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Items: 1 to 50 of 77

1.

AAV gene delivery to the spinal cord: serotypes, methods, candidate diseases, and clinical trials.

Hardcastle N, Boulis NM, Federici T.

Expert Opin Biol Ther. 2018 Mar;18(3):293-307. doi: 10.1080/14712598.2018.1416089. Epub 2017 Dec 18. Review.

PMID:
29249183
2.

Peripheral blood detection of systemic graft-specific xeno-antibodies following transplantation of human neural progenitor cells into the porcine spinal cord.

Lamanna JJ, Gutierrez J, Espinosa JR, Wagner J, Urquia LN, Moreton C, Victor Hurtig C, Tora M, Kirk AD, Federici T, Boulis NM.

J Clin Neurosci. 2018 Feb;48:173-180. doi: 10.1016/j.jocn.2017.10.033. Epub 2017 Oct 28.

PMID:
29089163
3.

Ferumoxytol Labeling of Human Neural Progenitor Cells for Diagnostic Cellular Tracking in the Porcine Spinal Cord with Magnetic Resonance Imaging.

Lamanna JJ, Gutierrez J, Urquia LN, Hurtig CV, Amador E, Grin N, Svendsen CN, Federici T, Oshinski JN, Boulis NM.

Stem Cells Transl Med. 2017 Jan;6(1):139-150. doi: 10.5966/sctm.2015-0422. Epub 2016 Aug 29.

4.

Magnetic Resonance Imaging-Guided Transplantation of Neural Stem Cells into the Porcine Spinal Cord.

Lamanna JJ, Urquia LN, Hurtig CV, Gutierrez J, Anderson C, Piferi P, Federici T, Oshinski JN, Boulis NM.

Stereotact Funct Neurosurg. 2017;95(1):60-68. doi: 10.1159/000448765. Epub 2017 Jan 28.

5.

Transplantation of spinal cord-derived neural stem cells for ALS: Analysis of phase 1 and 2 trials.

Glass JD, Hertzberg VS, Boulis NM, Riley J, Federici T, Polak M, Bordeau J, Fournier C, Johe K, Hazel T, Cudkowicz M, Atassi N, Borges LF, Rutkove SB, Duell J, Patil PG, Goutman SA, Feldman EL.

Neurology. 2016 Jul 26;87(4):392-400. doi: 10.1212/WNL.0000000000002889. Epub 2016 Jun 29. Erratum in: Neurology. 2017 Aug 1;89(5):521.

6.

Preclinical Validation of Multilevel Intraparenchymal Stem Cell Therapy in the Porcine Spinal Cord.

Gutierrez J, Lamanna JJ, Grin N, Hurtig CV, Miller JH, Riley J, Urquia L, Avalos P, Svendsen CN, Federici T, Boulis NM.

Neurosurgery. 2015 Oct;77(4):604-12; discussion 612. doi: 10.1227/NEU.0000000000000882.

PMID:
26134596
7.

Rational design and engineering of a modified adeno-associated virus (AAV1)-based vector system for enhanced retrograde gene delivery.

Davis AS, Federici T, Ray WC, Boulis NM, O╩╝Connor D, Clark KR, Bartlett JS.

Neurosurgery. 2015 Feb;76(2):216-25; discussion 225. doi: 10.1227/NEU.0000000000000589.

PMID:
25549186
8.

Analysis of graft survival in a trial of stem cell transplant in ALS.

Tadesse T, Gearing M, Senitzer D, Saxe D, Brat DJ, Bray R, Gebel H, Hill C, Boulis N, Riley J, Feldman E, Johe K, Hazel T, Polak M, Bordeau J, Federici T, Glass JD.

Ann Clin Transl Neurol. 2014 Nov;1(11):900-8. doi: 10.1002/acn3.134. Epub 2014 Oct 22.

9.

Translational fidelity of intrathecal delivery of self-complementary AAV9-survival motor neuron 1 for spinal muscular atrophy.

Passini MA, Bu J, Richards AM, Treleaven CM, Sullivan JA, O'Riordan CR, Scaria A, Kells AP, Samaranch L, San Sebastian W, Federici T, Fiandaca MS, Boulis NM, Bankiewicz KS, Shihabuddin LS, Cheng SH.

Hum Gene Ther. 2014 Jul;25(7):619-30. doi: 10.1089/hum.2014.011. Epub 2014 Apr 28.

PMID:
24617515
10.

Intraspinal neural stem cell transplantation in amyotrophic lateral sclerosis: phase 1 trial outcomes.

Feldman EL, Boulis NM, Hur J, Johe K, Rutkove SB, Federici T, Polak M, Bordeau J, Sakowski SA, Glass JD.

