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Items: 1 to 50 of 393

1.

Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer.

Watt MJ, Clark AK, Selth LA, Haynes VR, Lister N, Rebello R, Porter LH, Niranjan B, Whitby ST, Lo J, Huang C, Schittenhelm RB, Anderson KE, Furic L, Wijayaratne PR, Matzaris M, Montgomery MK, Papargiris M, Norden S, Febbraio M, Risbridger GP, Frydenberg M, Nomura DK, Taylor RA.

Sci Transl Med. 2019 Feb 6;11(478). pii: eaau5758. doi: 10.1126/scitranslmed.aau5758.

PMID:
30728288
2.

CD36 mediates albumin transcytosis by dermal but not lung microvascular endothelial cells - role in fatty acid delivery.

Raheel H, Ghaffari S, Khosraviani N, Mintsopoulos V, Auyeung D, Wang C, Kim YH, Mullen B, Sung HK, Ho M, Fairn G, Neculai D, Febbraio M, Heit B, Lee WL.

Am J Physiol Lung Cell Mol Physiol. 2019 Jan 31. doi: 10.1152/ajplung.00127.2018. [Epub ahead of print]

PMID:
30702342
3.

Author Correction: Relieving ER stress to target NASH-driven hepatocellular carcinoma.

Reibe S, Febbraio MA.

Nat Rev Endocrinol. 2019 Feb;15(2):126. doi: 10.1038/s41574-019-0154-1.

PMID:
30610220
4.

CD36 Enhances Vascular Smooth Muscle Cell Proliferation and Development of Neointimal Hyperplasia.

Yue H, Febbraio M, Klenotic PA, Kennedy DJ, Wu Y, Chen S, Gohara AF, Li O, Belcher A, Kuang B, McIntyre TM, Silverstein RL, Li W.

Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):263-275. doi: 10.1161/ATVBAHA.118.312186.

PMID:
30567481
5.

Relieving ER stress to target NASH-driven hepatocellular carcinoma.

Reibe S, Febbraio MA.

Nat Rev Endocrinol. 2019 Feb;15(2):73-74. doi: 10.1038/s41574-018-0145-7. No abstract available. Erratum in: Nat Rev Endocrinol. 2019 Jan 8;:.

PMID:
30552380
6.

Preclinical Models for Studying NASH-Driven HCC: How Useful Are They?

Febbraio MA, Reibe S, Shalapour S, Ooi GJ, Watt MJ, Karin M.

Cell Metab. 2019 Jan 8;29(1):18-26. doi: 10.1016/j.cmet.2018.10.012. Epub 2018 Nov 15. Review.

PMID:
30449681
7.

Implications of X-ray beam profiles on qualitative and quantitative synchrotron micro-focus X-ray fluorescence microscopy.

Morrell AP, Mosselmans JFW, Geraki K, Ignatyev K, Castillo-Michel H, Monksfield P, Warfield AT, Febbraio M, Roberts HM, Addison O, Martin RA.

J Synchrotron Radiat. 2018 Nov 1;25(Pt 6):1719-1726. doi: 10.1107/S160057751801247X. Epub 2018 Sep 28.

PMID:
30407182
8.

Redefining Tissue Crosstalk via Shotgun Proteomic Analyses of Plasma Extracellular Vesicles.

Whitham M, Febbraio MA.

Proteomics. 2019 Jan;19(1-2):e1800154. doi: 10.1002/pmic.201800154. Epub 2018 Nov 29.

PMID:
30350444
9.

Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance.

Brandon AE, Liao BM, Diakanastasis B, Parker BL, Raddatz K, McManus SA, O'Reilly L, Kimber E, van der Kraan AG, Hancock D, Henstridge DC, Meikle PJ, Cooney GJ, James DE, Reibe S, Febbraio MA, Biden TJ, Schmitz-Peiffer C.

Cell Metab. 2019 Jan 8;29(1):183-191.e7. doi: 10.1016/j.cmet.2018.09.013. Epub 2018 Oct 11.

PMID:
30318338
10.

Exercise as medicine for survivors of paediatric cancer.

Hjorth M, Febbraio MA.

