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Items: 1 to 50 of 415

1.

The Role of Microglia and Astrocytes in Huntington's Disease.

Palpagama TH, Waldvogel HJ, Faull RLM, Kwakowsky A.

Front Mol Neurosci. 2019 Oct 25;12:258. doi: 10.3389/fnmol.2019.00258. eCollection 2019.

2.

Altered microglia and neurovasculature in the Alzheimer's disease cerebellum.

Singh-Bains MK, Linke V, Austria MDR, Tan AYS, Scotter EL, Mehrabi NF, Faull RLM, Dragunow M.

Neurobiol Dis. 2019 Dec;132:104589. doi: 10.1016/j.nbd.2019.104589. Epub 2019 Aug 24.

PMID:
31454549
3.

Comprehensive evaluation of a prospective Australian patient cohort with suspected genetic kidney disease undergoing clinical genomic testing: a study protocol.

Jayasinghe K, Stark Z, Patel C, Mallawaarachchi A, McCarthy H, Faull R, Chakera A, Sundaram M, Jose M, Kerr P, Wu Y, Wardrop L, Goranitis I, Best S, Martyn M, Quinlan C, Mallett AJ.

BMJ Open. 2019 Aug 5;9(8):e029541. doi: 10.1136/bmjopen-2019-029541.

4.

The synthesis of a novel Crizotinib heptamethine cyanine dye conjugate that potentiates the cytostatic and cytotoxic effects of Crizotinib in patient-derived glioblastoma cell lines.

Choi PJ, Cooper E, Schweder P, Mee E, Faull R, Denny WA, Dragunow M, Park TI, Jose J.

Bioorg Med Chem Lett. 2019 Sep 15;29(18):2617-2621. doi: 10.1016/j.bmcl.2019.07.051. Epub 2019 Jul 29.

PMID:
31378572
5.

GABAA Receptors Are Well Preserved in the Hippocampus of Aged Mice.

Palpagama TH, Sagniez M, Kim S, Waldvogel HJ, Faull RL, Kwakowsky A.

eNeuro. 2019 Aug 14;6(4). pii: ENEURO.0496-18.2019. doi: 10.1523/ENEURO.0496-18.2019. Print 2019 Jul/Aug.

6.

Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington's Disease.

Patassini S, Begley P, Xu J, Church SJ, Kureishy N, Reid SJ, Waldvogel HJ, Faull RLM, Snell RG, Unwin RD, Cooper GJS.

Metabolites. 2019 Jun 11;9(6). pii: E113. doi: 10.3390/metabo9060113.

7.

Gadolinium-Free Cardiovascular Magnetic Resonance Stress T1 Mapping in Patients With Chronic Kidney Disease.

Shah R, Sree Raman K, Walls A, Woodman RJ, Faull R, Gleadle JM, Selvanayagam JB.

JACC Cardiovasc Imaging. 2019 Oct;12(10):2083-2085. doi: 10.1016/j.jcmg.2019.04.016. Epub 2019 Jun 12. No abstract available.

PMID:
31202747
8.

Vascular Dysfunction in Alzheimer's Disease: A Prelude to the Pathological Process or a Consequence of It?

Govindpani K, McNamara LG, Smith NR, Vinnakota C, Waldvogel HJ, Faull RL, Kwakowsky A.

J Clin Med. 2019 May 10;8(5). pii: E651. doi: 10.3390/jcm8050651. Review.

9.

Effects of Arteriovenous Fistula Ligation on Cardiac Structure and Function in Kidney Transplant Recipients.

Rao NN, Stokes MB, Rajwani A, Ullah S, Williams K, King D, Macaulay E, Russell CH, Olakkengil S, Carroll RP, Faull RJ, Teo KSL, McDonald SP, Worthley MI, Coates PT.

Circulation. 2019 Jun 18;139(25):2809-2818. doi: 10.1161/CIRCULATIONAHA.118.038505. Epub 2019 May 2.

