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Prehospital Stroke Management Optimized by Use of Clinical Scoring vs Mobile Stroke Unit for Triage of Patients With Stroke: A Randomized Clinical Trial.

Helwig SA, Ragoschke-Schumm A, Schwindling L, Kettner M, Roumia S, Kulikovski J, Keller I, Manitz M, Martens D, Grün D, Walter S, Lesmeister M, Ewen K, Brand J, Fousse M, Kauffmann J, Zimmer VC, Mathur S, Bertsch T, Guldner J, Magull-Seltenreich A, Binder A, Spüntrup E, Chatzikonstantinou A, Adam O, Kronfeld K, Liu Y, Ruckes C, Schumacher H, Grunwald IQ, Yilmaz U, Schlechtriemen T, Reith W, Fassbender K.

JAMA Neurol. 2019 Sep 3. doi: 10.1001/jamaneurol.2019.2829. [Epub ahead of print]


Optic nerve sheath diameter: present and future perspectives for neurologists and critical care physicians.

Lochner P, Czosnyka M, Naldi A, Lyros E, Pelosi P, Mathur S, Fassbender K, Robba C.

Neurol Sci. 2019 Jul 31. doi: 10.1007/s10072-019-04015-x. [Epub ahead of print]


MIBG scintigraphy of the major salivary glands in progressive supranuclear palsy and corticobasal degeneration.

Schubert E, Dogan S, Dillmann U, Schaefer-Schuler A, Fassbender K, Ezziddin S, Spiegel J.

Parkinsonism Relat Disord. 2019 Jul 6. pii: S1353-8020(19)30293-7. doi: 10.1016/j.parkreldis.2019.07.003. [Epub ahead of print] No abstract available.


Early poststroke seizures following thrombolysis and/or thrombectomy for acute stroke: Clinical and stroke characteristics.

Brigo F, Schneider M, Wagenpfeil G, Unger MM, Holzhoffer C, Walter S, Faßbender K, Lochner P.

Epilepsy Behav. 2019 Jun 20. pii: S1525-5050(19)30249-5. doi: 10.1016/j.yebeh.2019.05.048. [Epub ahead of print]


Collateral Automation for Triage in Stroke: Evaluating Automated Scoring of Collaterals in Acute Stroke on Computed Tomography Scans.

Grunwald IQ, Kulikovski J, Reith W, Gerry S, Namias R, Politi M, Papanagiotou P, Essig M, Mathur S, Joly O, Hussain K, Wagner V, Shah S, Harston G, Vlahovic J, Walter S, Podlasek A, Fassbender K.

Cerebrovasc Dis. 2019 Jun 19:1-6. doi: 10.1159/000500076. [Epub ahead of print]


Intravenous thrombolysis with tPA and cortical involvement increase the risk of early poststroke seizures: Results of a case-control study.

Brigo F, Schneider M, Wagenpfeil G, Ragoschke-Schumm A, Fousse M, Holzhoffer C, Nardone R, Faßbender K, Lochner P.

Epilepsy Behav. 2019 Jun 7. pii: S1525-5050(19)30250-1. doi: 10.1016/j.yebeh.2019.04.056. [Epub ahead of print]


How to increase public participation in advance care planning: findings from a World Café to elicit community group perspectives.

Biondo PD, King S, Minhas B, Fassbender K, Simon JE; Advance Care Planning Collaborative Research and Innovation Opportunities Program (ACP CRIO).

BMC Public Health. 2019 Jun 3;19(1):679. doi: 10.1186/s12889-019-7034-4.


[Mobile Stoke Unit : Changes in the concept of stroke care over time].

Kettner M, Walter S, Fassbender K.

Radiologe. 2019 Jul;59(7):622-626. doi: 10.1007/s00117-019-0548-z. Review. German.


Neurofilament light chain as a blood biomarker to differentiate psychiatric disorders from behavioural variant frontotemporal dementia.

Al Shweiki MR, Steinacker P, Oeckl P, Hengerer B, Danek A, Fassbender K, Diehl-Schmid J, Jahn H, Anderl-Straub S, Ludolph AC, Schönfeldt-Lecuona C, Otto M.

J Psychiatr Res. 2019 Jun;113:137-140. doi: 10.1016/j.jpsychires.2019.03.019. Epub 2019 Mar 24.


