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Items: 1 to 50 of 78

1.

A Role for Tetracycline Selection in Recent Evolution of Agriculture-Associated Clostridium difficile PCR Ribotype 078.

Dingle KE, Didelot X, Quan TP, Eyre DW, Stoesser N, Marwick CA, Coia J, Brown D, Buchanan S, Ijaz UZ, Goswami C, Douce G, Fawley WN, Wilcox MH, Peto TEA, Walker AS, Crook DW.

MBio. 2019 Mar 12;10(2). pii: e02790-18. doi: 10.1128/mBio.02790-18.

2.

Molecular epidemiology of Clostridioides (previously Clostridium) difficile isolates from a university hospital in Minas Gerais, Brazil.

Diniz AN, de Oliveira Júnior CA, Vilela EG, Figueiredo HCP, Rupnik M, Wilcox MH, Fawley WN, Blanc DS, Faria Lobato FC, Silva ROS.

Anaerobe. 2019 Apr;56:34-39. doi: 10.1016/j.anaerobe.2019.01.010. Epub 2019 Jan 29.

PMID:
30703440
3.

Correlation between restriction endonuclease analysis and PCR ribotyping for the identification of Clostridioides (Clostridium) difficile clinical strains.

Kociolek LK, Perdue ER, Fawley WN, Wilcox MH, Gerding DN, Johnson S.

Anaerobe. 2018 Dec;54:1-7. doi: 10.1016/j.anaerobe.2018.07.004. Epub 2018 Aug 3.

4.

Patient and Strain Characteristics Associated With Clostridium difficile Transmission and Adverse Outcomes.

Martin JSH, Eyre DW, Fawley WN, Griffiths D, Davies K, Mawer DPC, Peto TEA, Crook DW, Walker AS, Wilcox MH.

Clin Infect Dis. 2018 Oct 15;67(9):1379-1387. doi: 10.1093/cid/ciy302.

5.

Two Distinct Patterns of Clostridium difficile Diversity Across Europe Indicating Contrasting Routes of Spread.

Eyre DW, Davies KA, Davis G, Fawley WN, Dingle KE, De Maio N, Karas A, Crook DW, Peto TEA, Walker AS, Wilcox MH; EUCLID Study Group.

Clin Infect Dis. 2018 Sep 14;67(7):1035-1044. doi: 10.1093/cid/ciy252.

6.

Subtyping of Clostridium difficile PCR ribotypes 591, 106 and 002, the dominant strain types circulating in Medellin, Colombia.

Salazar CL, Reyes C, Cienfuegos-Gallet AV, Best E, Atehortua S, Sierra P, Correa MM, Fawley WN, Paredes-Sabja D, Wilcox M, Gonzalez A.

PLoS One. 2018 Apr 12;13(4):e0195694. doi: 10.1371/journal.pone.0195694. eCollection 2018.

7.

Molecular, microbiological and clinical characterization of Clostridium difficile isolates from tertiary care hospitals in Colombia.

Salazar CL, Reyes C, Atehortua S, Sierra P, Correa MM, Paredes-Sabja D, Best E, Fawley WN, Wilcox M, González Á.

PLoS One. 2017 Sep 13;12(9):e0184689. doi: 10.1371/journal.pone.0184689. eCollection 2017.

8.

Epidemiology of Clostridium difficile in infants in Oxfordshire, UK: Risk factors for colonization and carriage, and genetic overlap with regional C. difficile infection strains.

Stoesser N, Eyre DW, Quan TP, Godwin H, Pill G, Mbuvi E, Vaughan A, Griffiths D, Martin J, Fawley W, Dingle KE, Oakley S, Wanelik K, Finney JM, Kachrimanidou M, Moore CE, Gorbach S, Riley TV, Crook DW, Peto TEA, Wilcox MH, Walker AS; Modernising Medical Microbiology Informatics Group (MMMIG).

PLoS One. 2017 Aug 16;12(8):e0182307. doi: 10.1371/journal.pone.0182307. eCollection 2017.

9.

Comparison of Control of Clostridium difficile Infection in Six English Hospitals Using Whole-Genome Sequencing.

Eyre DW, Fawley WN, Rajgopal A, Settle C, Mortimer K, Goldenberg SD, Dawson S, Crook DW, Peto TEA, Walker AS, Wilcox MH.

Clin Infect Dis. 2017 Aug 1;65(3):433-441. doi: 10.1093/cid/cix338.

10.

