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Continuous Renal Replacement Therapy Dosing in Critically Ill Patients: A Quality Improvement Initiative.

Griffin BR, Thomson A, Yoder M, Francis I, Ambruso S, Bregman A, Feller M, Johnson-Bortolotto S, King C, Bonnes D, Dufficy L, Wu C, Bansal A, Tad-Y D, Faubel S, Jalal D.

Am J Kidney Dis. 2019 Sep 17. pii: S0272-6386(19)30890-X. doi: 10.1053/j.ajkd.2019.06.013. [Epub ahead of print]


Incident infection following acute kidney injury with recovery to baseline creatinine: A propensity score matched analysis.

Griffin BR, You Z, Holmen J, SooHoo M, Gist KM, Colbert JF, Chonchol M, Faubel S, Jovanovich A.

PLoS One. 2019 Jun 24;14(6):e0217935. doi: 10.1371/journal.pone.0217935. eCollection 2019.


Matching Human Unilateral AKI, a Reverse Translational Approach to Investigate Kidney Recovery after Ischemia.

Soranno DE, Gil HW, Kirkbride-Romeo L, Altmann C, Montford JR, Yang H, Levine A, Buchanan J, Faubel S.

J Am Soc Nephrol. 2019 Jun;30(6):990-1005. doi: 10.1681/ASN.2018080808. Epub 2019 May 9.


Biomarkers of Drug-Induced Kidney Toxicity.

Griffin BR, Faubel S, Edelstein CL.

Ther Drug Monit. 2019 Apr;41(2):213-226. doi: 10.1097/FTD.0000000000000589. Review.


Metabolomics assessment reveals oxidative stress and altered energy production in the heart after ischemic acute kidney injury in mice.

Fox BM, Gil HW, Kirkbride-Romeo L, Bagchi RA, Wennersten SA, Haefner KR, Skrypnyk NI, Brown CN, Soranno DE, Gist KM, Griffin BR, Jovanovich A, Reisz JA, Wither MJ, D'Alessandro A, Edelstein CL, Clendenen N, McKinsey TA, Altmann C, Faubel S.

Kidney Int. 2019 Mar;95(3):590-610. doi: 10.1016/j.kint.2018.10.020. Epub 2019 Jan 30.


Current Status of Novel Biomarkers for the Diagnosis of Acute Kidney Injury: A Historical Perspective.

Griffin BR, Gist KM, Faubel S.

J Intensive Care Med. 2019 Jan 17:885066618824531. doi: 10.1177/0885066618824531. [Epub ahead of print]


Pulmonary Consequences of Acute Kidney Injury.

Teixeira JP, Ambruso S, Griffin BR, Faubel S.

Semin Nephrol. 2019 Jan;39(1):3-16. doi: 10.1016/j.semnephrol.2018.10.001. Review.


Effects of Baseline Thrombocytopenia and Platelet Decrease Following Renal Replacement Therapy Initiation in Patients With Severe Acute Kidney Injury.

Griffin BR, Jovanovich A, You Z, Palevsky P, Faubel S, Jalal D.

Crit Care Med. 2019 Apr;47(4):e325-e331. doi: 10.1097/CCM.0000000000003598.


Increase in chloride from baseline is independently associated with mortality in critically ill children.

Barhight MF, Brinton J, Stidham T, Soranno DE, Faubel S, Griffin BR, Goebel J, Mourani PM, Gist KM.

Intensive Care Med. 2018 Dec;44(12):2183-2191. doi: 10.1007/s00134-018-5424-1. Epub 2018 Oct 31.


Fluid Management With Peritoneal Dialysis After Pediatric Cardiac Surgery.

Barhight MF, Soranno D, Faubel S, Gist KM.

World J Pediatr Congenit Heart Surg. 2018 Nov;9(6):696-704. doi: 10.1177/2150135118800699. Review.


