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Smooth muscle of the male pelvic floor: An anatomic study.

Nyangoh Timoh K, Deffon J, Moszkowicz D, Lebacle C, Creze M, Martinovic J, Zaitouna M, Diallo D, Lavoue V, Fautrel A, Benoit G, Bessede T.

Clin Anat. 2019 Nov 19. doi: 10.1002/ca.23515. [Epub ahead of print]


Serum CD95L Level Correlates with Tumor Immune Infiltration and Is a Positive Prognostic Marker for Advanced High-Grade Serous Ovarian Cancer.

De La Motte Rouge T, Corné J, Cauchois A, Le Boulch M, Poupon C, Henno S, Rioux-Leclercq N, Le Pabic E, Laviolle B, Catros V, Levêque J, Fautrel A, Le Gallo M, Legembre P, Lavoué V.

Mol Cancer Res. 2019 Dec;17(12):2537-2548. doi: 10.1158/1541-7786.MCR-19-0449. Epub 2019 Sep 19.


Influence of inflammasome pathway activation in macrophages on the matrix metalloproteinase expression of human hepatic stellate cells.

Robert S, Gicquel T, Bodin A, Fautrel A, Barreto E, Victoni T, Lagente V, Boichot E.

Int Immunopharmacol. 2019 Jul;72:12-20. doi: 10.1016/j.intimp.2019.03.060. Epub 2019 Apr 4.


Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.

Billot K, Coquil C, Villiers B, Josselin-Foll B, Desban N, Delehouzé C, Oumata N, Le Meur Y, Boletta A, Weimbs T, Grosch M, Witzgall R, Saunier S, Fischer E, Pontoglio M, Fautrel A, Mrug M, Wallace D, Tran PV, Trudel M, Bukanov N, Ibraghimov-Beskrovnaya O, Meijer L.

Am J Physiol Renal Physiol. 2018 Jul 1;315(1):F57-F73. doi: 10.1152/ajprenal.00489.2017. Epub 2018 Mar 14.


A novel transforming growth factor beta-induced long noncoding RNA promotes an inflammatory microenvironment in human intrahepatic cholangiocarcinoma.

Merdrignac A, Angenard G, Allain C, Petitjean K, Bergeat D, Bellaud P, Fautrel A, Turlin B, Clément B, Dooley S, Sulpice L, Boudjema K, Coulouarn C.

Hepatol Commun. 2018 Jan 30;2(3):254-269. doi: 10.1002/hep4.1142. eCollection 2018 Mar.


Propolis reversed cigarette smoke-induced emphysema through macrophage alternative activation independent of Nrf2.

Barroso MV, Cattani-Cavalieri I, de Brito-Gitirana L, Fautrel A, Lagente V, Schmidt M, Porto LC, Romana-Souza B, Valença SS, Lanzetti M.

Bioorg Med Chem. 2017 Oct 15;25(20):5557-5568. doi: 10.1016/j.bmc.2017.08.026. Epub 2017 Aug 19.


Slice correspondence estimation using SURF descriptors and context-based search for prostate whole-mount histology MRI registration.

Guzman L, Commandeur F, Acosta O, Simon A, Fautrel A, Rioux-Leclercq N, Romero E, Mathieu R, de Crevoisier R.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:1163-1166. doi: 10.1109/EMBC.2016.7590911.


Mid-infrared fibre evanescent wave spectroscopy of serum allows fingerprinting of the hepatic metabolic status in mice.

Le Corvec M, Allain C, Lardjane S, Cavey T, Turlin B, Fautrel A, Begriche K, Monbet V, Fromenty B, Leroyer P, Guggenbuhl P, Ropert M, Sire O, Loréal O.

Analyst. 2016 Oct 24;141(22):6259-6269.


CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice.

Poissonnier A, Sanséau D, Le Gallo M, Malleter M, Levoin N, Viel R, Morere L, Penna A, Blanco P, Dupuy A, Poizeau F, Fautrel A, Seneschal J, Jouan F, Ritz J, Forcade E, Rioux N, Contin-Bordes C, Ducret T, Vacher AM, Barrow PA, Flynn RJ, Vacher P, Legembre P.

Immunity. 2016 Jul 19;45(1):209-23. doi: 10.1016/j.immuni.2016.06.028.


Impact of stroma LOXL2 overexpression on the prognosis of intrahepatic cholangiocarcinoma.

Bergeat D, Fautrel A, Turlin B, Merdrignac A, Rayar M, Boudjema K, Coulouarn C, Sulpice L.

J Surg Res. 2016 Jun 15;203(2):441-50. doi: 10.1016/j.jss.2016.03.044. Epub 2016 Mar 26.