Contribution to Clostridium Difficile Transmission of Symptomatic Patients With Toxigenic Strains Who Are Fecal Toxin Negative.

Mawer DPC, Eyre DW, Griffiths D, Fawley WN, Martin JSH, Quan TP, Peto TEA, Crook DW, Walker AS, Wilcox MH.

Clin Infect Dis. 2017 May 1;64(9):1163-1170. doi: 10.1093/cid/cix079.

11.

Effects of control interventions on Clostridium difficile infection in England: an observational study.

Dingle KE, Didelot X, Quan TP, Eyre DW, Stoesser N, Golubchik T, Harding RM, Wilson DJ, Griffiths D, Vaughan A, Finney JM, Wyllie DH, Oakley SJ, Fawley WN, Freeman J, Morris K, Martin J, Howard P, Gorbach S, Goldstein EJC, Citron DM, Hopkins S, Hope R, Johnson AP, Wilcox MH, Peto TEA, Walker AS, Crook DW; Modernising Medical Microbiology Informatics Group.

Lancet Infect Dis. 2017 Apr;17(4):411-421. doi: 10.1016/S1473-3099(16)30514-X. Epub 2017 Jan 25.

12.

Enhanced surveillance of Clostridium difficile infection occurring outside hospital, England, 2011 to 2013.

Fawley WN, Davies KA, Morris T, Parnell P, Howe R, Wilcox MH; Clostridium difficile Ribotyping Network (CDRN) Working Group.

Euro Surveill. 2016 Jul 21;21(29). doi: 10.2807/1560-7917.ES.2016.21.29.30295.

13.

Predominance of Clostridium difficile ribotypes 012, 027 and 046 in a university hospital in Chile, 2012.

Plaza-Garrido Á, Barra-Carrasco J, Macias JH, Carman R, Fawley WN, Wilcox MH, Hernández-Rocha C, Guzmán-Durán AM, Alvarez-Lobos M, Paredes-Sabja D.

Epidemiol Infect. 2016 Apr;144(5):976-9. doi: 10.1017/S0950268815002459. Epub 2015 Oct 22.

PMID:
26489717
14.

Outcome of relapsing Clostridium difficile infections do not correlate with virulence-, spore- and vegetative cell-associated phenotypes.

Plaza-Garrido Á, Miranda-Cárdenas C, Castro-Córdova P, Olguín-Araneda V, Cofré-Araneda G, Hernández-Rocha C, Carman R, Ibáñez P, Fawley WN, Wilcox MH, Gil F, Calderón IL, Fuentes JA, Guzmán-Durán AM, Alvarez-Lobos M, Paredes-Sabja D.

Anaerobe. 2015 Dec;36:30-8. doi: 10.1016/j.anaerobe.2015.09.005. Epub 2015 Sep 25.

PMID:
26403333
15.

The FERMI free-electron lasers.

Allaria E, Badano L, Bassanese S, Capotondi F, Castronovo D, Cinquegrana P, Danailov MB, D'Auria G, Demidovich A, De Monte R, De Ninno G, Di Mitri S, Diviacco B, Fawley WM, Ferianis M, Ferrari E, Gaio G, Gauthier D, Giannessi L, Iazzourene F, Kurdi G, Mahne N, Nikolov I, Parmigiani F, Penco G, Raimondi L, Rebernik P, Rossi F, Roussel E, Scafuri C, Serpico C, Sigalotti P, Spezzani C, Svandrlik M, Svetina C, Trovó M, Veronese M, Zangrando D, Zangrando M.

J Synchrotron Radiat. 2015 May;22(3):485-91. doi: 10.1107/S1600577515005366. Epub 2015 Apr 21.

PMID:
25931057
16.

Emergence and spread of predominantly community-onset Clostridium difficile PCR ribotype 244 infection in Australia, 2010 to 2012.

Eyre DW, Tracey L, Elliott B, Slimings C, Huntington PG, Stuart RL, Korman TM, Kotsiou G, McCann R, Griffiths D, Fawley WN, Armstrong P, Dingle KE, Walker AS, Peto TE, Crook DW, Wilcox MH, Riley TV.

Euro Surveill. 2015 Mar 12;20(10):21059.

17.

Development and validation of an internationally-standardized, high-resolution capillary gel-based electrophoresis PCR-ribotyping protocol for Clostridium difficile.

Fawley WN, Knetsch CW, MacCannell DR, Harmanus C, Du T, Mulvey MR, Paulick A, Anderson L, Kuijper EJ, Wilcox MH.

