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Items: 1 to 50 of 74

1.

Larotrectinib, a highly selective tropomyosin receptor kinase (TRK) inhibitor for the treatment of TRK fusion cancer.

Federman N, McDermott R.

Expert Rev Clin Pharmacol. 2019 Sep 10:1-9. doi: 10.1080/17512433.2019.1661775. [Epub ahead of print]

PMID:
31469968
2.

A Phase 2, International, Multicenter, Open-label Clinical Trial of Subcutaneous Tbo-Filgrastim in Pediatric Patients With Solid Tumors Undergoing Myelosuppressive Chemotherapy.

Federman N, Dragomir MD, Kizyma Z, Roganovic J, Bias P, Lammerich A, Ben Arie ZR, Zou L, Hoehn G, Buchner A.

J Pediatr Hematol Oncol. 2019 Jul 3. doi: 10.1097/MPH.0000000000001542. [Epub ahead of print]

PMID:
31274668
3.

Is polycystic kidney disease associated with malignancy in children?

Friend BD, Wolfe Schneider K, Garrington T, Truscott L, Martinez-Agosto JA, Venick RS, Tsai Chambers E, Weng P, Farmer DG, Chang VY, Federman N.

Mol Genet Genomic Med. 2019 Jul;7(7):e00725. doi: 10.1002/mgg3.725. Epub 2019 Jun 14.

4.

Pathologic Response to Neoadjuvant Therapy is Associated With Improved Long-term Survival in High-risk Primary Localized Malignant Peripheral Nerve Sheath Tumors.

Shurell-Linehan E, DiPardo BJ, Elliott IA, Graham DS, Eckardt MA, Dry SM, Nelson SD, Singh AS, Kalbasi A, Federman N, Bernthal NM, Eilber FC.

Am J Clin Oncol. 2019 May;42(5):426-431. doi: 10.1097/COC.0000000000000536.

PMID:
30913092
5.

A Mobile-Based Mindfulness and Social Support Program for Adolescents and Young Adults With Sarcoma: Development and Pilot Testing.

Donovan E, Martin SR, Seidman LC, Zeltzer LK, Cousineau TM, Payne LA, Trant M, Weiman M, Knoll M, Federman NC.

JMIR Mhealth Uhealth. 2019 Mar 18;7(3):e10921. doi: 10.2196/10921.

6.

TRK Fusion Cancers in Children: A Clinical Review and Recommendations for Screening.

Albert CM, Davis JL, Federman N, Casanova M, Laetsch TW.

J Clin Oncol. 2019 Feb 20;37(6):513-524. doi: 10.1200/JCO.18.00573. Epub 2018 Dec 28.

PMID:
30592640
7.

CaMKII Isoforms in Learning and Memory: Localization and Function.

Zalcman G, Federman N, Romano A.

Front Mol Neurosci. 2018 Dec 4;11:445. doi: 10.3389/fnmol.2018.00445. eCollection 2018. Review.

8.

Fetal programming and Wilms tumor.

Heck JE, He D, Janzen C, Federman N, Olsen J, Ritz B, Hansen J.

Pediatr Blood Cancer. 2019 Jan;66(1):e27461. doi: 10.1002/pbc.27461. Epub 2018 Sep 25.

PMID:
30255546
9.

The use of neoadjuvant larotrectinib in the management of children with locally advanced TRK fusion sarcomas.

DuBois SG, Laetsch TW, Federman N, Turpin BK, Albert CM, Nagasubramanian R, Anderson ME, Davis JL, Qamoos HE, Reynolds ME, Cruickshank S, Cox MC, Hawkins DS, Mascarenhas L, Pappo AS.

Cancer. 2018 Nov 1;124(21):4241-4247. doi: 10.1002/cncr.31701. Epub 2018 Sep 11.

10.

Sustained CaMKII Delta Gene Expression Is Specifically Required for Long-Lasting Memories in Mice.

Zalcman G, Federman N, Fiszbein A, de la Fuente V, Ameneiro L, Schor I, Romano A.

Mol Neurobiol. 2019 Feb;56(2):1437-1450. doi: 10.1007/s12035-018-1144-3. Epub 2018 Jun 9.

PMID:
29948945
11.

