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An electroencephalographic signature predicts antidepressant response in major depression.

Wu W, Zhang Y, Jiang J, Lucas MV, Fonzo GA, Rolle CE, Cooper C, Chin-Fatt C, Krepel N, Cornelssen CA, Wright R, Toll RT, Trivedi HM, Monuszko K, Caudle TL, Sarhadi K, Jha MK, Trombello JM, Deckersbach T, Adams P, McGrath PJ, Weissman MM, Fava M, Pizzagalli DA, Arns M, Trivedi MH, Etkin A.

Nat Biotechnol. 2020 Feb 10. doi: 10.1038/s41587-019-0397-3. [Epub ahead of print]


All Suicidal Ideation Is Not Created Equal: Two Cases of Suicide Attempts During Maintenance Ketamine Treatment.

Cusin C, Sakurai H, Bentley K, Pedrelli P, Foster S, Fava M, Mischoulon D.

Am J Psychiatry. 2020 Feb 1;177(2):173-174. doi: 10.1176/appi.ajp.2019.19050508. No abstract available.


Success and efficiency of phase 2/3 adjunctive trials for MDD funded by industry: a systematic review.

Salloum NC, Fava M, Ball S, Papakostas GI.

Mol Psychiatry. 2020 Jan 27. doi: 10.1038/s41380-020-0646-3. [Epub ahead of print] Review.


Comparison of three therapeutic regimens for genotype-3 hepatitis C virus infection in a large real-life multicentre cohort.

Soria A, Fava M, Bernasconi DP, Lapadula G, Colella E, Valsecchi MG, Migliorino GM, D'Ambrosio R, Landonio S, Schiavini M, Spinetti A, Carriero C, Degasperi E, Cologni G, Gatti F, Viganò P, Hasson H, Uberti-Foppa C, Pasulo L, Baiguera C, Rossotti R, Vinci M, Puoti M, Giorgini A, Menzaghi B, Lombardi A, Pan A, Aghemo A, Grossi PA, Boldizzoni R, Colombo S, Viganò M, Rumi MG, Del Poggio P, Valenti L, Giglio O, De Bona A, d'Arminio Monforte A, Colombo A, Spinelli O, Pigozzi MG, Molteni C, Bonfanti P, Terreni N, Perini P, Capretti A, Bella D, Liani C, Polo S, Aimo G, Pagnucco L, Bhoori S, Centenaro R, Graffeo M, Ciaccio A, Dionigi E, Lazzaroni S, Carderi I, Di Marco M, Rizzardini G, Noventa F, Lampertico P, Fagiuoli S.

Liver Int. 2020 Jan 22. doi: 10.1111/liv.14386. [Epub ahead of print]


Predictive factors of diagnostic conversion from major depressive disorder to bipolar disorder in young adults ages 19-34: A nationwide population study in South Korea.

Kim H, Kim Y, Baek JH, Fava M, Mischoulon D, Nierenberg AA, Choi KW, Na EJ, Shin MH, Jeon HJ.

J Affect Disord. 2020 Jan 7;265:52-58. doi: 10.1016/j.jad.2020.01.009. [Epub ahead of print]


Elevated Amygdala Activity in Young Adults With Familial Risk for Depression: A Potential Marker of Low Resilience.

Barbour T, Holmes AJ, Farabaugh AH, DeCross SN, Coombs G, Boeke EA, Wolthusen RPF, Nyer M, Pedrelli P, Fava M, Holt DJ.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Feb;5(2):194-202. doi: 10.1016/j.bpsc.2019.10.010. Epub 2019 Nov 6.


Anxiety Symptoms Questionnaire (ASQ): development and validation.

Baker A, Simon N, Keshaviah A, Farabaugh A, Deckersbach T, Worthington JJ, Hoge E, Fava M, Pollack MP.

Gen Psychiatr. 2019 Dec 18;32(6):e100144. doi: 10.1136/gpsych-2019-100144. eCollection 2019.


Cortical Connectivity Moderators of Antidepressant vs Placebo Treatment Response in Major Depressive Disorder: Secondary Analysis of a Randomized Clinical Trial.

Rolle CE, Fonzo GA, Wu W, Toll R, Jha MK, Cooper C, Chin-Fatt C, Pizzagalli DA, Trombello JM, Deckersbach T, Fava M, Weissman MM, Trivedi MH, Etkin A.

JAMA Psychiatry. 2020 Jan 2. doi: 10.1001/jamapsychiatry.2019.3867. [Epub ahead of print]


Evaluating the combination of a Brief Motivational Intervention plus Cognitive Behavioral Therapy for Depression and heavy episodic drinking in college students.

