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The Impact of Riluzole on Neurobehavioral Outcomes in Preclinical Models of Traumatic and Nontraumatic Spinal Cord Injury: Results From a Systematic Review of the Literature.

Tetreault LA, Zhu MP, Wilson JR, Karadimas SK, Fehlings MG.

Global Spine J. 2020 Apr;10(2):216-229. doi: 10.1177/2192568219835516. Epub 2019 May 12. Review.


Quantitative Assessment of Gait Characteristics in Degenerative Cervical Myelopathy: A Prospective Clinical Study.

Kalsi-Ryan S, Rienmueller AC, Riehm L, Chan C, Jin D, Martin AR, Badhiwala JH, Akbar MA, Massicotte EM, Fehlings MG.

J Clin Med. 2020 Mar 10;9(3). pii: E752. doi: 10.3390/jcm9030752.


Benefits of physical exercise on cognition and glial white matter pathology in a mouse model of vascular cognitive impairment and dementia.

Trigiani LJ, Lacalle-Aurioles M, Bourourou M, Li L, Greenhalgh AD, Zarruk JG, David S, Fehlings MG, Hamel E.

Glia. 2020 Mar 10. doi: 10.1002/glia.23815. [Epub ahead of print]


Degenerative Cervical Myelopathy: Changing Frontiers.

Moghaddamjou A, Badhiwala JH, Fehlings MG.

World Neurosurg. 2020 Mar;135:377-378. doi: 10.1016/j.wneu.2019.12.138. No abstract available.


Methylprednisolone Reduces Persistent Post-ischemic Inflammation in a Rat Hypoxia-Ischemia Model of Perinatal Stroke.

Altamentova S, Rumajogee P, Hong J, Beldick SR, Park SJ, Yee A, Fehlings MG.

Transl Stroke Res. 2020 Mar 5. doi: 10.1007/s12975-020-00792-2. [Epub ahead of print]


The Relationship Between Gastrointestinal Comorbidities, Clinical Presentation and Surgical Outcome in Patients with DCM: Analysis of a Global Cohort.

Nouri A, Badhiwala JH, Kato S, Reihani-Kermani H, Patel K, Wilson JR, Janssen I, Cheng JS, Schaller K, Tessitore E, Fehlings MG.

J Clin Med. 2020 Feb 26;9(3). pii: E624. doi: 10.3390/jcm9030624.


Machine learning algorithms for prediction of health-related quality-of-life after surgery for mild degenerative cervical myelopathy.

Khan O, Badhiwala JH, Witiw CD, Wilson JR, Fehlings MG.

Spine J. 2020 Feb 8. pii: S1529-9430(20)30047-4. doi: 10.1016/j.spinee.2020.02.003. [Epub ahead of print]


The Use of Magnetic Resonance Imaging by Spine Surgeons in Management of Spinal Trauma Across AO Regions-Results of AO Spine Survey.

Kaushal M, Shabani S, Soliman HM, Nguyen HS, Aarabi B, Fehlings MG, Kotter MR, Kwon BK, Harrop JS, Kurpad SN.

World Neurosurg. 2020 Feb 4. pii: S1878-8750(20)30218-7. doi: 10.1016/j.wneu.2020.01.200. [Epub ahead of print]


Surgical or Radiation Therapy for the Treatment of Cervical Spine Metastases: Results From the Epidemiology, Process, and Outcomes of Spine Oncology (EPOSO) Cohort.

Bond MR, Versteeg AL, Sahgal A, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Fehlings MG, Lazary A, Clarke MJ, Boriani S, Bettegowda C, Arnold PM, Gokaslan ZL, Fisher CG.

Global Spine J. 2020 Feb;10(1):21-29. doi: 10.1177/2192568219839407. Epub 2019 Mar 31.


Degenerative cervical myelopathy - update and future directions.

Badhiwala JH, Ahuja CS, Akbar MA, Witiw CD, Nassiri F, Furlan JC, Curt A, Wilson JR, Fehlings MG.

Nat Rev Neurol. 2020 Feb;16(2):108-124. doi: 10.1038/s41582-019-0303-0. Epub 2020 Jan 23. Review.


