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Items: 36

1.

Multiple blood-brain barrier transport mechanisms limit bumetanide accumulation, and therapeutic potential, in the mammalian brain.

Römermann K, Fedrowitz M, Hampel P, Kaczmarek E, Töllner K, Erker T, Sweet DH, Löscher W.

Neuropharmacology. 2017 May 1;117:182-194. doi: 10.1016/j.neuropharm.2017.02.006. Epub 2017 Feb 10.

PMID:
28192112
2.

Comparative dosimetry for children and rodents exposed to extremely low-frequency magnetic fields.

Gong Y, Capstick M, Dasenbrock C, Fedrowitz M, Cobaleda C, Sánchez-García I, Kuster N.

Bioelectromagnetics. 2016 Jul;37(5):310-22. doi: 10.1002/bem.21976. Epub 2016 May 13.

PMID:
27176719
3.

Extremely low-frequency magnetic fields and risk of childhood leukemia: A risk assessment by the ARIMMORA consortium.

Schüz J, Dasenbrock C, Ravazzani P, Röösli M, Schär P, Bounds PL, Erdmann F, Borkhardt A, Cobaleda C, Fedrowitz M, Hamnerius Y, Sanchez-Garcia I, Seger R, Schmiegelow K, Ziegelberger G, Capstick M, Manser M, Müller M, Schmid CD, Schürmann D, Struchen B, Kuster N.

Bioelectromagnetics. 2016 Apr;37(3):183-189. doi: 10.1002/bem.21963. Epub 2016 Mar 15.

PMID:
26991812
4.

Marked differences in the effect of antiepileptic and cytostatic drugs on the functionality of P-glycoprotein in human and rat brain capillary endothelial cell lines.

Alms D, Fedrowitz M, Römermann K, Noack A, Löscher W.

Pharm Res. 2014 Jun;31(6):1588-604. doi: 10.1007/s11095-013-1264-4. Epub 2014 Jan 30.

PMID:
24477677
5.

(R)-[(11)C]verapamil is selectively transported by murine and human P-glycoprotein at the blood-brain barrier, and not by MRP1 and BCRP.

Römermann K, Wanek T, Bankstahl M, Bankstahl JP, Fedrowitz M, Müller M, Löscher W, Kuntner C, Langer O.

Nucl Med Biol. 2013 Oct;40(7):873-8. doi: 10.1016/j.nucmedbio.2013.05.012. Epub 2013 Jul 8.

6.

Tariquidar and elacridar are dose-dependently transported by P-glycoprotein and Bcrp at the blood-brain barrier: a small-animal positron emission tomography and in vitro study.

Bankstahl JP, Bankstahl M, Römermann K, Wanek T, Stanek J, Windhorst AD, Fedrowitz M, Erker T, Müller M, Löscher W, Langer O, Kuntner C.

Drug Metab Dispos. 2013 Apr;41(4):754-62. doi: 10.1124/dmd.112.049148. Epub 2013 Jan 10.

PMID:
23305710
7.

Effects of 50 Hz magnetic field exposure on the stress marker α-amylase in the rat mammary gland.

Fedrowitz M, Hass R, Löscher W.

Int J Radiat Biol. 2012 Jul;88(7):556-64. doi: 10.3109/09553002.2012.691614.

PMID:
22563858
8.

Gene expression in the mammary gland tissue of female Fischer 344 and Lewis rats after magnetic field exposure (50 Hz, 100 μT) for 2 weeks.

Fedrowitz M, Löscher W.

Int J Radiat Biol. 2012 May;88(5):425-9. doi: 10.3109/09553002.2012.660555. Epub 2012 Feb 28.

PMID:
22280403
9.

Salivary α-amylase exhibits antiproliferative effects in primary cell cultures of rat mammary epithelial cells and human breast cancer cells.

Fedrowitz M, Hass R, Bertram C, Löscher W.

J Exp Clin Cancer Res. 2011;30:102. doi: 10.1186/1756-9966-30-102. Epub 2011 Oct 25.

10.

Do ATP-binding cassette transporters cause pharmacoresistance in epilepsy? Problems and approaches in determining which antiepileptic drugs are affected.

Löscher W, Luna-Tortós C, Römermann K, Fedrowitz M.

Curr Pharm Des. 2011;17(26):2808-28. Review.

PMID:
21827408
11.

Impact of seizure activity on free extracellular phenytoin concentrations in amygdala-kindled rats.

Potschka H, Baltes S, Fedrowitz M, Löscher W.

Neuropharmacology. 2011 Oct-Nov;61(5-6):909-17. doi: 10.1016/j.neuropharm.2011.06.018. Epub 2011 Jun 29.

PMID:
21736886
12.

Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy.