The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma.

Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Braas D, Go J, Graeber TG, Parlati F, Demo S, Li R, Walser TC, Gricowski M, Shuman R, Ibarra J, Fridman D, Phelps ME, Badran K, St John M, Bernthal NM, Federman N, Yanagawa J, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB.

Cancer Cell. 2018 May 14;33(5):905-921.e5. doi: 10.1016/j.ccell.2018.04.002.

12.

Long-term Outcomes With Ifosfamide-based Hypofractionated Preoperative Chemoradiotherapy for Extremity Soft Tissue Sarcomas.

Pennington JD, Eilber FC, Eilber FR, Singh AS, Reed JP, Chmielowski B, Eckardt JJ, Bukata SV, Bernthal NM, Federman N, Nelson SD, Dry SM, Wang PC, Luu M, Selch MT, Steinberg ML, Kalbasi A, Kamrava M.

Am J Clin Oncol. 2018 Dec;41(12):1154-1161. doi: 10.1097/COC.0000000000000443.

PMID:
29664796
13.

Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study.

Laetsch TW, DuBois SG, Mascarenhas L, Turpin B, Federman N, Albert CM, Nagasubramanian R, Davis JL, Rudzinski E, Feraco AM, Tuch BB, Ebata KT, Reynolds M, Smith S, Cruickshank S, Cox MC, Pappo AS, Hawkins DS.

Lancet Oncol. 2018 May;19(5):705-714. doi: 10.1016/S1470-2045(18)30119-0. Epub 2018 Mar 29. Erratum in: Lancet Oncol. 2018 May;19(5):e229.

14.

Is Core Needle Biopsy Reliable in Differentiating Between Aggressive Benign and Malignant Radiolucent Bone Tumors?

Hegde V, Burke ZDC, Park HY, Zoller SD, Johansen D, Kelley BV, Levine B, Motamedi K, Federman NC, Seeger LL, Nelson SD, Bernthal NM.

Clin Orthop Relat Res. 2018 Mar;476(3):568-577. doi: 10.1007/s11999.0000000000000062.

15.

Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.

Drilon A, Laetsch TW, Kummar S, DuBois SG, Lassen UN, Demetri GD, Nathenson M, Doebele RC, Farago AF, Pappo AS, Turpin B, Dowlati A, Brose MS, Mascarenhas L, Federman N, Berlin J, El-Deiry WS, Baik C, Deeken J, Boni V, Nagasubramanian R, Taylor M, Rudzinski ER, Meric-Bernstam F, Sohal DPS, Ma PC, Raez LE, Hechtman JF, Benayed R, Ladanyi M, Tuch BB, Ebata K, Cruickshank S, Ku NC, Cox MC, Hawkins DS, Hong DS, Hyman DM.

N Engl J Med. 2018 Feb 22;378(8):731-739. doi: 10.1056/NEJMoa1714448.

16.

Alveolar soft part sarcoma in children and young adults: A report of 69 cases.

Flores RJ, Harrison DJ, Federman NC, Furman WL, Huh WW, Broaddus EG, Okcu MF, Venkatramani R.

Pediatr Blood Cancer. 2018 May;65(5):e26953. doi: 10.1002/pbc.26953. Epub 2018 Jan 19.

PMID:
29350467
17.

Fatal orthotopic liver transplant organ rejection induced by a checkpoint inhibitor in two patients with refractory, metastatic hepatocellular carcinoma.

Friend BD, Venick RS, McDiarmid SV, Zhou X, Naini B, Wang H, Farmer DG, Busuttil RW, Federman N.

Pediatr Blood Cancer. 2017 Dec;64(12). doi: 10.1002/pbc.26682. Epub 2017 Jun 23.

PMID:
28643391
18.

Rexin-G®, a tumor-targeted retrovector for malignant peripheral nerve sheath tumor: A case report.

Kim S, Federman N, Gordon EM, Hall FL, Chawla SP.

Mol Clin Oncol. 2017 Jun;6(6):861-865. doi: 10.3892/mco.2017.1231. Epub 2017 Apr 28.

19.

Infiltration of CD8 T Cells and Expression of PD-1 and PD-L1 in Synovial Sarcoma.