Technical note: can resting state functional MRI assist in routine clinical diagnosis?

Harman P, Law C, Pardhan S, Lin ZH, Johnson M, Walter S, Fassbender K, Aspinall R, Grunwald IQ.

BJR Case Rep. 2018 Dec;4(4):20180030. doi: 10.1259/bjrcr.20180030. Epub 2018 Jun 30.


Unraveling corticobasal syndrome and alien limb syndrome with structural brain imaging.

Albrecht F, Mueller K, Ballarini T, Lampe L, Diehl-Schmid J, Fassbender K, Fliessbach K, Jahn H, Jech R, Kassubek J, Kornhuber J, Landwehrmeyer B, Lauer M, Ludolph AC, Lyros E, Prudlo J, Schneider A, Synofzik M, Wiltfang J, Danek A, Otto M; FTLD-Consortium, Schroeter ML.

Cortex. 2019 Aug;117:33-40. doi: 10.1016/j.cortex.2019.02.015. Epub 2019 Feb 25.


Improving Prehospital Stroke Services in Rural and Underserved Settings With Mobile Stroke Units.

Mathur S, Walter S, Grunwald IQ, Helwig SA, Lesmeister M, Fassbender K.

Front Neurol. 2019 Mar 1;10:159. doi: 10.3389/fneur.2019.00159. eCollection 2019. Review.


Legionnaire's-disease-associated meningoencephalitis: A case report.

Grün D, Unger MM, Kauffmann J, Zimmer V, Fassbender K, Fousse M.

Pulmonology. 2019 Mar - Apr;25(2):128-130. doi: 10.1016/j.pulmoe.2018.12.006. Epub 2019 Feb 16. No abstract available.


FDG-PET underscores the key role of the thalamus in frontotemporal lobar degeneration caused by C9ORF72 mutations.

Diehl-Schmid J, Licata A, Goldhardt O, Förstl H, Yakushew I, Otto M, Anderl-Straub S, Beer A, Ludolph AC, Landwehrmeyer GB, Levin J, Danek A, Fliessbach K, Spottke A, Fassbender K, Lyros E, Prudlo J, Krause BJ, Volk A, Edbauer D, Schroeter ML, Drzezga A, Kornhuber J, Lauer M; FTLDc Study Group, Grimmer T.

Transl Psychiatry. 2019 Jan 31;9(1):54. doi: 10.1038/s41398-019-0381-1.


Response to the Letter to the Editor by the Authors of: Mobile Stroke Units-Cost-Effective or Just an Expensive Hype?

Walter S, Grunwald IQ, Helwig SA, Ragoschke-Schumm A, Kettner M, Fousse M, Lesmeister M, Fassbender K.

Curr Atheroscler Rep. 2019 Jan 25;21(2):6. doi: 10.1007/s11883-019-0765-y. Review. No abstract available.


Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology.

Liu Y, Fassbender K.

Theranostics. 2018 Dec 1;8(22):6355-6356. doi: 10.7150/thno.30953. eCollection 2018.


The applause sign in frontotemporal lobar degeneration and related conditions.

Schönecker S, Hell F, Bötzel K, Wlasich E, Ackl N, Süßmair C; German FTLD Consortium, Otto M, Anderl-Straub S, Ludolph A, Kassubek J, Huppertz HJ, Diehl-Schmid J, Riedl L, Roßmeier C, Fassbender K, Lyros E, Kornhuber J, Oberstein TJ, Fliessbach K, Schneider A, Schroeter ML, Prudlo J, Lauer M, Jahn H, Levin J, Danek A.

J Neurol. 2019 Feb;266(2):330-338. doi: 10.1007/s00415-018-9134-y. Epub 2018 Dec 1.


Simulation and Experimental Characterization of Lateral Imaging Resolution of Ultrasound Systems and Assessment of System Suitability for Acoustic Optic Nerve Sheath Diameter Measurement.

Lochner P, Behnke S, Fassbender K, Andrejewski A, Knodel S, Siniscalchi A, Jenderka KV, Lemor R.

J Neuroimaging. 2019 Jan;29(1):34-41. doi: 10.1111/jon.12578. Epub 2018 Nov 20.


