Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 143

1.

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.

Fagan V, Johansson C, Gileadi C, Monteiro O, Dunford JE, Nibhani R, Philpott M, Malzahn J, Wells G, Faram R, Cribbs AP, Halidi N, Li F, Chau I, Greschik H, Velupillai S, Allali-Hassani A, Bennett J, Christott T, Giroud C, Lewis AM, Huber KVM, Athanasou N, Bountra C, Jung M, Schüle R, Vedadi M, Arrowsmith C, Xiong Y, Jin J, Fedorov O, Farnie G, Brennan PE, Oppermann U.

J Med Chem. 2019 Oct 24;62(20):9008-9025. doi: 10.1021/acs.jmedchem.9b00562. Epub 2019 Oct 15.

PMID:
31550156
2.

Light-Mediated Dual Phosphine-/Copper-Catalyzed Atom Transfer Radical Addition Reaction.

Fedorov OV, Scherbinina SI, Levin VV, Dilman AD.

J Org Chem. 2019 Sep 6;84(17):11068-11079. doi: 10.1021/acs.joc.9b01649. Epub 2019 Aug 26.

PMID:
31409063
3.

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3.

Böttcher J, Dilworth D, Reiser U, Neumüller RA, Schleicher M, Petronczki M, Zeeb M, Mischerikow N, Allali-Hassani A, Szewczyk MM, Li F, Kennedy S, Vedadi M, Barsyte-Lovejoy D, Brown PJ, Huber KVM, Rogers CM, Wells CI, Fedorov O, Rumpel K, Zoephel A, Mayer M, Wunberg T, Böse D, Zahn S, Arnhof H, Berger H, Reiser C, Hörmann A, Krammer T, Corcokovic M, Sharps B, Winkler S, Häring D, Cockcroft XL, Fuchs JE, Müllauer B, Weiss-Puxbaum A, Gerstberger T, Boehmelt G, Vakoc CR, Arrowsmith CH, Pearson M, McConnell DB.

Nat Chem Biol. 2019 Aug;15(8):822-829. doi: 10.1038/s41589-019-0310-x. Epub 2019 Jul 8.

PMID:
31285596
4.

Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).

Xiong Y, Greschik H, Johansson C, Seifert L, Bacher J, Park KS, Babault N, Martini M, Fagan V, Li F, Chau I, Christott T, Dilworth D, Barsyte-Lovejoy D, Vedadi M, Arrowsmith CH, Brennan P, Fedorov O, Jung M, Farnie G, Liu J, Oppermann U, Schüle R, Jin J.

J Med Chem. 2019 Oct 24;62(20):8996-9007. doi: 10.1021/acs.jmedchem.9b00522. Epub 2019 Jul 24.

PMID:
31260300
5.

C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays.

Le Bihan YV, Lanigan RM, Atrash B, McLaughlin MG, Velupillai S, Malcolm AG, England KS, Ruda GF, Mok NY, Tumber A, Tomlin K, Saville H, Shehu E, McAndrew C, Carmichael L, Bennett JM, Jeganathan F, Eve P, Donovan A, Hayes A, Wood F, Raynaud FI, Fedorov O, Brennan PE, Burke R, van Montfort RLM, Rossanese OW, Blagg J, Bavetsias V.

Eur J Med Chem. 2019 Sep 1;177:316-337. doi: 10.1016/j.ejmech.2019.05.041. Epub 2019 May 17.

6.

Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening.

Resnick E, Bradley A, Gan J, Douangamath A, Krojer T, Sethi R, Geurink PP, Aimon A, Amitai G, Bellini D, Bennett J, Fairhead M, Fedorov O, Gabizon R, Gan J, Guo J, Plotnikov A, Reznik N, Ruda GF, Díaz-Sáez L, Straub VM, Szommer T, Velupillai S, Zaidman D, Zhang Y, Coker AR, Dowson CG, Barr HM, Wang C, Huber KVM, Brennan PE, Ovaa H, von Delft F, London N.

J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.

7.

A chemical toolbox for the study of bromodomains and epigenetic signaling.

Wu Q, Heidenreich D, Zhou S, Ackloo S, Krämer A, Nakka K, Lima-Fernandes E, Deblois G, Duan S, Vellanki RN, Li F, Vedadi M, Dilworth J, Lupien M, Brennan PE, Arrowsmith CH, Müller S, Fedorov O, Filippakopoulos P, Knapp S.

Nat Commun. 2019 Apr 23;10(1):1915. doi: 10.1038/s41467-019-09672-2.

8.

SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK).

Asquith CRM, Berger BT, Wan J, Bennett JM, Capuzzi SJ, Crona DJ, Drewry DH, East MP, Elkins JM, Fedorov O, Godoi PH, Hunter DM, Knapp S, Müller S, Torrice CD, Wells CI, Earp HS, Willson TM, Zuercher WJ.

J Med Chem. 2019 Mar 14;62(5):2830-2836. doi: 10.1021/acs.jmedchem.8b01213. Epub 2019 Feb 26.

9.

WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop.

Agajanian MJ, Walker MP, Axtman AD, Ruela-de-Sousa RR, Serafin DS, Rabinowitz AD, Graham DM, Ryan MB, Tamir T, Nakamichi Y, Gammons MV, Bennett JM, Couñago RM, Drewry DH, Elkins JM, Gileadi C, Gileadi O, Godoi PH, Kapadia N, Müller S, Santiago AS, Sorrell FJ, Wells CI, Fedorov O, Willson TM, Zuercher WJ, Major MB.

Cell Rep. 2019 Jan 2;26(1):79-93.e8. doi: 10.1016/j.celrep.2018.12.023.

10.

An Activity-Based Probe Targeting Non-Catalytic, Highly Conserved Amino Acid Residues within Bromodomains.

D'Ascenzio M, Pugh KM, Konietzny R, Berridge G, Tallant C, Hashem S, Monteiro O, Thomas JR, Schirle M, Knapp S, Marsden B, Fedorov O, Bountra C, Kessler BM, Brennan PE.

Angew Chem Int Ed Engl. 2019 Jan 21;58(4):1007-1012. doi: 10.1002/anie.201807825. Epub 2018 Dec 27.

11.

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.

Vazquez-Rodriguez S, Wright M, Rogers CM, Cribbs AP, Velupillai S, Philpott M, Lee H, Dunford JE, Huber KVM, Robers MB, Vasta JD, Thezenas ML, Bonham S, Kessler B, Bennett J, Fedorov O, Raynaud F, Donovan A, Blagg J, Bavetsias V, Oppermann U, Bountra C, Kawamura A, Brennan PE.

Angew Chem Int Ed Engl. 2019 Jan 8;58(2):515-519. doi: 10.1002/anie.201810179. Epub 2018 Dec 7.

12.

Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL).

Heidenreich D, Moustakim M, Schmidt J, Merk D, Brennan PE, Fedorov O, Chaikuad A, Knapp S.

J Med Chem. 2018 Dec 13;61(23):10929-10934. doi: 10.1021/acs.jmedchem.8b01457. Epub 2018 Nov 26.

PMID:
30407816
13.

Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9.

Christott T, Bennett J, Coxon C, Monteiro O, Giroud C, Beke V, Felce SL, Gamble V, Gileadi C, Poda G, Al-Awar R, Farnie G, Fedorov O.

SLAS Discov. 2019 Feb;24(2):133-141. doi: 10.1177/2472555218809904. Epub 2018 Oct 25.

PMID:
30359161
14.

Discovery of an MLLT1/3 YEATS Domain Chemical Probe.

Moustakim M, Christott T, Monteiro OP, Bennett J, Giroud C, Ward J, Rogers CM, Smith P, Panagakou I, Díaz-Sáez L, Felce SL, Gamble V, Gileadi C, Halidi N, Heidenreich D, Chaikuad A, Knapp S, Huber KVM, Farnie G, Heer J, Manevski N, Poda G, Al-Awar R, Dixon DJ, Brennan PE, Fedorov O.