Nowicki TS, Akiyama R, Huang RR, Shintaku IP, Wang X, Tumeh PC, Singh A, Chmielowski B, Denny C, Federman N, Ribas A.

Cancer Immunol Res. 2017 Feb;5(2):118-126. doi: 10.1158/2326-6066.CIR-16-0148. Epub 2016 Dec 30.

20.

Clinical Factors That Affect the Establishment of Soft Tissue Sarcoma Patient-Derived Orthotopic Xenografts: A University of California, Los Angeles, Sarcoma Program Prospective Clinical Trial.

Russell TA, Eckardt MA, Murakami T, Elliott IA, Kawaguchi K, Kiyuna T, Igarashi K, Li Y, Crompton JG, Graham DS, Dry SM, Bernthal N, Yanagawa J, Kalbasi A, Federman N, Chmielowski B, Singh AS, Hoffman RM, Eilber FC.

JCO Precis Oncol. 2017;2017. doi: 10.1200/PO.17.00071. Epub 2017 Aug 4.

21.

Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug.

Murakami T, Igarashi K, Kawaguchi K, Kiyuna T, Zhang Y, Zhao M, Hiroshima Y, Nelson SD, Dry SM, Li Y, Yanagawa J, Russell T, Federman N, Singh A, Elliott I, Matsuyama R, Chishima T, Tanaka K, Endo I, Eilber FC, Hoffman RM.

Oncotarget. 2017 Jan 31;8(5):8035-8042. doi: 10.18632/oncotarget.14040.

22.

Current management of aneurysmal bone cysts.

Park HY, Yang SK, Sheppard WL, Hegde V, Zoller SD, Nelson SD, Federman N, Bernthal NM.

Curr Rev Musculoskelet Med. 2016 Dec;9(4):435-444. Review.

23.

Heterozygous Che-1 KO mice show deficiencies in object recognition memory persistence.

Zalcman G, Corbi N, Di Certo MG, Mattei E, Federman N, Romano A.

Neurosci Lett. 2016 Oct 6;632:169-74. doi: 10.1016/j.neulet.2016.08.055. Epub 2016 Aug 31.

PMID:
27589891
24.

Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes.

Shurell E, Singh AS, Crompton JG, Jensen S, Li Y, Dry S, Nelson S, Chmielowski B, Bernthal N, Federman N, Tumeh P, Eilber FC.

Oncotarget. 2016 Sep 27;7(39):64300-64308. doi: 10.18632/oncotarget.11734.

25.

Novel association of familial testicular germ cell tumor and autosomal dominant polycystic kidney disease with PKD1 mutation.

Truscott L, Gell J, Chang VY, Lee H, Strom SP, Pillai R, Sisk A, Martinez-Agosto JA, Anderson M, Federman N.

Pediatr Blood Cancer. 2017 Jan;64(1):100-102. doi: 10.1002/pbc.26197. Epub 2016 Aug 31.

26.

Sclerostin expression in skeletal sarcomas.

Shen J, Meyers CA, Shrestha S, Singh A, LaChaud G, Nguyen V, Asatrian G, Federman N, Bernthal N, Eilber FC, Dry SM, Ting K, Soo C, James AW.

Hum Pathol. 2016 Dec;58:24-34. doi: 10.1016/j.humpath.2016.07.016. Epub 2016 Aug 3.

27.

Labeling the Stroma of a Patient-Derived Orthotopic Xenograft (PDOX) Mouse Model of Undifferentiated Pleomorphic Soft-Tissue Sarcoma With Red Fluorescent Protein for Rapid Non-Invasive Imaging for Drug Screening.

Kiyuna T, Murakami T, Tome Y, Igarashi K, Kawaguchi K, Russell T, Eckardt MA, Crompton J, Singh A, Bernthal N, Bukata S, Federman N, Kanaya F, Eilber FC, Hoffman RM.

J Cell Biochem. 2017 Feb;118(2):361-365. doi: 10.1002/jcb.25643. Epub 2016 Jul 12.

28.

Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model.

Murakami T, Singh AS, Kiyuna T, Dry SM, Li Y, James AW, Igarashi K, Kawaguchi K, DeLong JC, Zhang Y, Hiroshima Y, Russell T, Eckardt MA, Yanagawa J, Federman N, Matsuyama R, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM.