B-Mode Transorbital Ultrasonography for the Diagnosis of Idiopathic Intracranial Hypertension: A Systematic Review and Meta-Analysis.

Lochner P, Fassbender K, Knodel S, Andrejewski A, Lesmeister M, Wagenpfeil G, Nardone R, Brigo F.

Ultraschall Med. 2019 Apr;40(2):247-252. doi: 10.1055/a-0719-4903. Epub 2018 Oct 22.


Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain.

Ma Q, Ries M, Decker Y, Müller A, Riner C, Bücker A, Fassbender K, Detmar M, Proulx ST.

Acta Neuropathol. 2019 Jan;137(1):151-165. doi: 10.1007/s00401-018-1916-x. Epub 2018 Oct 10.


A punch in the gut - Intestinal inflammation links environmental factors to neurodegeneration in Parkinson's disease.

Becker A, Faßbender K, Oertel WH, Unger MM.

Parkinsonism Relat Disord. 2019 Mar;60:43-45. doi: 10.1016/j.parkreldis.2018.09.032. Epub 2018 Sep 29.


Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase.

Oeckl P, Weydt P, Steinacker P, Anderl-Straub S, Nordin F, Volk AE, Diehl-Schmid J, Andersen PM, Kornhuber J, Danek A, Fassbender K, Fliessbach K; German Consortium for Frontotemporal Lobar Degeneration, Jahn H, Lauer M, Müller K, Knehr A, Prudlo J, Schneider A, Thal DR, Yilmazer-Hanke D, Weishaupt JH, Ludolph AC, Otto M.

J Neurol Neurosurg Psychiatry. 2019 Jan;90(1):4-10. doi: 10.1136/jnnp-2018-318868. Epub 2018 Sep 17.


Serum neurofilament light chain in behavioral variant frontotemporal dementia.

Steinacker P, Anderl-Straub S, Diehl-Schmid J, Semler E, Uttner I, von Arnim CAF, Barthel H, Danek A, Fassbender K, Fliessbach K, Foerstl H, Grimmer T, Huppertz HJ, Jahn H, Kassubek J, Kornhuber J, Landwehrmeyer B, Lauer M, Maler JM, Mayer B, Oeckl P, Prudlo J, Schneider A, Volk AE, Wiltfang J, Schroeter ML, Ludolph AC, Otto M; FTLDc study group.

Neurology. 2018 Oct 9;91(15):e1390-e1401. doi: 10.1212/WNL.0000000000006318. Epub 2018 Sep 12.


Mobile Stroke Units - Cost-Effective or Just an Expensive Hype?

Walter S, Grunwald IQ, Helwig SA, Ragoschke-Schumm A, Kettner M, Fousse M, Lesmeister M, Fassbender K.

Curr Atheroscler Rep. 2018 Aug 29;20(10):49. doi: 10.1007/s11883-018-0751-9. Review.


Air-Mobile Stroke Unit for access to stroke treatment in rural regions.

Walter S, Zhao H, Easton D, Bil C, Sauer J, Liu Y, Lesmeister M, Grunwald IQ, Donnan GA, Davis SM, Fassbender K.

Int J Stroke. 2018 Aug;13(6):568-575. doi: 10.1177/1747493018784450. Review.


Ginkgo biloba Extract EGb 761 and Its Specific Components Elicit Protective Protein Clearance Through the Autophagy-Lysosomal Pathway in Tau-Transgenic Mice and Cultured Neurons.

Qin Y, Zhang Y, Tomic I, Hao W, Menger MD, Liu C, Fassbender K, Liu Y.

J Alzheimers Dis. 2018;65(1):243-263. doi: 10.3233/JAD-180426.


Hyperacute stroke management is coming … one Mississippi, two Mississippi.

Fassbender K, Sheth KN.

Neurology. 2018 Aug 7;91(6):245-246. doi: 10.1212/WNL.0000000000005934. Epub 2018 Jul 11. No abstract available.


Mobile stroke unit use for prehospital stroke treatment-an update.

Walter S, Ragoschke-Schumm A, Lesmeister M, Helwig SA, Kettner M, Grunwald IQ, Fassbender K.

Radiologe. 2018 Nov;58(Suppl 1):24-28. doi: 10.1007/s00117-018-0408-2.


