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The applause sign in frontotemporal lobar degeneration and related conditions.

Schönecker S, Hell F, Bötzel K, Wlasich E, Ackl N, Süßmair C; German FTLD Consortium, Otto M, Anderl-Straub S, Ludolph A, Kassubek J, Huppertz HJ, Diehl-Schmid J, Riedl L, Roßmeier C, Fassbender K, Lyros E, Kornhuber J, Oberstein TJ, Fliessbach K, Schneider A, Schroeter ML, Prudlo J, Lauer M, Jahn H, Levin J, Danek A.

J Neurol. 2018 Dec 1. doi: 10.1007/s00415-018-9134-y. [Epub ahead of print]


Simulation and Experimental Characterization of Lateral Imaging Resolution of Ultrasound Systems and Assessment of System Suitability for Acoustic Optic Nerve Sheath Diameter Measurement.

Lochner P, Behnke S, Fassbender K, Andrejewski A, Knodel S, Siniscalchi A, Jenderka KV, Lemor R.

J Neuroimaging. 2018 Nov 20. doi: 10.1111/jon.12578. [Epub ahead of print]


B-Mode Transorbital Ultrasonography for the Diagnosis of Idiopathic Intracranial Hypertension: A Systematic Review and Meta-Analysis.

Lochner P, Fassbender K, Knodel S, Andrejewski A, Lesmeister M, Wagenpfeil G, Nardone R, Brigo F.

Ultraschall Med. 2018 Oct 22. doi: 10.1055/a-0719-4903. [Epub ahead of print]


Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain.

Ma Q, Ries M, Decker Y, Müller A, Riner C, Bücker A, Fassbender K, Detmar M, Proulx ST.

Acta Neuropathol. 2018 Oct 10. doi: 10.1007/s00401-018-1916-x. [Epub ahead of print]


A punch in the gut - Intestinal inflammation links environmental factors to neurodegeneration in Parkinson's disease.

Becker A, Faßbender K, Oertel WH, Unger MM.

Parkinsonism Relat Disord. 2018 Sep 29. pii: S1353-8020(18)30428-0. doi: 10.1016/j.parkreldis.2018.09.032. [Epub ahead of print]


Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase.

Oeckl P, Weydt P, Steinacker P, Anderl-Straub S, Nordin F, Volk AE, Diehl-Schmid J, Andersen PM, Kornhuber J, Danek A, Fassbender K, Fliessbach K; German Consortium for Frontotemporal Lobar Degeneration, Jahn H, Lauer M, Müller K, Knehr A, Prudlo J, Schneider A, Thal DR, Yilmazer-Hanke D, Weishaupt JH, Ludolph AC, Otto M.

J Neurol Neurosurg Psychiatry. 2019 Jan;90(1):4-10. doi: 10.1136/jnnp-2018-318868. Epub 2018 Sep 17.


Serum neurofilament light chain in behavioral variant frontotemporal dementia.

Steinacker P, Anderl-Straub S, Diehl-Schmid J, Semler E, Uttner I, von Arnim CAF, Barthel H, Danek A, Fassbender K, Fliessbach K, Foerstl H, Grimmer T, Huppertz HJ, Jahn H, Kassubek J, Kornhuber J, Landwehrmeyer B, Lauer M, Maler JM, Mayer B, Oeckl P, Prudlo J, Schneider A, Volk AE, Wiltfang J, Schroeter ML, Ludolph AC, Otto M; FTLDc study group.

Neurology. 2018 Oct 9;91(15):e1390-e1401. doi: 10.1212/WNL.0000000000006318. Epub 2018 Sep 12.


Mobile Stroke Units - Cost-Effective or Just an Expensive Hype?

Walter S, Grunwald IQ, Helwig SA, Ragoschke-Schumm A, Kettner M, Fousse M, Lesmeister M, Fassbender K.

Curr Atheroscler Rep. 2018 Aug 29;20(10):49. doi: 10.1007/s11883-018-0751-9. Review.


Air-Mobile Stroke Unit for access to stroke treatment in rural regions.

Walter S, Zhao H, Easton D, Bil C, Sauer J, Liu Y, Lesmeister M, Grunwald IQ, Donnan GA, Davis SM, Fassbender K.

