Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 117

1.

Flavorings-Related Lung Disease: A Brief Review and New Mechanistic Data.

Hubbs AF, Kreiss K, Cummings KJ, Fluharty KL, O'Connell R, Cole A, Dodd TM, Clingerman SM, Flesher JR, Lee R, Pagel S, Battelli LA, Cumpston A, Jackson M, Kashon M, Orandle MS, Fedan JS, Sriram K.

Toxicol Pathol. 2019 Oct 23:192623319879906. doi: 10.1177/0192623319879906. [Epub ahead of print]

PMID:
31645208
2.

Toxicological assessment of dust from sanding micronized copper-treated lumber in vivo.

Sisler JD, Mandler WK, Shaffer J, Lee T, McKinney WG, Battelli LA, Orandle MS, Thomas TA, Castranova VC, Qi C, Porter DW, Andrew ME, Fedan JS, Mercer RR, Qian Y.

J Hazard Mater. 2019 Jul 5;373:630-639. doi: 10.1016/j.jhazmat.2019.02.068. Epub 2019 Mar 31. Erratum in: J Hazard Mater. 2019 Nov 26;:121369.

3.

Comparison of multi-wall carbon nanotube and nitrogen-doped multi-wall carbon nanotube effects on lung function and airway reactivity in rats.

Russ KA, Thompson JA, Kashon M, Porter DW, Friend SA, McKinney W, Fedan JS.

Toxicol Appl Pharmacol. 2019 Feb 1;364:153-163. doi: 10.1016/j.taap.2018.11.004. Epub 2018 Nov 10.

PMID:
30423287
4.

Pulmonary toxicity following acute coexposures to diesel particulate matter and α-quartz crystalline silica in the Sprague-Dawley rat.

Farris BY, Antonini JM, Fedan JS, Mercer RR, Roach KA, Chen BT, Schwegler-Berry D, Kashon ML, Barger MW, Roberts JR.

Inhal Toxicol. 2017 Jun;29(7):322-339. doi: 10.1080/08958378.2017.1361487. Epub 2017 Oct 1.

5.

Altered ion transport in normal human bronchial epithelial cells following exposure to chemically distinct metal welding fume particles.

Fedan JS, Thompson JA, Meighan TG, Zeidler-Erdely PC, Antonini JM.

Toxicol Appl Pharmacol. 2017 Jul 1;326:1-6. doi: 10.1016/j.taap.2017.04.008. Epub 2017 Apr 12.

PMID:
28411035
6.

Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity.

Hubbs AF, Fluharty KL, Edwards RJ, Barnabei JL, Grantham JT, Palmer SM, Kelly F, Sargent LM, Reynolds SH, Mercer RR, Goravanahally MP, Kashon ML, Honaker JC, Jackson MC, Cumpston AM, Goldsmith WT, McKinney W, Fedan JS, Battelli LA, Munro T, Bucklew-Moyers W, McKinstry K, Schwegler-Berry D, Friend S, Knepp AK, Smith SL, Sriram K.

Am J Pathol. 2016 Nov;186(11):2887-2908. doi: 10.1016/j.ajpath.2016.07.018.

7.

Diacetyl and 2,3-pentanedione exposure of human cultured airway epithelial cells: Ion transport effects and metabolism of butter flavoring agents.

Zaccone EJ, Goldsmith WT, Shimko MJ, Wells JR, Schwegler-Berry D, Willard PA, Case SL, Thompson JA, Fedan JS.

Toxicol Appl Pharmacol. 2015 Dec 15;289(3):542-9. doi: 10.1016/j.taap.2015.10.004. Epub 2015 Oct 21.

8.

Nerve growth factor reduces amiloride-sensitive Na+ transport in human airway epithelial cells.

Shimko MJ, Zaccone EJ, Thompson JA, Schwegler-Berry D, Kashon ML, Fedan JS.

Physiol Rep. 2014 Jul 16;2(7). pii: e12073. doi: 10.14814/phy2.12073.

9.

Effects of acute inhalation of aerosols generated during resistance spot welding with mild-steel on pulmonary, vascular and immune responses in rats.

Zeidler-Erdely PC, Meighan TG, Erdely A, Fedan JS, Thompson JA, Bilgesu S, Waugh S, Anderson S, Marshall NB, Afshari A, McKinney W, Frazer DG, Antonini JM.