PMID:
31045455
10.

End-stage renal failure is associated with impaired coronary microvascular function.

Nelson AJ, Dundon BK, Worthley SG, Richardson JD, Puri R, Wong DTL, Coates PT, Faull RJ, Worthley MI.

Coron Artery Dis. 2019 Nov;30(7):520-527. doi: 10.1097/MCA.0000000000000727.

PMID:
30883431
11.

Variable colocalisation of GABAA receptor subunits and glycine receptors on neurons in the human hypoglossal nucleus.

Waldvogel HJ, Biggins FM, Singh A, Arasaratnam CJ, Faull RLM.

J Chem Neuroanat. 2019 Apr;97:99-111. doi: 10.1016/j.jchemneu.2019.02.005. Epub 2019 Feb 27.

PMID:
30825508
12.

Cell-Type-Specific Gene Expression Profiling in Adult Mouse Brain Reveals Normal and Disease-State Signatures.

Merienne N, Meunier C, Schneider A, Seguin J, Nair SS, Rocher AB, Le Gras S, Keime C, Faull R, Pellerin L, Chatton JY, Neri C, Merienne K, Déglon N.

Cell Rep. 2019 Feb 26;26(9):2477-2493.e9. doi: 10.1016/j.celrep.2019.02.003.

13.

Prognostic Utility of Oxygen-Sensitive Cardiac Magnetic Resonance Imaging in Diabetic and Nondiabetic Chronic Kidney Disease Patients With No Known Coronary Artery Disease.

Shah R, Parnham S, Liang Z, Perry R, Bradbrook C, Smith E, Faull R, Woodman RJ, Nucifora G, Gleadle JM, Selvanayagam JB.

JACC Cardiovasc Imaging. 2019 Jun;12(6):1107-1109. doi: 10.1016/j.jcmg.2018.12.014. Epub 2019 Feb 13. No abstract available.

PMID:
30772234
14.

Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.

Dominy SS, Lynch C, Ermini F, Benedyk M, Marczyk A, Konradi A, Nguyen M, Haditsch U, Raha D, Griffin C, Holsinger LJ, Arastu-Kapur S, Kaba S, Lee A, Ryder MI, Potempa B, Mydel P, Hellvard A, Adamowicz K, Hasturk H, Walker GD, Reynolds EC, Faull RLM, Curtis MA, Dragunow M, Potempa J.

Sci Adv. 2019 Jan 23;5(1):eaau3333. doi: 10.1126/sciadv.aau3333. eCollection 2019 Jan.

15.

Regional protein expression in human Alzheimer's brain correlates with disease severity.

Xu J, Patassini S, Rustogi N, Riba-Garcia I, Hale BD, Phillips AM, Waldvogel H, Haines R, Bradbury P, Stevens A, Faull RLM, Dowsey AW, Cooper GJS, Unwin RD.

Commun Biol. 2019 Feb 4;2:43. doi: 10.1038/s42003-018-0254-9. eCollection 2019.

16.

Chemical neuroanatomy of the substantia nigra in the ovine brain.

Murray SJ, Black BL, Reid SJ, Rudiger SR, Simon Bawden C, Snell RG, Waldvogel HJ, Faull RLM.

J Chem Neuroanat. 2019 Apr;97:43-56. doi: 10.1016/j.jchemneu.2019.01.007. Epub 2019 Jan 18.

PMID:
30664938
17.

Sex- and age-related changes in GABA signaling components in the human cortex.

Pandya M, Palpagama TH, Turner C, Waldvogel HJ, Faull RL, Kwakowsky A.

Biol Sex Differ. 2019 Jan 14;10(1):5. doi: 10.1186/s13293-018-0214-6.

18.

Cerebellar degeneration correlates with motor symptoms in Huntington disease.

Singh-Bains MK, Mehrabi NF, Sehji T, Austria MDR, Tan AYS, Tippett LJ, Dragunow M, Waldvogel HJ, Faull RLM.