Pedrelli P, Fisher LB, Nyer M, Shapero BG, Farabaugh A, Hayden ER, Levine MT, Fava M, Weiss RD, Borsari B, Merrill JE.

Psychol Addict Behav. 2019 Dec 19. doi: 10.1037/adb0000538. [Epub ahead of print]


The allopregnanolone to progesterone ratio across the menstrual cycle and in menopause.

Kimball A, Dichtel LE, Nyer MB, Mischoulon D, Fisher LB, Cusin C, Dording CM, Trinh NH, Yeung A, Haines MS, Sung JC, Pinna G, Rasmusson AM, Carpenter LL, Fava M, Klibanski A, Miller KK.

Psychoneuroendocrinology. 2020 Feb;112:104512. doi: 10.1016/j.psyneuen.2019.104512. Epub 2019 Nov 14.


A randomized controlled pilot study of ulipristal acetate for abnormal bleeding among women using the 52-mg levonorgestrel intrauterine system.

Fava M, Peloggia A, Baccaro LF, Castro S, Carvalho N, Bahamondes L.

Int J Gynaecol Obstet. 2019 Nov 28. doi: 10.1002/ijgo.13068. [Epub ahead of print]


Dose increase of S-Adenosyl-Methionine and escitalopram in a randomized clinical trial for major depressive disorder.

Sakurai H, L Carpenter L, R Tyrka A, Price LH, I Papakostas G, Dording CM, Yeung AS, Cusin C, Ludington E, Bernard-Negron R, Fava M, Mischoulon D.

J Affect Disord. 2020 Feb 1;262:118-125. doi: 10.1016/j.jad.2019.10.040. Epub 2019 Oct 31.


Rising placebo response rates threaten the validity of antipsychotic meta-analyses.

Dotson S, Mischoulon D, Lee H, Fava M.

Ann Clin Psychiatry. 2019 Nov;31(4):249-259.


Pre-treatment peripheral biomarkers associated with treatment response in panic symptoms in patients with major depressive disorder and panic disorder: A 12-week follow-up study.

Kim K, Jang EH, Kim AY, Fava M, Mischoulon D, Papakostas GI, Kim H, Na EJ, Yu HY, Jeon HJ.

Compr Psychiatry. 2019 Nov;95:152140. doi: 10.1016/j.comppsych.2019.152140. Epub 2019 Oct 19.


Risks of suicide attempts after prescription of zolpidem in people with depression: A nationwide population study in South Korea.

Kim H, Kim Y, Myung W, Fava M, Mischoulon D, Lee U, Lee H, Na EJ, Choi KW, Shin MH, Jeon HJ.

Sleep. 2019 Oct 5. pii: zsz235. doi: 10.1093/sleep/zsz235. [Epub ahead of print]


WITHDRAWN: Size Does Matter, But It Isn't Everything: The Challenge of Modest Treatment Effects in Chronic Pain Clinical Trials.

Smith SM, Fava M, Jensen MP, Mbowe OB, McDermott MP, Turk DC, Dworkin RH.

J Pain. 2019 Sep 30. pii: S1526-5900(19)30816-8. doi: 10.1016/j.jpain.2019.09.008. [Epub ahead of print]


A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of Adjunctive Pimavanserin in Patients With Major Depressive Disorder and an Inadequate Response to Therapy (CLARITY).

Fava M, Dirks B, Freeman MP, Papakostas GI, Shelton RC, Thase ME, Trivedi MH, Liu K, Stankovic S.

J Clin Psychiatry. 2019 Sep 24;80(6). pii: 19m12928. doi: 10.4088/JCP.19m12928.


Brain regulation of emotional conflict predicts antidepressant treatment response for depression.

Fonzo GA, Etkin A, Zhang Y, Wu W, Cooper C, Chin-Fatt C, Jha MK, Trombello J, Deckersbach T, Adams P, McInnis M, McGrath PJ, Weissman MM, Fava M, Trivedi MH.

Nat Hum Behav. 2019 Dec;3(12):1319-1331. doi: 10.1038/s41562-019-0732-1. Epub 2019 Sep 23.


Optimal dosing of antidepressant drugs.

Burchi E, Fava M.

Lancet Psychiatry. 2019 Oct;6(10):805-806. doi: 10.1016/S2215-0366(19)30303-7. No abstract available.


Effect of Intrinsic Patterns of Functional Brain Connectivity in Moderating Antidepressant Treatment Response in Major Depression.