Inhal Toxicol. 2014 Oct;26(12):697-707. doi: 10.3109/08958378.2014.944287. Epub 2014 Aug 20.

10.

Evaluation of Pulmonary and Systemic Toxicity of Oil Dispersant (COREXIT EC9500A(®)) Following Acute Repeated Inhalation Exposure.

Roberts JR, Anderson SE, Kan H, Krajnak K, Thompson JA, Kenyon A, Goldsmith WT, McKinney W, Frazer DG, Jackson M, Fedan JS.

Environ Health Insights. 2015 Feb 9;8(Suppl 1):63-74. doi: 10.4137/EHI.S15262. eCollection 2014.

11.

Tracheal epithelium cell volume responses to hyperosmolar, isosmolar and hypoosmolar solutions: relation to epithelium-derived relaxing factor (EpDRF) effects.

Fedan JS, Thompson JA, Ismailoglu UB, Jing Y.

Front Physiol. 2013 Oct 11;4:287. doi: 10.3389/fphys.2013.00287. eCollection 2013.

12.

Popcorn flavoring effects on reactivity of rat airways in vivo and in vitro.

Zaccone EJ, Thompson JA, Ponnoth DS, Cumpston AM, Goldsmith WT, Jackson MC, Kashon ML, Frazer DG, Hubbs AF, Shimko MJ, Fedan JS.

J Toxicol Environ Health A. 2013;76(11):669-89. doi: 10.1080/15287394.2013.796302.

13.

Diacetyl increases sensory innervation and substance P production in rat trachea.

Goravanahally MP, Hubbs AF, Fedan JS, Kashon ML, Battelli LA, Mercer RR, Goldsmith WT, Jackson MC, Cumpston A, Frazer DG, Dey RD.

Toxicol Pathol. 2014;42(3):582-90. doi: 10.1177/0192623313493689. Epub 2013 Jul 11.

14.

Respiratory and olfactory cytotoxicity of inhaled 2,3-pentanedione in Sprague-Dawley rats.

Hubbs AF, Cumpston AM, Goldsmith WT, Battelli LA, Kashon ML, Jackson MC, Frazer DG, Fedan JS, Goravanahally MP, Castranova V, Kreiss K, Willard PA, Friend S, Schwegler-Berry D, Fluharty KL, Sriram K.

Am J Pathol. 2012 Sep;181(3):829-44. doi: 10.1016/j.ajpath.2012.05.021. Epub 2012 Aug 13.

15.

Pulmonary effects after acute inhalation of oil dispersant (COREXIT EC9500A) in rats.

Roberts JR, Reynolds JS, Thompson JA, Zaccone EJ, Shimko MJ, Goldsmith WT, Jackson M, McKinney W, Frazer DG, Kenyon A, Kashon ML, Piedimonte G, Castranova V, Fedan JS.

J Toxicol Environ Health A. 2011;74(21):1381-96. doi: 10.1080/15287394.2011.606794.

PMID:
21916744
16.

Lipopolysaccharide increases Na(+),K(+)-pump, but not ENaC, expression in guinea-pig airway epithelium.

Dodrill MW, Beezhold DH, Meighan T, Kashon ML, Fedan JS.

Eur J Pharmacol. 2011 Jan 25;651(1-3):176-86. doi: 10.1016/j.ejphar.2010.10.088. Epub 2010 Nov 27.

PMID:
21114982
17.

Lipopolysaccharide hyperpolarizes guinea pig airway epithelium by increasing the activities of the epithelial Na(+) channel and the Na(+)-K(+) pump.

Dodrill MW, Fedan JS.

Am J Physiol Lung Cell Mol Physiol. 2010 Oct;299(4):L550-8. doi: 10.1152/ajplung.00123.2010. Epub 2010 Jul 16.

18.

Dr R Shiffmann's Asthmador: relevant to our times, or a snake oil remedy?

Fedan JS, Piedimonte G.

Curr Opin Pharmacol. 2010 Jun;10(3):213-7. doi: 10.1016/j.coph.2010.06.005. Epub 2010 Jun 17. No abstract available.

PMID:
20561820
19.

Effects of cytokines on mechanical and epithelial bioelectric responses to methacholine and hyperosmolarity in guinea-pig airways: an in vitro study.

Ismailoglu UB, Scott MR, Fedan JS.

Eur J Pharmacol. 2009 Jun 10;612(1-3):115-21. doi: 10.1016/j.ejphar.2009.04.025. Epub 2009 Apr 19.