Acute Kidney Injury Defined by Fluid Corrected Creatinine in Neonates After the Norwood Procedure.

SooHoo MM, Patel SS, Jaggers J, Faubel S, Gist KM.

World J Pediatr Congenit Heart Surg. 2018 Sep;9(5):513-521. doi: 10.1177/2150135118775413.


Acute Kidney Injury Biomarkers Predict an Increase in Serum Milrinone Concentration Earlier Than Serum Creatinine-Defined Acute Kidney Injury in Infants After Cardiac Surgery.

Gist KM, Cooper DS, Wrona J, Faubel S, Altmann C, Gao Z, Marino BS, Alten J, Hock KM, Mizuno T, Vinks AA, Joy MS, Wempe MF, Bennett MR, Goldstein SL.

Ther Drug Monit. 2018 Apr;40(2):186-194. doi: 10.1097/FTD.0000000000000496.


Acute kidney injury is associated with subsequent infection in neonates after the Norwood procedure: a retrospective chart review.

SooHoo M, Griffin B, Jovanovich A, Soranno DE, Mack E, Patel SS, Faubel S, Gist KM.

Pediatr Nephrol. 2018 Jul;33(7):1235-1242. doi: 10.1007/s00467-018-3907-5. Epub 2018 Mar 5.


Hyperchloremia is independently associated with mortality in critically ill children who ultimately require continuous renal replacement therapy.

Barhight MF, Lusk J, Brinton J, Stidham T, Soranno DE, Faubel S, Goebel J, Mourani PM, Gist KM.

Pediatr Nephrol. 2018 Jun;33(6):1079-1085. doi: 10.1007/s00467-018-3898-2. Epub 2018 Feb 5.


The Nephrologist Has Great Potential to Have an Important Role in the Intensive Care Unit: Reply to the Letter to the Editor of David J.R. Morgan.

Askenazi DJ, Faubel S.

Blood Purif. 2017;44(4):269-270. doi: 10.1159/000478974. Epub 2017 Oct 12. No abstract available.


A model-specific role of microRNA-223 as a mediator of kidney injury during experimental sepsis.

Colbert JF, Ford JA, Haeger SM, Yang Y, Dailey KL, Allison KC, Neudecker V, Evans CM, Richardson VL, Brodsky KS, Faubel S, Eltzschig HK, Schmidt EP, Ginde AA.

Am J Physiol Renal Physiol. 2017 Aug 1;313(2):F553-F559. doi: 10.1152/ajprenal.00493.2016. Epub 2017 May 17.


Kinetics of the cell cycle arrest biomarkers (TIMP-2*IGFBP-7) for prediction of acute kidney injury in infants after cardiac surgery.

Gist KM, Goldstein SL, Wrona J, Alten JA, Basu RK, Cooper DS, Soranno DE, Duplantis J, Altmann C, Gao Z, Faubel S.

Pediatr Nephrol. 2017 Sep;32(9):1611-1619. doi: 10.1007/s00467-017-3655-y. Epub 2017 Apr 5.


Early peritoneal dialysis reduces lung inflammation in mice with ischemic acute kidney injury.

Altmann C, Ahuja N, Kiekhaefer CM, Andres Hernando A, Okamura K, Bhargava R, Duplantis J, Kirkbride-Romeo LA, Huckles J, Fox BM, Kahn K, Soranno D, Gil HW, Teitelbaum I, Faubel S.

Kidney Int. 2017 Aug;92(2):365-376. doi: 10.1016/j.kint.2017.01.020. Epub 2017 Mar 16.


Circulating IL-6 upregulates IL-10 production in splenic CD4+ T cells and limits acute kidney injury-induced lung inflammation.

Andres-Hernando A, Okamura K, Bhargava R, Kiekhaefer CM, Soranno D, Kirkbride-Romeo LA, Gil HW, Altmann C, Faubel S.