Ann Neurol. 2014 Mar;75(3):363-73. doi: 10.1002/ana.24113. Epub 2014 Mar 7.

11.

Intraspinal stem cell transplantation in amyotrophic lateral sclerosis: a phase I trial, cervical microinjection, and final surgical safety outcomes.

Riley J, Glass J, Feldman EL, Polak M, Bordeau J, Federici T, Johe K, Boulis NM.

Neurosurgery. 2014 Jan;74(1):77-87. doi: 10.1227/NEU.0000000000000156.

PMID:
24018694
12.

Regulated neuronal neuromodulation via spinal cord expression of the gene for the inwardly rectifying potassium channel 2.1 (Kir2.1).

Boulis NM, Handy CR, Krudy CA, Donnelly EM, Federici T, Franz CK, Barrow EM, Teng Q, Kumar P, Cress D.

Neurosurgery. 2013 Apr;72(4):653-61; discussion 661. doi: 10.1227/NEU.0b013e318283f59a.

PMID:
23277370
13.

Surgical technique for spinal cord delivery of therapies: demonstration of procedure in gottingen minipigs.

Federici T, Hurtig CV, Burks KL, Riley JP, Krishna V, Miller BA, Sribnick EA, Miller JH, Grin N, Lamanna JJ, Boulis NM.

J Vis Exp. 2012 Dec 7;(70):e4371. doi: 10.3791/4371.

14.

Circulating vascular endothelial growth factor in childhood solid tumors: plasma and serum measurements.

Schiavetti A, Ingrosso A, Antenucci A, Federici T, Megaro G, De Luca L, Conti L.

Anticancer Res. 2012 Aug;32(8):3565-9.

PMID:
22843947
15.

Intraspinal stem cell transplantation in amyotrophic lateral sclerosis: a phase I safety trial, technical note, and lumbar safety outcomes.

Riley J, Federici T, Polak M, Kelly C, Glass J, Raore B, Taub J, Kesner V, Feldman EL, Boulis NM.

Neurosurgery. 2012 Aug;71(2):405-16; discussion 416. doi: 10.1227/NEU.0b013e31825ca05f.

PMID:
22565043
16.

Lumbar intraspinal injection of neural stem cells in patients with amyotrophic lateral sclerosis: results of a phase I trial in 12 patients.

Glass JD, Boulis NM, Johe K, Rutkove SB, Federici T, Polak M, Kelly C, Feldman EL.

Stem Cells. 2012 Jun;30(6):1144-51. doi: 10.1002/stem.1079.

17.

Characterization of a murine model of SMA.

Donnelly EM, Quach ET, Hillery TM, Heeke BL, Snyder BR, Handy CR, O'Connor DM, Boulis NM, Federici T.

Neurobiol Dis. 2012 Mar;45(3):992-8. doi: 10.1016/j.nbd.2011.12.018. Epub 2011 Dec 14.

PMID:
22198571
18.

Translational stem cell therapy for amyotrophic lateral sclerosis.

Boulis NM, Federici T, Glass JD, Lunn JS, Sakowski SA, Feldman EL.

Nat Rev Neurol. 2011 Dec 13;8(3):172-6. doi: 10.1038/nrneurol.2011.191. Review.

PMID:
22158518
19.

Robust spinal motor neuron transduction following intrathecal delivery of AAV9 in pigs.

Federici T, Taub JS, Baum GR, Gray SJ, Grieger JC, Matthews KA, Handy CR, Passini MA, Samulski RJ, Boulis NM.

Gene Ther. 2012 Aug;19(8):852-9. doi: 10.1038/gt.2011.130. Epub 2011 Sep 15.

PMID:
21918551
20.

Gene therapy for amyotrophic lateral sclerosis.

Federici T, Boulis NM.

Neurobiol Dis. 2012 Nov;48(2):236-42. doi: 10.1016/j.nbd.2011.08.018. Epub 2011 Aug 25. Review.

PMID:
21889591
21.

Intramuscular administration of a VEGF zinc finger transcription factor activator (VEGF-ZFP-TF) improves functional outcomes in SOD1 rats.

Kliem MA, Heeke BL, Franz CK, Radovitskiy I, Raore B, Barrow E, Snyder BR, Federici T, Kaye Spratt S, Boulis NM.

Amyotroph Lateral Scler. 2011 Sep;12(5):331-9. doi: 10.3109/17482968.2011.574142. Epub 2011 Aug 24.

PMID:
21864053
22.

Assessment of hippocampal adeno-associated viral vector gene delivery via frameless stereotaxis in a nonhuman primate.

