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Items: 1 to 50 of 157

1.

AAV-delivered eCD4-Ig protects rhesus macaques from high-dose SIVmac239 challenges.

Gardner MR, Fellinger CH, Kattenhorn LM, Davis-Gardner ME, Weber JA, Alfant B, Zhou AS, Prasad NR, Kondur HR, Newton WA, Weisgrau KL, Rakasz EG, Lifson JD, Gao G, Schultz-Darken N, Farzan M.

Sci Transl Med. 2019 Jul 24;11(502). pii: eaau5409. doi: 10.1126/scitranslmed.aau5409.

PMID:
31341061
2.

Zika Virus-Immune Plasmas from Symptomatic and Asymptomatic Individuals Enhance Zika Pathogenesis in Adult and Pregnant Mice.

Shim BS, Kwon YC, Ricciardi MJ, Stone M, Otsuka Y, Berri F, Kwal JM, Magnani DM, Jackson CB, Richard AS, Norris P, Busch M, Curry CL, Farzan M, Watkins D, Choe H.

MBio. 2019 Jul 2;10(4). pii: e00758-19. doi: 10.1128/mBio.00758-19.

3.

Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity.

Xiao Y, Muhuri M, Li S, Qin W, Xu G, Luo L, Li J, Letizia AJ, Wang SK, Chan YK, Wang C, Fuchs SP, Wang D, Su Q, Nahid MA, Church GM, Farzan M, Yang L, Wei Y, Desrosiers RC, Mueller C, Tai PW, Gao G.

JCI Insight. 2019 May 21;5. pii: 99052. doi: 10.1172/jci.insight.99052.

4.

eCD4-Ig Limits HIV-1 Escape More Effectively than CD4-Ig or a Broadly Neutralizing Antibody.

Fellinger CH, Gardner MR, Weber JA, Alfant B, Zhou AS, Farzan M.

J Virol. 2019 Jun 28;93(14). pii: e00443-19. doi: 10.1128/JVI.00443-19. Print 2019 Jul 15.

PMID:
31068428
5.

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET.

Lu M, Ma X, Castillo-Menendez LR, Gorman J, Alsahafi N, Ermel U, Terry DS, Chambers M, Peng D, Zhang B, Zhou T, Reichard N, Wang K, Grover JR, Carman BP, Gardner MR, Nikić-Spiegel I, Sugawara A, Arthos J, Lemke EA, Smith AB 3rd, Farzan M, Abrams C, Munro JB, McDermott AB, Finzi A, Kwong PD, Blanchard SC, Sodroski JG, Mothes W.

Nature. 2019 Apr;568(7752):415-419. doi: 10.1038/s41586-019-1101-y. Epub 2019 Apr 10.

6.

Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies.

Gardner MR, Fetzer I, Kattenhorn LM, Davis-Gardner ME, Zhou AS, Alfant B, Weber JA, Kondur HR, Martinez-Navio JM, Fuchs SP, Desrosiers RC, Gao G, Lifson JD, Farzan M.

Mol Ther. 2019 Mar 6;27(3):650-660. doi: 10.1016/j.ymthe.2019.01.004. Epub 2019 Jan 12.

7.

Loading of Porous Functionalized Calcium Carbonate Microparticles: Distribution Analysis with Focused Ion Beam Electron Microscopy and Mercury Porosimetry.

Farzan M, Roth R, Québatte G, Schoelkopf J, Huwyler J, Puchkov M.

Pharmaceutics. 2019 Jan 15;11(1). pii: E32. doi: 10.3390/pharmaceutics11010032.

8.

A Coreceptor-Mimetic Peptide Enhances the Potency of V3-Glycan Antibodies.

Fetzer I, Davis-Gardner ME, Gardner MR, Alfant B, Weber JA, Prasad NR, Zhou AS, Farzan M.

J Virol. 2019 Feb 19;93(5). pii: e01653-18. doi: 10.1128/JVI.01653-18. Print 2019 Mar 1.

9.

HIV-1 inhibitory properties of eCD4-Igmim2 determined using an Env-mediated membrane fusion assay.

Yang E, Gardner MR, Zhou AS, Farzan M, Arvin AM, Oliver SL.

PLoS One. 2018 Oct 25;13(10):e0206365. doi: 10.1371/journal.pone.0206365. eCollection 2018.

10.

Diverse pathways of escape from all well-characterized VRC01-class broadly neutralizing HIV-1 antibodies.

Otsuka Y, Schmitt K, Quinlan BD, Gardner MR, Alfant B, Reich A, Farzan M, Choe H.

PLoS Pathog. 2018 Aug 20;14(8):e1007238. doi: 10.1371/journal.ppat.1007238. eCollection 2018 Aug.

11.

eCD4-Ig Variants That More Potently Neutralize HIV-1.

Fetzer I, Gardner MR, Davis-Gardner ME, Prasad NR, Alfant B, Weber JA, Farzan M.

J Virol. 2018 May 29;92(12). pii: e02011-17. doi: 10.1128/JVI.02011-17. Print 2018 Jun 15.