PLoS One. 2015 Feb 13;10(2):e0118150. doi: 10.1371/journal.pone.0118150. eCollection 2015.

18.

Clostridium difficile ribotype 126 in southern Taiwan: a cluster of three symptomatic cases.

Hung YP, Lin HJ, Tsai BY, Liu HC, Liu HC, Lee JC, Wu YH, Wilcox MH, Fawley WN, Hsueh PR, Tsai PJ, Ko WC.

Anaerobe. 2014 Dec;30:188-92. doi: 10.1016/j.anaerobe.2014.06.005. Epub 2014 Jun 21.

PMID:
24956433
19.

Impact of non-Gaussian electron energy heating upon the performance of a seeded free-electron laser.

Ferrari E, Allaria E, Fawley W, Giannessi L, Huang Z, Penco G, Spampinati S.

Phys Rev Lett. 2014 Mar 21;112(11):114802. Epub 2014 Mar 21.

PMID:
24702379
20.

Experimental demonstration of electron longitudinal-phase-space linearization by shaping the photoinjector laser pulse.

Penco G, Danailov M, Demidovich A, Allaria E, De Ninno G, Di Mitri S, Fawley WM, Ferrari E, Giannessi L, Trovó M.

Phys Rev Lett. 2014 Jan 31;112(4):044801. Epub 2014 Jan 31.

PMID:
24580459
21.

Evolutionary history of the Clostridium difficile pathogenicity locus.

Dingle KE, Elliott B, Robinson E, Griffiths D, Eyre DW, Stoesser N, Vaughan A, Golubchik T, Fawley WN, Wilcox MH, Peto TE, Walker AS, Riley TV, Crook DW, Didelot X.

Genome Biol Evol. 2014 Jan;6(1):36-52. doi: 10.1093/gbe/evt204.

22.

Comparison of multilocus variable-number tandem-repeat analysis and whole-genome sequencing for investigation of Clostridium difficile transmission.

Eyre DW, Fawley WN, Best EL, Griffiths D, Stoesser NE, Crook DW, Peto TE, Walker AS, Wilcox MH.

J Clin Microbiol. 2013 Dec;51(12):4141-9. doi: 10.1128/JCM.01095-13. Epub 2013 Oct 9.

23.

Two-colour generation in a chirped seeded free-electron laser: a close look.

Mahieu B, Allaria E, Castronovo D, Danailov MB, Demidovich A, De Ninno G, Di Mitri S, Fawley WM, Ferrari E, Fröhlich L, Gauthier D, Giannessi L, Mahne N, Penco G, Raimondi L, Spampinati S, Spezzani C, Svetina C, Trovò M, Zangrando M.

Opt Express. 2013 Sep 23;21(19):22728-41. doi: 10.1364/OE.21.022728.

PMID:
24104160
24.

Two-colour pump-probe experiments with a twin-pulse-seed extreme ultraviolet free-electron laser.

Allaria E, Bencivenga F, Borghes R, Capotondi F, Castronovo D, Charalambous P, Cinquegrana P, Danailov MB, De Ninno G, Demidovich A, Di Mitri S, Diviacco B, Fausti D, Fawley WM, Ferrari E, Froehlich L, Gauthier D, Gessini A, Giannessi L, Ivanov R, Kiskinova M, Kurdi G, Mahieu B, Mahne N, Nikolov I, Masciovecchio C, Pedersoli E, Penco G, Raimondi L, Serpico C, Sigalotti P, Spampinati S, Spezzani C, Svetina C, Trovò M, Zangrando M.

Nat Commun. 2013;4:2476. doi: 10.1038/ncomms3476.

25.

Escherichia coli bacteraemia: 2 years of prospective regional surveillance (2010-12).

Horner C, Fawley W, Morris K, Parnell P, Denton M, Wilcox M.

J Antimicrob Chemother. 2014 Jan;69(1):91-100. doi: 10.1093/jac/dkt333. Epub 2013 Sep 3.

PMID:
24003184
26.

Short-term genome stability of serial Clostridium difficile ribotype 027 isolates in an experimental gut model and recurrent human disease.

Eyre DW, Walker AS, Freeman J, Baines SD, Fawley WN, Chilton CH, Griffiths D, Vaughan A, Crook DW, Peto TE, Wilcox MH.

PLoS One. 2013 May 15;8(5):e63540. doi: 10.1371/journal.pone.0063540. Print 2013.

27.