Ann Neurol. 2019 Mar;85(3):396-405. doi: 10.1002/ana.25413. Epub 2019 Feb 4.

19.

Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease.

Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Müller F, Scherzer CR.

Nat Neurosci. 2019 Jan;22(1):144-147. doi: 10.1038/s41593-018-0277-z.

PMID:
30482917
20.

Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease.

Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Müller F, Scherzer CR.

Nat Neurosci. 2018 Oct;21(10):1482-1492. doi: 10.1038/s41593-018-0223-0. Epub 2018 Sep 17. Erratum in: Nat Neurosci. 2019 Jan;22(1):144-147.

21.

PU.1 regulates Alzheimer's disease-associated genes in primary human microglia.

Rustenhoven J, Smith AM, Smyth LC, Jansson D, Scotter EL, Swanson MEV, Aalderink M, Coppieters N, Narayan P, Handley R, Overall C, Park TIH, Schweder P, Heppner P, Curtis MA, Faull RLM, Dragunow M.

Mol Neurodegener. 2018 Aug 20;13(1):44. doi: 10.1186/s13024-018-0277-1.

22.

Gamma-aminobutyric acid A receptors in Alzheimer's disease: highly localized remodeling of a complex and diverse signaling pathway.

Kwakowsky A, Calvo-Flores Guzmán B, Govindpani K, Waldvogel HJ, Faull RL.

Neural Regen Res. 2018 Aug;13(8):1362-1363. doi: 10.4103/1673-5374.235240. No abstract available.

23.

Markers for human brain pericytes and smooth muscle cells.

Smyth LCD, Rustenhoven J, Scotter EL, Schweder P, Faull RLM, Park TIH, Dragunow M.

J Chem Neuroanat. 2018 Oct;92:48-60. doi: 10.1016/j.jchemneu.2018.06.001. Epub 2018 Jun 7.

PMID:
29885791
24.

Stereological Methods to Quantify Cell Loss in the Huntington's Disease Human Brain.

Mehrabi NF, Singh-Bains MK, Waldvogel HJ, Faull RLM.

Methods Mol Biol. 2018;1780:1-16. doi: 10.1007/978-1-4939-7825-0_1.

PMID:
29856011
25.

Subventricular zone lipidomic architecture loss in Huntington's disease.

Hunter M, Demarais NJ, Faull RLM, Grey AC, Curtis MA.

J Neurochem. 2018 Sep;146(5):613-630. doi: 10.1111/jnc.14468. Epub 2018 Aug 8.

26.

Unique and shared inflammatory profiles of human brain endothelia and pericytes.

Smyth LCD, Rustenhoven J, Park TI, Schweder P, Jansson D, Heppner PA, O'Carroll SJ, Mee EW, Faull RLM, Curtis M, Dragunow M.

J Neuroinflammation. 2018 May 11;15(1):138. doi: 10.1186/s12974-018-1167-8.

27.

Emergence of breath testing as a new non-invasive diagnostic modality for neurodegenerative diseases.

Subramaniam NS, Bawden CS, Waldvogel H, Faull RML, Howarth GS, Snell RG.

Brain Res. 2018 Jul 15;1691:75-86. doi: 10.1016/j.brainres.2018.04.017. Epub 2018 Apr 22. Review.

PMID:
29684335
28.

Differential Fatty Acid-Binding Protein Expression in Persistent Radial Glia in the Human and Sheep Subventricular Zone.

Dieriks BV, Dean JM, Aronica E, Waldvogel HJ, Faull RLM, Curtis MA.

Dev Neurosci. 2018;40(2):145-161. doi: 10.1159/000487633. Epub 2018 Apr 20.

PMID:
29680832
29.

The GABAergic system as a therapeutic target for Alzheimer's disease.

Calvo-Flores Guzmán B, Vinnakota C, Govindpani K, Waldvogel HJ, Faull RLM, Kwakowsky A.