Kidney Int. 2017 May;91(5):1057-1069. doi: 10.1016/j.kint.2016.12.014. Epub 2017 Feb 14.


Optimal Role of the Nephrologist in the Intensive Care Unit.

Askenazi DJ, Heung M, Connor MJ Jr, Basu RK, Cerdá J, Doi K, Koyner JL, Bihorac A, Golestaneh L, Vijayan A, Okusa MD, Faubel S; American Society of Nephrology Acute Kidney Injury Advisory Group.

Blood Purif. 2017;43(1-3):68-77. doi: 10.1159/000452317. Epub 2016 Dec 3.


Severe Sepsis Outcomes Among Hospitalizations With Inflammatory Bowel Disease.

Colbert JF, Schmidt EP, Faubel S, Ginde AA.

Shock. 2017 Feb;47(2):128-131. doi: 10.1097/SHK.0000000000000742.


Immediate Consequences of Acute Kidney Injury: The Impact of Traditional and Nontraditional Complications on Mortality in Acute Kidney Injury.

Faubel S, Shah PB.

Adv Chronic Kidney Dis. 2016 May;23(3):179-85. doi: 10.1053/j.ackd.2016.02.007. Review.


Delivery of interleukin-10 via injectable hydrogels improves renal outcomes and reduces systemic inflammation following ischemic acute kidney injury in mice.

Soranno DE, Rodell CB, Altmann C, Duplantis J, Andres-Hernando A, Burdick JA, Faubel S.

Am J Physiol Renal Physiol. 2016 Aug 1;311(2):F362-72. doi: 10.1152/ajprenal.00579.2015. Epub 2016 Mar 9.


Bridging translation for acute kidney injury with better preclinical modeling of human disease.

Skrypnyk NI, Siskind LJ, Faubel S, de Caestecker MP.

Am J Physiol Renal Physiol. 2016 May 15;310(10):F972-84. doi: 10.1152/ajprenal.00552.2015. Epub 2016 Mar 9. Review.


Clinical Use of the Urine Biomarker [TIMP-2] × [IGFBP7] for Acute Kidney Injury Risk Assessment.

Vijayan A, Faubel S, Askenazi DJ, Cerda J, Fissell WH, Heung M, Humphreys BD, Koyner JL, Liu KD, Mour G, Nolin TD, Bihorac A; American Society of Nephrology Acute Kidney Injury Advisory Group.

Am J Kidney Dis. 2016 Jul;68(1):19-28. doi: 10.1053/j.ajkd.2015.12.033. Epub 2016 Mar 4.


A Decline in Intraoperative Renal Near-Infrared Spectroscopy Is Associated With Adverse Outcomes in Children Following Cardiac Surgery.

Gist KM, Kaufman J, da Cruz EM, Friesen RH, Crumback SL, Linders M, Edelstein C, Altmann C, Palmer C, Jalal D, Faubel S.

Pediatr Crit Care Med. 2016 Apr;17(4):342-9. doi: 10.1097/PCC.0000000000000674.


Bridging Translation by Improving Preclinical Study Design in AKI.

de Caestecker M, Humphreys BD, Liu KD, Fissell WH, Cerda J, Nolin TD, Askenazi D, Mour G, Harrell FE Jr, Pullen N, Okusa MD, Faubel S; ASN AKI Advisory Group.

J Am Soc Nephrol. 2015 Dec;26(12):2905-16. doi: 10.1681/ASN.2015070832. Epub 2015 Nov 4. Review.


Mechanisms and mediators of lung injury after acute kidney injury.

Faubel S, Edelstein CL.

Nat Rev Nephrol. 2016 Jan;12(1):48-60. doi: 10.1038/nrneph.2015.158. Epub 2015 Oct 6. Review.


Shank2 Regulates Renal Albumin Endocytosis.

Dobrinskikh E, Lewis L, Brian Doctor R, Okamura K, Lee MG, Altmann C, Faubel S, Kopp JB, Blaine J.