Angew Chem Int Ed Engl. 2018 Dec 10;57(50):16302-16307. doi: 10.1002/anie.201810617. Epub 2018 Nov 16.

15.

Salt-dependent regulation of archaellins in Haloarcula marismortui.

Syutkin AS, van Wolferen M, Surin AK, Albers SV, Pyatibratov MG, Fedorov OV, Quax TEF.

Microbiologyopen. 2019 May;8(5):e00718. doi: 10.1002/mbo3.718. Epub 2018 Oct 1.

16.

Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains.

Wang J, Erazo T, Ferguson FM, Buckley DL, Gomez N, Muñoz-Guardiola P, Diéguez-Martínez N, Deng X, Hao M, Massefski W, Fedorov O, Offei-Addo NK, Park PM, Dai L, DiBona A, Becht K, Kim ND, McKeown MR, Roberts JM, Zhang J, Sim T, Alessi DR, Bradner JE, Lizcano JM, Blacklow SC, Qi J, Xu X, Gray NS.

ACS Chem Biol. 2018 Sep 21;13(9):2438-2448. doi: 10.1021/acschembio.7b00638. Epub 2018 Aug 31.

17.

Precision Study of η^{'}→γπ^{+}π^{-} Decay Dynamics.

Ablikim M, Achasov MN, Ahmed S, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Ferroli RB, Ban Y, Bennett DW, Bennett JV, Berger N, Bertani M, Bettoni D, Bian JM, Bianchi F, Boger E, Boyko I, Briere RA, Cai H, Cai X, Cakir O, Calcaterra A, Cao GF, Cetin SA, Chai J, Chang JF, Chelkov G, Chen G, Chen HS, Chen JC, Chen ML, Chen S, Chen SJ, Chen X, Chen XR, Chen YB, Cheng HP, Chu XK, Cibinetto G, Dai HL, Dai JP, Dbeyssi A, Dedovich D, Deng ZY, Denig A, Denysenko I, Destefanis M, De Mori F, Ding Y, Dong C, Dong J, Dong LY, Dong MY, Dou ZL, Du SX, Duan PF, Fan JZ, Fang J, Fang SS, Fang X, Fang Y, Farinelli R, Fava L, Fedorov O, Fegan S, Feldbauer F, Felici G, Feng CQ, Fioravanti E, Fritsch M, Fu CD, Gao Q, Gao XL, Gao Y, Gao Z, Garzia I, Goetzen K, Gong L, Gong WX, Gradl W, Greco M, Gu MH, Gu YT, Guan YH, Guo AQ, Guo LB, Guo RP, Guo Y, Guo YP, Haddadi Z, Hafner A, Han S, Hao XQ, Harris FA, He KL, Heinsius FH, Held T, Heng YK, Holtmann T, Hou ZL, Hu C, Hu HM, Hu JF, Hu T, Hu Y, Huang GS, Huang JS, Huang XT, Huang XZ, Huang Y, Huang ZL, Hussain T, Ji Q, Ji QP, Ji XB, Ji XL, Jiang LW, Jiang XS, Jiang XY, Jiao JB, Jiao Z, Jin DP, Jin S, Johansson T, Julin A, Kalantar-Nayestanaki N, Kang XL, Kang XS, Kavatsyuk M, Ke BC, Kiese P, Kliemt R, Kloss B, Kolcu OB, Kopf B, Kornicer M, Kupsc A, Kühn W, Lange JS, Lara M, Larin P, Leithoff H, Leng C, Li C, Li C, Li DM, Li F, Li FY, Li G, Li HB, Li HJ, Li JC, Li J, Li K, Li K, Li L, Li PR, Li QY, Li T, Li WD, Li WG, Li XL, Li XN, Li XQ, Li YB, Li ZB, Liang H, Liang YF, Liang YT, Liao GR, Lin DX, Liu B, Liu BJ, Liu CX, Liu D, Liu FH, Liu F, Liu F, Liu HB, Liu HH, Liu HH, Liu HM, Liu J, Liu JB, Liu JP, Liu JY, Liu K, Liu KY, Liu LD, Liu PL, Liu Q, Liu SB, Liu X, Liu YB, Liu YY, Liu ZA, Liu Z, Loehner H, Long YF, Lou XC, Lu HJ, Lu JG, Lu Y, Lu YP, Luo CL, Luo MX, Luo T, Luo XL, Lyu XR, Ma FC, Ma HL, Ma LL, Ma MM, Ma QM, Ma T, Ma XN, Ma XY, Ma YM, Maas FE, Maggiora M, Malik QA, Mao YJ, Mao ZP, Marcello S, Messchendorp JG, Mezzadri G, Min J, Min TJ, Mitchell RE, Mo XH, Mo YJ, Morales CM, Muchnoi NY, Muramatsu H, Musiol P, Nefedov Y, Nerling F, Nikolaev IB, Ning Z, Nisar S, Niu SL, Niu XY, Olsen SL, Ouyang Q, Pacetti S, Pan Y, Patteri P, Pelizaeus M, Peng HP, Peters K, Pettersson J, Ping JL, Ping RG, Poling R, Prasad V, Qi HR, Qi M, Qian S, Qiao CF, Qin LQ, Qin N, Qin XS, Qin ZH, Qiu JF, Rashid KH, Redmer CF, Ripka M, Rong G, Rosner C, Ruan XD, Sarantsev A, Savrié M, Schnier C, Schoenning K, Schumann S, Shan W, Shao M, Shen CP, Shen PX, Shen XY, Sheng HY, Shi M, Song WM, Song XY, Sosio S, Spataro S, Sun GX, Sun JF, Sun SS, Sun XH, Sun YJ, Sun YZ, Sun ZJ, Sun ZT, Tang CJ, Tang X, Tapan I, Thorndike EH, Tiemens M, Uman I, Varner GS, Wang B, Wang BL, Wang D, Wang DY, Wang K, Wang LL, Wang LS, Wang M, Wang P, Wang PL, Wang W, Wang WP, Wang XF, Wang Y, Wang YD, Wang YF, Wang YQ, Wang Z, Wang ZG, Wang ZH, Wang ZY, Wang ZY, Weber T, Wei DH, Weidenkaff P, Wen SP, Wiedner U, Wolke M, Wu LH, Wu LJ, Wu Z, Xia L, Xia LG, Xia Y, Xiao D, Xiao H, Xiao ZJ, Xie YG, Xiu QL, Xu GF, Xu JJ, Xu L, Xu QJ, Xu QN, Xu XP, Yan L, Yan WB, Yan WC, Yan YH, Yang HJ, Yang HX, Yang L, Yang YX, Ye M, Ye MH, Yin JH, You ZY, Yu BX, Yu CX, Yu JS, Yuan CZ, Yuan WL, Yuan Y, Yuncu A, Zafar AA, Zallo A, Zeng Y, Zeng Z, Zhang BX, Zhang BY, Zhang C, Zhang CC, Zhang DH, Zhang HH, Zhang HY, Zhang J, Zhang JJ, Zhang JL, Zhang JQ, Zhang JW, Zhang JY, Zhang JZ, Zhang K, Zhang L, Zhang SQ, Zhang XY, Zhang Y, Zhang Y, Zhang YH, Zhang YN, Zhang YT, Zhang Y, Zhang ZH, Zhang ZP, Zhang ZY, Zhao G, Zhao JW, Zhao JY, Zhao JZ, Zhao L, Zhao L, Zhao MG, Zhao Q, Zhao QW, Zhao SJ, Zhao TC, Zhao YB, Zhao ZG, Zhemchugov A, Zheng B, Zheng JP, Zheng WJ, Zheng YH, Zhong B, Zhou L, Zhou X, Zhou XK, Zhou XR, Zhou XY, Zhu K, Zhu KJ, Zhu S, Zhu SH, Zhu XL, Zhu YC, Zhu YS, Zhu ZA, Zhuang J, Zotti L, Zou BS, Zou JH; BESIII Collaboration.

