative Cervical Myelopathy: Moving Beyond the mJOA to Identify Surgical Candidates.

Badhiwala JH, Hachem LD, Merali Z, Witiw CD, Nassiri F, Akbar MA, Almenawer SA, Schomacher M, Wilson JR, Fehlings MG.

Neurosurgery. 2019 Jun 21. pii: nyz160. doi: 10.1093/neuros/nyz160. [Epub ahead of print]


Examining the fundamental biology of a novel population of directly reprogrammed human neural precursor cells.

Ahlfors JE, Azimi A, El-Ayoubi R, Velumian A, Vonderwalde I, Boscher C, Mihai O, Mani S, Samoilova M, Khazaei M, Fehlings MG, Morshead CM.

Stem Cell Res Ther. 2019 Jun 13;10(1):166. doi: 10.1186/s13287-019-1255-4.


Evolution and Advancement of Adult Spinal Deformity Research and Clinical Care: An Overview of the Scoli-RISK-1 Study.

Cerpa M, Lenke LG, Fehlings MG, Shaffrey CI, Cheung KMC, Carreon LY.

Global Spine J. 2019 May;9(1 Suppl):8S-14S. doi: 10.1177/2192568219828729. Epub 2019 May 8.


Management of Acute Traumatic Central Cord Syndrome: A Narrative Review.

Divi SN, Schroeder GD, Mangan JJ, Tadley M, Ramey WL, Badhiwala JH, Fehlings MG, Oner FC, Kandziora F, Benneker LM, Vialle EN, Rajasekaran S, Chapman JR, Vaccaro AR.

Global Spine J. 2019 May;9(1 Suppl):89S-97S. doi: 10.1177/2192568219830943. Epub 2019 May 8.


RE-CODE DCM (REsearch Objectives and Common Data Elements for Degenerative Cervical Myelopathy): A Consensus Process to Improve Research Efficiency in DCM, Through Establishment of a Standardized Dataset for Clinical Research and the Definition of the Research Priorities.

Davies BM, Khan DZ, Mowforth OD, McNair AGK, Gronlund T, Kolias AG, Tetreault L, Starkey ML, Sadler I, Sarewitz E, Houlton D, Carter J, Kalsi-Ryan S, Aarabi B, Kwon BK, Kurpad SN, Harrop J, Wilson JR, Grossman R, Curt A, Fehlings MG, Kotter MRN.

Global Spine J. 2019 May;9(1 Suppl):65S-76S. doi: 10.1177/2192568219832855. Epub 2019 May 8.


AOSpine Knowledge Forums: Research in Motion.

Samartzis D, Germscheid NM, Fehlings MG, Fisher CG, de Kleuver M, Öner FC, Yoon ST, Vialle LR.

Global Spine J. 2019 May;9(1 Suppl):5S-7S. doi: 10.1177/2192568219845647. Epub 2019 May 8. No abstract available.


Development and Implementation of Clinical Practice Guidelines: An Update and Synthesis of the Literature With a Focus in Application to Spinal Conditions.

Tetreault L, Nater A, Garwood P, Badhiwala JH, Wilson JR, Fehlings MG.

Global Spine J. 2019 May;9(1 Suppl):53S-64S. doi: 10.1177/2192568219831689. Epub 2019 May 8.


Predictors of Return to Normal Neurological Function After Surgery for Moderate and Severe Degenerative Cervical Myelopathy: An Analysis of A Global AOSpine Cohort of Patients.

De la Garza Ramos R, Nouri A, Nakhla J, Echt M, Gelfand Y, Patel SK, Nasser R, Cheng JS, Yassari R, Fehlings MG.

Neurosurgery. 2019 Nov 1;85(5):E917-E923. doi: 10.1093/neuros/nyz178.


AOSpine Global Survey: International Trends in Utilization of Magnetic Resonance Imaging/Computed Tomography for Spinal Trauma and Spinal Cord Injury across AO Regions.

Shabani S, Kaushal M, Soliman HM, Nguyen HS, Aarabi B, Fehlings MG, Kotter M, Kwon BK, Harrop J, Kurpad SN.

J Neurotrauma. 2019 Jun 21. doi: 10.1089/neu.2019.6464. [Epub ahead of print]


Multiplex MHC Class I Tetramer Combined with Intranuclear Staining by Mass Cytometry.

Simoni Y, Fehlings M, Newell EW.

Methods Mol Biol. 2019;1989:147-158. doi: 10.1007/978-1-4939-9454-0_11.


Association of Pneumonia, Wound Infection, and Sepsis with Clinical Outcomes after Acute Traumatic Spinal Cord Injury.

Jaja BNR, Jiang F, Badhiwala JH, Schär R, Kurpad S, Grossman RG, Harrop JS, Guest JD, Toups EG, Shaffrey CI, Aarabi B, Boakye M, Fehlings MG, Wilson JR.

J Neurotrauma. 2019 Nov 1;36(21):3044-3050. doi: 10.1089/neu.2018.6245. Epub 2019 Jun 17.


Using a machine learning approach to predict outcome after surgery for degenerative cervical myelopathy.

Merali ZG, Witiw CD, Badhiwala JH, Wilson JR, Fehlings MG.

PLoS One. 2019 Apr 4;14(4):e0215133. doi: 10.1371/journal.pone.0215133. eCollection 2019.


A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils.

Janela B, Patel AA, Lau MC, Goh CC, Msallam R, Kong WT, Fehlings M, Hubert S, Lum J, Simoni Y, Malleret B, Zolezzi F, Chen J, Poidinger M, Satpathy AT, Briseno C, Wohn C, Malissen B, Murphy KM, Maini AA, Vanhoutte L, Guilliams M, Vial E, Hennequin L, Newell E, Ng LG, Musette P, Yona S, Hacini-Rachinel F, Ginhoux F.

Immunity. 2019 Apr 16;50(4):1069-1083.e8. doi: 10.1016/j.immuni.2019.03.001. Epub 2019 Mar 27.


Investigating the utility of intraoperative neurophysiological monitoring for anterior cervical discectomy and fusion: analysis of over 140,000 cases from the National (Nationwide) Inpatient Sample data set.

Badhiwala JH, Nassiri F, Witiw CD, Mansouri A, Almenawer SA, da Costa L, Fehlings MG, Wilson JR.

J Neurosurg Spine. 2019 Mar 29:1-11. doi: 10.3171/2019.1.SPINE181110. [Epub ahead of print]


Early Intravenous Infusion of Mesenchymal Stromal Cells Exerts a Tissue Source Age-Dependent Beneficial Effect on Neurovascular Integrity and Neurobehavioral Recovery After Traumatic Cervical Spinal Cord Injury.

Vawda R, Badner A, Hong J, Mikhail M, Lakhani A, Dragas R, Xhima K, Barretto T, Librach CL, Fehlings MG.

Stem Cells Transl Med. 2019 Jul;8(7):639-649. doi: 10.1002/sctm.18-0192. Epub 2019 Mar 26.


Endogenous Interleukin-10 Deficiency Exacerbates Vascular Pathology in Traumatic Cervical Spinal Cord Injury.

Badner A, Vidal PM, Hong J, Hacker J, Fehlings MG.

J Neurotrauma. 2019 Aug 1;36(15):2298-2307. doi: 10.1089/neu.2018.6081. Epub 2019 Apr 24.


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