Physiol Rep. 2015 Sep;3(9). pii: e12510. doi: 10.14814/phy2.12510.


Outpatient Dialysis for Patients with AKI: A Policy Approach to Improving Care.

Heung M, Faubel S, Watnick S, Cruz DN, Koyner JL, Mour G, Liu KD, Cerda J, Okusa MD, Lukaszewski M, Vijayan A; American Society of Nephrology Acute Kidney Injury Advisory Group.

Clin J Am Soc Nephrol. 2015 Oct 7;10(10):1868-74. doi: 10.2215/CJN.02290215. Epub 2015 Jul 28. Review.


Promoting Kidney Function Recovery in Patients with AKI Requiring RRT.

Cerdá J, Liu KD, Cruz DN, Jaber BL, Koyner JL, Heung M, Okusa MD, Faubel S; AKI Advisory Group of the American Society of Nephrology.

Clin J Am Soc Nephrol. 2015 Oct 7;10(10):1859-67. doi: 10.2215/CJN.01170215. Epub 2015 Jul 2. Review.


Local immunotherapy via delivery of interleukin-10 and transforming growth factor β antagonist for treatment of chronic kidney disease.

Rodell CB, Rai R, Faubel S, Burdick JA, Soranno DE.

J Control Release. 2015 May 28;206:131-9. doi: 10.1016/j.jconrel.2015.03.025. Epub 2015 Mar 21.


Preparing for renal replacement therapy in patients with the Ebola virus disease.

Faubel S, Franch H, Vijayan A, Barron MA, Heung M, Liu KD, Koyner JL, Conner MJ Jr.

Blood Purif. 2014;38(3-4):276-85. doi: 10.1159/000371530. Epub 2015 Feb 11.


A pan caspase inhibitor decreases caspase-1, IL-1α and IL-1β, and protects against necrosis of cisplatin-treated freshly isolated proximal tubules.

Lee DW, Faubel S, Edelstein CL.

Ren Fail. 2015 Feb;37(1):144-50. doi: 10.3109/0886022X.2014.970194. Epub 2014 Oct 13.


Dual therapy difficulties in angiotensin blockade for proteinuria: a teachable moment.

Hung KW, Blaine J, Faubel S.

JAMA Intern Med. 2014 Sep;174(9):1429-30. doi: 10.1001/jamainternmed.2014.3460. No abstract available.


Prolonged acute kidney injury exacerbates lung inflammation at 7 days post-acute kidney injury.

Andres-Hernando A, Altmann C, Bhargava R, Okamura K, Bacalja J, Hunter B, Ahuja N, Soranno D, Faubel S.

Physiol Rep. 2014 Jul 22;2(7). pii: e12084. doi: 10.14814/phy2.12084. Print 2014 Jul 1.


The daily burden of acute kidney injury: a survey of U.S. nephrologists on World Kidney Day.

Koyner JL, Cerdá J, Goldstein SL, Jaber BL, Liu KD, Shea JA, Faubel S; Acute Kidney Injury Advisory Group of the American Society of Nephrology.

Am J Kidney Dis. 2014 Sep;64(3):394-401. doi: 10.1053/j.ajkd.2014.03.018. Epub 2014 May 9.


Renal relevant radiology: introduction.

Faubel S.

Clin J Am Soc Nephrol. 2014 Feb;9(2):371-2. doi: 10.2215/CJN.10211013. No abstract available.


Heparanase mediates renal dysfunction during early sepsis in mice.

Lygizos MI, Yang Y, Altmann CJ, Okamura K, Hernando AA, Perez MJ, Smith LP, Koyanagi DE, Gandjeva A, Bhargava R, Tuder RM, Faubel S, Schmidt EP.

Physiol Rep. 2013 Nov;1(6):e00153. doi: 10.1002/phy2.153. Epub 2013 Nov 11.


