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Items: 10


Assessing the Utility of In Vitro Screening Tools for Predicting Bio-Performance of Oral Peptide Delivery.

Gadgil P, Alleyne C, Feng KI, Hu M, Gindy M, Buevich AV, Fauty S, Salituro G, Wen J, Li Y, Nofsinger R, Sawyer TK, Buist N.

Pharm Res. 2019 Aug 26;36(10):151. doi: 10.1007/s11095-019-2682-8.


Administration of Fenofibrate Markedly Elevates Fabp3 in Rat Liver and Plasma and Confounds Its Use as a Preclinical Biomarker of Cardiac and Muscle Toxicity.

Kochansky CJ, Lyman MJ, Fauty SE, Vlasakova K, D'mello AP.

Lipids. 2018 Oct;53(10):947-960. doi: 10.1002/lipd.12110.


Automated DBS microsampling, microscale automation and microflow LC-MS for therapeutic protein PK.

Zhang Q, Tomazela D, Vasicek LA, Spellman DS, Beaumont M, Shyong B, Kenny J, Fauty S, Fillgrove K, Harrelson J, Bateman KP.

Bioanalysis. 2016 Apr;8(7):649-59. doi: 10.4155/bio-2015-0006. Epub 2016 Mar 15.


Physicochemical properties, form, and formulation selection strategy for a biopharmaceutical classification system class II preclinical drug candidate.

Lohani S, Cooper H, Jin X, Nissley BP, Manser K, Rakes LH, Cummings JJ, Fauty SE, Bak A.

J Pharm Sci. 2014 Oct;103(10):3007-21. doi: 10.1002/jps.24088. Epub 2014 Jul 29.


siRNA-mediated knockdown of P450 oxidoreductase in rats: a tool to reduce metabolism by CYPs and increase exposure of high clearance compounds.

Burke RS, Somasuntharam I, Rearden P, Brown D, Deshmukh SV, DiPietro MA, DiMuzio J, Eisenhandler R, Fauty SE, Gibson C, Gindy ME, Hamilton KA, Knemeyer I, Koeplinger KA, Kwon HW, Lifsted TQ, Menzel K, Patel M, Pudvah N, Rudd DJ, Seitzer J, Strapps WR, Prueksaritanont T, Thompson CD, Hochman JH, Carr BA.

Pharm Res. 2014 Dec;31(12):3445-60. doi: 10.1007/s11095-014-1433-0. Epub 2014 Jul 1.


Combined use of crystalline sodium salt and polymeric precipitation inhibitors to improve pharmacokinetic profile of ibuprofen through supersaturation.

Terebetski JL, Cummings JJ, Fauty SE, Michniak-Kohn B.

AAPS PharmSciTech. 2014 Oct;15(5):1334-44. doi: 10.1208/s12249-014-0163-2. Epub 2014 Jun 12.


Quantitation of physiological and biochemical barriers to siRNA liver delivery via lipid nanoparticle platform.

Xu Y, Ou M, Keough E, Roberts J, Koeplinger K, Lyman M, Fauty S, Carlini E, Stern M, Zhang R, Yeh S, Mahan E, Wang Y, Slaughter D, Gindy M, Raab C, Thompson C, Hochman J.

Mol Pharm. 2014 May 5;11(5):1424-34. doi: 10.1021/mp400584h. Epub 2014 Apr 1.


The effect of the neonatal Fc receptor on human IgG biodistribution in mice.

Chen N, Wang W, Fauty S, Fang Y, Hamuro L, Hussain A, Prueksaritanont T.

MAbs. 2014 Mar-Apr;6(2):502-8. doi: 10.4161/mabs.27765. Epub 2014 Jan 9.


Lymphatic transport and catabolism of therapeutic proteins after subcutaneous administration to rats and dogs.

Wang W, Chen N, Shen X, Cunningham P, Fauty S, Michel K, Wang B, Hong X, Adreani C, Nunes CN, Johnson CV, Yin KC, Groff M, Zou Y, Liu L, Hamuro L, Prueksaritanont T.

Drug Metab Dispos. 2012 May;40(5):952-62. doi: 10.1124/dmd.111.043604. Epub 2012 Feb 10.


Using real-time quantitative TaqMan RT-PCR to evaluate the role of dexamethasone in gene regulation of rat P-glycoproteins mdr1a/1b and cytochrome P450 3A1/2.

Mei Q, Richards K, Strong-Basalyga K, Fauty SE, Taylor A, Yamazaki M, Prueksaritanont T, Lin JH, Hochman J.

J Pharm Sci. 2004 Oct;93(10):2488-96.


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