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Items: 1 to 50 of 147

1.

Pressure drop mapping using 4D flow MRI in patients with bicuspid aortic valve disease: A novel marker of valvular obstruction.

Fatehi Hassanabad A, Burns F, Bristow MS, Lydell C, Howarth AG, Heydari B, Gao X, Fedak PWM, White JA, Garcia J.

Magn Reson Imaging. 2019 Nov 11;65:175-182. doi: 10.1016/j.mri.2019.11.011. [Epub ahead of print]

PMID:
31726212
2.

SKA-31, an activator of Ca2+-activated K+ channels, improves cardiovascular function in aging.

Mathew John C, Khaddaj Mallat R, Mishra RC, George G, Singh V, Turnbull JD, Umeshappa CS, Kendrick DJ, Kim T, Fauzi FM, Visser F, Fedak PW, Wulff H, Braun AP.

Pharmacol Res. 2019 Nov 7:104539. doi: 10.1016/j.phrs.2019.104539. [Epub ahead of print]

PMID:
31707036
3.

Commentary: Cause or consequence? The influence of mitral regurgitation on post-myocardial infarction structural remodeling is better defined using a new rodent model.

Deniset J, Fedak PWM.

J Thorac Cardiovasc Surg. 2019 Sep 23. pii: S0022-5223(19)31934-8. doi: 10.1016/j.jtcvs.2019.08.121. [Epub ahead of print] No abstract available.

PMID:
31610958
4.

Commentary: Blame the sculptors for the heart of stone-Uncovering cellular mechanisms of aortic valve calcification.

Svystonyuk DA, Fedak PWM.

J Thorac Cardiovasc Surg. 2019 Aug 22. pii: S0022-5223(19)31614-9. doi: 10.1016/j.jtcvs.2019.07.074. [Epub ahead of print] No abstract available.

PMID:
31519418
5.

Application of Bioengineered Materials in the Surgical Management of Heart Failure.

Pattar SS, Fatehi Hassanabad A, Fedak PWM.

Front Cardiovasc Med. 2019 Aug 20;6:123. doi: 10.3389/fcvm.2019.00123. eCollection 2019. Review.

6.

On the 'cusp' of clinical feasibility: aortic wall shear stress derived non-invasively with 4D flow MRI.

Bollache E, Fedak PWM, Markl M, Barker AJ.

J Thorac Dis. 2019 Jul;11(7):E96-E97. doi: 10.21037/jtd.2019.06.54. No abstract available.

7.

Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis.

Deniset JF, Belke D, Lee WY, Jorch SK, Deppermann C, Hassanabad AF, Turnbull JD, Teng G, Rozich I, Hudspeth K, Kanno Y, Brooks SR, Hadjantonakis AK, O'Shea JJ, Weber GF, Fedak PWM, Kubes P.

Immunity. 2019 Jul 16;51(1):131-140.e5. doi: 10.1016/j.immuni.2019.06.010.

PMID:
31315031
8.

Acellular Extracellular Matrix Bioscaffolds for Cardiac Repair and Regeneration.

Pattar SS, Fatehi Hassanabad A, Fedak PWM.

Front Cell Dev Biol. 2019 Apr 26;7:63. doi: 10.3389/fcell.2019.00063. eCollection 2019. Review.

9.

Minimally invasive cardiac surgery presents challenges for design of randomized clinical trials.

Ohno N, Hassanabad AF, Fedak PWM.

J Thorac Cardiovasc Surg. 2019 Apr;157(4):e133-e134. doi: 10.1016/j.jtcvs.2019.01.039. No abstract available.

PMID:
30901801
10.

Evolving Surgical Approaches to Bicuspid Aortic Valve Associated Aortopathy.

Fatehi Hassanabad A, Feindel CM, Verma S, Fedak PWM.

Front Cardiovasc Med. 2019 Mar 4;6:19. doi: 10.3389/fcvm.2019.00019. eCollection 2019.