PMID:
19383494
20.

Simultaneous measurement of mechanical responses and transepithelial potential difference and resistance, in guinea-pig isolated, perfused trachea using a novel apparatus: pharmacological characterization.

Jing Y, Dowdy JA, Van Scott MR, Fedan JS.

Eur J Pharmacol. 2008 Nov 19;598(1-3):98-103. doi: 10.1016/j.ejphar.2008.09.009. Epub 2008 Sep 22.

PMID:
18835555
21.

Hyperosmolarity-induced dilation and epithelial bioelectric responses of guinea pig trachea in vitro: role of kinase signaling.

Jing Y, Dowdy JA, Van Scott MR, Fedan JS.

J Pharmacol Exp Ther. 2008 Jul;326(1):186-95. doi: 10.1124/jpet.107.135871. Epub 2008 Apr 15.

PMID:
18413857
22.

Altered ion transport and responsiveness to methacholine and hyperosmolarity in air interface-cultured guinea-pig tracheal epithelium.

Fedan JS, Wu DX, Van Scott MR.

J Pharmacol Toxicol Methods. 2007 Mar-Apr;55(2):135-43. Epub 2006 May 5.

PMID:
16793290
23.

Popcorn worker's lung: in vitro exposure to diacetyl, an ingredient in microwave popcorn butter flavoring, increases reactivity to methacholine.

Fedan JS, Dowdy JA, Fedan KB, Hubbs AF.

Toxicol Appl Pharmacol. 2006 Aug 15;215(1):17-22. Epub 2006 Mar 20.

PMID:
16545411
24.

Asthmalike biphasic airway responses in Brown Norway rats sensitized by dermal exposure to dry trimellitic anhydride powder.

Zhang XD, Fedan JS, Lewis DM, Siegel PD.

J Allergy Clin Immunol. 2004 Feb;113(2):320-6.

PMID:
14767449
25.

Hyperosmolar solution effects in guinea pig airways. IV. Lipopolysaccharide-induced alterations in airway reactivity and epithelial bioelectric responses to methacholine and hyperosmolarity.

Johnston RA, Van Scott MR, Kommineni C, Millecchia LL, Dortch-Carnes J, Fedan JS.

J Pharmacol Exp Ther. 2004 Jan;308(1):37-46. Epub 2003 Oct 17.

PMID:
14566002
26.

Hyperosmolar solution effects in guinea pig airways. III. Studies on the identity of epithelium-derived relaxing factor in isolated perfused trachea using pharmacological agents.

Fedan JS, Dowdy JA, Van Scott MR, Wu DX, Johnston RA.

J Pharmacol Exp Ther. 2004 Jan;308(1):30-6. Epub 2003 Oct 17.

PMID:
14566001
27.

Hyperosmolar solution effects in guinea pig airways. II. Epithelial bioelectric responses to relative changes in osmolarity.

Wu DX, Johnston RA, Rengasamy A, Van Scott MR, Fedan JS.

J Pharmacol Exp Ther. 2004 Jan;308(1):19-29. Epub 2003 Oct 17.

PMID:
14566000
28.

Hyperosmolar solution effects in guinea pig airways. I. Mechanical responses to relative changes in osmolarity.

Fedan JS, Dowdy JA, Johnston RA, Van Scott MR.

J Pharmacol Exp Ther. 2004 Jan;308(1):10-8. Epub 2003 Oct 16.

PMID:
14563782
29.

Necrosis of nasal and airway epithelium in rats inhaling vapors of artificial butter flavoring.

Hubbs AF, Battelli LA, Goldsmith WT, Porter DW, Frazer D, Friend S, Schwegler-Berry D, Mercer RR, Reynolds JS, Grote A, Castranova V, Kullman G, Fedan JS, Dowdy J, Jones WG.

Toxicol Appl Pharmacol. 2002 Dec 1;185(2):128-35.

PMID:
12490137
30.

Interleukin-1beta-induced airway hyperresponsiveness enhances substance P in intrinsic neurons of ferret airway.

Wu ZX, Satterfield BE, Fedan JS, Dey RD.

Am J Physiol Lung Cell Mol Physiol. 2002 Nov;283(5):L909-17.

31.

Pharmacological techniques for the in vitro study of airways.

Fedan JS, Van Scott MR, Johnston RA.

J Pharmacol Toxicol Methods. 2001 Mar-Apr;45(2):159-74. Review. No abstract available.

