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Items: 12

1.

Kub5-Hera RPRD1B Deficiency Promotes "BRCAness" and Vulnerability to PARP Inhibition in BRCA-proficient Breast Cancers.

Motea EA, Fattah FJ, Xiao L, Girard L, Rommel A, Morales JC, Patidar P, Zhou Y, Porter A, Xie Y, Minna JD, Boothman DA.

Clin Cancer Res. 2018 Aug 14. doi: 10.1158/1078-0432.CCR-17-1118. [Epub ahead of print]

PMID:
30108102
2.

TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer.

Gong K, Guo G, Gerber DE, Gao B, Peyton M, Huang C, Minna JD, Hatanpaa KJ, Kernstine K, Cai L, Xie Y, Zhu H, Fattah FJ, Zhang S, Takahashi M, Mukherjee B, Burma S, Dowell J, Dao K, Papadimitrakopoulou VA, Olivas V, Bivona TG, Zhao D, Habib AA.

J Clin Invest. 2018 Jun 1;128(6):2500-2518. doi: 10.1172/JCI96148. Epub 2018 May 7.

3.

The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair.

Patidar PL, Motea EA, Fattah FJ, Zhou Y, Morales JC, Xie Y, Garner HR, Boothman DA.

Nucleic Acids Res. 2016 Feb 29;44(4):1718-31. doi: 10.1093/nar/gkv1492. Epub 2016 Jan 26.

4.

Phase 1 study of romidepsin plus erlotinib in advanced non-small cell lung cancer.

Gerber DE, Boothman DA, Fattah FJ, Dong Y, Zhu H, Skelton RA, Priddy LL, Vo P, Dowell JE, Sarode V, Leff R, Meek C, Xie Y, Schiller JH.

Lung Cancer. 2015 Dec;90(3):534-41. doi: 10.1016/j.lungcan.2015.10.008. Epub 2015 Oct 9.

5.

NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone.

Moore Z, Chakrabarti G, Luo X, Ali A, Hu Z, Fattah FJ, Vemireddy R, DeBerardinis RJ, Brekken RA, Boothman DA.

Cell Death Dis. 2015 Jan 15;6:e1599. doi: 10.1038/cddis.2014.564.

6.

The transcription factor TFII-I promotes DNA translesion synthesis and genomic stability.

Fattah FJ, Hara K, Fattah KR, Yang C, Wu N, Warrington R, Chen DJ, Zhou P, Boothman DA, Yu H.

PLoS Genet. 2014 Jun 12;10(6):e1004419. doi: 10.1371/journal.pgen.1004419. eCollection 2014 Jun.

7.

Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair.

Morales JC, Richard P, Rommel A, Fattah FJ, Motea EA, Patidar PL, Xiao L, Leskov K, Wu SY, Hittelman WN, Chiang CM, Manley JL, Boothman DA.

Nucleic Acids Res. 2014 Apr;42(8):4996-5006. doi: 10.1093/nar/gku160. Epub 2014 Mar 3.

8.

Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.

Morales J, Li L, Fattah FJ, Dong Y, Bey EA, Patel M, Gao J, Boothman DA.

Crit Rev Eukaryot Gene Expr. 2014;24(1):15-28. Review.

9.

A role for XLF in DNA repair and recombination in human somatic cells.

Fattah FJ, Kweon J, Wang Y, Lee EH, Kan Y, Lichter N, Weisensel N, Hendrickson EA.

DNA Repair (Amst). 2014 Mar;15:39-53. doi: 10.1016/j.dnarep.2013.12.006. Epub 2014 Jan 21.

10.

Ku70, an essential gene, modulates the frequency of rAAV-mediated gene targeting in human somatic cells.

Fattah FJ, Lichter NF, Fattah KR, Oh S, Hendrickson EA.

Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8703-8. doi: 10.1073/pnas.0712060105. Epub 2008 Jun 18.

11.

Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86.

Myung K, Ghosh G, Fattah FJ, Li G, Kim H, Dutia A, Pak E, Smith S, Hendrickson EA.

Mol Cell Biol. 2004 Jun;24(11):5050-9.

12.

A comparative study of the immunity region of lambdoid phages including Shiga-toxin-converting phages: molecular basis for cross immunity.

Fattah KR, Mizutani S, Fattah FJ, Matsushiro A, Sugino Y.

Genes Genet Syst. 2000 Oct;75(5):223-32.

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