Nat Rev Endocrinol. 2018 Sep;14(9):506-508. doi: 10.1038/s41574-018-0065-6. No abstract available.

PMID:
30022101
11.

Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis.

Dragoljevic D, Kraakman MJ, Nagareddy PR, Ngo D, Shihata W, Kammoun HL, Whillas A, Lee MKS, Al-Sharea A, Pernes G, Flynn MC, Lancaster GI, Febbraio MA, Chin-Dusting J, Hanaoka BY, Wicks IP, Murphy AJ.

Eur Heart J. 2018 Jun 14;39(23):2158-2167. doi: 10.1093/eurheartj/ehy119.

PMID:
29905812
12.

Dyslipidemia-associated atherogenic oxidized lipids induce platelet hyperactivity through phospholipase Cγ2-dependent reactive oxygen species generation.

Berger M, Wraith K, Woodward C, Aburima A, Raslan Z, Hindle MS, Moellmann J, Febbraio M, Naseem KM.

Platelets. 2018 May 7:1-6. doi: 10.1080/09537104.2018.1466386. [Epub ahead of print]

PMID:
29733744
13.

Female sex hormones are necessary for the metabolic effects mediated by loss of Interleukin 18 signaling.

Lindegaard B, Abildgaard J, Heywood SE, Pedersen BK, Febbraio MA.

Mol Metab. 2018 Jun;12:89-97. doi: 10.1016/j.molmet.2018.04.005. Epub 2018 Apr 12.

14.

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism.

Lancaster GI, Langley KG, Berglund NA, Kammoun HL, Reibe S, Estevez E, Weir J, Mellett NA, Pernes G, Conway JRW, Lee MKS, Timpson P, Murphy AJ, Masters SL, Gerondakis S, Bartonicek N, Kaczorowski DC, Dinger ME, Meikle PJ, Bond PJ, Febbraio MA.

Cell Metab. 2018 May 1;27(5):1096-1110.e5. doi: 10.1016/j.cmet.2018.03.014. Epub 2018 Apr 19.

PMID:
29681442
15.

APP deficiency results in resistance to obesity but impairs glucose tolerance upon high fat feeding.

Czeczor JK, Genders AJ, Aston-Mourney K, Connor T, Hall LG, Hasebe K, Ellis M, De Jong KA, Henstridge DC, Meikle PJ, Febbraio MA, Walder K, McGee SL.

J Endocrinol. 2018 Jun;237(3):311-322. doi: 10.1530/JOE-18-0051. Epub 2018 Apr 19.

PMID:
29674342
16.

Skeletal muscle-specific overexpression of heat shock protein 72 improves skeletal muscle insulin-stimulated glucose uptake but does not alter whole body metabolism.

Marshall JPS, Estevez E, Kammoun HL, King EJ, Bruce CR, Drew BG, Qian H, Iliades P, Gregorevic P, Febbraio MA, Henstridge DC.

Diabetes Obes Metab. 2018 Aug;20(8):1928-1936. doi: 10.1111/dom.13319. Epub 2018 May 3.

PMID:
29652108
17.

GeneXX: an online tool for the exploration of transcript changes in skeletal muscle associated with exercise.

Reibe S, Hjorth M, Febbraio MA, Whitham M.

Physiol Genomics. 2018 May 1;50(5):376-384. doi: 10.1152/physiolgenomics.00127.2017. Epub 2018 Mar 16.

PMID:
29547064
18.

Evidence against a role for NLRP3-driven islet inflammation in db/db mice.

Kammoun HL, Allen TL, Henstridge DC, Barre S, Coll RC, Lancaster GI, Cron L, Reibe S, Chan JY, Bensellam M, Laybutt DR, Butler MS, Robertson AAB, O'Neill LA, Cooper MA, Febbraio MA.

Mol Metab. 2018 Apr;10:66-73. doi: 10.1016/j.molmet.2018.02.001. Epub 2018 Feb 7.

19.

Activation of mitochondrial fusion provides a new treatment for mitochondria-related diseases.

Szabo A, Sumegi K, Fekete K, Hocsak E, Debreceni B, Setalo G Jr, Kovacs K, Deres L, Kengyel A, Kovacs D, Mandl J, Nyitrai M, Febbraio MA, Gallyas F Jr, Sumegi B.

