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Items: 1 to 50 of 307

1.

The Role of Microglia and Astrocytes in Huntington's Disease.

Palpagama TH, Waldvogel HJ, Faull RLM, Kwakowsky A.

Front Mol Neurosci. 2019 Oct 25;12:258. doi: 10.3389/fnmol.2019.00258. eCollection 2019.

2.

Altered microglia and neurovasculature in the Alzheimer's disease cerebellum.

Singh-Bains MK, Linke V, Austria MDR, Tan AYS, Scotter EL, Mehrabi NF, Faull RLM, Dragunow M.

Neurobiol Dis. 2019 Dec;132:104589. doi: 10.1016/j.nbd.2019.104589. Epub 2019 Aug 24.

PMID:
31454549
3.

GABAA Receptors Are Well Preserved in the Hippocampus of Aged Mice.

Palpagama TH, Sagniez M, Kim S, Waldvogel HJ, Faull RL, Kwakowsky A.

eNeuro. 2019 Aug 14;6(4). pii: ENEURO.0496-18.2019. doi: 10.1523/ENEURO.0496-18.2019. Print 2019 Jul/Aug.

4.

Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington's Disease.

Patassini S, Begley P, Xu J, Church SJ, Kureishy N, Reid SJ, Waldvogel HJ, Faull RLM, Snell RG, Unwin RD, Cooper GJS.

Metabolites. 2019 Jun 11;9(6). pii: E113. doi: 10.3390/metabo9060113.

5.

Vascular Dysfunction in Alzheimer's Disease: A Prelude to the Pathological Process or a Consequence of It?

Govindpani K, McNamara LG, Smith NR, Vinnakota C, Waldvogel HJ, Faull RL, Kwakowsky A.

J Clin Med. 2019 May 10;8(5). pii: E651. doi: 10.3390/jcm8050651. Review.

6.

Variable colocalisation of GABAA receptor subunits and glycine receptors on neurons in the human hypoglossal nucleus.

Waldvogel HJ, Biggins FM, Singh A, Arasaratnam CJ, Faull RLM.

J Chem Neuroanat. 2019 Apr;97:99-111. doi: 10.1016/j.jchemneu.2019.02.005. Epub 2019 Feb 27.

PMID:
30825508
7.

Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.

Dominy SS, Lynch C, Ermini F, Benedyk M, Marczyk A, Konradi A, Nguyen M, Haditsch U, Raha D, Griffin C, Holsinger LJ, Arastu-Kapur S, Kaba S, Lee A, Ryder MI, Potempa B, Mydel P, Hellvard A, Adamowicz K, Hasturk H, Walker GD, Reynolds EC, Faull RLM, Curtis MA, Dragunow M, Potempa J.

Sci Adv. 2019 Jan 23;5(1):eaau3333. doi: 10.1126/sciadv.aau3333. eCollection 2019 Jan.

8.

Regional protein expression in human Alzheimer's brain correlates with disease severity.

Xu J, Patassini S, Rustogi N, Riba-Garcia I, Hale BD, Phillips AM, Waldvogel H, Haines R, Bradbury P, Stevens A, Faull RLM, Dowsey AW, Cooper GJS, Unwin RD.

Commun Biol. 2019 Feb 4;2:43. doi: 10.1038/s42003-018-0254-9. eCollection 2019.

9.

Chemical neuroanatomy of the substantia nigra in the ovine brain.

Murray SJ, Black BL, Reid SJ, Rudiger SR, Simon Bawden C, Snell RG, Waldvogel HJ, Faull RLM.

J Chem Neuroanat. 2019 Apr;97:43-56. doi: 10.1016/j.jchemneu.2019.01.007. Epub 2019 Jan 18.

PMID:
30664938
10.

Sex- and age-related changes in GABA signaling components in the human cortex.

Pandya M, Palpagama TH, Turner C, Waldvogel HJ, Faull RL, Kwakowsky A.

Biol Sex Differ. 2019 Jan 14;10(1):5. doi: 10.1186/s13293-018-0214-6.

11.

Cerebellar degeneration correlates with motor symptoms in Huntington disease.

Singh-Bains MK, Mehrabi NF, Sehji T, Austria MDR, Tan AYS, Tippett LJ, Dragunow M, Waldvogel HJ, Faull RLM.

Ann Neurol. 2019 Mar;85(3):396-405. doi: 10.1002/ana.25413. Epub 2019 Feb 4.

12.

Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease.

Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Müller F, Scherzer CR.

Nat Neurosci. 2019 Jan;22(1):144-147. doi: 10.1038/s41593-018-0277-z.

PMID:
30482917
13.

Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease.

Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Müller F, Scherzer CR.

