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Items: 14


Evidence for positive allosteric modulation of cognitive-enhancing effects of nicotine in healthy human subjects.

Hahn B, Shrieves ME, Olmstead CK, Yuille MB, Chiappelli JJ, Pereira EFR, Albuquerque EX, Fawcett WP.

Psychopharmacology (Berl). 2020 Jan;237(1):219-230. doi: 10.1007/s00213-019-05363-4. Epub 2019 Nov 4.


Developmental neurotoxicity of the organophosphorus insecticide chlorpyrifos: from clinical findings to preclinical models and potential mechanisms.

Burke RD, Todd SW, Lumsden E, Mullins RJ, Mamczarz J, Fawcett WP, Gullapalli RP, Randall WR, Pereira EFR, Albuquerque EX.

J Neurochem. 2017 Aug;142 Suppl 2:162-177. doi: 10.1111/jnc.14077. Review.


Spatial learning impairment in prepubertal guinea pigs prenatally exposed to the organophosphorus pesticide chlorpyrifos: Toxicological implications.

Mamczarz J, Pescrille JD, Gavrushenko L, Burke RD, Fawcett WP, DeTolla LJ Jr, Chen H, Pereira EFR, Albuquerque EX.

Neurotoxicology. 2016 Sep;56:17-28. doi: 10.1016/j.neuro.2016.06.008. Epub 2016 Jun 11.


Acute toxicity of organophosphorus compounds in guinea pigs is sex- and age-dependent and cannot be solely accounted for by acetylcholinesterase inhibition.

Fawcett WP, Aracava Y, Adler M, Pereira EF, Albuquerque EX.

J Pharmacol Exp Ther. 2009 Feb;328(2):516-24. doi: 10.1124/jpet.108.146639. Epub 2008 Nov 4.


Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents.

Albuquerque EX, Pereira EF, Aracava Y, Fawcett WP, Oliveira M, Randall WR, Hamilton TA, Kan RK, Romano JA Jr, Adler M.

Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13220-5. Epub 2006 Aug 16.


Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus.

Alkondon M, Pereira EF, Yu P, Arruda EZ, Almeida LE, Guidetti P, Fawcett WP, Sapko MT, Randall WR, Schwarcz R, Tagle DA, Albuquerque EX.

J Neurosci. 2004 May 12;24(19):4635-48.


Low concentrations of pyridostigmine prevent soman-induced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors.

Santos MD, Pereira EF, Aracava Y, Castro NG, Fawcett WP, Randall WR, Albuquerque EX.

J Pharmacol Exp Ther. 2003 Jan;304(1):254-65.


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