Leung CH, Kliem MA, Heeke BL, McPhee SW, Federici T, Snyder BR, Boulis NM.

Stereotact Funct Neurosurg. 2011;89(5):275-85. doi: 10.1159/000328265. Epub 2011 Aug 18.

23.

The non-antibiotic properties of tetracyclines: clinical potential in ophthalmic disease.

Federici TJ.

Pharmacol Res. 2011 Dec;64(6):614-23. doi: 10.1016/j.phrs.2011.06.013. Epub 2011 Jun 21. Review.

PMID:
21843641
24.

Pharmacokinetics of triamcinolone acetonide for the treatment of macular edema.

Yilmaz T, Cordero-Coma M, Federici TJ.

Expert Opin Drug Metab Toxicol. 2011 Oct;7(10):1327-35. doi: 10.1517/17425255.2011.606215. Epub 2011 Jul 27. Review.

PMID:
21790508
25.

Pain in amyotrophic lateral sclerosis: a neglected aspect of disease.

Handy CR, Krudy C, Boulis N, Federici T.

Neurol Res Int. 2011;2011:403808. doi: 10.1155/2011/403808. Epub 2011 May 3.

26.

Allergic proctocolitis refractory to maternal hypoallergenic diet in exclusively breast-fed infants: a clinical observation.

Lucarelli S, Di Nardo G, Lastrucci G, D'Alfonso Y, Marcheggiano A, Federici T, Frediani S, Frediani T, Cucchiara S.

BMC Gastroenterol. 2011 Jul 16;11:82. doi: 10.1186/1471-230X-11-82.

27.

Surgical approach and safety of spinal cord stem cell transplantation.

Boulis N, Federici T.

Neurosurgery. 2011 Feb;68(2):E599-600. doi: 10.1227/NEU.0b013e3182095e2e. No abstract available.

PMID:
21654562
28.

Platform and cannula design improvements for spinal cord therapeutics delivery.

Riley JP, Raore B, Taub JS, Federici T, Boulis NM.

Neurosurgery. 2011 Dec;69(2 Suppl Operative):ons147-54; discussion ons155. doi: 10.1227/NEU.0b013e3182195680.

PMID:
21471842
29.

Comparison of adeno-associated viral vector serotypes for spinal cord and motor neuron gene delivery.

Snyder BR, Gray SJ, Quach ET, Huang JW, Leung CH, Samulski RJ, Boulis NM, Federici T.

Hum Gene Ther. 2011 Sep;22(9):1129-35. doi: 10.1089/hum.2011.008. Epub 2011 Jul 25.

PMID:
21443428
30.

Stem cell technology for the study and treatment of motor neuron diseases.

Lunn JS, Sakowski SA, Federici T, Glass JD, Boulis NM, Feldman EL.

Regen Med. 2011 Mar;6(2):201-13. doi: 10.2217/rme.11.6. Review. Erratum in: Regen Med. 2011 Jul;6(4):536.

31.

Cervical multilevel intraspinal stem cell therapy: assessment of surgical risks in Gottingen minipigs.

Raore B, Federici T, Taub J, Wu MC, Riley J, Franz CK, Kliem MA, Snyder B, Feldman EL, Johe K, Boulis NM.

Spine (Phila Pa 1976). 2011 Feb 1;36(3):E164-71. doi: 10.1097/BRS.0b013e3181d77a47.

PMID:
21099736
32.

Preclinical safety validation of a stabilized viral vector direct injection approach to the cervical spinal cord.

Federici T, Riley J, Park J, Bain M, Boulis N.

Clin Transl Sci. 2009 Apr;2(2):165-7. doi: 10.1111/j.1752-8062.2008.00084.x.

33.

Viral vector-mediated gene transfer for CNS disease.

Snyder BR, Boulis NM, Federici T.

Expert Opin Biol Ther. 2010 Mar;10(3):381-94. doi: 10.1517/14712590903514074. Review.

PMID:
20132059
34.

Synemin isoforms in astroglial and neuronal cells from human central nervous system.

Izmiryan A, Peltekian E, Federici T, Paulin D, Li ZL, Xue ZG.

Neurochem Res. 2010 Jun;35(6):881-7. doi: 10.1007/s11064-009-0111-9. Epub 2009 Dec 19. Erratum in: Neurochem Res. 2011 Jun;36(6):1145. Federici, T [added].

PMID:
20024673
35.
36.

Cervical spinal cord therapeutics delivery: preclinical safety validation of a stabilized microinjection platform.

Riley J, Federici T, Park J, Suzuki M, Franz CK, Tork C, McHugh J, Teng Q, Svendsen C, Boulis NM.