Int J Stroke. 2018 Aug;13(6):568-575. doi: 10.1177/1747493018784450.


Ginkgo biloba Extract EGb 761 and Its Specific Components Elicit Protective Protein Clearance Through the Autophagy-Lysosomal Pathway in Tau-Transgenic Mice and Cultured Neurons.

Qin Y, Zhang Y, Tomic I, Hao W, Menger MD, Liu C, Fassbender K, Liu Y.

J Alzheimers Dis. 2018;65(1):243-263. doi: 10.3233/JAD-180426.


Hyperacute stroke management is coming … one Mississippi, two Mississippi.

Fassbender K, Sheth KN.

Neurology. 2018 Aug 7;91(6):245-246. doi: 10.1212/WNL.0000000000005934. Epub 2018 Jul 11. No abstract available.


Mobile stroke unit use for prehospital stroke treatment-an update.

Walter S, Ragoschke-Schumm A, Lesmeister M, Helwig SA, Kettner M, Grunwald IQ, Fassbender K.

Radiologe. 2018 Nov;58(Suppl 1):24-28. doi: 10.1007/s00117-018-0408-2. Review.


MIBG scintigraphy of the major salivary glands in multiple system atrophy.

Soboll L, Leppert D, Dillmann U, Schaefer-Schuler A, Fassbender K, Ezziddin S, Spiegel J.

Parkinsonism Relat Disord. 2018 Aug;53:112-114. doi: 10.1016/j.parkreldis.2018.04.034. Epub 2018 May 4.


Specific serum and CSF microRNA profiles distinguish sporadic behavioural variant of frontotemporal dementia compared with Alzheimer patients and cognitively healthy controls.

Denk J, Oberhauser F, Kornhuber J, Wiltfang J, Fassbender K, Schroeter ML, Volk AE, Diehl-Schmid J, Prudlo J, Danek A, Landwehrmeyer B, Lauer M, Otto M, Jahn H; FTLDc study group.

PLoS One. 2018 May 10;13(5):e0197329. doi: 10.1371/journal.pone.0197329. eCollection 2018.


A language-based sum score for the course and therapeutic intervention in primary progressive aphasia.

Semler E, Anderl-Straub S, Uttner I, Diehl-Schmid J, Danek A, Einsiedler B, Fassbender K, Fliessbach K, Huppertz HJ, Jahn H, Kornhuber J, Landwehrmeyer B, Lauer M, Muche R, Prudlo J, Schneider A, Schroeter ML, Ludolph AC, Otto M; FTLD consortium.

Alzheimers Res Ther. 2018 Apr 25;10(1):41. doi: 10.1186/s13195-018-0345-3.


Association of Schizotypy With Dimensions of Cognitive Control: A Meta-Analysis.

Steffens M, Meyhöfer I, Fassbender K, Ettinger U, Kambeitz J.

Schizophr Bull. 2018 Oct 15;44(suppl_2):S512-S524. doi: 10.1093/schbul/sby030.


Assay for improved detection of antigen-specific immune cells from extrasanguinous fluids.

Schub D, Fousse M, Elsäßer J, Faßbender K, Sester U, Schmidt T, Sester M.

Eur J Immunol. 2018 Aug;48(8):1412-1414. doi: 10.1002/eji.201847490. Epub 2018 Apr 23.


Fecal markers of intestinal inflammation and intestinal permeability are elevated in Parkinson's disease.

Schwiertz A, Spiegel J, Dillmann U, Grundmann D, Bürmann J, Faßbender K, Schäfer KH, Unger MM.

Parkinsonism Relat Disord. 2018 May;50:104-107. doi: 10.1016/j.parkreldis.2018.02.022. Epub 2018 Feb 12.


A Modified Reading the Mind in the Eyes Test Predicts Behavioral Variant Frontotemporal Dementia Better Than Executive Function Tests.

Schroeter ML, Pawelke S, Bisenius S, Kynast J, Schuemberg K, Polyakova M, Anderl-Straub S, Danek A, Fassbender K, Jahn H, Jessen F, Kornhuber J, Lauer M, Prudlo J, Schneider A, Uttner I, Thöne-Otto A, Otto M, Diehl-Schmid J.