How good are the outcomes of instrumented debulking operations for symptomatic spinal metastases and how long do they stand? A subgroup analysis in the global spine tumor study group database.

Depreitere B, Ricciardi F, Arts M, Balabaud L, Bunger C, Buchowski JM, Chung CK, Coppes MH, Fehlings MG, Kawahara N, Martin-Benlloch JA, Massicotte EM, Mazel C, Meyer B, Oner FC, Peul W, Quraishi N, Tokuhashi Y, Tomita K, Verlaan JJ, Wang M, Crockard HA, Choi D.

Acta Neurochir (Wien). 2020 Apr;162(4):943-950. doi: 10.1007/s00701-019-04197-5. Epub 2020 Jan 17.


Early Surgery for Traumatic Spinal Cord Injury: Where Are We Now?

Wilson JR, Witiw CD, Badhiwala J, Kwon BK, Fehlings MG, Harrop JS.

Global Spine J. 2020 Jan;10(1 Suppl):84S-91S. doi: 10.1177/2192568219877860. Epub 2020 Jan 6.


Minimizing Blood Loss in Spine Surgery.

Mikhail C, Pennington Z, Arnold PM, Brodke DS, Chapman JR, Chutkan N, Daubs MD, DeVine JG, Fehlings MG, Gelb DE, Ghobrial GM, Harrop JS, Hoelscher C, Jiang F, Knightly JJ, Kwon BK, Mroz TE, Nassr A, Riew KD, Sekhon LH, Smith JS, Traynelis VC, Wang JC, Weber MH, Wilson JR, Witiw CD, Sciubba DM, Cho SK.

Global Spine J. 2020 Jan;10(1 Suppl):71S-83S. doi: 10.1177/2192568219868475. Epub 2020 Jan 6.


Ambulatory Surgical Centers: Improving Quality of Operative Spine Care?

Witiw CD, Wilson JR, Fehlings MG, Traynelis VC.

Global Spine J. 2020 Jan;10(1 Suppl):29S-35S. doi: 10.1177/2192568219849391. Epub 2020 Jan 6.


Quality and Safety Improvement in Spine Surgery.

Jiang F, Wilson JRF, Badhiwala JH, Santaguida C, Weber MH, Wilson JR, Fehlings MG.

Global Spine J. 2020 Jan;10(1 Suppl):17S-28S. doi: 10.1177/2192568219839699. Epub 2020 Jan 6.


The Use of Intraoperative Neurophysiological Monitoring in Spine Surgery.

Charalampidis A, Jiang F, Wilson JRF, Badhiwala JH, Brodke DS, Fehlings MG.

Global Spine J. 2020 Jan;10(1 Suppl):104S-114S. doi: 10.1177/2192568219859314. Epub 2020 Jan 6.


Cauda Equina Syndrome Core Outcome Set (CESCOS): An international patient and healthcare professional consensus for research studies.

Srikandarajah N, Noble A, Clark S, Wilby M, Freeman BJC, Fehlings MG, Williamson PR, Marson T.

PLoS One. 2020 Jan 10;15(1):e0225907. doi: 10.1371/journal.pone.0225907. eCollection 2020.


GDNF rescues the fate of neural progenitor grafts by attenuating Notch signals in the injured spinal cord in rodents.

Khazaei M, Ahuja CS, Nakashima H, Nagoshi N, Li L, Wang J, Chio J, Badner A, Seligman D, Ichise A, Shibata S, Fehlings MG.

Sci Transl Med. 2020 Jan 8;12(525). pii: eaau3538. doi: 10.1126/scitranslmed.aau3538.


Acidic Fibroblast Growth Factor in Spinal Cord Injury: A Potential Therapy Which Merits Further Investigation.

Yokota K, Fehlings MG.

Neurospine. 2019 Dec;16(4):739-741. doi: 10.14245/ns.19edi.018. Epub 2019 Dec 31. No abstract available.


Predictive Modeling of Outcomes After Traumatic and Nontraumatic Spinal Cord Injury Using Machine Learning: Review of Current Progress and Future Directions.

Khan O, Badhiwala JH, Wilson JRF, Jiang F, Martin AR, Fehlings MG.

Neurospine. 2019 Dec;16(4):678-685. doi: 10.14245/ns.1938390.195. Epub 2019 Dec 31.