Biochem Pharmacol. 2018 Apr;150:86-96. doi: 10.1016/j.bcp.2018.01.038. Epub 2018 Feb 3.

20.

Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise.

Whitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA.

Cell Metab. 2018 Jan 9;27(1):237-251.e4. doi: 10.1016/j.cmet.2017.12.001.

21.

Editorial: What is the value of basic researchers in dentistry?

Febbraio M, Flood P, Levin L.

Quintessence Int. 2018;49(2):87-88. doi: 10.3290/j.qi.a39645. No abstract available.

PMID:
29292404
22.

Transcription Factor IRF4 Promotes CD8+ T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection.

Man K, Gabriel SS, Liao Y, Gloury R, Preston S, Henstridge DC, Pellegrini M, Zehn D, Berberich-Siebelt F, Febbraio MA, Shi W, Kallies A.

Immunity. 2017 Dec 19;47(6):1129-1141.e5. doi: 10.1016/j.immuni.2017.11.021. Epub 2017 Dec 12.

23.

High-density lipoprotein delivered after myocardial infarction increases cardiac glucose uptake and function in mice.

Heywood SE, Richart AL, Henstridge DC, Alt K, Kiriazis H, Zammit C, Carey AL, Kammoun HL, Delbridge LM, Reddy M, Chen YC, Du XJ, Hagemeyer CE, Febbraio MA, Siebel AL, Kingwell BA.

Sci Transl Med. 2017 Oct 11;9(411). pii: eaam6084. doi: 10.1126/scitranslmed.aam6084.

PMID:
29021167
24.

Adiponectin has a pivotal role in the cardioprotective effect of CP-3(iv), a selective CD36 azapeptide ligand, after transient coronary artery occlusion in mice.

Huynh DN, Bessi VL, Ménard L, Piquereau J, Proulx C, Febbraio M, Lubell WD, Carpentier AC, Burelle Y, Ong H, Marleau S.

FASEB J. 2018 Feb;32(2):807-818. doi: 10.1096/fj.201700505R. Epub 2018 Jan 4.

PMID:
29018142
25.

Increased liver AGEs induce hepatic injury mediated through an OST48 pathway.

Zhuang A, Yap FY, Bruce C, Leung C, Plan MR, Sullivan MA, Herath C, McCarthy D, Sourris KC, Kantharidis P, Coughlan MT, Febbraio MA, Hodson MP, Watt MJ, Angus P, Schulz BL, Forbes JM.

Sci Rep. 2017 Sep 25;7(1):12292. doi: 10.1038/s41598-017-12548-4.

26.

Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice.

Kammoun HL, Allen TL, Henstridge DC, Kraakman MJ, Peijs L, Rose-John S, Febbraio MA.

PLoS One. 2017 Jun 20;12(6):e0179099. doi: 10.1371/journal.pone.0179099. eCollection 2017.

27.

Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes.

Kraakman MJ, Lee MK, Al-Sharea A, Dragoljevic D, Barrett TJ, Montenont E, Basu D, Heywood S, Kammoun HL, Flynn M, Whillas A, Hanssen NM, Febbraio MA, Westein E, Fisher EA, Chin-Dusting J, Cooper ME, Berger JS, Goldberg IJ, Nagareddy PR, Murphy AJ.

J Clin Invest. 2017 Jun 1;127(6):2133-2147. doi: 10.1172/JCI92450. Epub 2017 May 15.

28.

The Upregulation of Integrin αDβ2 (CD11d/CD18) on Inflammatory Macrophages Promotes Macrophage Retention in Vascular Lesions and Development of Atherosclerosis.

Aziz MH, Cui K, Das M, Brown KE, Ardell CL, Febbraio M, Pluskota E, Han J, Wu H, Ballantyne CM, Smith JD, Cathcart MK, Yakubenko VP.

J Immunol. 2017 Jun 15;198(12):4855-4867. doi: 10.4049/jimmunol.1602175. Epub 2017 May 12.

29.

A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease.