MIBG scintigraphy of the major salivary glands in multiple system atrophy.

Soboll L, Leppert D, Dillmann U, Schaefer-Schuler A, Fassbender K, Ezziddin S, Spiegel J.

Parkinsonism Relat Disord. 2018 Aug;53:112-114. doi: 10.1016/j.parkreldis.2018.04.034. Epub 2018 May 4.


Specific serum and CSF microRNA profiles distinguish sporadic behavioural variant of frontotemporal dementia compared with Alzheimer patients and cognitively healthy controls.

Denk J, Oberhauser F, Kornhuber J, Wiltfang J, Fassbender K, Schroeter ML, Volk AE, Diehl-Schmid J, Prudlo J, Danek A, Landwehrmeyer B, Lauer M, Otto M, Jahn H; FTLDc study group.

PLoS One. 2018 May 10;13(5):e0197329. doi: 10.1371/journal.pone.0197329. eCollection 2018.


A language-based sum score for the course and therapeutic intervention in primary progressive aphasia.

Semler E, Anderl-Straub S, Uttner I, Diehl-Schmid J, Danek A, Einsiedler B, Fassbender K, Fliessbach K, Huppertz HJ, Jahn H, Kornhuber J, Landwehrmeyer B, Lauer M, Muche R, Prudlo J, Schneider A, Schroeter ML, Ludolph AC, Otto M; FTLD consortium.

Alzheimers Res Ther. 2018 Apr 25;10(1):41. doi: 10.1186/s13195-018-0345-3.


Association of Schizotypy With Dimensions of Cognitive Control: A Meta-Analysis.

Steffens M, Meyhöfer I, Fassbender K, Ettinger U, Kambeitz J.

Schizophr Bull. 2018 Oct 15;44(suppl_2):S512-S524. doi: 10.1093/schbul/sby030.


Assay for improved detection of antigen-specific immune cells from extrasanguinous fluids.

Schub D, Fousse M, Elsäßer J, Faßbender K, Sester U, Schmidt T, Sester M.

Eur J Immunol. 2018 Aug;48(8):1412-1414. doi: 10.1002/eji.201847490. Epub 2018 Apr 23.


Fecal markers of intestinal inflammation and intestinal permeability are elevated in Parkinson's disease.

Schwiertz A, Spiegel J, Dillmann U, Grundmann D, Bürmann J, Faßbender K, Schäfer KH, Unger MM.

Parkinsonism Relat Disord. 2018 May;50:104-107. doi: 10.1016/j.parkreldis.2018.02.022. Epub 2018 Feb 12.


A Modified Reading the Mind in the Eyes Test Predicts Behavioral Variant Frontotemporal Dementia Better Than Executive Function Tests.

Schroeter ML, Pawelke S, Bisenius S, Kynast J, Schuemberg K, Polyakova M, Anderl-Straub S, Danek A, Fassbender K, Jahn H, Jessen F, Kornhuber J, Lauer M, Prudlo J, Schneider A, Uttner I, Thöne-Otto A, Otto M, Diehl-Schmid J.

Front Aging Neurosci. 2018 Jan 30;10:11. doi: 10.3389/fnagi.2018.00011. eCollection 2018.


Author response: Standard operating procedures improve acute neurologic care in a sub-Saharan African setting.

Fassbender K, Helwig SA, Jaiteh LES, Nyan O.

Neurology. 2018 Jan 9;90(2):100. doi: 10.1212/WNL.0000000000004790. No abstract available.


Consensus Development Conference: Promoting Access to Quality Palliative Care in Canada.

Fassbender K.

J Palliat Med. 2018 Jan;21(S1):S1-S8. doi: 10.1089/jpm.2017.0453.


Rapid Review and Synthesis of the Palliative Care Matters Scientific Evidence.

Sims M, Fassbender K.

J Palliat Med. 2018 Jan;21(S1):S15-S19. doi: 10.1089/jpm.2017.0389.


Evaluating Public Engagement for a Consensus Development Conference.

Chan M, Fassbender K.

J Palliat Med. 2018 Jan;21(S1):S20-S26. doi: 10.1089/jpm.2017.0390.


Analysis of the vasculature by immunohistochemistry in paraffin-embedded brains.

