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Items: 7


Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized Immunotherapy.

Maby P, Tougeron D, Hamieh M, Mlecnik B, Kora H, Bindea G, Angell HK, Fredriksen T, Elie N, Fauquembergue E, Drouet A, Leprince J, Benichou J, Mauillon J, Le Pessot F, Sesboüé R, Tuech JJ, Sabourin JC, Michel P, Frébourg T, Galon J, Latouche JB.

Cancer Res. 2015 Sep 1;75(17):3446-55. doi: 10.1158/0008-5472.CAN-14-3051. Epub 2015 Jun 9.


Direct Toll-Like Receptor 8 signaling increases the functional avidity of human CD8+ T lymphocytes generated for adoptive T cell therapy strategies.

Chatillon JF, Hamieh M, Bayeux F, Abasq C, Fauquembergue E, Drouet A, Guisier F, Latouche JB, Musette P.

Immun Inflamm Dis. 2015 Mar;3(1):1-13. doi: 10.1002/iid3.43. Epub 2015 Feb 19.


[Immunotherapy for colorectal cancer].

Tougeron D, Fauquembergue É, Latouche JB.

Bull Cancer. 2013 Sep;100(9):871-85. doi: 10.1684/bdc.2013.1800. Review. French.


Regulatory T lymphocytes are associated with less aggressive histologic features in microsatellite-unstable colorectal cancers.

Tougeron D, Maby P, Elie N, Fauquembergue E, Le Pessot F, Cornic M, Sabourin JC, Michel P, Frébourg T, Latouche JB.

PLoS One. 2013 Apr 15;8(4):e61001. doi: 10.1371/journal.pone.0061001. Print 2013.


[Immune response and colorectal cancer].

Tougeron D, Fauquembergue E, Latouche JB.

Bull Cancer. 2013 Mar;100(3):283-94. doi: 10.1684/bdc.2013.1716. Review. French.


HLA-A*0201-restricted CEA-derived peptide CAP1 is not a suitable target for T-cell-based immunotherapy.

Fauquembergue E, Toutirais O, Tougeron D, Drouet A, Le Gallo M, Desille M, Cabillic F, de La Pintière CT, Iero M, Rivoltini L, Baert-Desurmont S, Leprince J, Vaudry H, Sesboué R, Frébourg T, Latouche JB, Catros V.

J Immunother. 2010 May;33(4):402-13. doi: 10.1097/CJI.0b013e3181d366da.


Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations.

Tougeron D, Fauquembergue E, Rouquette A, Le Pessot F, Sesboüé R, Laurent M, Berthet P, Mauillon J, Di Fiore F, Sabourin JC, Michel P, Tosi M, Frébourg T, Latouche JB.

Mod Pathol. 2009 Sep;22(9):1186-95. doi: 10.1038/modpathol.2009.80. Epub 2009 Jun 5.

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