Oncotarget. 2016 Jul 26;7(30):47556-47564. doi: 10.18632/oncotarget.9879.

29.

Prospective immunotherapies in childhood sarcomas: PD1/PDL1 blockade in combination with tumor vaccines.

Nowicki TS, Anderson JL, Federman N.

Pediatr Res. 2016 Mar;79(3):371-7. doi: 10.1038/pr.2015.246. Epub 2015 Nov 23. Review.

PMID:
26595537
30.

NF-κB transcription factor role in consolidation and reconsolidation of persistent memories.

de la Fuente V, Federman N, Zalcman G, Salles A, Freudenthal R, Romano A.

Front Mol Neurosci. 2015 Sep 9;8:50. doi: 10.3389/fnmol.2015.00050. eCollection 2015. Review.

31.

Evaluation of In Vitro Activity of the Class I PI3K Inhibitor Buparlisib (BKM120) in Pediatric Bone and Soft Tissue Sarcomas.

Anderson JL, Park A, Akiyama R, Tap WD, Denny CT, Federman N.

PLoS One. 2015 Sep 24;10(9):e0133610. doi: 10.1371/journal.pone.0133610. eCollection 2015.

32.

Nuclear factor kappa B-dependent Zif268 expression in hippocampus is required for recognition memory in mice.

Zalcman G, Federman N, de la Fuente V, Romano A.

Neurobiol Learn Mem. 2015 Mar;119:10-7. doi: 10.1016/j.nlm.2014.12.013. Epub 2015 Jan 7.

PMID:
25576790
33.

Gender dimorphism and age of onset in malignant peripheral nerve sheath tumor preclinical models and human patients.

Shurell E, Tran LM, Nakashima J, Smith KB, Tam BM, Li Y, Dry SM, Federman N, Tap WD, Wu H, Eilber FC.

BMC Cancer. 2014 Nov 15;14:827. doi: 10.1186/1471-2407-14-827.

34.

Risk stratification of patients undergoing pulmonary metastasectomy for soft tissue and bone sarcomas.

Lin AY, Kotova S, Yanagawa J, Elbuluk O, Wang G, Kar N, Elashoff D, Grogan T, Cameron RB, Singh A, Chmielowski B, Federman N, Nelson SD, Lee P, Eilber FC, Lee JM.

J Thorac Cardiovasc Surg. 2015 Jan;149(1):85-92. doi: 10.1016/j.jtcvs.2014.09.039. Epub 2014 Sep 18.

35.

Protein degradation by ubiquitin-proteasome system in formation and labilization of contextual conditioning memory.

Sol Fustiñana M, de la Fuente V, Federman N, Freudenthal R, Romano A.

Learn Mem. 2014 Aug 18;21(9):478-87. doi: 10.1101/lm.035998.114. Print 2014 Sep. Erratum in: Learn Mem. 2014 Nov;21(11):646.

36.

Calcineurin phosphatase as a negative regulator of fear memory in hippocampus: control on nuclear factor-κB signaling in consolidation and reconsolidation.

de la Fuente V, Federman N, Fustiñana MS, Zalcman G, Romano A.

Hippocampus. 2014 Dec;24(12):1549-61. doi: 10.1002/hipo.22334. Epub 2014 Aug 13.

PMID:
25043904
37.

Epigenetic mechanisms and memory strength: a comparative study.

Federman N, Zalcman G, de la Fuente V, Fustiñana MS, Romano A.

J Physiol Paris. 2014 Sep-Dec;108(4-6):278-85. doi: 10.1016/j.jphysparis.2014.06.003. Epub 2014 Jun 28. Review.

PMID:
24978317
38.

Congenital Extrarenal Extra-Central Nervous System Malignant Rhabdoid Tumor of the Upper Extremity: A Case Report.

Frank JM, Eckardt JJ, Nelson SD, Seeger L, Federman N.

JBJS Case Connect. 2013 Dec 11;3(4 Suppl 6):e124-e5. doi: 10.2106/JBJS.CC.M.00034. No abstract available.

PMID:
29252280
39.