Gene expression profiling of the tumor microenvironment in human intrahepatic cholangiocarcinoma.

Sulpice L, Desille M, Turlin B, Fautrel A, Boudjema K, Clément B, Coulouarn C.

Genom Data. 2016 Jan 15;7:229-32. doi: 10.1016/j.gdata.2016.01.012. eCollection 2016 Mar.


Prostate whole-mount histology reconstruction and registration to MRI for correlating in-vivo observations with biological findings.

Commandeur F, Acosta O, Simon A, Mathieu R, Fautrel A, Gnep K, Haigron P, de Crevoisier R.

Conf Proc IEEE Eng Med Biol Soc. 2015;2015:2399-402. doi: 10.1109/EMBC.2015.7318877.


Transcriptomic Analysis of Trout Gill Ionocytes in Fresh Water and Sea Water Using Laser Capture Microdissection Combined with Microarray Analysis.

Leguen I, Le Cam A, Montfort J, Peron S, Fautrel A.

PLoS One. 2015 Oct 6;10(10):e0139938. doi: 10.1371/journal.pone.0139938. eCollection 2015.


Excessive dietary linoleic acid induces proinflammatory markers in rats.

Marchix J, Choque B, Kouba M, Fautrel A, Catheline D, Legrand P.

J Nutr Biochem. 2015 Dec;26(12):1434-41. doi: 10.1016/j.jnutbio.2015.07.010. Epub 2015 Jul 30.


Prognostic and predictive values of oncogenic BRAF, NRAS, c-KIT and MITF in cutaneous and mucous melanoma.

Pracht M, Mogha A, Lespagnol A, Fautrel A, Mouchet N, Le Gall F, Paumier V, Lefeuvre-Plesse C, Rioux-Leclerc N, Mosser J, Oger E, Adamski H, Galibert MD, Lesimple T.

J Eur Acad Dermatol Venereol. 2015 Aug;29(8):1530-8. doi: 10.1111/jdv.12910. Epub 2015 Jan 26.


A spontaneous KRT16 mutation in a dog breed: a model for human focal non-epidermolytic palmoplantar keratoderma (FNEPPK).

Plassais J, Guaguère E, Lagoutte L, Guillory AS, de Citres CD, Degorce-Rubiales F, Delverdier M, Vaysse A, Quignon P, Bleuart C, Hitte C, Fautrel A, Kaerle C, Bellaud P, Bensignor E, Queney G, Bourrat E, Thomas A, André C.

J Invest Dermatol. 2015 Apr;135(4):1187-1190. doi: 10.1038/jid.2014.526. Epub 2014 Dec 18. No abstract available.


Comparative transcriptional profiling of human Merkel cells and Merkel cell carcinoma.

Mouchet N, Coquart N, Lebonvallet N, Le Gall-Ianotto C, Mogha A, Fautrel A, Boulais N, Dréno B, Martin L, Hu W, Galibert MD, Misery L.

Exp Dermatol. 2014 Dec;23(12):928-30. doi: 10.1111/exd.12546. Epub 2014 Nov 11.


Overexpression of MLN51 triggers P-body disassembly and formation of a new type of RNA granules.

Cougot N, Daguenet E, Baguet A, Cavalier A, Thomas D, Bellaud P, Fautrel A, Godey F, Bertrand E, Tomasetto C, Gillet R.

J Cell Sci. 2014 Nov 1;127(Pt 21):4692-701. doi: 10.1242/jcs.154500. Epub 2014 Sep 9.


Involvement of purinergic receptors and NOD-like receptor-family protein 3-inflammasome pathway in the adenosine triphosphate-induced cytokine release from macrophages.

Gicquel T, Victoni T, Fautrel A, Robert S, Gleonnec F, Guezingar M, Couillin I, Catros V, Boichot E, Lagente V.

Clin Exp Pharmacol Physiol. 2014 Apr;41(4):279-86. doi: 10.1111/1440-1681.12214.


Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma.

Sulpice L, Rayar M, Desille M, Turlin B, Fautrel A, Boucher E, Llamas-Gutierrez F, Meunier B, Boudjema K, Clément B, Coulouarn C.

Hepatology. 2013 Dec;58(6):1992-2000. doi: 10.1002/hep.26577. Epub 2013 Oct 17.


Gene expression profiling of the hyperplastic growth zones of the late trout embryo myotome using laser capture microdissection and microarray analysis.

Rescan PY, Montfort J, Fautrel A, Rallière C, Lebret V.

BMC Genomics. 2013 Mar 14;14:173. doi: 10.1186/1471-2164-14-173.


The gene transfection properties of a lipophosphoramidate derivative with two phytanyl chains.

