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Items: 18

1.

Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer.

Korpal M, Puyang X, Jeremy Wu Z, Seiler R, Furman C, Oo HZ, Seiler M, Irwin S, Subramanian V, Julie Joshi J, Wang CK, Rimkunas V, Tortora D, Yang H, Kumar N, Kuznetsov G, Matijevic M, Chow J, Kumar P, Zou J, Feala J, Corson L, Henry R, Selvaraj A, Davis A, Bloudoff K, Douglas J, Kiss B, Roberts M, Fazli L, Black PC, Fekkes P, Smith PG, Warmuth M, Yu L, Hao MH, Larsen N, Daugaard M, Zhu P.

Nat Commun. 2017 Jul 24;8(1):103. doi: 10.1038/s41467-017-00147-w.

2.

Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.

Teng T, Tsai JH, Puyang X, Seiler M, Peng S, Prajapati S, Aird D, Buonamici S, Caleb B, Chan B, Corson L, Feala J, Fekkes P, Gerard B, Karr C, Korpal M, Liu X, T Lowe J, Mizui Y, Palacino J, Park E, Smith PG, Subramanian V, Wu ZJ, Zou J, Yu L, Chicas A, Warmuth M, Larsen N, Zhu P.

Nat Commun. 2017 May 25;8:15522. doi: 10.1038/ncomms15522.

3.

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms.

Korpal M, Feala J, Puyang X, Zou J, Ramos AH, Wu J, Baumeister T, Yu L, Warmuth M, Zhu P.

J Vis Exp. 2015 Dec 9;(106):e52879. doi: 10.3791/52879.

4.

Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3' Splice Site Selection through Use of a Different Branch Point.

Darman RB, Seiler M, Agrawal AA, Lim KH, Peng S, Aird D, Bailey SL, Bhavsar EB, Chan B, Colla S, Corson L, Feala J, Fekkes P, Ichikawa K, Keaney GF, Lee L, Kumar P, Kunii K, MacKenzie C, Matijevic M, Mizui Y, Myint K, Park ES, Puyang X, Selvaraj A, Thomas MP, Tsai J, Wang JY, Warmuth M, Yang H, Zhu P, Garcia-Manero G, Furman RR, Yu L, Smith PG, Buonamici S.

Cell Rep. 2015 Nov 3;13(5):1033-45. doi: 10.1016/j.celrep.2015.09.053. Epub 2015 Oct 22.

5.

A systems biology strategy to identify molecular mechanisms of action and protein indicators of traumatic brain injury.

Yu C, Boutté A, Yu X, Dutta B, Feala JD, Schmid K, Dave J, Tawa GJ, Wallqvist A, Reifman J.

J Neurosci Res. 2015 Feb;93(2):199-214. doi: 10.1002/jnr.23503. Epub 2014 Nov 14.

6.

Systems biology approaches for discovering biomarkers for traumatic brain injury.

Feala JD, Abdulhameed MD, Yu C, Dutta B, Yu X, Schmid K, Dave J, Tortella F, Reifman J.

J Neurotrauma. 2013 Jul 1;30(13):1101-16. doi: 10.1089/neu.2012.2631. Review.

7.

Statistical properties and robustness of biological controller-target networks.

Feala JD, Cortes J, Duxbury PM, McCulloch AD, Piermarocchi C, Paternostro G.

PLoS One. 2012;7(1):e29374. doi: 10.1371/journal.pone.0029374. Epub 2012 Jan 3.

8.

Systems approaches and algorithms for discovery of combinatorial therapies.

Feala JD, Cortes J, Duxbury PM, Piermarocchi C, McCulloch AD, Paternostro G.

Wiley Interdiscip Rev Syst Biol Med. 2010 Mar-Apr;2(2):181-193. doi: 10.1002/wsbm.51. Review.

PMID:
20836021
9.

Metabolism as means for hypoxia adaptation: metabolic profiling and flux balance analysis.

Feala JD, Coquin L, Zhou D, Haddad GG, Paternostro G, McCulloch AD.

BMC Syst Biol. 2009 Sep 9;3:91. doi: 10.1186/1752-0509-3-91.

10.

Search algorithms as a framework for the optimization of drug combinations.

Calzolari D, Bruschi S, Coquin L, Schofield J, Feala JD, Reed JC, McCulloch AD, Paternostro G.

PLoS Comput Biol. 2008 Dec;4(12):e1000249. doi: 10.1371/journal.pcbi.1000249. Epub 2008 Dec 26.

11.

Metabolomic and flux-balance analysis of age-related decline of hypoxia tolerance in Drosophila muscle tissue.

Coquin L, Feala JD, McCulloch AD, Paternostro G.

Mol Syst Biol. 2008;4:233. doi: 10.1038/msb.2008.71. Epub 2008 Dec 16.

12.

Discovering regulators of the Drosophila cardiac hypoxia response using automated phenotyping technology.

Feala JD, Omens JH, Paternostro G, McCulloch AD.

Ann N Y Acad Sci. 2008 Mar;1123:169-77. doi: 10.1196/annals.1420.019.

PMID:
18375589
13.

Cyanide produced by human isolates of Pseudomonas aeruginosa contributes to lethality in Drosophila melanogaster.

Broderick KE, Chan A, Balasubramanian M, Feala J, Reed SL, Panda M, Sharma VS, Pilz RB, Bigby TD, Boss GR.

J Infect Dis. 2008 Feb 1;197(3):457-64. doi: 10.1086/525282.

PMID:
18199034
14.

Integrating metabolomics and phenomics with systems models of cardiac hypoxia.

Feala JD, Coquin L, Paternostro G, McCulloch AD.

Prog Biophys Mol Biol. 2008 Jan-Apr;96(1-3):209-25. Epub 2007 Aug 10. Review.

PMID:
17870149
15.

The cobalamin precursor cobinamide detoxifies nitroprusside-generated cyanide.

Broderick KE, Balasubramanian M, Chan A, Potluri P, Feala J, Belke DD, McCulloch A, Sharma VS, Pilz RB, Bigby TD, Boss GR.

Exp Biol Med (Maywood). 2007 Jun;232(6):789-98.

PMID:
17526771
16.
17.

The nitric oxide scavenger cobinamide profoundly improves survival in a Drosophila melanogaster model of bacterial sepsis.

Broderick KE, Feala J, McCulloch A, Paternostro G, Sharma VS, Pilz RB, Boss GR.

FASEB J. 2006 Sep;20(11):1865-73.

PMID:
16940158
18.

A more efficient search strategy for aging genes based on connectivity.

Ferrarini L, Bertelli L, Feala J, McCulloch AD, Paternostro G.

Bioinformatics. 2005 Feb 1;21(3):338-48. Epub 2004 Sep 3.

PMID:
15347572

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