Phys Rev Lett. 2018 Jun 15;120(24):242003. doi: 10.1103/PhysRevLett.120.242003.

18.

Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2.

Moustakim M, Riedel K, Schuller M, Gehring AP, Monteiro OP, Martin SP, Fedorov O, Heer J, Dixon DJ, Elkins JM, Knapp S, Bracher F, Brennan PE.

Bioorg Med Chem. 2018 Jul 15;26(11):2965-2972. doi: 10.1016/j.bmc.2018.03.020. Epub 2018 Mar 12.

19.

Archaeal Flagella as Biotemplates for Nanomaterials with New Properties.

Beznosov SN, Pyatibratov MG, Fedorov OV.

Biochemistry (Mosc). 2018 Jan;83(Suppl 1):S56-S61. doi: 10.1134/S0006297918140067. Review.

20.

Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design.

Rahm F, Viklund J, Trésaugues L, Ellermann M, Giese A, Ericsson U, Forsblom R, Ginman T, Günther J, Hallberg K, Lindström J, Persson LB, Silvander C, Talagas A, Díaz-Sáez L, Fedorov O, Huber KVM, Panagakou I, Siejka P, Gorjánácz M, Bauser M, Andersson M.

J Med Chem. 2018 Mar 22;61(6):2533-2551. doi: 10.1021/acs.jmedchem.7b01884. Epub 2018 Mar 7.

PMID:
29485874
21.

Tryptophan-Mediated Interactions between Tristetraprolin and the CNOT9 Subunit Are Required for CCR4-NOT Deadenylase Complex Recruitment.

Bulbrook D, Brazier H, Mahajan P, Kliszczak M, Fedorov O, Marchese FP, Aubareda A, Chalk R, Picaud S, Strain-Damerell C, Filippakopoulos P, Gileadi O, Clark AR, Yue WW, Burgess-Brown NA, Dean JLE.

J Mol Biol. 2018 Mar 2;430(5):722-736. doi: 10.1016/j.jmb.2017.12.018. Epub 2017 Dec 29.

PMID:
29291391
22.

Correction: Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety.

Sansook S, Ocasio CA, Day IJ, Tizzard GJ, Coles SJ, Fedorov O, Bennett JM, Elkins JM, Spencer J.

Org Biomol Chem. 2018 Jan 3;16(2):336. doi: 10.1039/c7ob90195j.

PMID:
29256564
23.

Synthesis of 3-Fluoropyridines via Photoredox-Mediated Coupling of α,α-Difluoro-β-iodoketones with Silyl Enol Ethers.

Scherbinina SI, Fedorov OV, Levin VV, Kokorekin VA, Struchkova MI, Dilman AD.

J Org Chem. 2017 Dec 15;82(24):12967-12974. doi: 10.1021/acs.joc.7b02467. Epub 2017 Nov 30.

24.

Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action.

Fernández-Montalván AE, Berger M, Kuropka B, Koo SJ, Badock V, Weiske J, Puetter V, Holton SJ, Stöckigt D, Ter Laak A, Centrella PA, Clark MA, Dumelin CE, Sigel EA, Soutter HH, Troast DM, Zhang Y, Cuozzo JW, Keefe AD, Roche D, Rodeschini V, Chaikuad A, Díaz-Sáez L, Bennett JM, Fedorov O, Huber KVM, Hübner J, Weinmann H, Hartung IV, Gorjánácz M.

ACS Chem Biol. 2017 Nov 17;12(11):2730-2736. doi: 10.1021/acschembio.7b00708. Epub 2017 Oct 24.

25.

Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety.

Sansook S, Ocasio CA, Day IJ, Tizzard GJ, Coles SJ, Fedorov O, Bennett JM, Elkins JM, Spencer J.

Org Biomol Chem. 2017 Oct 18;15(40):8655-8660. doi: 10.1039/c7ob02289a. Erratum in: Org Biomol Chem. 2018 Jan 3;16(2):336.

26.

Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7.

Gerken PA, Wolstenhulme JR, Tumber A, Hatch SB, Zhang Y, Müller S, Chandler SA, Mair B, Li F, Nijman SMB, Konietzny R, Szommer T, Yapp C, Fedorov O, Benesch JLP, Vedadi M, Kessler BM, Kawamura A, Brennan PE, Smith MD.

Angew Chem Int Ed Engl. 2017 Dec 4;56(49):15555-15559. doi: 10.1002/anie.201706788. Epub 2017 Nov 7.

27.

Determination of the Spin and Parity of the Z_{c}(3900).

Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, Bertani M, Bettoni D, Bian JM, Bianchi F, Boger E, Boyko I, Briere RA, Cai H, Cai X, Cakir O, Calcaterra A, Cao GF, Cetin SA, Chang JF, Chelkov G, Chen G, Chen HS, Chen HY, Chen JC, Chen ML, Chen S, Chen SJ, Chen X, Chen XR, Chen YB, Cheng HP, Chu XK, Cibinetto G, Dai HL, Dai JP, Dbeyssi A, Dedovich D, Deng ZY, Denig A, Denysenko I, Destefanis M, De Mori F, Ding Y, Dong C, Dong J, Dong LY, Dong MY, Dou ZL, Du SX, Duan PF, Fan JZ, Fang J, Fang SS, Fang X, Fang Y, Farinelli R, Fava L, Fedorov O, Feldbauer F, Felici G, Feng CQ, Fioravanti E, Fritsch M, Fu CD, Gao Q, Gao XL, Gao XY, Gao Y, Gao Z, Garzia I, Goetzen K, Gong L, Gong WX, Gradl W, Greco M, Gu MH, Gu YT, Guan YH, Guo AQ, Guo LB, Guo RP, Guo Y, Guo YP, Haddadi Z, Hafner A, Han S, Hao XQ, Harris FA, He KL, Held T, Heng YK, Hou ZL, Hu C, Hu HM, Hu JF, Hu T, Hu Y, Huang GS, Huang JS, Huang XT, Huang XZ, Huang Y, Huang ZL, Hussain T, Ji Q, Ji QP, Ji XB, Ji XL, Jiang LW, Jiang XS, Jiang XY, Jiao JB, Jiao Z, Jin DP, Jin S, Johansson T, Julin A, Kalantar-Nayestanaki N, Kang XL, Kang XS, Kavatsyuk M, Ke BC, Kiese P, Kliemt R, Kloss B, Kolcu OB, Kopf B, Kornicer M, Kuehn W, Kupsc A, Lange JS, Lara M, Larin P, Leng C, Li C, Li C, Li DM, Li F, Li FY, Li G, Li HB, Li HJ, Li JC, Li J, Li K, Li K, Li L, Li PR, Li QY, Li T, Li WD, Li WG, Li XL, Li XM, Li XN, Li XQ, Li YB, Li ZB, Liang H, Liang JJ, Liang YF, Liang YT, Liao GR, Lin DX, Liu B, Liu BJ, Liu CX, Liu D, Liu FH, Liu F, Liu F, Liu HB, Liu HH, Liu HH, Liu HM, Liu J, Liu JB, Liu JP, Liu JY, Liu K, Liu KY, Liu LD, Liu PL, Liu Q, Liu SB, Liu X, Liu YB, Liu ZA, Liu Z, Loehner H, Lou XC, Lu HJ, Lu JG, Lu Y, Lu YP, Luo CL, Luo MX, Luo T, Luo XL, Lyu XR, Ma FC, Ma HL, Ma LL, Ma MM, Ma QM, Ma T, Ma XN, Ma XY, Ma YM, Maas FE, Maggiora M, Mao YJ, Mao ZP, Marcello S, Messchendorp JG, Min J, Mitchell RE, Mo XH, Mo YJ, Morales CM, Muchnoi NY, Muramatsu H, Nefedov Y, Nerling F, Nikolaev IB, Ning Z, Nisar S, Niu SL, Niu XY, Olsen SL, Ouyang Q, Pacetti S, Pan Y, Patteri P, Pelizaeus M, Peng HP, Peters K, Pettersson J, Ping JL, Ping RG, Poling R, Prasad V, Qi HR, Qi M, Qian S, Qiao CF, Qin LQ, Qin N, Qin XS, Qin ZH, Qiu JF, Rashid KH, Redmer CF, Ripka M, Rong G, Rosner C, Ruan XD, Sarantsev A, Savrié M, Schoenning K, Schumann S, Shan W, Shao M, Shen CP, Shen PX, Shen XY, Sheng HY, Shi M, Song WM, Song XY, Sosio S, Spataro S, Sun GX, Sun JF, Sun SS, Sun XH, Sun YJ, Sun YZ, Sun ZJ, Sun ZT, Tang CJ, Tang X, Tapan I, Thorndike EH, Tiemens M, Ullrich M, Uman I, Varner GS, Wang B, Wang BL, Wang D, Wang DY, Wang K, Wang LL, Wang LS, Wang M, Wang P, Wang PL, Wang SG, Wang W, Wang WP, Wang XF, Wang Y, Wang YD, Wang YF, Wang YQ, Wang Z, Wang ZG, Wang ZH, Wang ZY, Wang ZY, Weber T, Wei DH, Wei JB, Weidenkaff P, Wen SP, Wiedner U, Wolke M, Wu LH, Wu LJ, Wu Z, Xia L, Xia LG, Xia Y, Xiao D, Xiao H, Xiao ZJ, Xie YG, Xiu QL, Xu GF, Xu JJ, Xu L, Xu QJ, Xu QN, Xu XP, Yan L, Yan WB, Yan WC, Yan YH, Yang HJ, Yang HX, Yang L, Yang YX, Ye M, Ye MH, Yin JH, Yu BX, Yu CX, Yu JS, Yuan CZ, Yuan WL, Yuan Y, Yuncu A, Zafar AA, Zallo A, Zeng Y, Zeng Z, Zhang BX, Zhang BY, Zhang C, Zhang CC, Zhang DH, Zhang HH, Zhang HY, Zhang J, Zhang JJ, Zhang JL, Zhang JQ, Zhang JW, Zhang JY, Zhang JZ, Zhang K, Zhang L, Zhang SQ, Zhang XY, Zhang Y, Zhang YH, Zhang YN, Zhang YT, Zhang Y, Zhang ZH, Zhang ZP, Zhang ZY, Zhao G, Zhao JW, Zhao JY, Zhao JZ, Zhao L, Zhao L, Zhao MG, Zhao Q, Zhao QW, Zhao SJ, Zhao TC, Zhao YB, Zhao ZG, Zhemchugov A, Zheng B, Zheng JP, Zheng WJ, Zheng YH, Zhong B, Zhou L, Zhou X, Zhou XK, Zhou XR, Zhou XY, Zhu K, Zhu KJ, Zhu S, Zhu SH, Zhu XL, Zhu YC, Zhu YS, Zhu ZA, Zhuang J, Zotti L, Zou BS, Zou JH; BESIII Collaboration.

Phys Rev Lett. 2017 Aug 18;119(7):072001. doi: 10.1103/PhysRevLett.119.072001. Epub 2017 Aug 16.

28.

Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation.

Meier JC, Tallant C, Fedorov O, Witwicka H, Hwang SY, van Stiphout RG, Lambert JP, Rogers C, Yapp C, Gerstenberger BS, Fedele V, Savitsky P, Heidenreich D, Daniels DL, Owen DR, Fish PV, Igoe NM, Bayle ED, Haendler B, Oppermann UCT, Buffa F, Brennan PE, Müller S, Gingras AC, Odgren PR, Birnbaum MJ, Knapp S.

ACS Chem Biol. 2017 Oct 20;12(10):2619-2630. doi: 10.1021/acschembio.7b00481. Epub 2017 Sep 12.

29.

Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein.

Carr SM, Munro S, Sagum CA, Fedorov O, Bedford MT, La Thangue NB.

Cell Death Differ. 2017 Dec;24(12):2139-2149. doi: 10.1038/cdd.2017.135. Epub 2017 Aug 25.

30.

Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins.

Igoe N, Bayle ED, Tallant C, Fedorov O, Meier JC, Savitsky P, Rogers C, Morias Y, Scholze S, Boyd H, Cunoosamy D, Andrews DM, Cheasty A, Brennan PE, Müller S, Knapp S, Fish PV.

J Med Chem. 2017 Aug 24;60(16):6998-7011. doi: 10.1021/acs.jmedchem.7b00611. Epub 2017 Aug 10.

PMID:
28714688
31.

Observation of ψ(3686)→e^{+}e^{-}χ_{cJ} and χ_{cJ}→e^{+}e^{-}J/ψ.

Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, Bertani M, Bettoni D, Bian JM, Bianchi F, Boger E, Boyko I, Briere RA, Cai H, Cai X, Cakir O, Calcaterra A, Cao GF, Cetin SA, Chang JF, Chelkov G, Chen G, Chen HS, Chen HY, Chen JC, Chen ML, Chen S, Chen SJ, Chen X, Chen XR, Chen YB, Cheng HP, Chu XK, Cibinetto G, Dai HL, Dai JP, Dbeyssi A, Dedovich D, Deng ZY, Denig A, Denysenko I, Destefanis M, De Mori F, Ding Y, Dong C, Dong J, Dong LY, Dong MY, Dou ZL, Du SX, Duan PF, Fan JZ, Fang J, Fang SS, Fang X, Fang Y, Farinelli R, Fava L, Fedorov O, Feldbauer F, Felici G, Feng CQ, Fioravanti E, Fritsch M, Fu CD, Gao Q, Gao XL, Gao XY, Gao Y, Gao Z, Garzia I, Goetzen K, Gong L, Gong WX, Gradl W, Greco M, Gu MH, Gu YT, Guan YH, Guo AQ, Guo LB, Guo RP, Guo Y, Guo YP, Haddadi Z, Hafner A, Han S, Hao XQ, Harris FA, He KL, Held T, Heng YK, Hou ZL, Hu C, Hu HM, Hu JF, Hu T, Hu Y, Huang GS, Huang JS, Huang XT, Huang XZ, Huang Y, Huang ZL, Hussain T, Ji Q, Ji QP, Ji XB, Ji XL, Jiang LW, Jiang XS, Jiang XY, Jiao JB, Jiao Z, Jin DP, Jin S, Johansson T, Julin A, Kalantar-Nayestanaki N, Kang XL, Kang XS, Kavatsyuk M, Ke BC, Kiese P, Kliemt R, Kloss B, Kolcu OB, Kopf B, Kornicer M, Kupsc A, Kühn W, Lange JS, Lara M, Larin P, Leng C, Li C, Li C, Li DM, Li F, Li FY, Li G, Li HB, Li HJ, Li JC, Li J, Li K, Li K, Li L, Li PR, Li QY, Li T, Li WD, Li WG, Li XL, Li XN, Li XQ, Li YB, Li ZB, Liang H, Liang YF, Liang YT, Liao GR, Lin DX, Liu B, Liu BJ, Liu CX, Liu D, Liu FH, Liu F, Liu F, Liu HB, Liu HH, Liu HH, Liu HM, Liu J, Liu JB, Liu JP, Liu JY, Liu K, Liu KY, Liu LD, Liu PL, Liu Q, Liu SB, Liu X, Liu YB, Liu ZA, Liu Z, Loehner H, Lou XC, Lu HJ, Lu JG, Lu Y, Lu YP, Luo CL, Luo MX, Luo T, Luo XL, Lyu XR, Ma FC, Ma HL, Ma LL, Ma MM, Ma QM, Ma T, Ma XN, Ma XY, Ma YM, Maas FE, Maggiora M, Mao YJ, Mao ZP, Marcello S, Messchendorp JG, Min J, Mitchell RE, Mo XH, Mo YJ, Morales Morales C, Muchnoi NY, Muramatsu H, Nefedov Y, Nerling F, Nikolaev IB, Ning Z, Nisar S, Niu SL, Niu XY, Olsen SL, Ouyang Q, Pacetti S, Pan Y, Patteri P, Pelizaeus M, Peng HP, Peters K, Pettersson J, Ping JL, Ping RG, Poling R, Prasad V, Qi HR, Qi M, Qian S, Qiao CF, Qin LQ, Qin N, Qin XS, Qin ZH, Qiu JF, Rashid KH, Redmer CF, Ripka M, Rong G, Rosner C, Ruan XD, Sarantsev A, Savrié M, Schoenning K, Schumann S, Shan W, Shao M, Shen CP, Shen PX, Shen XY, Sheng HY, Shi M, Song WM, Song XY, Sosio S, Spataro S, Sun GX, Sun JF, Sun SS, Sun XH, Sun YJ, Sun YZ, Sun ZJ, Sun ZT, Tang CJ, Tang X, Tapan I, Thorndike EH, Tiemens M, Ullrich M, Uman I, Varner GS, Wang B, Wang BL, Wang D, Wang DY, Wang K, Wang LL, Wang LS, Wang M, Wang P, Wang PL, Wang SG, Wang W, Wang WP, Wang XF, Wang Y, Wang YD, Wang YF, Wang YQ, Wang Z, Wang ZG, Wang ZH, Wang ZY, Wang ZY, Weber T, Wei DH, Wei JB, Weidenkaff P, Wen SP, Wiedner U, Wolke M, Wu LH, Wu LJ, Wu Z, Xia L, Xia LG, Xia Y, Xiao D, Xiao H, Xiao ZJ, Xie YG, Xiu QL, Xu GF, Xu JJ, Xu L, Xu QJ, Xu QN, Xu XP, Yan L, Yan WB, Yan WC, Yan YH, Yang HJ, Yang HX, Yang L, Yang YX, Ye M, Ye MH, Yin JH, Yu BX, Yu CX, Yu JS, Yuan CZ, Yuan WL, Yuan Y, Yuncu A, Zafar AA, Zallo A, Zeng Y, Zeng Z, Zhang BX, Zhang BY, Zhang C, Zhang CC, Zhang DH, Zhang HH, Zhang HY, Zhang J, Zhang JJ, Zhang JL, Zhang JQ, Zhang JW, Zhang JY, Zhang JZ, Zhang K, Zhang L, Zhang SQ, Zhang XY, Zhang Y, Zhang YH, Zhang YN, Zhang YT, Zhang Y, Zhang ZH, Zhang ZP, Zhang ZY, Zhao G, Zhao JW, Zhao JY, Zhao JZ, Zhao L, Zhao L, Zhao MG, Zhao Q, Zhao QW, Zhao SJ, Zhao TC, Zhao YB, Zhao ZG, Zhemchugov A, Zheng B, Zheng JP, Zheng WJ, Zheng YH, Zhong B, Zhou L, Zhou X, Zhou XK, Zhou XR, Zhou XY, Zhu K, Zhu KJ, Zhu S, Zhu SH, Zhu XL, Zhu YC, Zhu YS, Zhu ZA, Zhuang J, Zotti L, Zou BS, Zou JH; BESIII Collaboration.

Phys Rev Lett. 2017 Jun 2;118(22):221802. doi: 10.1103/PhysRevLett.118.221802. Epub 2017 May 30.

PMID:
28622000
32.

Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains.

Bouché L, Christ CD, Siegel S, Fernández-Montalván AE, Holton SJ, Fedorov O, Ter Laak A, Sugawara T, Stöckigt D, Tallant C, Bennett J, Monteiro O, Díaz-Sáez L, Siejka P, Meier J, Pütter V, Weiske J, Müller S, Huber KVM, Hartung IV, Haendler B.

J Med Chem. 2017 May 11;60(9):4002-4022. doi: 10.1021/acs.jmedchem.7b00306. Epub 2017 May 1.

33.

Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.

Bataille CJ, Brennan MB, Byrne S, Davies SG, Durbin M, Fedorov O, Huber KV, Jones AM, Knapp S, Liu G, Nadali A, Quevedo CE, Russell AJ, Walker RG, Westwood R, Wynne GM.

Bioorg Med Chem. 2017 May 1;25(9):2657-2665. doi: 10.1016/j.bmc.2017.02.056. Epub 2017 Feb 28.

PMID:
28341403
34.

Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1.

Santamaria S, Fedorov O, McCafferty J, Murphy G, Dudhia J, Nagase H, Yamamoto K.

MAbs. 2017 May/Jun;9(4):595-602. doi: 10.1080/19420862.2017.1304341. Epub 2017 Mar 17.

35.

Assessing histone demethylase inhibitors in cells: lessons learned.

Hatch SB, Yapp C, Montenegro RC, Savitsky P, Gamble V, Tumber A, Ruda GF, Bavetsias V, Fedorov O, Atrash B, Raynaud F, Lanigan R, Carmichael L, Tomlin K, Burke R, Westaway SM, Brown JA, Prinjha RK, Martinez ED, Oppermann U, Schofield CJ, Bountra C, Kawamura A, Blagg J, Brennan PE, Rossanese O, Müller S.

Epigenetics Chromatin. 2017 Mar 1;10:9. doi: 10.1186/s13072-017-0116-6. eCollection 2017.

36.

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.

Tumber A, Nuzzi A, Hookway ES, Hatch SB, Velupillai S, Johansson C, Kawamura A, Savitsky P, Yapp C, Szykowska A, Wu N, Bountra C, Strain-Damerell C, Burgess-Brown NA, Ruda GF, Fedorov O, Munro S, England KS, Nowak RP, Schofield CJ, La Thangue NB, Pawlyn C, Davies F, Morgan G, Athanasou N, Müller S, Oppermann U, Brennan PE.

Cell Chem Biol. 2017 Mar 16;24(3):371-380. doi: 10.1016/j.chembiol.2017.02.006. Epub 2017 Mar 2.

37.

Synthesis of gem-Difluorinated Hydroxypyrrolidines.

Fedorov OV, Struchkova MI, Dilman AD.

J Org Chem. 2017 Mar 17;82(6):3270-3275. doi: 10.1021/acs.joc.6b03033. Epub 2017 Mar 2.

PMID:
28218543
38.

Amplitude Analysis of the Decays η^{'}→π^{+}π^{-}π^{0} and η^{'}→π^{0}π^{0}π^{0}.

Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, Bertani M, Bettoni D, Bian JM, Bianchi F, Boger E, Boyko I, Briere RA, Cai H, Cai X, Cakir O, Calcaterra A, Cao GF, Cetin SA, Chang JF, Chelkov G, Chen G, Chen HS, Chen HY, Chen JC, Chen ML, Chen S, Chen SJ, Chen X, Chen XR, Chen YB, Cheng HP, Chu XK, Cibinetto G, Dai HL, Dai JP, Dbeyssi A, Dedovich D, Deng ZY, Denig A, Denysenko I, Destefanis M, De Mori F, Ding Y, Dong C, Dong J, Dong LY, Dong MY, Dou ZL, Du SX, Duan PF, Fan JZ, Fang J, Fang SS, Fang X, Fang Y, Farinelli R, Fava L, Fedorov O, Feldbauer F, Felici G, Feng CQ, Fioravanti E, Fritsch M, Fu CD, Gao Q, Gao XL, Gao XY, Gao Y, Gao Z, Garzia I, Goetzen K, Gong L, Gong WX, Gradl W, Greco M, Gu MH, Gu YT, Guan YH, Guo AQ, Guo LB, Guo RP, Guo Y, Guo YP, Haddadi Z, Hafner A, Han S, Hao XQ, Harris FA, He KL, Held T, Heng YK, Hou ZL, Hu C, Hu HM, Hu JF, Hu T, Hu Y, Huang GS, Huang JS, Huang XT, Huang XZ, Huang Y, Huang ZL, Hussain T, Ji Q, Ji QP, Ji XB, Ji XL, Jiang LW, Jiang XS, Jiang XY, Jiao JB, Jiao Z, Jin DP, Jin S, Johansson T, Julin A, Kalantar-Nayestanaki N, Kang XL, Kang XS, Kavatsyuk M, Ke BC, Kiese P, Kliemt R, Kloss B, Kolcu OB, Kopf B, Kornicer M, Kupsc A, Kühn W, Lange JS, Lara M, Larin P, Leng C, Li C, Li C, Li DM, Li F, Li FY, Li G, Li HB, Li HJ, Li JC, Li J, Li K, Li K, Li L, Li PR, Li QY, Li T, Li WD, Li WG, Li XL, Li XN, Li XQ, Li YB, Li ZB, Liang H, Liang YF, Liang YT, Liao GR, Lin DX, Liu B, Liu BJ, Liu CX, Liu D, Liu FH, Liu F, Liu F, Liu HB, Liu HH, Liu HH, Liu HM, Liu J, Liu JB, Liu JP, Liu JY, Liu K, Liu KY, Liu LD, Liu PL, Liu Q, Liu SB, Liu X, Liu YB, Liu ZA, Liu Z, Loehner H, Lou XC, Lu HJ, Lu JG, Lu Y, Lu YP, Luo CL, Luo MX, Luo T, Luo XL, Lyu XR, Ma FC, Ma HL, Ma LL, Ma MM, Ma QM, Ma T, Ma XN, Ma XY, Ma YM, Maas FE, Maggiora M, Mao YJ, Mao ZP, Marcello S, Messchendorp JG, Min J, Min TJ, Mitchell RE, Mo XH, Mo YJ, Morales Morales C, Muchnoi NY, Muramatsu H, Nefedov Y, Nerling F, Nikolaev IB, Ning Z, Nisar S, Niu SL, Niu XY, Olsen SL, Ouyang Q, Pacetti S, Pan Y, Patteri P, Pelizaeus M, Peng HP, Peters K, Pettersson J, Ping JL, Ping RG, Poling R, Prasad V, Qi HR, Qi M, Qian S, Qiao CF, Qin LQ, Qin N, Qin XS, Qin ZH, Qiu JF, Rashid KH, Redmer CF, Ripka M, Rong G, Rosner C, Ruan XD, Sarantsev A, Savrié M, Schoenning K, Schumann S, Shan W, Shao M, Shen CP, Shen PX, Shen XY, Sheng HY, Shi M, Song WM, Song XY, Sosio S, Spataro S, Sun GX, Sun JF, Sun SS, Sun XH, Sun YJ, Sun YZ, Sun ZJ, Sun ZT, Tang CJ, Tang X, Tapan I, Thorndike EH, Tiemens M, Ullrich M, Uman I, Varner GS, Wang B, Wang BL, Wang D, Wang DY, Wang K, Wang LL, Wang LS, Wang M, Wang P, Wang PL, Wang W, Wang WP, Wang XF, Wang Y, Wang YD, Wang YF, Wang YQ, Wang Z, Wang ZG, Wang ZH, Wang ZY, Wang ZY, Weber T, Wei DH, Weidenkaff P, Wen SP, Wiedner U, Wolke M, Wu LH, Wu LJ, Wu Z, Xia L, Xia LG, Xia Y, Xiao D, Xiao H, Xiao ZJ, Xie YG, Xiu QL, Xu GF, Xu JJ, Xu L, Xu QJ, Xu QN, Xu XP, Yan L, Yan WB, Yan WC, Yan YH, Yang HJ, Yang HX, Yang L, Yang YX, Ye M, Ye MH, Yin JH, Yu BX, Yu CX, Yu JS, Yuan CZ, Yuan WL, Yuan Y, Yuncu A, Zafar AA, Zallo A, Zeng Y, Zeng Z, Zhang BX, Zhang BY, Zhang C, Zhang CC, Zhang DH, Zhang HH, Zhang HY, Zhang J, Zhang JJ, Zhang JL, Zhang JQ, Zhang JW, Zhang JY, Zhang JZ, Zhang K, Zhang L, Zhang SQ, Zhang XY, Zhang Y, Zhang YH, Zhang YN, Zhang YT, Zhang Y, Zhang ZH, Zhang ZP, Zhang ZY, Zhao G, Zhao JW, Zhao JY, Zhao JZ, Zhao L, Zhao L, Zhao MG, Zhao Q, Zhao QW, Zhao SJ, Zhao TC, Zhao YB, Zhao ZG, Zhemchugov A, Zheng B, Zheng JP, Zheng WJ, Zheng YH, Zhong B, Zhou L, Zhou X, Zhou XK, Zhou XR, Zhou XY, Zhu K, Zhu KJ, Zhu S, Zhu SH, Zhu XL, Zhu YC, Zhu YS, Zhu ZA, Zhuang J, Zotti L, Zou BS, Zou JH; BESIII Collaboration.

Phys Rev Lett. 2017 Jan 6;118(1):012001. doi: 10.1103/PhysRevLett.118.012001. Epub 2017 Jan 5.

39.

Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies.

Igoe N, Bayle ED, Fedorov O, Tallant C, Savitsky P, Rogers C, Owen DR, Deb G, Somervaille TC, Andrews DM, Jones N, Cheasty A, Ryder H, Brennan PE, Müller S, Knapp S, Fish PV.

J Med Chem. 2017 Jan 26;60(2):668-680. doi: 10.1021/acs.jmedchem.6b01583. Epub 2017 Jan 9.

PMID:
28068087
40.

CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation.

Olzscha H, Fedorov O, Kessler BM, Knapp S, La Thangue NB.

Cell Chem Biol. 2017 Jan 19;24(1):9-23. doi: 10.1016/j.chembiol.2016.11.009. Epub 2016 Dec 15.

41.

Discovery of a PCAF Bromodomain Chemical Probe.

Moustakim M, Clark PG, Trulli L, Fuentes de Arriba AL, Ehebauer MT, Chaikuad A, Murphy EJ, Mendez-Johnson J, Daniels D, Hou CD, Lin YH, Walker JR, Hui R, Yang H, Dorrell L, Rogers CM, Monteiro OP, Fedorov O, Huber KV, Knapp S, Heer J, Dixon DJ, Brennan PE.

Angew Chem Int Ed Engl. 2017 Jan 16;56(3):827-831. doi: 10.1002/anie.201610816. Epub 2016 Dec 14.

42.

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.

Picaud S, Leonards K, Lambert JP, Dovey O, Wells C, Fedorov O, Monteiro O, Fujisawa T, Wang CY, Lingard H, Tallant C, Nikbin N, Guetzoyan L, Ingham R, Ley SV, Brennan P, Muller S, Samsonova A, Gingras AC, Schwaller J, Vassiliou G, Knapp S, Filippakopoulos P.

Sci Adv. 2016 Oct 12;2(10):e1600760. eCollection 2016 Oct.

43.

Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors.

Popp TA, Tallant C, Rogers C, Fedorov O, Brennan PE, Müller S, Knapp S, Bracher F.

J Med Chem. 2016 Oct 13;59(19):8889-8912. Epub 2016 Sep 27.

PMID:
27673482
44.

Silicon Reagent with Functionalized Tetrafluoroethylene Fragments: Preparation and Coupling with Aldehydes.

Fedorov OV, Struchkova MI, Dilman AD.

J Org Chem. 2016 Oct 7;81(19):9455-9460. Epub 2016 Sep 23.