Safety and efficacy of stereotactic body radiation therapy in the treatment of pulmonary metastases from high grade sarcoma.

Mehta N, Selch M, Wang PC, Federman N, Lee JM, Eilber FC, Chmielowski B, Agazaryan N, Steinberg M, Lee P.

Sarcoma. 2013;2013:360214. doi: 10.1155/2013/360214. Epub 2013 Oct 1.

40.

Giant cell tumor of bone in childhood: clinical aspects and novel therapeutic targets.

Federman N, Brien EW, Narasimhan V, Dry SM, Sodhi M, Chawla SP.

Paediatr Drugs. 2014 Feb;16(1):21-8. doi: 10.1007/s40272-013-0051-3.

PMID:
24114694
41.

An engineered anti-CA19-9 cys-diabody for positron emission tomography imaging of pancreatic cancer and targeting of polymerized liposomal nanoparticles.

Girgis MD, Federman N, Rochefort MM, McCabe KE, Wu AM, Nagy JO, Denny C, Tomlinson JS.

J Surg Res. 2013 Nov;185(1):45-55. doi: 10.1016/j.jss.2013.05.095. Epub 2013 Jun 19.

42.

Nuclear factor κB-dependent histone acetylation is specifically involved in persistent forms of memory.

Federman N, de la Fuente V, Zalcman G, Corbi N, Onori A, Passananti C, Romano A.

J Neurosci. 2013 Apr 24;33(17):7603-14. doi: 10.1523/JNEUROSCI.4181-12.2013.

43.

Image-guided percutaneous core needle biopsy of musculoskeletal tumors in children.

Mitton B, Seeger LL, Eckardt MA, Motamedi K, Eilber FC, Nelson SD, Eckardt JJ, Federman N.

J Pediatr Hematol Oncol. 2014 Jul;36(5):337-41. doi: 10.1097/MPH.0b013e3182880de0.

44.

A child with gemcitabine-induced severe radiation recall myositis resulting in a compartment syndrome.

Eckardt MA, Bean A, Selch MT, Federman N.

J Pediatr Hematol Oncol. 2013 Mar;35(2):156-61. doi: 10.1097/MPH.0b013e31827e4c28.

PMID:
23274380
45.

Ventricular fibrillation induced by spontaneous hypothermia in a patient with early repolarization syndrome.

Federman NJ, Mechulan A, Klein GJ, Krahn AD.

J Cardiovasc Electrophysiol. 2013 May;24(5):586-8. doi: 10.1111/jce.12030. Epub 2012 Nov 9.

PMID:
23140469
46.

A single-institution retrospective cases series of childhood undifferentiated embryonal liver sarcoma (UELS): success of combined therapy and the use of orthotopic liver transplant.

Plant AS, Busuttil RW, Rana A, Nelson SD, Auerbach M, Federman NC.

J Pediatr Hematol Oncol. 2013 Aug;35(6):451-5. doi: 10.1097/MPH.0b013e318271c948.

PMID:
23138115
47.

Clinical trial end points for assessing efficacy of novel therapies for soft-tissue sarcomas.

Chmielowski B, Federman N, Tap WD.

Expert Rev Anticancer Ther. 2012 Sep;12(9):1217-28. doi: 10.1586/era.12.100. Review.

PMID:
23098121
48.

Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor.

Federman N, Chan J, Nagy JO, Landaw EM, McCabe K, Wu AM, Triche T, Kang H, Liu B, Marks JD, Denny CT.

Sarcoma. 2012;2012:126906. Epub 2012 Sep 11.

49.

Whole exome sequencing of pediatric gastric adenocarcinoma reveals an atypical presentation of Li-Fraumeni syndrome.

Chang VY, Federman N, Martinez-Agosto J, Tatishchev SF, Nelson SF.

Pediatr Blood Cancer. 2013 Apr;60(4):570-4. doi: 10.1002/pbc.24316. Epub 2012 Sep 26.

50.

Reconsolidation involves histone acetylation depending on the strength of the memory.

Federman N, Fustiñana MS, Romano A.

Neuroscience. 2012 Sep 6;219:145-56. doi: 10.1016/j.neuroscience.2012.05.057. Epub 2012 Jun 1.

PMID:
22659565

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