Characteristics and management of pain in patients with Klippel-Feil syndrome: analysis of a global patient-reported registry.

Patel K, Evans H, Sommaruga S, Vayssiere P, Qureshi T, Kolb L, Fehlings MG, Cheng JS, Tessitore E, Schaller K, Nouri A.

J Neurosurg Spine. 2019 Dec 13:1-6. doi: 10.3171/2019.9.SPINE19820. [Epub ahead of print]


Commentary: Reliability of the New AOSpine Classification System for Upper Cervical Traumatic Injuries.

Charalampidis A, Fehlings MG.

Neurosurgery. 2020 Mar 1;86(3):E271-E272. doi: 10.1093/neuros/nyz537. No abstract available.


Characteristics of Upper Limb Impairment Related to Degenerative Cervical Myelopathy: Development of a Sensitive Hand Assessment (Graded Redefined Assessment of Strength, Sensibility, and Prehension Version Myelopathy).

Kalsi-Ryan S, Riehm LE, Tetreault L, Martin AR, Teoderascu F, Massicotte E, Curt A, Verrier MC, Velstra IM, Fehlings MG.

Neurosurgery. 2020 Mar 1;86(3):E292-E299. doi: 10.1093/neuros/nyz499.


Best practices for enhancing surgical research: a perspective from the Canadian Association of Chairs of Surgical Research

Sener A, Anderson CC, Auger FA, Barralet J, Brindle M, Cayabyab FS, Fehlings MG, Lacombe L, Perrault LP, Sabbagh R, Seely AJ, Wallace C, Ellsmere J, Keijzer R.

Can J Surg. 2019 Dec 1;62(6):488-498. doi: 10.1503/cjs.012619.


Sensory cortical control of movement.

Karadimas SK, Satkunendrarajah K, Laliberte AM, Ringuette D, Weisspapir I, Li L, Gosgnach S, Fehlings MG.

Nat Neurosci. 2020 Jan;23(1):75-84. doi: 10.1038/s41593-019-0536-7. Epub 2019 Nov 18.


Bedside Optic Nerve Ultrasonography for Diagnosing Increased Intracranial Pressure: A Systematic Review and Meta-analysis.

Koziarz A, Sne N, Kegel F, Nath S, Badhiwala JH, Nassiri F, Mansouri A, Yang K, Zhou Q, Rice T, Faidi S, Passos E, Healey A, Banfield L, Mensour M, Kirkpatrick AW, Nassar A, Fehlings MG, Hawryluk GWJ, Almenawer SA.

Ann Intern Med. 2019 Nov 19. doi: 10.7326/M19-0812. [Epub ahead of print]


Metastatic Spine Disease: Should Patients With Short Life Expectancy Be Denied Surgical Care? An International Retrospective Cohort Study.

Dea N, Versteeg AL, Sahgal A, Verlaan JJ, Charest-Morin R, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Lazary A, Fehlings MG, Clarke MJ, Arnold PM, Boriani S, Bettegowda C, Laufer I, Gokaslan ZL, Fisher CG.

Neurosurgery. 2019 Nov 6. pii: nyz472. doi: 10.1093/neuros/nyz472. [Epub ahead of print]


A combination of mesenchymal stem cells and scaffolds promotes motor functional recovery in spinal cord injury: a systematic review and meta-analysis.

Yousefifard M, Nasseri Maleki S, Askarian-Amiri S, Vaccaro AR, Chapman JR, Fehlings MG, Hosseini M, Rahimi-Movaghar V.

J Neurosurg Spine. 2019 Nov 1;32(2):269-284. doi: 10.3171/2019.8.SPINE19201. Review.


The Effect of Older Age on the Perioperative Outcomes of Spinal Fusion Surgery in Patients With Lumbar Degenerative Disc Disease With Spondylolisthesis: A Propensity Score-Matched Analysis.

Badhiwala JH, Karmur BS, Hachem LD, Wilson JRF, Jiang F, Jaja B, Nouri A, Witiw CD, Nassiri F, Fehlings MG, Wilson JR.