Mixed infection by Clostridium difficile in an in vitro model of the human gut.

Baines SD, Crowther GS, Todhunter SL, Freeman J, Chilton CH, Fawley WN, Wilcox MH.

J Antimicrob Chemother. 2013 May;68(5):1139-43. doi: 10.1093/jac/dks529. Epub 2013 Jan 25.

PMID:
23354280
28.

Recombinational switching of the Clostridium difficile S-layer and a novel glycosylation gene cluster revealed by large-scale whole-genome sequencing.

Dingle KE, Didelot X, Ansari MA, Eyre DW, Vaughan A, Griffiths D, Ip CL, Batty EM, Golubchik T, Bowden R, Jolley KA, Hood DW, Fawley WN, Walker AS, Peto TE, Wilcox MH, Crook DW.

J Infect Dis. 2013 Feb 15;207(4):675-86. doi: 10.1093/infdis/jis734. Epub 2012 Nov 29.

29.

Morbidity and mortality associated with Clostridium difficile ribotype 078: a case-case study.

Patterson L, Wilcox MH, Fawley WN, Verlander NQ, Geoghegan L, Patel BC, Wyatt T, Smyth B.

J Hosp Infect. 2012 Oct;82(2):125-8. doi: 10.1016/j.jhin.2012.07.011. Epub 2012 Sep 1.

PMID:
22947650
30.

Oritavancin does not induce Clostridium difficile germination and toxin production in hamsters or a human gut model.

Freeman J, Marquis M, Crowther GS, Todhunter SL, Fawley WN, Chilton CH, Moeck G, Lehoux D, Wilcox MH.

J Antimicrob Chemother. 2012 Dec;67(12):2919-26. doi: 10.1093/jac/dks309. Epub 2012 Aug 16.

PMID:
22899803
31.

Changing epidemiology of Clostridium difficile infection following the introduction of a national ribotyping-based surveillance scheme in England.

Wilcox MH, Shetty N, Fawley WN, Shemko M, Coen P, Birtles A, Cairns M, Curran MD, Dodgson KJ, Green SM, Hardy KJ, Hawkey PM, Magee JG, Sails AD, Wren MW.

Clin Infect Dis. 2012 Oct;55(8):1056-63. Epub 2012 Jul 11.

PMID:
22784871
32.

Renal failure and leukocytosis are predictors of a complicated course of Clostridium difficile infection if measured on day of diagnosis.

Bauer MP, Hensgens MP, Miller MA, Gerding DN, Wilcox MH, Dale AP, Fawley WN, Kuijper EJ, Gorbach SL.

Clin Infect Dis. 2012 Aug;55 Suppl 2:S149-53. doi: 10.1093/cid/cis340.

33.

Epidemiology of Clostridium difficile infections in a tertiary-care hospital in Korea.

Kim J, Kang JO, Kim H, Seo MR, Choi TY, Pai H, Kuijper EJ, Sanders I, Fawley W.

Clin Microbiol Infect. 2013 Jun;19(6):521-7. doi: 10.1111/j.1469-0691.2012.03910.x. Epub 2012 Jun 19.

34.

Diverse temperate bacteriophage carriage in Clostridium difficile 027 strains.

Nale JY, Shan J, Hickenbotham PT, Fawley WN, Wilcox MH, Clokie MR.

PLoS One. 2012;7(5):e37263. doi: 10.1371/journal.pone.0037263. Epub 2012 May 18.

35.

An enhanced DNA fingerprinting service to investigate potential Clostridium difficile infection case clusters sharing the same PCR ribotype.

Fawley WN, Wilcox MH; Clostridium difficile Ribotyping Network for England and Northern Ireland.

J Clin Microbiol. 2011 Dec;49(12):4333-7. doi: 10.1128/JCM.05873-11. Epub 2011 Sep 28.

36.

Clinical Clostridium difficile: clonality and pathogenicity locus diversity.

Dingle KE, Griffiths D, Didelot X, Evans J, Vaughan A, Kachrimanidou M, Stoesser N, Jolley KA, Golubchik T, Harding RM, Peto TE, Fawley W, Walker AS, Wilcox M, Crook DW.

PLoS One. 2011;6(5):e19993. doi: 10.1371/journal.pone.0019993. Epub 2011 May 19.

37.

Monomicrobial Clostridium difficile bacteraemias and relationship to gut infection.

McGill F, Fawley WN, Wilcox MH.