Front Aging Neurosci. 2018 Jan 30;10:11. doi: 10.3389/fnagi.2018.00011. eCollection 2018.


Author response: Standard operating procedures improve acute neurologic care in a sub-Saharan African setting.

Fassbender K, Helwig SA, Jaiteh LES, Nyan O.

Neurology. 2018 Jan 9;90(2):100. doi: 10.1212/WNL.0000000000004790. No abstract available.


Consensus Development Conference: Promoting Access to Quality Palliative Care in Canada.

Fassbender K.

J Palliat Med. 2018 Jan;21(S1):S1-S8. doi: 10.1089/jpm.2017.0453.


Rapid Review and Synthesis of the Palliative Care Matters Scientific Evidence.

Sims M, Fassbender K.

J Palliat Med. 2018 Jan;21(S1):S15-S19. doi: 10.1089/jpm.2017.0389.


Evaluating Public Engagement for a Consensus Development Conference.

Chan M, Fassbender K.

J Palliat Med. 2018 Jan;21(S1):S20-S26. doi: 10.1089/jpm.2017.0390.


Analysis of the vasculature by immunohistochemistry in paraffin-embedded brains.

Decker Y, Müller A, Németh E, Schulz-Schaeffer WJ, Fatar M, Menger MD, Liu Y, Fassbender K.

Brain Struct Funct. 2018 Mar;223(2):1001-1015. doi: 10.1007/s00429-017-1595-8. Epub 2017 Dec 19.


Ocular ultrasound for monitoring pseudotumor cerebri syndrome.

Lochner P, Fassbender K, Lesmeister M, Nardone R, Orioli A, Brigo F, Stolz E.

J Neurol. 2018 Feb;265(2):356-361. doi: 10.1007/s00415-017-8699-1. Epub 2017 Dec 14.


Behaviors in Advance Care Planning and ACtions Survey (BACPACS): development and validation part 1.

Kassam A, Douglas ML, Simon J, Cunningham S, Fassbender K, Shaw M, Davison SN.

BMC Palliat Care. 2017 Nov 22;16(1):56. doi: 10.1186/s12904-017-0236-6.


Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression.

Steinacker P, Verde F, Fang L, Feneberg E, Oeckl P, Roeber S, Anderl-Straub S, Danek A, Diehl-Schmid J, Fassbender K, Fliessbach K, Foerstl H, Giese A, Jahn H, Kassubek J, Kornhuber J, Landwehrmeyer GB, Lauer M, Pinkhardt EH, Prudlo J, Rosenbohm A, Schneider A, Schroeter ML, Tumani H, von Arnim CAF, Weishaupt J, Weydt P, Ludolph AC, Yilmazer Hanke D, Otto M; FTLDc study group.

J Neurol Neurosurg Psychiatry. 2018 Mar;89(3):239-247. doi: 10.1136/jnnp-2017-317138. Epub 2017 Nov 15.


Blockade of Experimental Multiple Sclerosis by Inhibition of the Acid Sphingomyelinase/Ceramide System.

Becker KA, Halmer R, Davies L, Henry BD, Ziobro-Henry R, Decker Y, Liu Y, Gulbins E, Fassbender K, Walter S.

Neurosignals. 2017;25(1):88-97. doi: 10.1159/000484621. Epub 2017 Nov 6.


Prehospital Computed Tomography Angiography in Acute Stroke Management.

Kettner M, Helwig SA, Ragoschke-Schumm A, Schwindling L, Roumia S, Keller I, Martens D, Kulikovski J, Manitz M, Lesmeister M, Walter S, Grunwald IQ, Schlechtriemen T, Reith W, Fassbender K.

Cerebrovasc Dis. 2017;44(5-6):338-343. doi: 10.1159/000484097. Epub 2017 Oct 31.


Longitudinal Assessment of Transorbital Sonography, Visual Acuity, and Biomarkers for Inflammation and Axonal Injury in Optic Neuritis.

Lochner P, Cantello R, Fassbender K, Lesmeister M, Nardone R, Siniscalchi A, Clemente N, Naldi A, Coppo L, Brigo F, Comi C.

Dis Markers. 2017;2017:5434310. doi: 10.1155/2017/5434310. Epub 2017 Sep 11.


Regulation of Arthritis Severity by the Acid Sphingomyelinase.