Neurosurgery. 2019 Oct 23. pii: nyz444. doi: 10.1093/neuros/nyz444. [Epub ahead of print]


An Age-old Debate: Anterior Versus Posterior Surgery for Ossification of the Posterior Longitudinal Ligament.

Moghaddamjou A, Fehlings MG.

Neurospine. 2019 Sep;16(3):544-547. doi: 10.14245/ns.19edi.014. Epub 2019 Sep 30. No abstract available.


Recovery priorities in degenerative cervical myelopathy: a cross-sectional survey of an international, online community of patients.

Davies B, Mowforth O, Sadler I, Aarabi B, Kwon B, Kurpad S, Harrop JS, Wilson JR, Grossman R, Fehlings MG, Kotter M.

BMJ Open. 2019 Oct 10;9(10):e031486. doi: 10.1136/bmjopen-2019-031486.


Comparison of the Inpatient Complications and Health Care Costs of Anterior versus Posterior Cervical Decompression and Fusion in Patients with Multilevel Degenerative Cervical Myelopathy: A Retrospective Propensity Score-Matched Analysis.

Badhiwala JH, Ellenbogen Y, Khan O, Nouri A, Jiang F, Wilson JRF, Jaja B, Witiw CD, Nassiri F, Fehlings MG, Wilson JR.

World Neurosurg. 2020 Feb;134:e112-e119. doi: 10.1016/j.wneu.2019.09.132. Epub 2019 Sep 28.


The graded redefined assessment of strength sensibility and prehension version 2 (GV2): Psychometric properties.

Kalsi-Ryan S, Chan C, Verrier M, Curt A, Fehlings M, Bolliger M, Velstra IM; GRASSP Cross Sectional Study Team; GRASSP Longitudinal Study Team.

J Spinal Cord Med. 2019 Oct;42(sup1):149-157. doi: 10.1080/10790268.2019.1616950.


Is there any gender or age-related discrepancy in the waiting time for each step in the surgical management of acute traumatic cervical spinal cord injury?

Furlan JC, Craven BC, Fehlings MG.

J Spinal Cord Med. 2019 Oct;42(sup1):233-241. doi: 10.1080/10790268.2019.1614291.


Sex-related discrepancies in the epidemiology, injury characteristics and outcomes after acute spine trauma: A retrospective cohort study.

Furlan JC, Craven BC, Fehlings MG.

J Spinal Cord Med. 2019 Oct;42(sup1):10-20. doi: 10.1080/10790268.2019.1607055.


The case for revisiting central cord syndrome.

Badhiwala JH, Wilson JR, Fehlings MG.

Spinal Cord. 2020 Jan;58(1):125-127. doi: 10.1038/s41393-019-0354-5. Epub 2019 Sep 13. Review. No abstract available.


Myélopathie cervicale dégénérative: Diagnostic et prise en charge en première ligne.

Milligan J, Ryan K, Fehlings M, Bauman C.

Can Fam Physician. 2019 Sep;65(9):e379-e385. Review. French.

Free PMC Article

Degenerative cervical myelopathy: Diagnosis and management in primary care.

Milligan J, Ryan K, Fehlings M, Bauman C.

Can Fam Physician. 2019 Sep;65(9):619-624. Review.


Late-differentiated effector neoantigen-specific CD8+ T cells are enriched in peripheral blood of non-small cell lung carcinoma patients responding to atezolizumab treatment.

Fehlings M, Jhunjhunwala S, Kowanetz M, O'Gorman WE, Hegde PS, Sumatoh H, Lee BH, Nardin A, Becht E, Flynn S, Ballinger M, Newell EW, Yadav M.

J Immunother Cancer. 2019 Sep 12;7(1):249. doi: 10.1186/s40425-019-0695-9.


Duration of symptoms in the quantification of upper limb disability and impairment for individuals with mild degenerative cervical myelopathy (DCM).

Kalsi-Ryan S, Clout J, Rostami P, Massicotte EM, Fehlings MG.

PLoS One. 2019 Sep 9;14(9):e0222134. doi: 10.1371/journal.pone.0222134. eCollection 2019.


Patient satisfaction with treatment outcomes after surgery and/or radiotherapy for spinal metastases.