Luna-Tortós C, Fedrowitz M, Löscher W.

Neuropharmacology. 2010 Jun;58(7):1019-32. doi: 10.1016/j.neuropharm.2010.01.007. Epub 2010 Jan 18.

PMID:
20080116
13.

Exposure to antiepileptic drugs does not alter the functionality of P-glycoprotein in brain capillary endothelial and kidney cell lines.

Ambroziak K, Kuteykin-Teplyakov K, Luna-Tórtos C, Al-Falah M, Fedrowitz M, Löscher W.

Eur J Pharmacol. 2010 Feb 25;628(1-3):57-66. doi: 10.1016/j.ejphar.2009.11.051. Epub 2009 Dec 1.

PMID:
19958760
14.

Several major antiepileptic drugs are substrates for human P-glycoprotein.

Luna-Tortós C, Fedrowitz M, Löscher W.

Neuropharmacology. 2008 Dec;55(8):1364-75. doi: 10.1016/j.neuropharm.2008.08.032. Epub 2008 Sep 11.

PMID:
18824002
15.
16.

Prophylactic treatment with levetiracetam after status epilepticus: lack of effect on epileptogenesis, neuronal damage, and behavioral alterations in rats.

Brandt C, Glien M, Gastens AM, Fedrowitz M, Bethmann K, Volk HA, Potschka H, Löscher W.

Neuropharmacology. 2007 Aug;53(2):207-21. Epub 2007 May 18.

PMID:
17585956
17.

Auditory and vestibular defects and behavioral alterations after neonatal administration of streptomycin to Lewis rats: Similarities and differences to the circling (ci2/ci2) Lewis rat mutant.

Schirmer M, Kaiser A, Lessenich A, Lindemann S, Fedrowitz M, Gernert M, Löscher W.

Brain Res. 2007 Jun 25;1155:179-95. Epub 2007 Apr 11.

PMID:
17493596
18.

Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein.

Baltes S, Gastens AM, Fedrowitz M, Potschka H, Kaever V, Löscher W.

Neuropharmacology. 2007 Feb;52(2):333-46. Epub 2006 Oct 10.

PMID:
17045309
19.

Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays.

Baltes S, Fedrowitz M, Tortós CL, Potschka H, Löscher W.

J Pharmacol Exp Ther. 2007 Jan;320(1):331-43. Epub 2006 Oct 16.

PMID:
17043155
21.

Incidence of post-anaesthetic arrhythmias in dogs.

Buhl K, Kersten U, Kramer S, Mischke R, Fedrowitz M, Nolte I.

J Small Anim Pract. 2005 Mar;46(3):131-8.

PMID:
15789808
22.
24.

[Comparison of the influence of different anesthetic protocols in the development of post-anesthetic arrhythmia in the dog].

Buhl K, Kersten U, Kramer S, Mischke R, Fedrowitz M, Nolte I.

Dtsch Tierarztl Wochenschr. 2003 Oct;110(10):407-12. German.

PMID:
14650735
25.
26.

Altered spontaneous discharge rate and pattern of basal ganglia output neurons in the circling (ci2) rat mutant.

Fedrowitz M, Lindemann S, Löscher W, Gernert M.

Neuroscience. 2003;118(3):867-78.

PMID:
12710993
27.

Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity.

Potschka H, Fedrowitz M, Löscher W.

J Pharmacol Exp Ther. 2003 Jul;306(1):124-31. Epub 2003 Mar 27.

PMID:
12663688
28.

Altered discharge pattern of basal ganglia output neurons in an animal model of idiopathic dystonia.

Gernert M, Bennay M, Fedrowitz M, Rehders JH, Richter A.

J Neurosci. 2002 Aug 15;22(16):7244-53.

29.
30.

Effects of locally administered pentylenetetrazole on nigral single unit activity and severity of dystonia in a genetic model of paroxysmal dystonia.

Fedrowitz M, Hamann M, Rehders JH, Richter A, Gernert M.

J Neurosci Res. 2002 Jun 1;68(5):595-603.

PMID:
12111849
31.
33.

Auditory and vestibular defects in the circling (ci2) rat mutant.

Kaiser A, Fedrowitz M, Ebert U, Zimmermann E, Hedrich HJ, Wedekind D, Löscher W.

Eur J Neurosci. 2001 Oct;14(7):1129-42.

PMID:
11683905
34.
36.

Immunohistochemical and neurochemical studies on nigral and striatal functions in the circling (ci) rat, a genetic animal model with spontaneous rotational behavior.

Richter A, Ebert U, Nobrega JN, Vallbacka JJ, Fedrowitz M, Löscher W.

Neuroscience. 1999 Mar;89(2):461-71.

PMID:
10077328

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