PrabhuDas MR, Baldwin CL, Bollyky PL, Bowdish DME, Drickamer K, Febbraio M, Herz J, Kobzik L, Krieger M, Loike J, McVicker B, Means TK, Moestrup SK, Post SR, Sawamura T, Silverstein S, Speth RC, Telfer JC, Thiele GM, Wang XY, Wright SD, El Khoury J.

J Immunol. 2017 May 15;198(10):3775-3789. doi: 10.4049/jimmunol.1700373.

30.

Apical periodontitis and atherosclerosis: 
Is there a link? Review of the literature and potential mechanism of linkage.

Berlin-Broner Y, Febbraio M, Levin L.

Quintessence Int. 2017;48(7):527-534. doi: 10.3290/j.qi.a38162. Review.

PMID:
28462408
31.

CD36 receptor regulates malaria-induced immune responses primarily at early blood stage infection contributing to parasitemia control and resistance to mortality.

Thylur RP, Wu X, Gowda NM, Punnath K, Neelgund SE, Febbraio M, Gowda DC.

J Biol Chem. 2017 Jun 2;292(22):9394-9408. doi: 10.1074/jbc.M117.781294. Epub 2017 Apr 17.

32.

Adiponectin serenades ceramidase to improve metabolism.

Reibe-Pal S, Febbraio MA.

Mol Metab. 2017 Feb 1;6(3):233-235. doi: 10.1016/j.molmet.2017.01.011. eCollection 2017 Mar. No abstract available.

33.

IL-1β delivers a sweet deal.

Hjorth M, Febbraio MA.

Nat Immunol. 2017 Feb 15;18(3):247-248. doi: 10.1038/ni.3681. No abstract available.

PMID:
28198823
34.

Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice.

Gaur V, Connor T, Venardos K, Henstridge DC, Martin SD, Swinton C, Morrison S, Aston-Mourney K, Gehrig SM, van Ewijk R, Lynch GS, Febbraio MA, Steinberg GR, Hargreaves M, Walder KR, McGee SL.

Diabetes Obes Metab. 2017 Jul;19(7):936-943. doi: 10.1111/dom.12896. Epub 2017 Mar 3.

PMID:
28155245
35.

Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects.

Keshvari S, Henstridge DC, Ng C, Febbraio MA, Whitehead JP.

Sci Rep. 2017 Feb 1;7:41792. doi: 10.1038/srep41792.

36.

Aggressive periodontitis: The unsolved mystery.

Clark D, Febbraio M, Levin L.

Quintessence Int. 2017;48(2):103-111. doi: 10.3290/j.qi.a37387. Review.

PMID:
28133644
37.

Cardiomyocyte-specific ablation of CD36 accelerates the progression from compensated cardiac hypertrophy to heart failure.

Sung MM, Byrne NJ, Kim TT, Levasseur J, Masson G, Boisvenue JJ, Febbraio M, Dyck JR.

Am J Physiol Heart Circ Physiol. 2017 Mar 1;312(3):H552-H560. doi: 10.1152/ajpheart.00626.2016. Epub 2017 Jan 6.

38.

Exercise metabolism in 2016: Health benefits of exercise - more than meets the eye!

Febbraio MA.

Nat Rev Endocrinol. 2017 Feb;13(2):72-74. doi: 10.1038/nrendo.2016.218. Epub 2017 Jan 4. Review. No abstract available.

PMID:
28051119
39.

Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO).

Wolf D, Bukosza N, Engel D, Poggi M, Jehle F, Anto Michel N, Chen YC, Colberg C, Hoppe N, Dufner B, Boon L, Blankenbach H, Hilgendorf I, von Zur Muhlen C, Reinöhl J, Sommer B, Marchini T, Febbraio MA, Weber C, Bode C, Peter K, Lutgens E, Zirlik A.

Thromb Haemost. 2017 Jan 26;117(2):325-338. doi: 10.1160/TH16-07-0553. Epub 2016 Nov 17.

PMID:
27853810
40.

Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle.

Lee-Young RS, Hoffman NJ, Murphy KT, Henstridge DC, Samocha-Bonet D, Siebel AL, Iliades P, Zivanovic B, Hong YH, Colgan TD, Kraakman MJ, Bruce CR, Gregorevic P, McConell GK, Lynch GS, Drummond GR, Kingwell BA, Greenfield JR, Febbraio MA.