Versteeg AL, Sahgal A, Kawahara N, Rhines LD, Sciubba DM, Weber MH, Lazary Á, Fehlings MG, Schuster JM, Clarke MJ, Arnold PM, Boriani S, Bettegowda C, Gokaslan ZL, Fisher CG; AOSpine Knowledge Forum Tumor.

Cancer. 2019 Dec 1;125(23):4269-4277. doi: 10.1002/cncr.32465. Epub 2019 Sep 6.


Degenerative Cervical Myelopathy; A Review of the Latest Advances and Future Directions in Management.

Wilson JRF, Badhiwala JH, Moghaddamjou A, Martin AR, Fehlings MG.

Neurospine. 2019 Sep;16(3):494-505. doi: 10.14245/ns.1938314.157. Epub 2019 Aug 26.


Quantification of computational geometric congruence in surface-based registration for spinal intra-operative three-dimensional navigation.

Guha D, Jakubovic R, Leung MK, Ginsberg HJ, Fehlings MG, Mainprize TG, Yee A, Yang VXD.

PLoS One. 2019 Aug 26;14(8):e0207137. doi: 10.1371/journal.pone.0207137. eCollection 2019.


The changes in systemic monocytes in humans undergoing surgical decompression for degenerative cervical myelopathy may influence clinical neurological recovery.

Vidal PM, Ulndreaj A, Tetreault L, Hong J, Fehlings MG.

J Neuroimmunol. 2019 Nov 15;336:577024. doi: 10.1016/j.jneuroim.2019.577024. Epub 2019 Aug 16.


National Spinal Cord Injury Registry of Iran (NSCIR-IR) - a critical appraisal of its strengths and weaknesses.

Sharif-Alhoseini M, Azadmanjir Z, Sadeghi-Naini M, Ghodsi Z, Naghdi K, Mohammadzadeh M, AzarHomayoun A, Zendehdel K, Khormali M, Sadeghian F, Jazayeri SB, Sehat M, Pirnejad H, Benzel EC, O'Reilly G, Fehlings MG, Vaccaro AR, Rahimi-Movaghar V.

Chin J Traumatol. 2019 Oct;22(5):300-303. doi: 10.1016/j.cjtee.2019.05.003. Epub 2019 Jul 13.


Intraoperative Error Propagation in 3-Dimensional Spinal Navigation From Nonsegmental Registration: A Prospective Cadaveric and Clinical Study.

Guha D, Jakubovic R, Gupta S, Fehlings MG, Mainprize TG, Yee A, Yang VXD.

Global Spine J. 2019 Aug;9(5):512-520. doi: 10.1177/2192568218804556. Epub 2018 Oct 9.


The Effect of Tobacco Smoking on Adverse Events Following Adult Complex Deformity Surgery: Analysis of 270 Patients From the Prospective, Multicenter Scoli-RISK-1 Study.

Wilson JRF, Jiang F, Badhiwala JH, Shaffrey CI, Carreon LY, Cheung KMC, Dahl BT, Ames CP, Boachie-Adjei O, Dekutoski MB, Lewis SJ, Matsuyama Y, Mehdian H, Pellisé F, Qiu Y, Schwab FJ, Lenke LG, Fehlings MG.

Spine (Phila Pa 1976). 2020 Jan 1;45(1):32-37. doi: 10.1097/BRS.0000000000003200.


Association of neurologic deficits with surgical outcomes and health-related quality of life after treatment for metastatic epidural spinal cord compression.

Barzilai O, Versteeg AL, Goodwin CR, Sahgal A, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Lazary A, Fehlings MG, Clarke MJ, Arnold PM, Boriani S, Bettegowda C, Gokaslan ZL, Fisher CG, Laufer I; AOSpine Knowledge Forum Tumor.

Cancer. 2019 Dec 1;125(23):4224-4231. doi: 10.1002/cncr.32420. Epub 2019 Aug 13.


Advancing spinal fellowship training: an international multi-centre educational perspective.

Kumaria A, Bateman AH, Eames N, Fehlings MG, Goldstein C, Meyer B, Paquette SJ, Yee AJM.

Eur Spine J. 2019 Nov;28(11):2437-2443. doi: 10.1007/s00586-019-06098-8. Epub 2019 Aug 12. Review.


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