J Hosp Infect. 2011 Feb;77(2):170-1. doi: 10.1016/j.jhin.2010.06.024. Epub 2010 Dec 3. No abstract available.

PMID:
21129818
38.

Relatedness of human and animal Clostridium difficile PCR ribotype 078 isolates determined on the basis of multilocus variable-number tandem-repeat analysis and tetracycline resistance.

Bakker D, Corver J, Harmanus C, Goorhuis A, Keessen EC, Fawley WN, Wilcox MH, Kuijper EJ.

J Clin Microbiol. 2010 Oct;48(10):3744-9. doi: 10.1128/JCM.01171-10. Epub 2010 Aug 4.

39.

Infection due to C. difficile ribotype 078: first report of cases in the Republic of Ireland.

Burns K, Morris-Downes M, Fawley WN, Smyth E, Wilcox MH, Fitzpatrick F.

J Hosp Infect. 2010 Aug;75(4):287-91. doi: 10.1016/j.jhin.2010.03.025. Epub 2010 Jun 17.

PMID:
20621236
40.

The changing epidemiology of Clostridium difficile infections.

Freeman J, Bauer MP, Baines SD, Corver J, Fawley WN, Goorhuis B, Kuijper EJ, Wilcox MH.

Clin Microbiol Rev. 2010 Jul;23(3):529-49. doi: 10.1128/CMR.00082-09. Review.

41.

The potential for airborne dispersal of Clostridium difficile from symptomatic patients.

Best EL, Fawley WN, Parnell P, Wilcox MH.

Clin Infect Dis. 2010 Jun 1;50(11):1450-7. doi: 10.1086/652648.

PMID:
20415567
42.

Multilocus sequence typing of Clostridium difficile.

Griffiths D, Fawley W, Kachrimanidou M, Bowden R, Crook DW, Fung R, Golubchik T, Harding RM, Jeffery KJ, Jolley KA, Kirton R, Peto TE, Rees G, Stoesser N, Vaughan A, Walker AS, Young BC, Wilcox M, Dingle KE.

J Clin Microbiol. 2010 Mar;48(3):770-8. doi: 10.1128/JCM.01796-09. Epub 2009 Dec 30.

43.

Emergence of reduced susceptibility to metronidazole in Clostridium difficile.

Baines SD, O'Connor R, Freeman J, Fawley WN, Harmanus C, Mastrantonio P, Kuijper EJ, Wilcox MH.

J Antimicrob Chemother. 2008 Nov;62(5):1046-52. doi: 10.1093/jac/dkn313. Epub 2008 Aug 7.

PMID:
18693234
44.

A case-control study of community-associated Clostridium difficile infection.

Wilcox MH, Mooney L, Bendall R, Settle CD, Fawley WN.

J Antimicrob Chemother. 2008 Aug;62(2):388-96. doi: 10.1093/jac/dkn163. Epub 2008 Apr 22.

PMID:
18434341
45.

Use of highly discriminatory fingerprinting to analyze clusters of Clostridium difficile infection cases due to epidemic ribotype 027 strains.

Fawley WN, Freeman J, Smith C, Harmanus C, van den Berg RJ, Kuijper EJ, Wilcox MH.

J Clin Microbiol. 2008 Mar;46(3):954-60. doi: 10.1128/JCM.01764-07. Epub 2008 Jan 23.

46.

Viral gastroenteritis increases the reports of Clostridium difficile infection.

Wilcox M, Fawley W.

J Hosp Infect. 2007 Aug;66(4):395-6. Epub 2007 Jul 27. No abstract available.

PMID:
17662506
47.

Efficacy of hospital cleaning agents and germicides against epidemic Clostridium difficile strains.

Fawley WN, Underwood S, Freeman J, Baines SD, Saxton K, Stephenson K, Owens RC Jr, Wilcox MH.

Infect Control Hosp Epidemiol. 2007 Aug;28(8):920-5. Epub 2007 Jun 15.

PMID:
17620238
48.

Measurement of toxin production by Clostridium difficile.

Freeman J, Fawley W, Baines S, Wilcox M.

Lancet. 2006 Mar 25;367(9515):982-3; author reply 983-4. No abstract available.

PMID:
16564352
49.

Surveillance for mupirocin resistance following introduction of routine peri-operative prophylaxis with nasal mupirocin.

Fawley WN, Parnell P, Hall J, Wilcox MH.

J Hosp Infect. 2006 Mar;62(3):327-32. Epub 2005 Dec 27.

PMID:
16377029
50.

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