11.

Minimally invasive cardiac surgery and the importance of qualitative patient-centered metrics to guide innovations.

Kent WDT, Fedak PWM.

J Thorac Cardiovasc Surg. 2019 Jun;157(6):e356-e357. doi: 10.1016/j.jtcvs.2019.02.018. Epub 2019 Mar 11. No abstract available.

PMID:
30871840
12.

Commentary: Using ex vivo modeling to validate technical innovations in cardiac surgery.

McClure RS, Fedak PWM.

J Thorac Cardiovasc Surg. 2019 Aug;158(2):404-405. doi: 10.1016/j.jtcvs.2019.02.010. Epub 2019 Feb 19. No abstract available.

PMID:
30857816
13.

Utilizing wall shear stress as a clinical biomarker for bicuspid valve-associated aortopathy.

Fatehi Hassanabad A, Garcia J, Verma S, White JA, Fedak PWM.

Curr Opin Cardiol. 2019 Mar;34(2):124-131. doi: 10.1097/HCO.0000000000000601.

PMID:
30633073
14.

Precision and targeted therapy in cardiac surgery.

Fatehi Hassanabad A, Fedak PWM.

J Thorac Dis. 2018 Nov;10(Suppl 33):S3986-S3988. doi: 10.21037/jtd.2018.09.90. No abstract available.

15.

Targeting selected extracellular matrix components to attenuate cardiac fibrosis.

Pattar SS, Fatehi Hassanabad A, Fedak PWM.

Ann Transl Med. 2018 Nov;6(Suppl 1):S49. doi: 10.21037/atm.2018.10.02. No abstract available.

16.

Validating innovations to improve recovery after heart surgery.

Fatehi Hassanabad A, Fedak PWM.

Ann Transl Med. 2018 Nov;6(Suppl 1):S13. doi: 10.21037/atm.2018.09.23. No abstract available.

17.

Coronary Bypass Surgery for Diabetes and Multivessel Disease: Forget the SYNTAX.

Fedak PWM, Bhatt DL, Verma S.

J Am Coll Cardiol. 2018 Dec 11;72(23 Pt A):2838-2840. doi: 10.1016/j.jacc.2018.10.011. No abstract available. Erratum in: J Am Coll Cardiol. 2019 Feb 5;73(4):535.

PMID:
30522647
18.

Induction of human aortic myofibroblast-mediated extracellular matrix dysregulation: A potential mechanism of fluoroquinolone-associated aortopathy.

Guzzardi DG, Teng G, Kang S, Geeraert PJ, Pattar SS, Svystonyuk DA, Belke DD, Fedak PWM.

J Thorac Cardiovasc Surg. 2019 Jan;157(1):109-119.e2. doi: 10.1016/j.jtcvs.2018.08.079. Epub 2018 Sep 21.

PMID:
30528439
19.

Commentary: Structural valve degeneration in the era of precision medicine.

Fedak PWM.

J Thorac Cardiovasc Surg. 2019 Apr;157(4):1391-1392. doi: 10.1016/j.jtcvs.2018.09.105. Epub 2018 Oct 10. No abstract available.

PMID:
30389129
20.

Make sternotomy great again.

Fedak PWM.

J Thorac Cardiovasc Surg. 2018 Dec;156(6):2133-2134. doi: 10.1016/j.jtcvs.2018.06.076. Epub 2018 Jul 19. No abstract available.

PMID:
30107920
21.

Modify, simplify, apply: Do we need preclinical models for surgical innovation?

Hassanabad AF, Fedak PWM.

J Thorac Cardiovasc Surg. 2018 Nov;156(5):1869-1870. doi: 10.1016/j.jtcvs.2018.07.024. Epub 2018 Jul 20. No abstract available.

PMID:
30098807
22.

Bioactive Extracellular Matrix Scaffold Promotes Adaptive Cardiac Remodeling and Repair.