Beckmann N, Becker KA, Walter S, Becker JU, Kramer M, Hessler G, Weber S, Göthert JR, Fassbender K, Gulbins E, Carpinteiro A.

Cell Physiol Biochem. 2017;43(4):1460-1471. doi: 10.1159/000481968. Epub 2017 Oct 16.


The PRE-hospital Stroke Treatment Organization.

Audebert H, Fassbender K, Hussain MS, Ebinger M, Turc G, Uchino K, Davis S, Alexandrov A, Grotta J; PRESTO Group.

Int J Stroke. 2017 Dec;12(9):932-940. doi: 10.1177/1747493017729268. Epub 2017 Sep 5. Review.


CTLA-4-expression on VZV-specific T cells in CSF and blood is specifically increased in patients with VZV related central nervous system infections.

Schub D, Fousse M, Faßbender K, Gärtner BC, Sester U, Sester M, Schmidt T.

Eur J Immunol. 2018 Jan;48(1):151-160. doi: 10.1002/eji.201747079. Epub 2017 Sep 14.


[Requirements of neurologists for autopsies].

Schulz-Schaeffer WJ, Dillmann U, Faßbender K, Wrede A.

Pathologe. 2017 Sep;38(5):387-393. doi: 10.1007/s00292-017-0336-3. Review. German.


Acute Occlusions of Dual-Layer Carotid Stents After Endovascular Emergency Treatment of Tandem Lesions.

Yilmaz U, Körner H, Mühl-Benninghaus R, Simgen A, Kraus C, Walter S, Behnke S, Faßbender K, Reith W, Unger MM.

Stroke. 2017 Aug;48(8):2171-2175. doi: 10.1161/STROKEAHA.116.015965. Epub 2017 Jul 5.


Volunteer navigation partnerships: Piloting a compassionate community approach to early palliative care.

Pesut B, Duggleby W, Warner G, Fassbender K, Antifeau E, Hooper B, Greig M, Sullivan K.

BMC Palliat Care. 2017 Jul 3;17(1):2. doi: 10.1186/s12904-017-0210-3. Erratum in: BMC Palliat Care. 2017 Oct 10;16(1):51.


Facial emotion recognition in Parkinson's disease: Association with age and olfaction.

Kalampokini S, Lyros E, Luley M, Schöpe J, Spiegel J, Bürmann J, Dillmann U, Fassbender K, Unger MM.

J Clin Exp Neuropsychol. 2018 Apr;40(3):274-284. doi: 10.1080/13803395.2017.1341470. Epub 2017 Jun 21.


Standard operating procedures improve acute neurologic care in a sub-Saharan African setting.

Jaiteh LES, Helwig SA, Jagne A, Ragoschke-Schumm A, Sarr C, Walter S, Lesmeister M, Manitz M, Blaß S, Weis S, Schlund V, Bah N, Kauffmann J, Fousse M, Kangankan S, Ramos Cabrera A, Kronfeld K, Ruckes C, Liu Y, Nyan O, Fassbender K.

Neurology. 2017 Jul 11;89(2):144-152. doi: 10.1212/WNL.0000000000004080. Epub 2017 Jun 9.


Acid sphingomyelinase deficiency enhances myelin repair after acute and chronic demyelination.

Chami M, Halmer R, Schnoeder L, Anne Becker K, Meier C, Fassbender K, Gulbins E, Walter S.

PLoS One. 2017 Jun 5;12(6):e0178622. doi: 10.1371/journal.pone.0178622. eCollection 2017.


Dosage Calculation for Intravenous Thrombolysis of Ischemic Stroke: To Weigh or to Estimate.

Ragoschke-Schumm A, Razouk A, Lesmeister M, Helwig S, Grunwald IQ, Fassbender K.

Cerebrovasc Dis Extra. 2017;7(2):103-110. doi: 10.1159/000474955. Epub 2017 May 30.


Diagnosis and classification of optic neuropathies.

Lochner P, Brigo F, Nardone R, Lesmeister M, Fassbender K.

Lancet Neurol. 2017 May;16(5):342-343. doi: 10.1016/S1474-4422(17)30092-3. No abstract available.


Poly-GP in cerebrospinal fluid links C9orf72-associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD.