Chin Fatt CR, Jha MK, Cooper CM, Fonzo G, South C, Grannemann B, Carmody T, Greer TL, Kurian B, Fava M, McGrath PJ, Adams P, McInnis M, Parsey RV, Weissman M, Phillips ML, Etkin A, Trivedi MH.

Am J Psychiatry. 2020 Feb 1;177(2):143-154. doi: 10.1176/appi.ajp.2019.18070870. Epub 2019 Sep 20.


Paranoid Ideation Without Psychosis Is Associated With Depression, Anxiety, and Suicide Attempts in General Population.

Na EJ, Choi KW, Hong JP, Cho MJ, Fava M, Mischoulon D, Jeon HJ.

J Nerv Ment Dis. 2019 Oct;207(10):826-831. doi: 10.1097/NMD.0000000000001050.


Time to relapse after a single administration of intravenous ketamine augmentation in unipolar treatment-resistant depression.

Salloum NC, Fava M, Hock RS, Freeman MP, Flynn M, Hoeppner B, Cusin C, Iosifescu DV, Trivedi MH, Sanacora G, Mathew SJ, Debattista C, Ionescu DF, Papakostas GI.

J Affect Disord. 2020 Jan 1;260:131-139. doi: 10.1016/j.jad.2019.09.017. Epub 2019 Sep 3.


Ratio of plasma BDNF to leptin levels are associated with treatment response in major depressive disorder but not in panic disorder: A 12-week follow-up study.

An JH, Jang EH, Kim AY, Fava M, Mischoulon D, Papakostas GI, Na EJ, Jang J, Yu HY, Hong JP, Jeon HJ.

J Affect Disord. 2019 Dec 1;259:349-354. doi: 10.1016/j.jad.2019.08.021. Epub 2019 Aug 14.


Reward related ventral striatal activity and differential response to sertraline versus placebo in depressed individuals.

Greenberg T, Fournier JC, Stiffler R, Chase HW, Almeida JR, Aslam H, Deckersbach T, Cooper C, Toups MS, Carmody T, Kurian B, Peltier S, Adams P, McInnis MG, Oquendo MA, Fava M, Parsey R, McGrath PJ, Weissman M, Trivedi M, Phillips ML.

Mol Psychiatry. 2019 Aug 28. doi: 10.1038/s41380-019-0490-5. [Epub ahead of print]


Design and Methods of the Korean National Investigations of 70,000 Suicide Victims Through Police Records (The KNIGHTS Study).

Na EJ, Choi J, Kim D, Kwon H, Lee Y, Lee G, Fava M, Mischoulon D, Jang J, Jeon HJ.

Psychiatry Investig. 2019 Oct;16(10):777-788. doi: 10.30773/pi.2019.07.14. Epub 2019 Aug 29.


Obesity and cardio-metabolic health.

Fava MC, Agius R, Fava S.

Br J Hosp Med (Lond). 2019 Aug 2;80(8):466-471. doi: 10.12968/hmed.2019.80.8.466. Review. Erratum in: Br J Hosp Med (Lond). 2019 Oct 2;80(10):619.


Increased Morbidity of Major Depressive Disorder After Thyroidectomy: A Nationwide Population-Based Study in South Korea.

Choi KW, Kim Y, Fava M, Mischoulon D, Na EJ, Kim SW, Shin MH, Chung MK, Jeon HJ.

Thyroid. 2019 Dec;29(12):1713-1722. doi: 10.1089/thy.2019.0091. Epub 2019 Sep 19.


Longer-term open-label study of adjunctive riluzole in treatment-resistant depression.

Sakurai H, Dording C, Yeung A, Foster S, Jain F, Chang T, Trinh NH, Bernard R, Boyden S, Iqbal SZ, Wilkinson ST, Mathew SJ, Mischoulon D, Fava M, Cusin C.

J Affect Disord. 2019 Nov 1;258:102-108. doi: 10.1016/j.jad.2019.06.065. Epub 2019 Jul 2.


Model-Informed Approach to Assess the Treatment Effect Conditional to the Level of Placebo Response.

Gomeni R, Rabinowitz J, Goyal N, Bressolle-Gomeni FMM, Fava M.

Clin Pharmacol Ther. 2019 Dec;106(6):1253-1260. doi: 10.1002/cpt.1584. Epub 2019 Aug 30.


Discovery and replication of cerebral blood flow differences in major depressive disorder.

Cooper CM, Chin Fatt CR, Liu P, Grannemann BD, Carmody T, Almeida JRC, Deckersbach T, Fava M, Kurian BT, Malchow AL, McGrath PJ, McInnis M, Oquendo MA, Parsey RV, Bartlett E, Weissman M, Phillips ML, Lu H, Trivedi MH.