Mewhort HEM, Svystonyuk DA, Turnbull JD, Teng G, Belke DD, Guzzardi DG, Park DS, Kang S, Hollenberg MD, Fedak PWM.

JACC Basic Transl Sci. 2017 Aug 18;2(4):450-464. doi: 10.1016/j.jacbts.2017.05.005. eCollection 2017 Aug.

23.

Empagliflozin Prevents Worsening of Cardiac Function in an Experimental Model of Pressure Overload-Induced Heart Failure.

Byrne NJ, Parajuli N, Levasseur JL, Boisvenue J, Beker DL, Masson G, Fedak PWM, Verma S, Dyck JRB.

JACC Basic Transl Sci. 2017 Aug 4;2(4):347-354. doi: 10.1016/j.jacbts.2017.07.003. eCollection 2017 Aug. Review.

24.

Aortic valve-mediated wall shear stress is heterogeneous and predicts regional aortic elastic fiber thinning in bicuspid aortic valve-associated aortopathy.

Bollache E, Guzzardi DG, Sattari S, Olsen KE, Di Martino ES, Malaisrie SC, van Ooij P, Collins J, Carr J, McCarthy PM, Markl M, Barker AJ, Fedak PWM.

J Thorac Cardiovasc Surg. 2018 Dec;156(6):2112-2120.e2. doi: 10.1016/j.jtcvs.2018.05.095. Epub 2018 Jun 12.

PMID:
30060930
25.

The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Full online-only version.

Borger MA, Fedak PWM, Stephens EH, Gleason TG, Girdauskas E, Ikonomidis JS, Khoynezhad A, Siu SC, Verma S, Hope MD, Cameron DE, Hammer DF, Coselli JS, Moon MR, Sundt TM, Barker AJ, Markl M, Della Corte A, Michelena HI, Elefteriades JA.

J Thorac Cardiovasc Surg. 2018 Aug;156(2):e41-e74. doi: 10.1016/j.jtcvs.2018.02.115.

26.

The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Executive summary.

Borger MA, Fedak PWM, Stephens EH, Gleason TG, Girdauskas E, Ikonomidis JS, Khoynezhad A, Siu SC, Verma S, Hope MD, Cameron DE, Hammer DF, Coselli JS, Moon MR, Sundt TM, Barker AJ, Markl M, Della Corte A, Michelena HI, Elefteriades JA.

J Thorac Cardiovasc Surg. 2018 Aug;156(2):473-480. doi: 10.1016/j.jtcvs.2017.10.161.

27.

Cell-Specific Functions of ADAM17 Regulate the Progression of Thoracic Aortic Aneurysm.

Shen M, Hu M, Fedak PWM, Oudit GY, Kassiri Z.

Circ Res. 2018 Jul 20;123(3):372-388. doi: 10.1161/CIRCRESAHA.118.313181. Epub 2018 Jun 21.

PMID:
29930147
28.

Hyperglycaemic impairment of PAR2-mediated vasodilation: Prevention by inhibition of aortic endothelial sodium-glucose-co-Transporter-2 and minimizing oxidative stress.

El-Daly M, Pulakazhi Venu VK, Saifeddine M, Mihara K, Kang S, Fedak PWM, Alston LA, Hirota SA, Ding H, Triggle CR, Hollenberg MD.

Vascul Pharmacol. 2018 Oct;109:56-71. doi: 10.1016/j.vph.2018.06.006. Epub 2018 Jun 13.

PMID:
29908295
29.

Human pericardial proteoglycan 4 (lubricin): Implications for postcardiotomy intrathoracic adhesion formation.

Park DSJ, Regmi SC, Svystonyuk DA, Teng G, Belke D, Turnbull J, Guzzardi DG, Kang S, Cowman MK, Schmidt TA, Fedak PWM.

J Thorac Cardiovasc Surg. 2018 Oct;156(4):1598-1608.e1. doi: 10.1016/j.jtcvs.2018.03.170. Epub 2018 Apr 26.