Decker Y, Müller A, Németh E, Schulz-Schaeffer WJ, Fatar M, Menger MD, Liu Y, Fassbender K.

Brain Struct Funct. 2018 Mar;223(2):1001-1015. doi: 10.1007/s00429-017-1595-8. Epub 2017 Dec 19.


Ocular ultrasound for monitoring pseudotumor cerebri syndrome.

Lochner P, Fassbender K, Lesmeister M, Nardone R, Orioli A, Brigo F, Stolz E.

J Neurol. 2018 Feb;265(2):356-361. doi: 10.1007/s00415-017-8699-1. Epub 2017 Dec 14.


Behaviors in Advance Care Planning and ACtions Survey (BACPACS): development and validation part 1.

Kassam A, Douglas ML, Simon J, Cunningham S, Fassbender K, Shaw M, Davison SN.

BMC Palliat Care. 2017 Nov 22;16(1):56. doi: 10.1186/s12904-017-0236-6.


Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression.

Steinacker P, Verde F, Fang L, Feneberg E, Oeckl P, Roeber S, Anderl-Straub S, Danek A, Diehl-Schmid J, Fassbender K, Fliessbach K, Foerstl H, Giese A, Jahn H, Kassubek J, Kornhuber J, Landwehrmeyer GB, Lauer M, Pinkhardt EH, Prudlo J, Rosenbohm A, Schneider A, Schroeter ML, Tumani H, von Arnim CAF, Weishaupt J, Weydt P, Ludolph AC, Yilmazer Hanke D, Otto M; FTLDc study group.

J Neurol Neurosurg Psychiatry. 2018 Mar;89(3):239-247. doi: 10.1136/jnnp-2017-317138. Epub 2017 Nov 15.


Blockade of Experimental Multiple Sclerosis by Inhibition of the Acid Sphingomyelinase/Ceramide System.

Becker KA, Halmer R, Davies L, Henry BD, Ziobro-Henry R, Decker Y, Liu Y, Gulbins E, Fassbender K, Walter S.

Neurosignals. 2017;25(1):88-97. doi: 10.1159/000484621. Epub 2017 Nov 6.


Prehospital Computed Tomography Angiography in Acute Stroke Management.

Kettner M, Helwig SA, Ragoschke-Schumm A, Schwindling L, Roumia S, Keller I, Martens D, Kulikovski J, Manitz M, Lesmeister M, Walter S, Grunwald IQ, Schlechtriemen T, Reith W, Fassbender K.

Cerebrovasc Dis. 2017;44(5-6):338-343. doi: 10.1159/000484097. Epub 2017 Oct 31.


Longitudinal Assessment of Transorbital Sonography, Visual Acuity, and Biomarkers for Inflammation and Axonal Injury in Optic Neuritis.

Lochner P, Cantello R, Fassbender K, Lesmeister M, Nardone R, Siniscalchi A, Clemente N, Naldi A, Coppo L, Brigo F, Comi C.

Dis Markers. 2017;2017:5434310. doi: 10.1155/2017/5434310. Epub 2017 Sep 11.


Regulation of Arthritis Severity by the Acid Sphingomyelinase.

Beckmann N, Becker KA, Walter S, Becker JU, Kramer M, Hessler G, Weber S, Göthert JR, Fassbender K, Gulbins E, Carpinteiro A.

Cell Physiol Biochem. 2017;43(4):1460-1471. doi: 10.1159/000481968. Epub 2017 Oct 16.


The PRE-hospital Stroke Treatment Organization.

Audebert H, Fassbender K, Hussain MS, Ebinger M, Turc G, Uchino K, Davis S, Alexandrov A, Grotta J; PRESTO Group.

Int J Stroke. 2017 Dec;12(9):932-940. doi: 10.1177/1747493017729268. Epub 2017 Sep 5. Review.


CTLA-4-expression on VZV-specific T cells in CSF and blood is specifically increased in patients with VZV related central nervous system infections.

Schub D, Fousse M, Faßbender K, Gärtner BC, Sester U, Sester M, Schmidt T.

Eur J Immunol. 2018 Jan;48(1):151-160. doi: 10.1002/eji.201747079. Epub 2017 Sep 14.

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