PMID:
27627651
45.

Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis.

Myrianthopoulos V, Gaboriaud-Kolar N, Tallant C, Hall ML, Grigoriou S, Brownlee PM, Fedorov O, Rogers C, Heidenreich D, Wanior M, Drosos N, Mexia N, Savitsky P, Bagratuni T, Kastritis E, Terpos E, Filippakopoulos P, Müller S, Skaltsounis AL, Downs JA, Knapp S, Mikros E.

J Med Chem. 2016 Oct 13;59(19):8787-8803. Epub 2016 Sep 27.

46.

Observation of an Anomalous Line Shape of the η^{'}π^{+}π^{-} Mass Spectrum near the pp[over ¯] Mass Threshold in J/ψ→γη^{'}π^{+}π^{-}.

Ablikim M, Achasov MN, Ahmed S, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, Berger N, Bertani M, Bettoni D, Bian JM, Bianchi F, Boger E, Boyko I, Briere RA, Cai H, Cai X, Cakir O, Calcaterra A, Cao GF, Cetin SA, Chang JF, Chelkov G, Chen G, Chen HS, Chen HY, Chen JC, Chen ML, Chen S, Chen SJ, Chen X, Chen XR, Chen YB, Cheng HP, Chu XK, Cibinetto G, Dai HL, Dai JP, Dbeyssi A, Dedovich D, Deng ZY, Denig A, Denysenko I, Destefanis M, De Mori F, Ding Y, Dong C, Dong J, Dong LY, Dong MY, Dou ZL, Du SX, Duan PF, Fan JZ, Fang J, Fang SS, Fang X, Fang Y, Farinelli R, Fava L, Fedorov O, Feldbauer F, Felici G, Feng CQ, Fioravanti E, Fritsch M, Fu CD, Gao Q, Gao XL, Gao XY, Gao Y, Gao Z, Garzia I, Goetzen K, Gong L, Gong WX, Gradl W, Greco M, Gu MH, Gu YT, Guan YH, Guo AQ, Guo LB, Guo RP, Guo Y, Guo YP, Haddadi Z, Hafner A, Han S, Hao XQ, Harris FA, He KL, Heinsius FH, Held T, Heng YK, Holtmann T, Hou ZL, Hu C, Hu HM, Hu JF, Hu T, Hu Y, Huang GS, Huang YP, Huang JS, Huang XT, Huang XZ, Huang Y, Huang ZL, Hussain T, Ji Q, Ji QP, Ji XB, Ji XL, Jiang LW, Jiang XS, Jiang XY, Jiao JB, Jiao Z, Jin DP, Jin S, Johansson T, Julin A, Kalantar-Nayestanaki N, Kang XL, Kang XS, Kavatsyuk M, Ke BC, Kiese P, Kliemt R, Kloss B, Kolcu OB, Kopf B, Kornicer M, Kupsc A, Kühn W, Lange JS, Lara M, Larin P, Leithoff H, Leng C, Li C, Li C, Li DM, Li F, Li FY, Li G, Li HB, Li HJ, Li JC, Li J, Li K, Li K, Li L, Li PR, Li QY, Li T, Li WD, Li WG, Li XL, Li XN, Li XQ, Li YB, Li ZB, Liang H, Liang YF, Liang YT, Liao GR, Lin DX, Liu B, Liu BJ, Liu CX, Liu D, Liu FH, Liu F, Liu F, Liu HB, Liu HH, Liu HH, Liu HM, Liu J, Liu JB, Liu JP, Liu JY, Liu K, Liu KY, Liu LD, Liu PL, Liu Q, Liu SB, Liu X, Liu YB, Liu YY, Liu ZA, Liu Z, Loehner H, Lou XC, Lu HJ, Lu JG, Lu Y, Lu YP, Luo CL, Luo MX, Luo T, Luo XL, Lyu XR, Ma FC, Ma HL, Ma LL, Ma MM, Ma QM, Ma T, Ma XN, Ma XY, Ma YM, Maas FE, Maggiora M, Malik QA, Mao YJ, Mao ZP, Marcello S, Messchendorp JG, Mezzadri G, Min J, Min TJ, Mitchell RE, Mo XH, Mo YJ, Morales Morales C, Muchnoi NY, Muramatsu H, Musiol P, Nefedov Y, Nerling F, Nikolaev IB, Ning Z, Nisar S, Niu SL, Niu XY, Olsen SL, Ouyang Q, Pacetti S, Pan Y, Patteri P, Pelizaeus M, Peng HP, Peters K, Pettersson J, Ping JL, Ping RG, Poling R, Prasad V, Qi HR, Qi M, Qian S, Qiao CF, Qin LQ, Qin N, Qin XS, Qin ZH, Qiu JF, Rashid KH, Redmer CF, Ripka M, Rong G, Rosner Ch, Ruan XD, Sarantsev A, Savrié M, Schnier C, Schoenning K, Schumann S, Shan W, Shao M, Shen CP, Shen PX, Shen XY, Sheng HY, Shi M, Song WM, Song XY, Sosio S, Spataro S, Sun GX, Sun JF, Sun SS, Sun XH, Sun YJ, Sun YZ, Sun ZJ, Sun ZT, Tang CJ, Tang X, Tapan I, Thorndike EH, Tiemens M, Uman I, Varner GS, Wang B, Wang BL, Wang D, Wang DY, Wang K, Wang LL, Wang LS, Wang M, Wang P, Wang PL, Wang SG, Wang W, Wang WP, Wang XF, Wang Y, Wang YD, Wang YF, Wang YQ, Wang Z, Wang ZG, Wang ZH, Wang ZY, Wang ZY, Weber T, Wei DH, Wei JB, Weidenkaff P, Wen SP, Wiedner U, Wolke M, Wu LH, Wu LJ, Wu Z, Xia L, Xia LG, Xia Y, Xiao D, Xiao H, Xiao ZJ, Xie YG, Xiu QL, Xu GF, Xu JJ, Xu L, Xu QJ, Xu QN, Xu XP, Yan L, Yan WB, Yan WC, Yan YH, Yang HJ, Yang HX, Yang L, Yang YX, Ye M, Ye MH, Yin JH, Yu BX, Yu CX, Yu JS, Yuan CZ, Yuan WL, Yuan Y, Yuncu A, Zafar AA, Zallo A, Zeng Y, Zeng Z, Zhang BX, Zhang BY, Zhang C, Zhang CC, Zhang DH, Zhang HH, Zhang HY, Zhang J, Zhang JJ, Zhang JL, Zhang JQ, Zhang JW, Zhang JY, Zhang JZ, Zhang K, Zhang L, Zhang SQ, Zhang XY, Zhang Y, Zhang YH, Zhang YN, Zhang YT, Zhang Y, Zhang ZH, Zhang ZP, Zhang ZY, Zhao G, Zhao JW, Zhao JY, Zhao JZ, Zhao L, Zhao L, Zhao MG, Zhao Q, Zhao QW, Zhao SJ, Zhao TC, Zhao YB, Zhao ZG, Zhemchugov A, Zheng B, Zheng JP, Zheng WJ, Zheng YH, Zhong B, Zhou L, Zhou X, Zhou XK, Zhou XR, Zhou XY, Zhu K, Zhu KJ, Zhu S, Zhu SH, Zhu XL, Zhu YC, Zhu YS, Zhu ZA, Zhuang J, Zotti L, Zou BS, Zou JH; BESIII Collaboration.

Phys Rev Lett. 2016 Jul 22;117(4):042002. doi: 10.1103/PhysRevLett.117.042002. Epub 2016 Jul 21.

47.

Observation of h_{c} Radiative Decay h_{c}→γη^{'} and Evidence for h_{c}→γη.

Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, Bertani M, Bettoni D, Bian JM, Bianchi F, Boger E, Boyko I, Briere RA, Cai H, Cai X, Cakir O, Calcaterra A, Cao GF, Cetin SA, Chang JF, Chelkov G, Chen G, Chen HS, Chen HY, Chen JC, Chen ML, Chen S, Chen SJ, Chen X, Chen XR, Chen YB, Cheng HP, Chu XK, Cibinetto G, Dai HL, Dai JP, Dbeyssi A, Dedovich D, Deng ZY, Denig A, Denysenko I, Destefanis M, De Mori F, Ding Y, Dong C, Dong J, Dong LY, Dong MY, Dou ZL, Du SX, Duan PF, Fan JZ, Fang J, Fang SS, Fang X, Fang Y, Farinelli R, Fava L, Fedorov O, Feldbauer F, Felici G, Feng CQ, Fioravanti E, Fritsch M, Fu CD, Gao Q, Gao XL, Gao XY, Gao Y, Gao Z, Garzia I, Goetzen K, Gong L, Gong WX, Gradl W, Greco M, Gu MH, Gu YT, Guan YH, Guo AQ, Guo LB, Guo RP, Guo Y, Guo YP, Haddadi Z, Hafner A, Han S, Hao XQ, Harris FA, He KL, Held T, Heng YK, Hou ZL, Hu C, Hu HM, Hu JF, Hu T, Hu Y, Huang GS, Huang JS, Huang XT, Huang XZ, Huang Y, Huang ZL, Hussain T, Ji Q, Ji QP, Ji XB, Ji XL, Jiang LW, Jiang XS, Jiang XY, Jiao JB, Jiao Z, Jin DP, Jin S, Johansson T, Julin A, Kalantar-Nayestanaki N, Kang XL, Kang XS, Kavatsyuk M, Ke BC, Kiese P, Kliemt R, Kloss B, Kolcu OB, Kopf B, Kornicer M, Kupsc A, Kühn W, Lange JS, Lara M, Larin P, Leng C, Li C, Li C, Li DM, Li F, Li FY, Li G, Li HB, Li HJ, Li JC, Li J, Li K, Li K, Li L, Li PR, Li QY, Li T, Li WD, Li WG, Li XL, Li XN, Li XQ, Li YB, Li ZB, Liang H, Liang YF, Liang YT, Liao GR, Lin DX, Liu B, Liu BJ, Liu CX, Liu D, Liu FH, Liu F, Liu F, Liu HB, Liu HH, Liu HH, Liu HM, Liu J, Liu JB, Liu JP, Liu JY, Liu K, Liu KY, Liu LD, Liu PL, Liu Q, Liu SB, Liu X, Liu YB, Liu ZA, Liu Z, Loehner H, Lou XC, Lu HJ, Lu JG, Lu Y, Lu YP, Luo CL, Luo MX, Luo T, Luo XL, Lyu XR, Ma FC, Ma HL, Ma LL, Ma MM, Ma QM, Ma T, Ma XN, Ma XY, Ma YM, Maas FE, Maggiora M, Mao YJ, Mao ZP, Marcello S, Messchendorp JG, Min J, Mitchell RE, Mo XH, Mo YJ, Morales Morales C, Muchnoi NY, Muramatsu H, Nefedov Y, Nerling F, Nikolaev IB, Ning Z, Nisar S, Niu SL, Niu XY, Olsen SL, Ouyang Q, Pacetti S, Pan Y, Patteri P, Pelizaeus M, Peng HP, Peters K, Pettersson J, Ping JL, Ping RG, Poling R, Prasad V, Qi HR, Qi M, Qian S, Qiao CF, Qin LQ, Qin N, Qin XS, Qin ZH, Qiu JF, Rashid KH, Redmer CF, Ripka M, Rong G, Rosner Ch, Ruan XD, Sarantsev A, Savrié M, Schoenning K, Schumann S, Shan W, Shao M, Shen CP, Shen PX, Shen XY, Sheng HY, Shi M, Song WM, Song XY, Sosio S, Spataro S, Sun GX, Sun JF, Sun SS, Sun XH, Sun YJ, Sun YZ, Sun ZJ, Sun ZT, Tang CJ, Tang X, Tapan I, Thorndike EH, Tiemens M, Ullrich M, Uman I, Varner GS, Wang B, Wang BL, Wang D, Wang DY, Wang K, Wang LL, Wang LS, Wang M, Wang P, Wang PL, Wang SG, Wang W, Wang WP, Wang XF, Wang Y, Wang YD, Wang YF, Wang YQ, Wang Z, Wang ZG, Wang ZH, Wang ZY, Wang ZY, Weber T, Wei DH, Wei JB, Weidenkaff P, Wen SP, Wiedner U, Wolke M, Wu LH, Wu LJ, Wu Z, Xia L, Xia LG, Xia Y, Xiao D, Xiao H, Xiao ZJ, Xie YG, Xiu QL, Xu GF, Xu JJ, Xu L, Xu QJ, Xu QN, Xu XP, Yan L, Yan WB, Yan WC, Yan YH, Yang HJ, Yang HX, Yang L, Yang YX, Ye M, Ye MH, Yin JH, Yu BX, Yu CX, Yu JS, Yuan CZ, Yuan WL, Yuan Y, Yuncu A, Zafar AA, Zallo A, Zeng Y, Zeng Z, Zhang BX, Zhang BY, Zhang C, Zhang CC, Zhang DH, Zhang HH, Zhang HY, Zhang J, Zhang JJ, Zhang JL, Zhang JQ, Zhang JW, Zhang JY, Zhang JZ, Zhang K, Zhang L, Zhang SQ, Zhang XY, Zhang Y, Zhang YH, Zhang YN, Zhang YT, Zhang Y, Zhang ZH, Zhang ZP, Zhang ZY, Zhao G, Zhao JW, Zhao JY, Zhao JZ, Zhao L, Zhao L, Zhao MG, Zhao Q, Zhao QW, Zhao SJ, Zhao TC, Zhao YB, Zhao ZG, Zhemchugov A, Zheng B, Zheng JP, Zheng WJ, Zheng YH, Zhong B, Zhou L, Zhou X, Zhou XK, Zhou XR, Zhou XY, Zhu K, Zhu KJ, Zhu S, Zhu SH, Zhu XL, Zhu YC, Zhu YS, Zhu ZA, Zhuang J, Zotti L, Zou BS, Zou JH; BESIII Collaboration.

Phys Rev Lett. 2016 Jun 24;116(25):251802. doi: 10.1103/PhysRevLett.116.251802. Epub 2016 Jun 21.

48.

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.

Clark PG, Vieira LC, Tallant C, Fedorov O, Singleton DC, Rogers CM, Monteiro OP, Bennett JM, Baronio R, Müller S, Daniels DL, Méndez J, Knapp S, Brennan PE, Dixon DJ.

Angew Chem Weinheim Bergstr Ger. 2015 May 18;127(21):6315-6319. Epub 2015 Apr 13.

49.

BET inhibition as a new strategy for the treatment of gastric cancer.

Montenegro RC, Clark PG, Howarth A, Wan X, Ceroni A, Siejka P, Nunez-Alonso GA, Monteiro O, Rogers C, Gamble V, Burbano R, Brennan PE, Tallant C, Ebner D, Fedorov O, O'Neill E, Knapp S, Dixon D, Müller S.

Oncotarget. 2016 Jul 12;7(28):43997-44012. doi: 10.18632/oncotarget.9766.

50.

Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk.

Sdelci S, Lardeau CH, Tallant C, Klepsch F, Klaiber B, Bennett J, Rathert P, Schuster M, Penz T, Fedorov O, Superti-Furga G, Bock C, Zuber J, Huber KV, Knapp S, Müller S, Kubicek S.

Nat Chem Biol. 2016 Jul;12(7):504-10. doi: 10.1038/nchembio.2080. Epub 2016 May 9.

PMID:
27159579

Supplemental Content

Loading ...
Support Center