Nat Neurosci. 2018 Oct;21(10):1482-1492. doi: 10.1038/s41593-018-0223-0. Epub 2018 Sep 17. Erratum in: Nat Neurosci. 2019 Jan;22(1):144-147.

14.

PU.1 regulates Alzheimer's disease-associated genes in primary human microglia.

Rustenhoven J, Smith AM, Smyth LC, Jansson D, Scotter EL, Swanson MEV, Aalderink M, Coppieters N, Narayan P, Handley R, Overall C, Park TIH, Schweder P, Heppner P, Curtis MA, Faull RLM, Dragunow M.

Mol Neurodegener. 2018 Aug 20;13(1):44. doi: 10.1186/s13024-018-0277-1.

15.

Gamma-aminobutyric acid A receptors in Alzheimer's disease: highly localized remodeling of a complex and diverse signaling pathway.

Kwakowsky A, Calvo-Flores Guzmán B, Govindpani K, Waldvogel HJ, Faull RL.

Neural Regen Res. 2018 Aug;13(8):1362-1363. doi: 10.4103/1673-5374.235240. No abstract available.

16.

Markers for human brain pericytes and smooth muscle cells.

Smyth LCD, Rustenhoven J, Scotter EL, Schweder P, Faull RLM, Park TIH, Dragunow M.

J Chem Neuroanat. 2018 Oct;92:48-60. doi: 10.1016/j.jchemneu.2018.06.001. Epub 2018 Jun 7.

PMID:
29885791
17.

Stereological Methods to Quantify Cell Loss in the Huntington's Disease Human Brain.

Mehrabi NF, Singh-Bains MK, Waldvogel HJ, Faull RLM.

Methods Mol Biol. 2018;1780:1-16. doi: 10.1007/978-1-4939-7825-0_1.

PMID:
29856011
18.

Subventricular zone lipidomic architecture loss in Huntington's disease.

Hunter M, Demarais NJ, Faull RLM, Grey AC, Curtis MA.

J Neurochem. 2018 Sep;146(5):613-630. doi: 10.1111/jnc.14468. Epub 2018 Aug 8.

19.

Unique and shared inflammatory profiles of human brain endothelia and pericytes.

Smyth LCD, Rustenhoven J, Park TI, Schweder P, Jansson D, Heppner PA, O'Carroll SJ, Mee EW, Faull RLM, Curtis M, Dragunow M.

J Neuroinflammation. 2018 May 11;15(1):138. doi: 10.1186/s12974-018-1167-8.

20.

Differential Fatty Acid-Binding Protein Expression in Persistent Radial Glia in the Human and Sheep Subventricular Zone.

Dieriks BV, Dean JM, Aronica E, Waldvogel HJ, Faull RLM, Curtis MA.

Dev Neurosci. 2018;40(2):145-161. doi: 10.1159/000487633. Epub 2018 Apr 20.

PMID:
29680832
21.

The GABAergic system as a therapeutic target for Alzheimer's disease.

Calvo-Flores Guzmán B, Vinnakota C, Govindpani K, Waldvogel HJ, Faull RLM, Kwakowsky A.

J Neurochem. 2018 Sep;146(6):649-669. doi: 10.1111/jnc.14345. Epub 2018 Aug 1. Review.

22.

GABAA receptor subunit expression changes in the human Alzheimer's disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus.

Kwakowsky A, Calvo-Flores Guzmán B, Pandya M, Turner C, Waldvogel HJ, Faull RL.

J Neurochem. 2018 Jun;145(5):374-392. doi: 10.1111/jnc.14325.

23.

Modelling physiological and pathological conditions to study pericyte biology in brain function and dysfunction.

Rustenhoven J, Smyth LC, Jansson D, Schweder P, Aalderink M, Scotter EL, Mee EW, Faull RLM, Park TI, Dragunow M.

BMC Neurosci. 2018 Feb 22;19(1):6. doi: 10.1186/s12868-018-0405-4.

24.

Neurochemical Characterization of PSA-NCAM+ Cells in the Human Brain and Phenotypic Quantification in Alzheimer's Disease Entorhinal Cortex.

Murray HC, Swanson MEV, Dieriks BV, Turner C, Faull RLM, Curtis MA.

Neuroscience. 2018 Feb 21;372:289-303. doi: 10.1016/j.neuroscience.2017.12.019.

PMID:
29429526
25.

Layer-specific lipid signatures in the human subventricular zone demonstrated by imaging mass spectrometry.

Hunter M, Demarais NJ, Faull RLM, Grey AC, Curtis MA.

Sci Rep. 2018 Feb 7;8(1):2551. doi: 10.1038/s41598-018-20793-4.

26.

Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.