Mol Metab. 2016 Sep 9;5(11):1083-1091. doi: 10.1016/j.molmet.2016.09.002. eCollection 2016 Nov.

41.

Association between apical periodontitis and cardiovascular diseases: a systematic review of the literature.

Berlin-Broner Y, Febbraio M, Levin L.

Int Endod J. 2017 Sep;50(9):847-859. doi: 10.1111/iej.12710. Epub 2016 Nov 19. Review.

PMID:
27770442
42.

BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle.

Kennedy TL, Swiderski K, Murphy KT, Gehrig SM, Curl CL, Chandramouli C, Febbraio MA, Delbridge LM, Koopman R, Lynch GS.

Am J Pathol. 2016 Dec;186(12):3246-3260. doi: 10.1016/j.ajpath.2016.08.008. Epub 2016 Oct 14.

PMID:
27750047
43.

Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity.

Cropley JE, Eaton SA, Aiken A, Young PE, Giannoulatou E, Ho JWK, Buckland ME, Keam SP, Hutvagner G, Humphreys DT, Langley KG, Henstridge DC, Martin DIK, Febbraio MA, Suter CM.

Mol Metab. 2016 Jun 23;5(8):699-708. doi: 10.1016/j.molmet.2016.06.008. eCollection 2016 Aug.

44.

Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation.

Gaur V, Connor T, Sanigorski A, Martin SD, Bruce CR, Henstridge DC, Bond ST, McEwen KA, Kerr-Bayles L, Ashton TD, Fleming C, Wu M, Pike Winer LS, Chen D, Hudson GM, Schwabe JWR, Baar K, Febbraio MA, Gregorevic P, Pfeffer FM, Walder KR, Hargreaves M, McGee SL.

Cell Rep. 2016 Sep 13;16(11):2802-2810. doi: 10.1016/j.celrep.2016.08.005.

45.

The ever-expanding myokinome: discovery challenges and therapeutic implications.

Whitham M, Febbraio MA.

Nat Rev Drug Discov. 2016 Oct;15(10):719-29. doi: 10.1038/nrd.2016.153. Epub 2016 Sep 12. Review.

PMID:
27616294
46.

High Fat Diet Inhibits Dendritic Cell and T Cell Response to Allergens but Does Not Impair Inhalational Respiratory Tolerance.

Pizzolla A, Oh DY, Luong S, Prickett SR, Henstridge DC, Febbraio MA, O'Hehir RE, Rolland JM, Hardy CL.

PLoS One. 2016 Aug 2;11(8):e0160407. doi: 10.1371/journal.pone.0160407. eCollection 2016.

47.

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.

de Valle E, Grigoriadis G, O'Reilly LA, Willis SN, Maxwell MJ, Corcoran LM, Tsantikos E, Cornish JK, Fairfax KA, Vasanthakumar A, Febbraio MA, Hibbs ML, Pellegrini M, Banerjee A, Hodgkin PD, Kallies A, Mackay F, Strasser A, Gerondakis S, Gugasyan R.

J Exp Med. 2016 Apr 4;213(4):621-41. doi: 10.1084/jem.20151182. Epub 2016 Mar 28.

48.

PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications.

Lancaster GI, Kammoun HL, Kraakman MJ, Kowalski GM, Bruce CR, Febbraio MA.

Nat Commun. 2016 Feb 3;7:10626. doi: 10.1038/ncomms10626.

49.

The role of gp130 receptor cytokines in the regulation of metabolic homeostasis.

Cron L, Allen T, Febbraio MA.

J Exp Biol. 2016 Jan;219(Pt 2):259-65. doi: 10.1242/jeb.129213. Review.

50.

Heat shock proteins and exercise adaptations. Our knowledge thus far and the road still ahead.

Henstridge DC, Febbraio MA, Hargreaves M.

J Appl Physiol (1985). 2016 Mar 15;120(6):683-91. doi: 10.1152/japplphysiol.00811.2015. Epub 2015 Dec 17. Review.

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