Lindberg MF, Carmoy N, Le Gall T, Fraix A, Berchel M, Lorilleux C, Couthon-Gourvès H, Bellaud P, Fautrel A, Jaffrès PA, Lehn P, Montier T.

Biomaterials. 2012 Sep;33(26):6240-53. doi: 10.1016/j.biomaterials.2012.05.014. Epub 2012 Jun 5.


Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liver.

Knockaert L, Berson A, Ribault C, Prost PE, Fautrel A, Pajaud J, Lepage S, Lucas-Clerc C, Bégué JM, Fromenty B, Robin MA.

Lab Invest. 2012 Mar;92(3):396-410. doi: 10.1038/labinvest.2011.193. Epub 2011 Dec 12.


Identification of early target genes of aflatoxin B1 in human hepatocytes, inter-individual variability and comparison with other genotoxic compounds.

Josse R, Dumont J, Fautrel A, Robin MA, Guillouzo A.

Toxicol Appl Pharmacol. 2012 Jan 15;258(2):176-87. doi: 10.1016/j.taap.2011.10.019. Epub 2011 Nov 4.


Overexpression of active Aurora-C kinase results in cell transformation and tumour formation.

Khan J, Ezan F, Crémet JY, Fautrel A, Gilot D, Lambert M, Benaud C, Troadec MB, Prigent C.

PLoS One. 2011;6(10):e26512. doi: 10.1371/journal.pone.0026512. Epub 2011 Oct 27.


IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis.

Gasse P, Riteau N, Vacher R, Michel ML, Fautrel A, di Padova F, Fick L, Charron S, Lagente V, Eberl G, Le Bert M, Quesniaux VF, Huaux F, Leite-de-Moraes M, Ryffel B, Couillin I.

PLoS One. 2011;6(8):e23185. doi: 10.1371/journal.pone.0023185. Epub 2011 Aug 16.


Pentoxifylline aggravates fatty liver in obese and diabetic ob/ob mice by increasing intestinal glucose absorption and activating hepatic lipogenesis.

Massart J, Robin MA, Noury F, Fautrel A, Lettéron P, Bado A, Eliat PA, Fromenty B.

Br J Pharmacol. 2012 Mar;165(5):1361-74. doi: 10.1111/j.1476-5381.2011.01580.x.


Merkel cell polyomavirus small T antigen mRNA level is increased following in vivo UV-radiation.

Mogha A, Fautrel A, Mouchet N, Guo N, Corre S, Adamski H, Watier E, Misery L, Galibert MD.

PLoS One. 2010 Jul 2;5(7):e11423. doi: 10.1371/journal.pone.0011423.


Brassica orthologs from BANYULS belong to a small multigene family, which is involved in procyanidin accumulation in the seed.

Auger B, Baron C, Lucas MO, Vautrin S, Bergès H, Chalhoub B, Fautrel A, Renard M, Nesi N.

Planta. 2009 Nov;230(6):1167-83. doi: 10.1007/s00425-009-1017-0. Epub 2009 Sep 17.


Chronic ethanol consumption lessens the gain of body weight, liver triglycerides, and diabetes in obese ob/ob mice.

Fromenty B, Vadrot N, Massart J, Turlin B, Barri-Ova N, Lettéron P, Fautrel A, Robin MA.

J Pharmacol Exp Ther. 2009 Oct;331(1):23-34. doi: 10.1124/jpet.109.155168. Epub 2009 Jul 8.


Ectopic germinal centers are rare in Sjogren's syndrome salivary glands and do not exclude autoreactive B cells.

Le Pottier L, Devauchelle V, Fautrel A, Daridon C, Saraux A, Youinou P, Pers JO.

J Immunol. 2009 Mar 15;182(6):3540-7. doi: 10.4049/jimmunol.0803588.


RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo.

Bessard A, Frémin C, Ezan F, Fautrel A, Gailhouste L, Baffet G.

Oncogene. 2008 Sep 11;27(40):5315-25. doi: 10.1038/onc.2008.163. Epub 2008 Jun 2.


Transcripts of ceruloplasmin but not hepcidin, both major iron metabolism genes, exhibit a decreasing pattern along the portocentral axis of mouse liver.

Troadec MB, Fautrel A, Drénou B, Leroyer P, Camberlein E, Turlin B, Guillouzo A, Brissot P, Loréal O.

Biochim Biophys Acta. 2008 Apr;1782(4):239-49. doi: 10.1016/j.bbadis.2007.12.009. Epub 2008 Jan 3.


GATA-1 is essential in EGF-mediated induction of nucleotide excision repair activity and ERCC1 expression through ERK2 in human hepatoma cells.