Neurosurgery. 2009 Oct;65(4):754-61; discussion 761-2. doi: 10.1227/01.NEU.0000343524.45387.9E.

37.

A conditioning lesion provides selective protection in a rat model of Amyotrophic Lateral Sclerosis.

Franz CK, Quach ET, Krudy CA, Federici T, Kliem MA, Snyder BR, Raore B, Boulis NM.

PLoS One. 2009 Oct 6;4(10):e7357. doi: 10.1371/journal.pone.0007357.

38.

Optogenetic neuromodulation.

Henderson JM, Federici T, Boulis N.

Neurosurgery. 2009 May;64(5):796-804; discussion 804. doi: 10.1227/01.NEU.0000339171.87593.6A. Review.

PMID:
19404144
39.

Comparative analysis of HIV-1-based lentiviral vectors bearing lyssavirus glycoproteins for neuronal gene transfer.

Federici T, Kutner R, Zhang XY, Kuroda H, Tordo N, Boulis NM, Reiser J.

Genet Vaccines Ther. 2009 Jan 13;7:1. doi: 10.1186/1479-0556-7-1.

40.

Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS.

Franz CK, Federici T, Yang J, Backus C, Oh SS, Teng Q, Carlton E, Bishop KM, Gasmi M, Bartus RT, Feldman EL, Boulis NM.

Neurobiol Dis. 2009 Mar;33(3):473-81. doi: 10.1016/j.nbd.2008.12.003. Epub 2008 Dec 24.

PMID:
19135533
41.

Fusion of the tetanus toxin C fragment binding domain and Bcl-xL for protection of peripheral nerve neurons.

Carlton E, Teng Q, Federici T, Yang J, Riley J, Boulis NM.

Neurosurgery. 2008 Dec;63(6):1175-82; discussion 1182-4. doi: 10.1227/01.NEU.0000334415.45003.EA. Erratum in: Neurosurgery. 2009 Mar;64(3):539.

PMID:
19057331
42.

Infliximab for pediatric ulcerative colitis: a retrospective Italian multicenter study.

Cucchiara S, Romeo E, Viola F, Cottone M, Fontana M, Lombardi G, Rutigliano V, de'Angelis GL, Federici T.

Dig Liver Dis. 2008 Jul;40 Suppl 2:S260-4. doi: 10.1016/S1590-8658(08)60535-6.

PMID:
18598998
43.

Ribonucleic acid interference: the relevance of molecular targeting and therapeutics to neurosurgical practice.

Federici T, Boulis NM.

Clin Neurosurg. 2007;54:110-7. Review. No abstract available.

PMID:
18504906
44.

Targeted spinal cord therapeutics delivery: stabilized platform and microelectrode recording guidance validation.

Riley J, Butler J, Baker KB, McClelland S 3rd, Teng Q, Yang J, Garrity-Moses M, Federici T, Boulis NM.

Stereotact Funct Neurosurg. 2008;86(2):67-74. Epub 2007 Dec 12.

PMID:
18073518
45.

Leuprolide acetate and central retinal vein occlusion.

Federici TJ.

Ophthalmic Surg Lasers Imaging. 2007 Nov-Dec;38(6):497-9.

PMID:
18050813
46.

Gene therapy for peripheral nervous system diseases.

Federici T, Boulis N.

Curr Gene Ther. 2007 Aug;7(4):239-48. Review.

PMID:
17969557
47.

Bilateral orbital infarction, ophthalmic artery occlusion, and cherry-red spot.

Federici TJ.

Arch Ophthalmol. 2007 Oct;125(10):1441; author reply 1441-2. No abstract available.

PMID:
17923568
48.

Reversible unilateral nigrostriatal pathway inhibition induced through expression of adenovirus-mediated clostridial light chain gene in the substantia nigra.

Yang J, Teng Q, Garrity-Moses ME, McClelland S 3rd, Federici T, Carlton E, Riley J, Boulis NM.

Neuromolecular Med. 2007;9(3):276-84.

PMID:
17914186
49.

Optical coherence tomography reveals retinal degeneration from persistent submacular fluid after pneumatic retinopexy for rhegmatogenous retinal detachment.

Federici TJ, Willson RL, Gitter KA.

Retin Cases Brief Rep. 2007 Fall;1(4):241-3. doi: 10.1097/01.iae.0000225743.73046.05.

PMID:
25390990
50.

Choroidal neovascularization following macular surgery.

Federici TJ.

Arch Ophthalmol. 2007 Jun;125(6):856; author reply 857. No abstract available.

PMID:
17563014

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