Mol Psychiatry. 2019 Aug 6. doi: 10.1038/s41380-019-0464-7. [Epub ahead of print]


Monthly Extended-Release Risperidone (RBP-7000) in the Treatment of Schizophrenia: Results From the Phase 3 Program.

Andorn A, Graham J, Csernansky J, Newcomer JW, Shinde S, Muma G, Heidbreder C, Fava M.

J Clin Psychopharmacol. 2019 Sep/Oct;39(5):428-433. doi: 10.1097/JCP.0000000000001076.


Glycoproteomic Analysis of the Aortic Extracellular Matrix in Marfan Patients.

Yin 殷晓科 X, Wanga S, Fellows AL, Barallobre-Barreiro J, Lu R, Davaapil H, Franken R, Fava M, Baig F, Skroblin P, Xing Q, Koolbergen DR, Groenink M, Zwinderman AH, Balm R, de Vries CJM, Mulder BJM, Viner R, Jahangiri M, Reinhardt DP, Sinha S, de Waard V, Mayr M.

Arterioscler Thromb Vasc Biol. 2019 Sep;39(9):1859-1873. doi: 10.1161/ATVBAHA.118.312175. Epub 2019 Jul 18.


Effect of Korean Red Ginseng in individuals exposed to high stress levels: a 6-week, double-blind, randomized, placebo-controlled trial.

Baek JH, Heo JY, Fava M, Mischoulon D, Choi KW, Na EJ, Cho H, Jeon HJ.

J Ginseng Res. 2019 Jul;43(3):402-407. doi: 10.1016/j.jgr.2018.03.001. Epub 2018 Mar 8.


Patient-reported outcomes in schizophrenia patients treated with once-monthly extended-release risperidone in a long-term clinical study.

Dhanda R, Varghese D, Nadipelli VR, Fava M, Joshi N, Solem CT, Graham JA, Learned SM, Heidbreder C.

Patient Prefer Adherence. 2019 Jul 2;13:1037-1050. doi: 10.2147/PPA.S202173. eCollection 2019.


Efficacy and Safety of Fixed-Dose Esketamine Nasal Spray Combined With a New Oral Antidepressant in Treatment-Resistant Depression: Results of a Randomized, Double-Blind, Active-Controlled Study (TRANSFORM-1).

Fedgchin M, Trivedi M, Daly EJ, Melkote R, Lane R, Lim P, Vitagliano D, Blier P, Fava M, Liebowitz M, Ravindran A, Gaillard R, Ameele HVD, Preskorn S, Manji H, Hough D, Drevets WC, Singh JB.

Int J Neuropsychopharmacol. 2019 Oct 1;22(10):616-630. doi: 10.1093/ijnp/pyz039.


Community-Delivered Heated Hatha Yoga as a Treatment for Depressive Symptoms: An Uncontrolled Pilot Study.

Nyer M, Hopkins LB, Farabaugh A, Nauphal M, Parkin S, McKee MM, Miller KK, Streeter C, Uebelacker LA, Fava M, Alpert JE, Pedrelli P, Mischoulon D.

J Altern Complement Med. 2019 Aug;25(8):814-823. doi: 10.1089/acm.2018.0365. Epub 2019 Jul 10.


Results from a long-term open-label extension study of adjunctive buprenorphine/samidorphan combination in patients with major depressive disorder.

Thase ME, Stanford AD, Memisoglu A, Martin W, Claxton A, Bodkin JA, Trivedi MH, Fava M, Yu M, Pathak S.

Neuropsychopharmacology. 2019 Dec;44(13):2268-2276. doi: 10.1038/s41386-019-0451-3. Epub 2019 Jun 29.


Cerebral Blood Perfusion Predicts Response to Sertraline versus Placebo for Major Depressive Disorder in the EMBARC Trial.

Cooper CM, Chin Fatt CR, Jha M, Fonzo GA, Grannemann BD, Carmody T, Ali A, Aslan S, Almeida JRC, Deckersbach T, Fava M, Kurian BT, McGrath PJ, McInnis M, Parsey RV, Weissman M, Phillips ML, Lu H, Etkin A, Trivedi MH.

EClinicalMedicine. 2019 May 18;10:32-41. doi: 10.1016/j.eclinm.2019.04.007. eCollection 2019 Apr.


Mandibular radiomorphometric assessment of bone mineral density in survivors of pediatric hematopoietic stem-cell transplantation.

Frascino AV, Costa C, Salgado DMRA, Coracin FL, Fava M, Odone-Filho V.