J Neurochem. 2018 Sep;146(6):649-669. doi: 10.1111/jnc.14345. Epub 2018 Aug 1. Review.

30.

Do arteriovenous fistulas increase cardiac risk?

Faull R, Rao N, Worthley M.

Semin Dial. 2018 Jul;31(4):357-361. doi: 10.1111/sdi.12687. Epub 2018 Mar 7. Review.

PMID:
29513901
31.

GABAA receptor subunit expression changes in the human Alzheimer's disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus.

Kwakowsky A, Calvo-Flores Guzmán B, Pandya M, Turner C, Waldvogel HJ, Faull RL.

J Neurochem. 2018 Jun;145(5):374-392. doi: 10.1111/jnc.14325.

32.

Modelling physiological and pathological conditions to study pericyte biology in brain function and dysfunction.

Rustenhoven J, Smyth LC, Jansson D, Schweder P, Aalderink M, Scotter EL, Mee EW, Faull RLM, Park TI, Dragunow M.

BMC Neurosci. 2018 Feb 22;19(1):6. doi: 10.1186/s12868-018-0405-4.

33.

Gastrointestinal symptoms in patients receiving dialysis: A systematic review.

Zuvela J, Trimingham C, Le Leu R, Faull R, Clayton P, Jesudason S, Meade A.

Nephrology (Carlton). 2018 Aug;23(8):718-727. doi: 10.1111/nep.13243.

PMID:
29468835
34.

Neurochemical Characterization of PSA-NCAM+ Cells in the Human Brain and Phenotypic Quantification in Alzheimer's Disease Entorhinal Cortex.

Murray HC, Swanson MEV, Dieriks BV, Turner C, Faull RLM, Curtis MA.

Neuroscience. 2018 Feb 21;372:289-303. doi: 10.1016/j.neuroscience.2017.12.019.

PMID:
29429526
35.

Layer-specific lipid signatures in the human subventricular zone demonstrated by imaging mass spectrometry.

Hunter M, Demarais NJ, Faull RLM, Grey AC, Curtis MA.

Sci Rep. 2018 Feb 7;8(1):2551. doi: 10.1038/s41598-018-20793-4.

36.

Bowel health in chronic kidney disease: Patient perceptions differ from clinical definitions.

Trimingham C, McDonald S, Dansie K, Jesudason S, Faull R, Clayton P, Liew G, Le Leu R, Meade A.

J Ren Care. 2018 Jun;44(2):65-72. doi: 10.1111/jorc.12230. Epub 2018 Jan 8.

PMID:
29316279
37.

Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.

Handley RR, Reid SJ, Brauning R, Maclean P, Mears ER, Fourie I, Patassini S, Cooper GJS, Rudiger SR, McLaughlan CJ, Verma PJ, Gusella JF, MacDonald ME, Waldvogel HJ, Bawden CS, Faull RLM, Snell RG.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11293-E11302. doi: 10.1073/pnas.1711243115. Epub 2017 Dec 11.

38.

GABAA and GABAB receptor subunit localization on neurochemically identified neurons of the human subthalamic nucleus.

Wu XH, Song JJ, Faull RLM, Waldvogel HJ.

J Comp Neurol. 2018 Apr 1;526(5):803-823. doi: 10.1002/cne.24368. Epub 2017 Dec 22.

PMID:
29218727
39.

A ventral glomerular deficit in Parkinson's disease revealed by whole olfactory bulb reconstruction.

Zapiec B, Dieriks BV, Tan S, Faull RLM, Mombaerts P, Curtis MA.

Brain. 2017 Oct 1;140(10):2722-2736. doi: 10.1093/brain/awx208.

40.

Metal concentrations and distributions in the human olfactory bulb in Parkinson's disease.

Gardner B, Dieriks BV, Cameron S, Mendis LHS, Turner C, Faull RLM, Curtis MA.

Sci Rep. 2017 Sep 5;7(1):10454. doi: 10.1038/s41598-017-10659-6.