12.

Conditional Regulation of Gene Expression by Ligand-Induced Occlusion of a MicroRNA Target Sequence.

Mou H, Zhong G, Gardner MR, Wang H, Wang YW, Cheng D, Farzan M.

Mol Ther. 2018 May 2;26(5):1277-1286. doi: 10.1016/j.ymthe.2018.02.021. Epub 2018 Feb 27.

13.

eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients.

Davis-Gardner ME, Gardner MR, Alfant B, Farzan M.

PLoS Pathog. 2017 Dec 18;13(12):e1006786. doi: 10.1371/journal.ppat.1006786. eCollection 2017 Dec.

14.

Severe rigid Scheuermann kyphosis in adult patients; correction with posterior-only approach.

Mirzashahi B, Chehrassan M, Arfa A, Farzan M.

Musculoskelet Surg. 2018 Dec;102(3):257-260. doi: 10.1007/s12306-017-0526-4. Epub 2017 Nov 17.

PMID:
29150740
15.

Simian Immunodeficiency Virus SIVmac239, but Not SIVmac316, Binds and Utilizes Human CD4 More Efficiently than Rhesus CD4.

Fellinger CH, Gardner MR, Bailey CC, Farzan M.

J Virol. 2017 Aug 24;91(18). pii: e00847-17. doi: 10.1128/JVI.00847-17. Print 2017 Sep 15.

16.

Ponseti Casting Method in Idiopathic Congenital Clubfoot and Its Correlation with Radiographic Features Abstract.

Baghdadi T, Bagheri N, Najafi A, Mansouri P, Farzan M.

Arch Bone Jt Surg. 2017 May;5(3):168-173.

17.

Cpf1 proteins excise CRISPR RNAs from mRNA transcripts in mammalian cells.

Zhong G, Wang H, Li Y, Tran MH, Farzan M.

Nat Chem Biol. 2017 Aug;13(8):839-841. doi: 10.1038/nchembio.2410. Epub 2017 Jun 19.

18.

Poly (ethylene-co-vinyl alcohol)-based polymeric thermo-responsive nanocarriers for controlled delivery of epirubicin to hepatocellular carcinoma.

Hassanzadeh F, Farzan M, Varshosaz J, Khodarahmi GA, Maaleki S, Rostami M.

Res Pharm Sci. 2017 Apr;12(2):107-118. doi: 10.4103/1735-5362.202449.

19.

Engineering antibody-like inhibitors to prevent and treat HIV-1 infection.

Gardner MR, Farzan M.

Curr Opin HIV AIDS. 2017 May;12(3):294-301. doi: 10.1097/COH.0000000000000367. Review.

20.

Rational design of aptazyme riboswitches for efficient control of gene expression in mammalian cells.

Zhong G, Wang H, Bailey CC, Gao G, Farzan M.

Elife. 2016 Nov 2;5. pii: e18858. doi: 10.7554/eLife.18858.

21.

Management of postoperative pain after Lumbar surgery-pregabalin for one day and 14 days-a randomized, triple-blinded, placebo-controlled study.

Zarei M, Najafi A, Mansouri P, Sadeghi-Yazdankhah S, Saberi H, Moradi M, Farzan M.

Clin Neurol Neurosurg. 2016 Dec;151:37-42. doi: 10.1016/j.clineuro.2016.10.007. Epub 2016 Oct 17.

PMID:
27764706
22.

The Interferon-Stimulated Gene IFITM3 Restricts Infection and Pathogenesis of Arthritogenic and Encephalitic Alphaviruses.

Poddar S, Hyde JL, Gorman MJ, Farzan M, Diamond MS.

J Virol. 2016 Sep 12;90(19):8780-94. doi: 10.1128/JVI.00655-16. Print 2016 Oct 1.

23.

The Interferon-Stimulated Gene Ifitm3 Restricts West Nile Virus Infection and Pathogenesis.

Gorman MJ, Poddar S, Farzan M, Diamond MS.

J Virol. 2016 Aug 26;90(18):8212-25. doi: 10.1128/JVI.00581-16. Print 2016 Sep 15.

24.

CD4-Induced Antibodies Promote Association of the HIV-1 Envelope Glycoprotein with CD4-Binding Site Antibodies.

Gardner MR, Fellinger CH, Prasad NR, Zhou AS, Kondur HR, Joshi VR, Quinlan BD, Farzan M.

J Virol. 2016 Aug 12;90(17):7822-32. doi: 10.1128/JVI.00803-16. Print 2016 Sep 1.

25.

Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques.

Li H, Wang S, Kong R, Ding W, Lee FH, Parker Z, Kim E, Learn GH, Hahn P, Policicchio B, Brocca-Cofano E, Deleage C, Hao X, Chuang GY, Gorman J, Gardner M, Lewis MG, Hatziioannou T, Santra S, Apetrei C, Pandrea I, Alam SM, Liao HX, Shen X, Tomaras GD, Farzan M, Chertova E, Keele BF, Estes JD, