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Items: 1 to 50 of 71

1.

The centrosome protein AKNA regulates neurogenesis via microtubule organization.

Camargo Ortega G, Falk S, Johansson PA, Peyre E, Broix L, Sahu SK, Hirst W, Schlichthaerle T, De Juan Romero C, Draganova K, Vinopal S, Chinnappa K, Gavranovic A, Karakaya T, Steininger T, Merl-Pham J, Feederle R, Shao W, Shi SH, Hauck SM, Jungmann R, Bradke F, Borrell V, Geerlof A, Reber S, Tiwari VK, Huttner WB, Wilsch-Bräuninger M, Nguyen L, Götz M.

Nature. 2019 Feb 20. doi: 10.1038/s41586-019-0962-4. [Epub ahead of print]

PMID:
30787442
2.

Signal Peptide Peptidase-Like 2c (SPPL2c) impairs vesicular transport and cleavage of SNARE proteins.

Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R.

EMBO Rep. 2019 Feb 7. pii: e46451. doi: 10.15252/embr.201846451. [Epub ahead of print]

PMID:
30733281
3.

The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7.

Köhler K, Sanchez-Pulido L, Höfer V, Marko A, Ponting CP, Snijders AP, Feederle R, Schepers A, Boos D.

PLoS Biol. 2019 Jan 29;17(1):e2006767. doi: 10.1371/journal.pbio.2006767. eCollection 2019 Jan.

4.

The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels.

Simons IM, Mohrlüder J, Feederle R, Kremmer E, Zobel T, Dobner J, Bleffert N, Hoffmann S, Willbold D.

Sci Rep. 2019 Jan 24;9(1):526. doi: 10.1038/s41598-018-36717-1.

5.

Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes.

Ramani A, Mariappan A, Gottardo M, Mandad S, Urlaub H, Avidor-Reiss T, Riparbelli M, Callaini G, Debec A, Feederle R, Gopalakrishnan J.

Cell Rep. 2018 Dec 26;25(13):3618-3630.e6. doi: 10.1016/j.celrep.2018.11.102.

6.

Determination of enrichment factors for modified RNA in MeRIP experiments.

Slama K, Galliot A, Weichmann F, Hertler J, Feederle R, Meister G, Helm M.

Methods. 2018 Oct 28. pii: S1046-2023(18)30304-9. doi: 10.1016/j.ymeth.2018.10.020. [Epub ahead of print]

PMID:
30394295
7.

Genomic Location of PRMT6-Dependent H3R2 Methylation Is Linked to the Transcriptional Outcome of Associated Genes.

Bouchard C, Sahu P, Meixner M, Nötzold RR, Rust MB, Kremmer E, Feederle R, Hart-Smith G, Finkernagel F, Bartkuhn M, Savai Pullamsetti S, Nist A, Stiewe T, Philipsen S, Bauer UM.

Cell Rep. 2018 Sep 18;24(12):3339-3352. doi: 10.1016/j.celrep.2018.08.052.

8.

Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers.

Frick P, Sellier C, Mackenzie IRA, Cheng CY, Tahraoui-Bories J, Martinat C, Pasterkamp RJ, Prudlo J, Edbauer D, Oulad-Abdelghani M, Feederle R, Charlet-Berguerand N, Neumann M.

Acta Neuropathol Commun. 2018 Aug 3;6(1):72. doi: 10.1186/s40478-018-0579-0.

9.

Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome.

Herber J, Njavro J, Feederle R, Schepers U, Müller UC, Bräse S, Müller SA, Lichtenthaler SF.

Mol Cell Proteomics. 2018 Aug;17(8):1487-1501. doi: 10.1074/mcp.RA118.000608. Epub 2018 May 1.

PMID:
29716987
10.

Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription.

Bütepage M, Preisinger C, von Kriegsheim A, Scheufen A, Lausberg E, Li J, Kappes F, Feederle R, Ernst S, Eckei L, Krieg S, Müller-Newen G, Rossetti G, Feijs KLH, Verheugd P, Lüscher B.

Sci Rep. 2018 Apr 30;8(1):6748. doi: 10.1038/s41598-018-25137-w.

11.

Non-cell-autonomous function of DR6 in Schwann cell proliferation.

Colombo A, Hsia HE, Wang M, Kuhn PH, Brill MS, Canevazzi P, Feederle R, Taveggia C, Misgeld T, Lichtenthaler SF.

EMBO J. 2018 Apr 3;37(7). pii: e97390. doi: 10.15252/embj.201797390. Epub 2018 Feb 19.

PMID:
29459438
12.

Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.

Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoffmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermüller J, Leonhardt H, Sharma S, Niessing D, Heissmeyer V.

Nat Commun. 2018 Jan 19;9(1):299. doi: 10.1038/s41467-017-02582-1.

13.

Interactions, localization, and phosphorylation of the m6A generating METTL3-METTL14-WTAP complex.

Schöller E, Weichmann F, Treiber T, Ringle S, Treiber N, Flatley A, Feederle R, Bruckmann A, Meister G.

RNA. 2018 Apr;24(4):499-512. doi: 10.1261/rna.064063.117. Epub 2018 Jan 18.

PMID:
29348140
14.

Double-Cone Localization and Seasonal Expression Pattern Suggest a Role in Magnetoreception for European Robin Cryptochrome 4.

Günther A, Einwich A, Sjulstok E, Feederle R, Bolte P, Koch KW, Solov'yov IA, Mouritsen H.

Curr Biol. 2018 Jan 22;28(2):211-223.e4. doi: 10.1016/j.cub.2017.12.003. Epub 2018 Jan 4.

15.

An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function.

Schlepckow K, Kleinberger G, Fukumori A, Feederle R, Lichtenthaler SF, Steiner H, Haass C.

EMBO Mol Med. 2017 Oct;9(10):1356-1365. doi: 10.15252/emmm.201707672.

16.

T cell specific Cxcr5 deficiency prevents rheumatoid arthritis.

Moschovakis GL, Bubke A, Friedrichsen M, Falk CS, Feederle R, Förster R.

Sci Rep. 2017 Aug 21;7(1):8933. doi: 10.1038/s41598-017-08935-6.

17.

Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation.

Ayoubian H, Fröhlich T, Pogodski D, Flatley A, Kremmer E, Schepers A, Feederle R, Arnold GJ, Grässer FA.

J Gen Virol. 2017 Aug;98(8):2128-2142. doi: 10.1099/jgv.0.000870. Epub 2017 Jul 28.

PMID:
28758620
18.

The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.

Kleinberger G, Brendel M, Mracsko E, Wefers B, Groeneweg L, Xiang X, Focke C, Deußing M, Suárez-Calvet M, Mazaheri F, Parhizkar S, Pettkus N, Wurst W, Feederle R, Bartenstein P, Mueggler T, Arzberger T, Knuesel I, Rominger A, Haass C.

EMBO J. 2017 Jul 3;36(13):1837-1853. doi: 10.15252/embj.201796516. Epub 2017 May 30.

19.

Poly-GP in cerebrospinal fluid links C9orf72-associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD.

Lehmer C, Oeckl P, Weishaupt JH, Volk AE, Diehl-Schmid J, Schroeter ML, Lauer M, Kornhuber J, Levin J, Fassbender K, Landwehrmeyer B; German Consortium for Frontotemporal Lobar Degeneration, Schludi MH, Arzberger T, Kremmer E, Flatley A, Feederle R, Steinacker P, Weydt P, Ludolph AC, Edbauer D, Otto M.

EMBO Mol Med. 2017 Jul;9(7):859-868. doi: 10.15252/emmm.201607486.

20.

Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins.

Zhou Q, Lehmer C, Michaelsen M, Mori K, Alterauge D, Baumjohann D, Schludi MH, Greiling J, Farny D, Flatley A, Feederle R, May S, Schreiber F, Arzberger T, Kuhm C, Klopstock T, Hermann A, Haass C, Edbauer D.

EMBO Mol Med. 2017 May;9(5):687-702. doi: 10.15252/emmm.201607054.

21.

Antibodies specific for nucleic acid modifications.

Feederle R, Schepers A.

RNA Biol. 2017 Sep 2;14(9):1089-1098. doi: 10.1080/15476286.2017.1295905. Epub 2017 Feb 23. Review.

22.

Epstein-Barr virus particles induce centrosome amplification and chromosomal instability.

Shumilov A, Tsai MH, Schlosser YT, Kratz AS, Bernhardt K, Fink S, Mizani T, Lin X, Jauch A, Mautner J, Kopp-Schneider A, Feederle R, Hoffmann I, Delecluse HJ.

Nat Commun. 2017 Feb 10;8:14257. doi: 10.1038/ncomms14257.

23.

Myb-like, SWIRM, and MPN domains 1 (MYSM1) deficiency: Genotoxic stress-associated bone marrow failure and developmental aberrations.

Bahrami E, Witzel M, Racek T, Puchałka J, Hollizeck S, Greif-Kohistani N, Kotlarz D, Horny HP, Feederle R, Schmidt H, Sherkat R, Steinemann D, Göhring G, Schlegelbeger B, Albert MH, Al-Herz W, Klein C.

J Allergy Clin Immunol. 2017 Oct;140(4):1112-1119. doi: 10.1016/j.jaci.2016.10.053. Epub 2017 Jan 21.

PMID:
28115216
24.

The biological properties of different Epstein-Barr virus strains explain their association with various types of cancers.

Tsai MH, Lin X, Shumilov A, Bernhardt K, Feederle R, Poirey R, Kopp-Schneider A, Pereira B, Almeida R, Delecluse HJ.

Oncotarget. 2017 Feb 7;8(6):10238-10254. doi: 10.18632/oncotarget.14380.

25.

Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.

Pigoni M, Wanngren J, Kuhn PH, Munro KM, Gunnersen JM, Takeshima H, Feederle R, Voytyuk I, De Strooper B, Levasseur MD, Hrupka BJ, Müller SA, Lichtenthaler SF.

Mol Neurodegener. 2016 Oct 5;11(1):67.

26.

Generation of Pax1/PAX1-Specific Monoclonal Antibodies.

Feederle R, Gerber JK, Middleton A, Northrup E, Kist R, Kremmer E, Peters H.

Monoclon Antib Immunodiagn Immunother. 2016 Oct;35(5):259-262. Epub 2016 Oct 5.

PMID:
27705080
27.

Immunological Characterization of Intraocular Lymphoid Follicles in a Spontaneous Recurrent Uveitis Model.

Kleinwort KJ, Amann B, Hauck SM, Feederle R, Sekundo W, Deeg CA.

Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4504-11. doi: 10.1167/iovs.16-19787.

PMID:
27571017
28.

TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.

Xiang X, Werner G, Bohrmann B, Liesz A, Mazaheri F, Capell A, Feederle R, Knuesel I, Kleinberger G, Haass C.

EMBO Mol Med. 2016 Sep 1;8(9):992-1004. doi: 10.15252/emmm.201606370. Print 2016 Sep.

29.

A Viral microRNA Cluster Regulates the Expression of PTEN, p27 and of a bcl-2 Homolog.

Bernhardt K, Haar J, Tsai MH, Poirey R, Feederle R, Delecluse HJ.

PLoS Pathog. 2016 Jan 22;12(1):e1005405. doi: 10.1371/journal.ppat.1005405. eCollection 2016 Jan.

30.

The Epstein-Barr Virus BART miRNA Cluster of the M81 Strain Modulates Multiple Functions in Primary B Cells.

Lin X, Tsai MH, Shumilov A, Poirey R, Bannert H, Middeldorp JM, Feederle R, Delecluse HJ.

PLoS Pathog. 2015 Dec 22;11(12):e1005344. doi: 10.1371/journal.ppat.1005344. eCollection 2015 Dec.

31.

The expression of a viral microRNA is regulated by clustering to allow optimal B cell transformation.

Haar J, Contrant M, Bernhardt K, Feederle R, Diederichs S, Pfeffer S, Delecluse HJ.

Nucleic Acids Res. 2016 Feb 18;44(3):1326-41. doi: 10.1093/nar/gkv1330. Epub 2015 Dec 3.

32.

Epstein-Barr Virus: From the Detection of Sequence Polymorphisms to the Recognition of Viral Types.

Feederle R, Klinke O, Kutikhin A, Poirey R, Tsai MH, Delecluse HJ.

Curr Top Microbiol Immunol. 2015;390(Pt 1):119-48. doi: 10.1007/978-3-319-22822-8_7. Review.

PMID:
26424646
33.

KIT Mutation and Loss of 14q May Be Sufficient for the Development of Clinically Symptomatic Very Low-Risk GIST.

Klinke OK, Mizani T, Baldwin G, Bancel B, Devouassoux-Shisheboran M, Scoazec JY, Bringuier PP, Feederle R, Jauch A, Hinderhofer K, Taniere P, Delecluse HJ.

PLoS One. 2015 Jun 23;10(6):e0130149. doi: 10.1371/journal.pone.0130149. eCollection 2015.

34.

Antigen-armed antibodies targeting B lymphoma cells effectively activate antigen-specific CD4+ T cells.

Yu X, Ilecka M, Bartlett EJ, Schneidt V, Bhat R, Mautner J, Feederle R, Delecluse HJ.

Blood. 2015 Mar 5;125(10):1601-10. doi: 10.1182/blood-2014-07-591412. Epub 2015 Jan 7.

35.

Genetics of Epstein-Barr virus microRNAs.

Klinke O, Feederle R, Delecluse HJ.

Semin Cancer Biol. 2014 Jun;26:52-9. doi: 10.1016/j.semcancer.2014.02.002. Epub 2014 Mar 3. Review.

PMID:
24602823
36.

Human natural killer cells prevent infectious mononucleosis features by targeting lytic Epstein-Barr virus infection.

Chijioke O, Müller A, Feederle R, Barros MH, Krieg C, Emmel V, Marcenaro E, Leung CS, Antsiferova O, Landtwing V, Bossart W, Moretta A, Hassan R, Boyman O, Niedobitek G, Delecluse HJ, Capaul R, Münz C.

Cell Rep. 2013 Dec 26;5(6):1489-98. doi: 10.1016/j.celrep.2013.11.041. Epub 2013 Dec 19. Erratum in: Cell Rep. 2015 Aug 4;12(5):901.

37.

Spontaneous lytic replication and epitheliotropism define an Epstein-Barr virus strain found in carcinomas.

Tsai MH, Raykova A, Klinke O, Bernhardt K, Gärtner K, Leung CS, Geletneky K, Sertel S, Münz C, Feederle R, Delecluse HJ.

Cell Rep. 2013 Oct 31;5(2):458-70. doi: 10.1016/j.celrep.2013.09.012. Epub 2013 Oct 10.

38.

An Epstein-Barr virus mutant produces immunogenic defective particles devoid of viral DNA.

Pavlova S, Feederle R, Gärtner K, Fuchs W, Granzow H, Delecluse HJ.

J Virol. 2013 Feb;87(4):2011-22. doi: 10.1128/JVI.02533-12. Epub 2012 Dec 12.

39.

Epstein-Barr virus infection of naïve B cells in vitro frequently selects clones with mutated immunoglobulin genotypes: implications for virus biology.

Heath E, Begue-Pastor N, Chaganti S, Croom-Carter D, Shannon-Lowe C, Kube D, Feederle R, Delecluse HJ, Rickinson AB, Bell AI.

PLoS Pathog. 2012;8(5):e1002697. doi: 10.1371/journal.ppat.1002697. Epub 2012 May 10.

40.

The viral and cellular microRNA targetome in lymphoblastoid cell lines.

Skalsky RL, Corcoran DL, Gottwein E, Frank CL, Kang D, Hafner M, Nusbaum JD, Feederle R, Delecluse HJ, Luftig MA, Tuschl T, Ohler U, Cullen BR.