41.

Towards a Better Understanding of GABAergic Remodeling in Alzheimer's Disease.

Govindpani K, Calvo-Flores Guzmán B, Vinnakota C, Waldvogel HJ, Faull RL, Kwakowsky A.

Int J Mol Sci. 2017 Aug 21;18(8). pii: E1813. doi: 10.3390/ijms18081813. Review.

42.

Alzheimer's disease markers in the aged sheep (Ovis aries).

Reid SJ, Mckean NE, Henty K, Portelius E, Blennow K, Rudiger SR, Bawden CS, Handley RR, Verma PJ, Faull RLM, Waldvogel HJ, Zetterberg H, Snell RG.

Neurobiol Aging. 2017 Oct;58:112-119. doi: 10.1016/j.neurobiolaging.2017.06.020. Epub 2017 Jun 24.

PMID:
28728117
43.

The Complexity of Clinical Huntington's Disease: Developments in Molecular Genetics, Neuropathology and Neuroimaging Biomarkers.

Tippett LJ, Waldvogel HJ, Snell RG, Vonsattel JP, Young AB, Faull RLM.

Adv Neurobiol. 2017;15:129-161. doi: 10.1007/978-3-319-57193-5_5. Review.

PMID:
28674980
44.

Evidence for widespread, severe brain copper deficiency in Alzheimer's dementia.

Xu J, Church SJ, Patassini S, Begley P, Waldvogel HJ, Curtis MA, Faull RLM, Unwin RD, Cooper GJS.

Metallomics. 2017 Aug 16;9(8):1106-1119. doi: 10.1039/c7mt00074j.

PMID:
28654115
45.

A 20-Year multi-followup longitudinal study assessing whether antipsychotic medications contribute to work functioning in schizophrenia.

Harrow M, Jobe TH, Faull RN, Yang J.

Psychiatry Res. 2017 Oct;256:267-274. doi: 10.1016/j.psychres.2017.06.069. Epub 2017 Jun 22.

46.

Effect of post-mortem delay on N-terminal huntingtin protein fragments in human control and Huntington disease brain lysates.

Schut MH, Patassini S, Kim EH, Bullock J, Waldvogel HJ, Faull RLM, Pepers BA, den Dunnen JT, van Ommen GB, van Roon-Mom WMC.

PLoS One. 2017 Jun 1;12(6):e0178556. doi: 10.1371/journal.pone.0178556. eCollection 2017.

47.

The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients.

Neueder A, Landles C, Ghosh R, Howland D, Myers RH, Faull RLM, Tabrizi SJ, Bates GP.

Sci Rep. 2017 May 2;7(1):1307. doi: 10.1038/s41598-017-01510-z.

48.

The immunohistochemical distribution of the GABAA receptor α1, α2, α3, β2/3 and γ2 subunits in the human thalamus.

Waldvogel HJ, Munkle M, van Roon-Mom W, Mohler H, Faull RLM.

J Chem Neuroanat. 2017 Jul;82:39-55. doi: 10.1016/j.jchemneu.2017.04.006. Epub 2017 Apr 23.

PMID:
28445782
49.

Impaired expression of GABA transporters in the human Alzheimer's disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus.

Fuhrer TE, Palpagama TH, Waldvogel HJ, Synek BJL, Turner C, Faull RL, Kwakowsky A.

Neuroscience. 2017 May 20;351:108-118. doi: 10.1016/j.neuroscience.2017.03.041. Epub 2017 Apr 4.

PMID:
28385633
50.

Insulin promotes cell migration by regulating PSA-NCAM.

Monzo HJ, Coppieters N, Park TIH, Dieriks BV, Faull RLM, Dragunow M, Curtis MA.

Exp Cell Res. 2017 Jun 1;355(1):26-39. doi: 10.1016/j.yexcr.2017.03.029. Epub 2017 Mar 21.

PMID:
28341445

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