Handley RR, Reid SJ, Brauning R, Maclean P, Mears ER, Fourie I, Patassini S, Cooper GJS, Rudiger SR, McLaughlan CJ, Verma PJ, Gusella JF, MacDonald ME, Waldvogel HJ, Bawden CS, Faull RLM, Snell RG.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11293-E11302. doi: 10.1073/pnas.1711243115. Epub 2017 Dec 11.

27.

GABAA and GABAB receptor subunit localization on neurochemically identified neurons of the human subthalamic nucleus.

Wu XH, Song JJ, Faull RLM, Waldvogel HJ.

J Comp Neurol. 2018 Apr 1;526(5):803-823. doi: 10.1002/cne.24368. Epub 2017 Dec 22.

PMID:
29218727
28.

A ventral glomerular deficit in Parkinson's disease revealed by whole olfactory bulb reconstruction.

Zapiec B, Dieriks BV, Tan S, Faull RLM, Mombaerts P, Curtis MA.

Brain. 2017 Oct 1;140(10):2722-2736. doi: 10.1093/brain/awx208.

29.

Metal concentrations and distributions in the human olfactory bulb in Parkinson's disease.

Gardner B, Dieriks BV, Cameron S, Mendis LHS, Turner C, Faull RLM, Curtis MA.

Sci Rep. 2017 Sep 5;7(1):10454. doi: 10.1038/s41598-017-10659-6.

30.

Towards a Better Understanding of GABAergic Remodeling in Alzheimer's Disease.

Govindpani K, Calvo-Flores Guzmán B, Vinnakota C, Waldvogel HJ, Faull RL, Kwakowsky A.

Int J Mol Sci. 2017 Aug 21;18(8). pii: E1813. doi: 10.3390/ijms18081813. Review.

31.

Alzheimer's disease markers in the aged sheep (Ovis aries).

Reid SJ, Mckean NE, Henty K, Portelius E, Blennow K, Rudiger SR, Bawden CS, Handley RR, Verma PJ, Faull RLM, Waldvogel HJ, Zetterberg H, Snell RG.

Neurobiol Aging. 2017 Oct;58:112-119. doi: 10.1016/j.neurobiolaging.2017.06.020. Epub 2017 Jun 24.

PMID:
28728117
32.

The Complexity of Clinical Huntington's Disease: Developments in Molecular Genetics, Neuropathology and Neuroimaging Biomarkers.

Tippett LJ, Waldvogel HJ, Snell RG, Vonsattel JP, Young AB, Faull RLM.

Adv Neurobiol. 2017;15:129-161. doi: 10.1007/978-3-319-57193-5_5. Review.

PMID:
28674980
33.

Evidence for widespread, severe brain copper deficiency in Alzheimer's dementia.

Xu J, Church SJ, Patassini S, Begley P, Waldvogel HJ, Curtis MA, Faull RLM, Unwin RD, Cooper GJS.

Metallomics. 2017 Aug 16;9(8):1106-1119. doi: 10.1039/c7mt00074j.

PMID:
28654115
34.

Effect of post-mortem delay on N-terminal huntingtin protein fragments in human control and Huntington disease brain lysates.

Schut MH, Patassini S, Kim EH, Bullock J, Waldvogel HJ, Faull RLM, Pepers BA, den Dunnen JT, van Ommen GB, van Roon-Mom WMC.

PLoS One. 2017 Jun 1;12(6):e0178556. doi: 10.1371/journal.pone.0178556. eCollection 2017.

35.

The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients.

Neueder A, Landles C, Ghosh R, Howland D, Myers RH, Faull RLM, Tabrizi SJ, Bates GP.

Sci Rep. 2017 May 2;7(1):1307. doi: 10.1038/s41598-017-01510-z.

36.

The immunohistochemical distribution of the GABAA receptor α1, α2, α3, β2/3 and γ2 subunits in the human thalamus.

Waldvogel HJ, Munkle M, van Roon-Mom W, Mohler H, Faull RLM.

J Chem Neuroanat. 2017 Jul;82:39-55. doi: 10.1016/j.jchemneu.2017.04.006. Epub 2017 Apr 23.

PMID:
28445782
37.

Impaired expression of GABA transporters in the human Alzheimer's disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus.

Fuhrer TE, Palpagama TH, Waldvogel HJ, Synek BJL, Turner C, Faull RL, Kwakowsky A.

Neuroscience. 2017 May 20;351:108-118. doi: 10.1016/j.neuroscience.2017.03.041. Epub 2017 Apr 4.

PMID:
28385633
38.

Insulin promotes cell migration by regulating PSA-NCAM.

Monzo HJ, Coppieters N, Park TIH, Dieriks BV, Faull RLM, Dragunow M, Curtis MA.