Lehmer C, Oeckl P, Weishaupt JH, Volk AE, Diehl-Schmid J, Schroeter ML, Lauer M, Kornhuber J, Levin J, Fassbender K, Landwehrmeyer B; German Consortium for Frontotemporal Lobar Degeneration, Schludi MH, Arzberger T, Kremmer E, Flatley A, Feederle R, Steinacker P, Weydt P, Ludolph AC, Edbauer D, Otto M.

EMBO Mol Med. 2017 Jul;9(7):859-868. doi: 10.15252/emmm.201607486.


Predictive Impact of Clinical Benefit in Chemotherapy-treated Advanced Pancreatic Cancer Patients in Northern Alberta.

Kim CA, Chu QSC, Fassbender K, Ghosh S, Spratlin JL.

Am J Clin Oncol. 2018 Sep;41(9):867-873. doi: 10.1097/COC.0000000000000385.


Disease-Specific Regions Outperform Whole-Brain Approaches in Identifying Progressive Supranuclear Palsy: A Multicentric MRI Study.

Mueller K, Jech R, Bonnet C, Tintěra J, Hanuška J, Möller HE, Fassbender K, Ludolph A, Kassubek J, Otto M, Růžička E, Schroeter ML; FTLDc Study Group.

Front Neurosci. 2017 Mar 7;11:100. doi: 10.3389/fnins.2017.00100. eCollection 2017.


Mobile stroke units for prehospital thrombolysis, triage, and beyond: benefits and challenges.

Fassbender K, Grotta JC, Walter S, Grunwald IQ, Ragoschke-Schumm A, Saver JL.

Lancet Neurol. 2017 Mar;16(3):227-237. doi: 10.1016/S1474-4422(17)30008-X. Epub 2017 Feb 15. Review. Erratum in: Lancet Neurol. 2017 Apr;16(4):261.


Predicting primary progressive aphasias with support vector machine approaches in structural MRI data.

Bisenius S, Mueller K, Diehl-Schmid J, Fassbender K, Grimmer T, Jessen F, Kassubek J, Kornhuber J, Landwehrmeyer B, Ludolph A, Schneider A, Anderl-Straub S, Stuke K, Danek A, Otto M, Schroeter ML; FTLDc study group.

Neuroimage Clin. 2017 Feb 6;14:334-343. doi: 10.1016/j.nicl.2017.02.003. eCollection 2017.


Neurofilament as a blood marker for diagnosis and monitoring of primary progressive aphasias.

Steinacker P, Semler E, Anderl-Straub S, Diehl-Schmid J, Schroeter ML, Uttner I, Foerstl H, Landwehrmeyer B, von Arnim CA, Kassubek J, Oeckl P, Huppertz HJ, Fassbender K, Fliessbach K, Prudlo J, Roßmeier C, Kornhuber J, Schneider A, Volk AE, Lauer M, Danek A, Ludolph AC, Otto M; FTLDc Study Group.

Neurology. 2017 Mar 7;88(10):961-969. doi: 10.1212/WNL.0000000000003688. Epub 2017 Feb 8.


Measuring Advance Care Planning: Optimizing the Advance Care Planning Engagement Survey.

Sudore RL, Heyland DK, Barnes DE, Howard M, Fassbender K, Robinson CA, Boscardin J, You JJ.

J Pain Symptom Manage. 2017 Apr;53(4):669-681.e8. doi: 10.1016/j.jpainsymman.2016.10.367. Epub 2016 Dec 29.


Doctors, Lawyers and Advance Care Planning: Time for Innovation to Work Together to Meet Client Needs.

Ries NM, Douglas M, Simon J, Fassbender K.

Healthc Policy. 2016 Nov;12(2):12-18.


e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients.

Nagel S, Sinha D, Day D, Reith W, Chapot R, Papanagiotou P, Warburton EA, Guyler P, Tysoe S, Fassbender K, Walter S, Essig M, Heidenrich J, Konstas AA, Harrison M, Papadakis M, Greveson E, Joly O, Gerry S, Maguire H, Roffe C, Hampton-Till J, Buchan AM, Grunwald IQ.

Int J Stroke. 2017 Aug;12(6):615-622. doi: 10.1177/1747493016681020. Epub 2016 Dec 1.


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