Andrieux LO, Fautrel A, Bessard A, Guillouzo A, Baffet G, Langouët S.

Cancer Res. 2007 Mar 1;67(5):2114-23.


Overexpression of the two nucleotide excision repair genes ERCC1 and XPC in human hepatocellular carcinoma.

Fautrel A, Andrieux L, Musso O, Boudjema K, Guillouzo A, Langouët S.

J Hepatol. 2005 Aug;43(2):288-93. Epub 2005 Apr 25.


Behavioral and neurochemical effects induced by subchronic combined exposure to toluene at 40 ppm and noise at 80 dB-A in rats.

Berenguer P, Soulage C, Fautrel A, Péquignot JM, Abraini JH.

Physiol Behav. 2004 May;81(3):527-34.


Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes.

Andrieux L, Langouët S, Fautrel A, Ezan F, Krauser JA, Savouret JF, Guengerich FP, Baffet G, Guillouzo A.

Mol Pharmacol. 2004 Apr;65(4):934-43.


Expression of cytochromes P450 3A in mouse lung: effects of dexamethasone and pregnenolone 16alpha-carbonitrile.

Haag M, Fautrel A, Guillouzo A, Frossard N, Pons F.

Arch Toxicol. 2003 Mar;77(3):145-9. Epub 2002 Dec 4.


Inhibition of cytochrome P450 2E1 by propofol in human and porcine liver microsomes.

Lejus C, Fautrel A, Mallédant Y, Guillouzo A.

Biochem Pharmacol. 2002 Oct 1;64(7):1151-6.


Investigations on the effects of oltipraz on the nucleotide excision repair in the liver.

Sparfel L, Langouët S, Fautrel A, Salles B, Guillouzo A.

Biochem Pharmacol. 2002 Feb 15;63(4):745-9.


Determination of nucleotide excision repair capacity of liver cells in vivo and in vitro by a cell-free assay.

Sparfel L, Langouët S, Fautrel A, Salles B, Guillouzo A.

Adv Exp Med Biol. 2001;500:625-8. No abstract available.


Phenobarbital induction of aldehyde dehydrogenase type 2 mRNA in mouse liver: a candidate region on chromosome 7 for a putative regulatory gene.

Marc N, Fautrel A, Damon M, Guillouzo A, Corcos L.

Biochem Genet. 2000 Oct;38(9-10):297-307.


Regulation of phenobarbital induction of the cytochrome P450 2b9/10 genes in primary mouse hepatocyte culture. Involvement of calcium- and cAMP-dependent pathways.

Marc N, Galisteo M, Lagadic-Gossmann D, Fautrel A, Joannard F, Guillouzo A, Corcos L.

Eur J Biochem. 2000 Feb;267(4):963-70.


Involvement of cyclic nucleotide- and calcium-regulated pathways in phenobarbital-induced cytochrome P-450 3A expression in mouse primary hepatocytes.

Galisteo M, Marc N, Fautrel A, Guillouzo A, Corcos L, Lagadic-Gossmann D.

J Pharmacol Exp Ther. 1999 Sep;290(3):1270-7.


A multi-laboratory evaluation of cryopreserved monkey hepatocyte functions for use in pharmaco-toxicology.

de Sousa G, Nicolas F, Placidi M, Rahmani R, Benicourt M, Vannier B, Lorenzon G, Mertens K, Coecke S, Callaerts A, Rogiers V, Khan S, Roberts P, Skett P, Fautrel A, Chesne C, Guillouzo A.

Chem Biol Interact. 1999 Jun 1;121(1):77-97.


Survival and function of isolated hepatocytes after cryopreservation.

Guillouzo A, Rialland L, Fautrel A, Guyomard C.

Chem Biol Interact. 1999 Jun 1;121(1):7-16. Review.


Isolation of a cyp2b10-like cDNA and of a clone derived from a cyp2b10-like pseudogene.

Marc N, Damon M, Fautrel A, Guillouzo A, Corcos L.

Biochem Biophys Res Commun. 1999 Apr 29;258(1):11-6.


Long-term maintenance of drug-metabolizing enzyme activities in rat hepatocytes after cryopreservation.

Fautrel A, Joly B, Guyomard C, Guillouzo A.

Toxicol Appl Pharmacol. 1997 Nov;147(1):110-4.


Regulation of the major detoxication functions by phenobarbital and 3-methylcholanthrene in co-cultures of rat hepatocytes and liver epithelial cells.

Lerche C, Fautrel A, Shaw PM, Glaise D, Ballet F, Guillouzo A, Corcos L.

Eur J Biochem. 1997 Feb 15;244(1):98-106.

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