Exp Cell Res. 2017 Jun 1;355(1):26-39. doi: 10.1016/j.yexcr.2017.03.029. Epub 2017 Mar 21.

PMID:
28341445
39.

α-synuclein transfer through tunneling nanotubes occurs in SH-SY5Y cells and primary brain pericytes from Parkinson's disease patients.

Dieriks BV, Park TI, Fourie C, Faull RL, Dragunow M, Curtis MA.

Sci Rep. 2017 Feb 23;7:42984. doi: 10.1038/srep42984.

40.

Effect of Estradiol on Neurotrophin Receptors in Basal Forebrain Cholinergic Neurons: Relevance for Alzheimer's Disease.

Kwakowsky A, Milne MR, Waldvogel HJ, Faull RL.

Int J Mol Sci. 2016 Dec 17;17(12). pii: E2122. doi: 10.3390/ijms17122122. Review.

41.
42.

Symptom heterogeneity in Huntington's disease correlates with neuronal degeneration in the cerebral cortex.

Mehrabi NF, Waldvogel HJ, Tippett LJ, Hogg VM, Synek BJ, Faull RL.

Neurobiol Dis. 2016 Dec;96:67-74. doi: 10.1016/j.nbd.2016.08.015. Epub 2016 Aug 25.

PMID:
27569581
43.

Comparison of Huntington's disease CAG Repeat Length Stability in Human Motor Cortex and Cingulate Gyrus.

Geraerts FC, Snell RG, Faull RL, Williams L, Jacobsen JC, Reid SJ.

J Huntingtons Dis. 2016 Oct 1;5(3):297-301.

PMID:
27716680
44.

Interferon-γ blocks signalling through PDGFRβ in human brain pericytes.

Jansson D, Scotter EL, Rustenhoven J, Coppieters N, Smyth LC, Oldfield RL, Bergin PS, Mee EW, Graham ES, Faull RL, Dragunow M.

J Neuroinflammation. 2016 Sep 21;13(1):249.

45.

The role of the human globus pallidus in Huntington's disease.

Singh-Bains MK, Waldvogel HJ, Faull RL.

Brain Pathol. 2016 Nov;26(6):741-751. doi: 10.1111/bpa.12429. Review.

PMID:
27529459
46.

C9ORF72 and UBQLN2 mutations are causes of amyotrophic lateral sclerosis in New Zealand: a genetic and pathologic study using banked human brain tissue.

Scotter EL, Smyth L, Bailey JAWT, Wong CH, de Majo M, Vance CA, Synek BJ, Turner C, Pereira J, Charleston A, Waldvogel HJ, Curtis MA, Dragunow M, Shaw CE, Smith BN, Faull RLM.

Neurobiol Aging. 2017 Jan;49:214.e1-214.e5. doi: 10.1016/j.neurobiolaging.2016.06.019. Epub 2016 Jul 5.

PMID:
27480424
47.

Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels.

Horvath S, Langfelder P, Kwak S, Aaronson J, Rosinski J, Vogt TF, Eszes M, Faull RL, Curtis MA, Waldvogel HJ, Choi OW, Tung S, Vinters HV, Coppola G, Yang XW.

Aging (Albany NY). 2016 Jul;8(7):1485-512. doi: 10.18632/aging.101005.

48.

Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease.

Lin L, Park JW, Ramachandran S, Zhang Y, Tseng YT, Shen S, Waldvogel HJ, Curtis MA, Faull RL, Troncoso JC, Pletnikova O, Ross CA, Davidson BL, Xing Y.

Hum Mol Genet. 2016 Aug 15;25(16):3454-3466. doi: 10.1093/hmg/ddw187. Epub 2016 Jul 4.

49.

Distribution of PSA-NCAM in normal, Alzheimer's and Parkinson's disease human brain.

Murray HC, Low VF, Swanson ME, Dieriks BV, Turner C, Faull RL, Curtis MA.

Neuroscience. 2016 Aug 25;330:359-75. doi: 10.1016/j.neuroscience.2016.06.003. Epub 2016 Jun 7.

PMID:
27282086
50.

Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease: metabolic basis for dementia.

Xu J, Begley P, Church SJ, Patassini S, McHarg S, Kureishy N, Hollywood KA, Waldvogel HJ, Liu H, Zhang S, Lin W, Herholz K, Turner C, Synek BJ, Curtis MA, Rivers-Auty J, Lawrence CB, Kellett KA, Hooper NM, Vardy ER, Wu D, Unwin RD, Faull RL, Dowsey AW, Cooper GJ.

Sci Rep. 2016 Jun 9;6:27524. doi: 10.1038/srep27524.

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