PLoS Pathog. 2012 Jan;8(1):e1002484. doi: 10.1371/journal.ppat.1002484. Epub 2012 Jan 26.

41.

The members of an Epstein-Barr virus microRNA cluster cooperate to transform B lymphocytes.

Feederle R, Haar J, Bernhardt K, Linnstaedt SD, Bannert H, Lips H, Cullen BR, Delecluse HJ.

J Virol. 2011 Oct;85(19):9801-10. doi: 10.1128/JVI.05100-11. Epub 2011 Jul 13.

42.

A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus.

Feederle R, Linnstaedt SD, Bannert H, Lips H, Bencun M, Cullen BR, Delecluse HJ.

PLoS Pathog. 2011 Feb;7(2):e1001294. doi: 10.1371/journal.ppat.1001294. Epub 2011 Feb 17.

43.

The Epstein-Barr virus-encoded BILF1 protein modulates immune recognition of endogenously processed antigen by targeting major histocompatibility complex class I molecules trafficking on both the exocytic and endocytic pathways.

Zuo J, Quinn LL, Tamblyn J, Thomas WA, Feederle R, Delecluse HJ, Hislop AD, Rowe M.

J Virol. 2011 Feb;85(4):1604-14. doi: 10.1128/JVI.01608-10. Epub 2010 Dec 1.

44.

Epstein-Barr virus genetics: talking about the BAC generation.

Feederle R, Bartlett EJ, Delecluse HJ.

Herpesviridae. 2010 Dec 7;1(1):6. doi: 10.1186/2042-4280-1-6.

45.

Epstein-Barr viruses that express a CD21 antibody provide evidence that gp350's functions extend beyond B-cell surface binding.

Busse C, Feederle R, Schnölzer M, Behrends U, Mautner J, Delecluse HJ.

J Virol. 2010 Jan;84(2):1139-47. doi: 10.1128/JVI.01953-09. Epub 2009 Nov 4.

46.

The Epstein-Barr virus protein kinase BGLF4 and the exonuclease BGLF5 have opposite effects on the regulation of viral protein production.

Feederle R, Mehl-Lautscham AM, Bannert H, Delecluse HJ.

J Virol. 2009 Nov;83(21):10877-91. doi: 10.1128/JVI.00525-09. Epub 2009 Aug 26.

47.

Expression and processing of a small nucleolar RNA from the Epstein-Barr virus genome.

Hutzinger R, Feederle R, Mrazek J, Schiefermeier N, Balwierz PJ, Zavolan M, Polacek N, Delecluse HJ, Hüttenhofer A.

PLoS Pathog. 2009 Aug;5(8):e1000547. doi: 10.1371/journal.ppat.1000547. Epub 2009 Aug 14.

48.

Oncolytic rat parvovirus H-1PV, a candidate for the treatment of human lymphoma: In vitro and in vivo studies.

Angelova AL, Aprahamian M, Balboni G, Delecluse HJ, Feederle R, Kiprianova I, Grekova SP, Galabov AS, Witzens-Harig M, Ho AD, Rommelaere J, Raykov Z.

Mol Ther. 2009 Jul;17(7):1164-72. doi: 10.1038/mt.2009.78. Epub 2009 Apr 14.

49.

The Epstein-Barr virus alkaline exonuclease BGLF5 serves pleiotropic functions in virus replication.

Feederle R, Bannert H, Lips H, Müller-Lantzsch N, Delecluse HJ.

J Virol. 2009 May;83(10):4952-62. doi: 10.1128/JVI.00170-09. Epub 2009 Mar 4.

50.

Primary B-cell infection with a deltaBALF4 Epstein-Barr virus comes to a halt in the endosomal compartment yet still elicits a potent CD4-positive cytotoxic T-cell response.

Neuhierl B, Feederle R, Adhikary D, Hub B, Geletneky K, Mautner J, Delecluse HJ.

J Virol. 2009 May;83(9):4616-23. doi: 10.1128/JVI.01613-08. Epub 2009 Feb 25.

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