PMID:
29859675
30.

Using Acellular Bioactive Extracellular Matrix Scaffolds to Enhance Endogenous Cardiac Repair.

Svystonyuk DA, Mewhort HEM, Fedak PWM.

Front Cardiovasc Med. 2018 Apr 11;5:35. doi: 10.3389/fcvm.2018.00035. eCollection 2018.

31.

Assessing wall stresses in bicuspid aortic valve-associated aortopathy: Forecasting the perfect storm?

Barker AJ, Markl M, Fedak PWM.

J Thorac Cardiovasc Surg. 2018 Aug;156(2):471-472. doi: 10.1016/j.jtcvs.2018.03.092. Epub 2018 Mar 31. No abstract available.

PMID:
29666014
32.

Aortic Valve Replacement in an Era of Rapid Innovation: Better the Devil You Know.

Fedak PWM, Bhatt DL, Verma S.

J Am Coll Cardiol. 2018 Apr 3;71(13):1413-1416. doi: 10.1016/j.jacc.2018.02.007. No abstract available.

33.

Aortic diameter: The beginning of the end of an era.

Gregory AJ, Di Martino E, Fedak PWM.

J Thorac Cardiovasc Surg. 2018 Aug;156(2):513-514. doi: 10.1016/j.jtcvs.2018.01.079. Epub 2018 Feb 13. No abstract available.

PMID:
29510930
34.

Bridging to heart transplant with extracorporeal membrane oxygenation: Good or VAD?

Parhar KK, Fedak PWM.

J Thorac Cardiovasc Surg. 2018 Apr;155(4):1619-1620. doi: 10.1016/j.jtcvs.2017.12.001. Epub 2017 Dec 9. No abstract available.

PMID:
29310932
35.

Seeing a tree through the forest: Precision medicine tools can enhance donor allocation in heart transplantation.

Vasanthan V, Fedak PWM.

J Thorac Cardiovasc Surg. 2018 Apr;155(4):1591-1592. doi: 10.1016/j.jtcvs.2017.12.008. Epub 2017 Dec 9. No abstract available.

PMID:
29310930
36.

Perioperative evaluation of regional aortic wall shear stress patterns in patients undergoing aortic valve and/or proximal thoracic aortic replacement.

Bollache E, Fedak PWM, van Ooij P, Rahman O, Malaisrie SC, McCarthy PM, Carr JC, Powell A, Collins JD, Markl M, Barker AJ.

J Thorac Cardiovasc Surg. 2018 Jun;155(6):2277-2286.e2. doi: 10.1016/j.jtcvs.2017.11.007. Epub 2017 Nov 16.

37.

Mind the Gap: Current Challenges and Future State of Heart Failure Care.

McDonald MA, Ashley EA, Fedak PWM, Hawkins N, Januzzi JL, McMurray JJV, Parikh VN, Rao V, Svystonyuk D, Teerlink JR, Virani S.

Can J Cardiol. 2017 Nov;33(11):1434-1449. doi: 10.1016/j.cjca.2017.08.023. Epub 2017 Sep 5. Review.

PMID:
29111107
38.

Bicuspid aortic valve-associated aortopathy: update on biomarkers.

Maredia AK, Greenway SC, Verma S, Fedak PWM.

Curr Opin Cardiol. 2018 Mar;33(2):134-139. doi: 10.1097/HCO.0000000000000481. Review.

PMID:
29095713
39.

Aortic Valve Stenosis Alters Expression of Regional Aortic Wall Shear Stress: New Insights From a 4-Dimensional Flow Magnetic Resonance Imaging Study of 571 Subjects.

van Ooij P, Markl M, Collins JD, Carr JC, Rigsby C, Bonow RO, Malaisrie SC, McCarthy PM, Fedak PWM, Barker AJ.

J Am Heart Assoc. 2017 Sep 13;6(9). pii: e005959. doi: 10.1161/JAHA.117.005959.