PMID:
11687382
32.

Hard metal-induced disease: effects of metal cations in vitro on guinea pig isolated airways.

Fedan JS, Cutler D.

Toxicol Appl Pharmacol. 2001 Aug 1;174(3):199-206.

PMID:
11485380
33.

Role of intrinsic airway neurons in ozone-induced airway hyperresponsiveness in ferret trachea.

Wu ZX, Maize DF Jr, Satterfield BE, Frazer DG, Fedan JS, Dey RD.

J Appl Physiol (1985). 2001 Jul;91(1):371-8.

34.

Effect of ozone treatment on airway reactivity and epithelium-derived relaxing factor in guinea pigs.

Fedan JS, Millecchia LL, Johnston RA, Rengasamy A, Hubbs A, Dey RD, Yuan LX, Watson D, Goldsmith WT, Reynolds JS, Orsini L, Dortch-Carnes J, Cutler D, Frazer DG.

J Pharmacol Exp Ther. 2000 Jun;293(3):724-34.

PMID:
10869370
35.

Ovalbumin aeroallergen exposure-response in Brown Norway rats.

Siegel PD, Al-Humadi NH, Millecchia LL, Robinson VA, Hubbs AF, Nelson ER, Fedan JS.

Inhal Toxicol. 2000 Mar;12(3):245-61.

PMID:
10715627
36.

Toluene diisocyanate enhances substance P in sensory neurons innervating the nasal mucosa.

Hunter DD, Satterfield BE, Huang J, Fedan JS, Dey RD.

Am J Respir Crit Care Med. 2000 Feb;161(2 Pt 1):543-9.

PMID:
10673198
37.

Nucleosides and nucleotides in the lung: role in asthma.

Fedan JS.

Am J Respir Cell Mol Biol. 1999 Jul;21(1):7-9. Review. No abstract available.

PMID:
10385586
38.

Effects of hard metal on nitric oxide pathways and airway reactivity to methacholine in rat lungs.

Rengasamy A, Kommineni C, Jones JA, Fedan JS.

Toxicol Appl Pharmacol. 1999 Jun 15;157(3):178-91.

PMID:
10373402
39.

Changes in smooth muscle tone during osmotic challenge in relation to epithelial bioelectric events in guinea pig isolated trachea.

Dortch-Carnes J, Van Scott MR, Fedan JS.

J Pharmacol Exp Ther. 1999 May;289(2):911-7.

PMID:
10215670
40.

Osmotic regulation of airway reactivity by epithelium.

Fedan JS, Yuan LX, Chang VC, Viola JO, Cutler D, Pettit LL.

J Pharmacol Exp Ther. 1999 May;289(2):901-10.

PMID:
10215669
41.

Characterization of neural control and contractile function in airway smooth muscle of the ferret.

Maize DF, Fedan JS, Dey RD.

Pulm Pharmacol Ther. 1998 Feb;11(1):57-64.

PMID:
9802964
42.
43.
45.

Pulmonary dendritic cell distribution and prevalence in guinea pig airways: effect of ovalbumin sensitization and challenge.

Lawrence TE, Millecchia LL, Frazer DG, Fedan JS.

J Pharmacol Exp Ther. 1997 Aug;282(2):995-1004.

PMID:
9262368
46.

Structure and function of P2 purinocepters.

Weisman GA, Turner JT, Fedan JS.

J Pharmacol Exp Ther. 1996 Apr;277(1):1-9. No abstract available.

PMID:
8613904
47.
48.

Nitric oxide synthase inhibitor and lipopolysaccharide effects on reactivity of guinea pig airways.

Fedan JS, Warner TE, Yuan LX, Robinson Va, Frazer DG.

J Pharmacol Exp Ther. 1995 Mar;272(3):1141-50.

PMID:
7534351
49.

Polarized effects of amiloride and 4,4'-diisothiocyano-stilbene-2,2'-disulfonic acid on ATP-induced contraction of trachea.

Fedan JS, Yuan LX, Belt JJ, Frazer DG.

Eur J Pharmacol. 1994 Apr 11;256(1):51-6.

PMID:
8026562
50.

Contraction of the guinea pig isolated, perfused trachea to purine and pyrimidine agonists.

Fedan JS, Stem JL, Day B.

J Pharmacol Exp Ther. 1994 Mar;268(3):1321-7.

PMID:
8138946

Supplemental Content

Loading ...
Support Center