Clinics (Sao Paulo). 2019;74:e929. doi: 10.6061/clinics/2019/e929. Epub 2019 May 30.


Examining raphe-amygdala structural connectivity as a biological predictor of SSRI response.

Pillai RLI, Huang C, LaBella A, Zhang M, Yang J, Trivedi M, Weissman M, McGrath P, Fava M, Kurian B, Cooper C, McInnis M, Oquendo MA, Pizzagalli DA, Parsey RV, DeLorenzo C.

J Affect Disord. 2019 Sep 1;256:8-16. doi: 10.1016/j.jad.2019.05.055. Epub 2019 May 28.


Deformities of the Globus Pallidus are Associated with Severity of Suicidal Ideation and Impulsivity in Patients with Major Depressive Disorder.

Kim K, Shin JH, Myung W, Fava M, Mischoulon D, Papakostas GI, Choi KW, Na EJ, Seo SW, Seong JK, Jeon HJ.

Sci Rep. 2019 May 16;9(1):7462. doi: 10.1038/s41598-019-43882-4.


Risks of Completed Suicide of Community Individuals with ICD-10 Disorders Across Age Groups: A Nationwide Population-Based Nested Case-Control Study in South Korea.

Na EJ, Lee H, Myung W, Fava M, Mischoulon D, Paik JW, Hong JP, Choi KW, Kim H, Jeon HJ.

Psychiatry Investig. 2019 Apr;16(4):314-324. doi: 10.30773/pi.2019.02.19. Epub 2019 Apr 24.


Childhood trauma history is linked to abnormal brain connectivity in major depression.

Yu M, Linn KA, Shinohara RT, Oathes DJ, Cook PA, Duprat R, Moore TM, Oquendo MA, Phillips ML, McInnis M, Fava M, Trivedi MH, McGrath P, Parsey R, Weissman MM, Sheline YI.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8582-8590. doi: 10.1073/pnas.1900801116. Epub 2019 Apr 8. Erratum in: Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13146.


Efficacy and Tolerability of Adjunctive Intravenous Sodium Nitroprusside Treatment for Outpatients With Schizophrenia: A Randomized Clinical Trial.

Brown HE, Freudenreich O, Fan X, Heard SO, Goff D, Petrides G, Harrington AL, Kane JM, Judge H, Hoeppner B, Fava M, Perlis RH.

JAMA Psychiatry. 2019 Jul 1;76(7):691-699. doi: 10.1001/jamapsychiatry.2019.0151.


Vortioxetine for attention deficit hyperactivity disorder in adults: A randomized, double-blind, placebo-controlled, proof-of-concept study.

Biederman J, Lindsten A, Sluth LB, Petersen ML, Ettrup A, Eriksen HF, Fava M.

J Psychopharmacol. 2019 Apr;33(4):511-521. doi: 10.1177/0269881119832538. Epub 2019 Mar 7.


Locally different proteome in aortas from patients with stenotic tricuspid and bicuspid aortic valves†.

Forte A, Yin X, Fava M, Bancone C, Cipollaro M, De Feo M, Mayr M, Jahangiri M, Della Corte A.

Eur J Cardiothorac Surg. 2019 Sep 1;56(3):458-469. doi: 10.1093/ejcts/ezz032.


A commentary on: statistical inference problems in sequential parallel comparison designs.

Schoenfeld DA, Doros G, Fava M.

J Biopharm Stat. 2019;29(6):1130-1133. doi: 10.1080/10543406.2019.1584207. Epub 2019 Feb 22.


Increased amygdala-visual cortex connectivity in youth with persecutory ideation.

DeCross SN, Farabaugh AH, Holmes AJ, Ward M, Boeke EA, Wolthusen RPF, Coombs G, Nyer M, Fava M, Buckner RL, Holt DJ.

Psychol Med. 2020 Jan;50(2):273-283. doi: 10.1017/S0033291718004221. Epub 2019 Feb 12.


Pretreatment Rostral Anterior Cingulate Cortex Connectivity With Salience Network Predicts Depression Recovery: Findings From the EMBARC Randomized Clinical Trial.

Whitton AE, Webb CA, Dillon DG, Kayser J, Rutherford A, Goer F, Fava M, McGrath P, Weissman M, Parsey R, Adams P, Trombello JM, Cooper C, Deldin P, Oquendo MA, McInnis MG, Carmody T, Bruder G, Trivedi MH, Pizzagalli DA.

Biol Psychiatry. 2019 May 15;85(10):872-880. doi: 10.1016/j.biopsych.2018.12.007. Epub 2018 Dec 19.


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