40.

Evolution of Precision Medicine and Surgical Strategies for Bicuspid Aortic Valve-Associated Aortopathy.

Fatehi Hassanabad A, Barker AJ, Guzzardi D, Markl M, Malaisrie C, McCarthy PM, Fedak PWM.

Front Physiol. 2017 Jul 10;8:475. doi: 10.3389/fphys.2017.00475. eCollection 2017.

41.

The Cost of Frailty in Cardiac Surgery.

Yanagawa B, Latter DA, Fedak PWM, Cutrara C, Verma S.

Can J Cardiol. 2017 Aug;33(8):959-960. doi: 10.1016/j.cjca.2017.05.015. Epub 2017 May 25. No abstract available.

PMID:
28666616
42.

Adhesive-Enhanced Sternal Closure: Feasibility and Safety of Late Sternal Reentry.

Spooner AJ, Mewhort HEM, DiFrancesco LM, Fedak PWM.

Case Rep Surg. 2017;2017:8605313. doi: 10.1155/2017/8605313. Epub 2017 May 29.

43.

Heparin Augmentation Enhances Bioactive Properties of Acellular Extracellular Matrix Scaffold.

Park DSJ, Mewhort HEM, Teng G, Belke D, Turnbull J, Svystonyuk D, Guzzardi D, Kang S, Fedak PWM.

Tissue Eng Part A. 2018 Jan;24(1-2):128-134. doi: 10.1089/ten.TEA.2017.0004. Epub 2017 Aug 21.

PMID:
28457186
44.

Bicuspid aortic valve and the specialty clinic: are your patients at risk?

Fedak PWM.

Cardiol Young. 2017 Apr;27(3):411-412. doi: 10.1017/S1047951117000282. Epub 2017 Mar 6. No abstract available.

PMID:
28260551
45.

Bicuspid aortic valve aortopathy: mechanistic and clinical insights from recent studies.

Guzzardi DG, Verma S, Fedak PW.

Curr Opin Cardiol. 2017 Mar;32(2):111-116. doi: 10.1097/HCO.0000000000000359. Review.

PMID:
28182589
46.

Safety and efficacy of prophylactic negative pressure wound therapy following open saphenous vein harvest in cardiac surgery: a feasibility study.

Lee AJ, Sheppard CE, Kent WD, Mewhort H, Sikdar KC, Fedak PW.

Interact Cardiovasc Thorac Surg. 2017 Mar 1;24(3):324-328. doi: 10.1093/icvts/ivw400.

PMID:
28025309
47.

Is Concomitant Aortopathy Unique With Bicuspid Aortic Valve Stenosis?

Fedak PWM, Barker AJ.

J Am Coll Cardiol. 2016 Apr 19;67(15):1797-1799. doi: 10.1016/j.jacc.2016.02.038. No abstract available.

48.

Reply: Importance of Stress Mapping of Aortic Wall in Aortic Valve Disease.

Barker AJ, Guzzardi D, Markl M, Fedak PW.

J Am Coll Cardiol. 2016 Apr 12;67(14):1756-7. doi: 10.1016/j.jacc.2016.01.047. No abstract available.

49.

Real estate of the bicuspid aorta: Location, location, location!

Fedak PW, Guzzardi DG.

J Thorac Cardiovasc Surg. 2016 Jun;151(6):1728-9. doi: 10.1016/j.jtcvs.2016.02.048. Epub 2016 Feb 27. No abstract available.

50.

Epicardial infarct repair with bioinductive extracellular matrix promotes vasculogenesis and myocardial recovery.

Mewhort HE, Turnbull JD, Satriano A, Chow K, Flewitt JA, Andrei AC, Guzzardi DG, Svystonyuk DA, White JA, Fedak PW.

J Heart Lung Transplant. 2016 May;35(5):661-70. doi: 10.1016/j.healun.2016.01.012. Epub 2016 Jan 15.

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