Have we reached the limit of mortality benefit with our approach to renal replacement therapy in acute kidney injury?

Faubel S.

Am J Kidney Dis. 2013 Dec;62(6):1030-3. doi: 10.1053/j.ajkd.2013.09.004. No abstract available.


Acute lung injury and acute kidney injury are established by four hours in experimental sepsis and are improved with pre, but not post, sepsis administration of TNF-α antibodies.

Bhargava R, Altmann CJ, Andres-Hernando A, Webb RG, Okamura K, Yang Y, Falk S, Schmidt EP, Faubel S.

PLoS One. 2013 Nov 12;8(11):e79037. doi: 10.1371/journal.pone.0079037. eCollection 2013.


Renal relevant radiology: use of ultrasonography in patients with AKI.

Faubel S, Patel NU, Lockhart ME, Cadnapaphornchai MA.

Clin J Am Soc Nephrol. 2014 Feb;9(2):382-94. doi: 10.2215/CJN.04840513. Epub 2013 Nov 14. Review.


Obesity development in caspase-1-deficient mice.

Wang H, Capell W, Yoon JH, Faubel S, Eckel RH.

Int J Obes (Lond). 2014 Jan;38(1):152-5. doi: 10.1038/ijo.2013.59. Epub 2013 Apr 24.


Intratracheal IL-6 protects against lung inflammation in direct, but not indirect, causes of acute lung injury in mice.

Bhargava R, Janssen W, Altmann C, Andrés-Hernando A, Okamura K, Vandivier RW, Ahuja N, Faubel S.

PLoS One. 2013 May 8;8(5):e61405. doi: 10.1371/journal.pone.0061405. Print 2013.


AKI transition of care: a potential opportunity to detect and prevent CKD.

Goldstein SL, Jaber BL, Faubel S, Chawla LS; Acute Kidney Injury Advisory Group of American Society of Nephrology.

Clin J Am Soc Nephrol. 2013 Mar;8(3):476-83. doi: 10.2215/CJN.12101112. Review.


Endocytosis of albumin by podocytes elicits an inflammatory response and induces apoptotic cell death.

Okamura K, Dummer P, Kopp J, Qiu L, Levi M, Faubel S, Blaine J.

PLoS One. 2013;8(1):e54817. doi: 10.1371/journal.pone.0054817. Epub 2013 Jan 28.


Urine IL-18, NGAL, IL-8 and serum IL-8 are biomarkers of acute kidney injury following liver transplantation.

Sirota JC, Walcher A, Faubel S, Jani A, McFann K, Devarajan P, Davis CL, Edelstein CL.

BMC Nephrol. 2013 Jan 17;14:17. doi: 10.1186/1471-2369-14-17.


Circulating IL-6 mediates lung injury via CXCL1 production after acute kidney injury in mice.

Ahuja N, Andres-Hernando A, Altmann C, Bhargava R, Bacalja J, Webb RG, He Z, Edelstein CL, Faubel S.

Am J Physiol Renal Physiol. 2012 Sep 15;303(6):F864-72. doi: 10.1152/ajprenal.00025.2012. Epub 2012 Jul 11.


Cytokine production increases and cytokine clearance decreases in mice with bilateral nephrectomy.

Andres-Hernando A, Dursun B, Altmann C, Ahuja N, He Z, Bhargava R, Edelstein CE, Jani A, Hoke TS, Klein C, Faubel S.

Nephrol Dial Transplant. 2012 Dec;27(12):4339-47. doi: 10.1093/ndt/gfs256. Epub 2012 Jul 9.


Complement activation and toll-like receptor-2 signaling contribute to cytokine production after renal ischemia/reperfusion.

Amura CR, Renner B, Lyubchenko T, Faubel S, Simonian PL, Thurman JM.

Mol Immunol. 2012 Oct;52(3-4):249-57. doi: 10.1016/j.molimm.2012.05.020. Epub 2012 Jun 27.

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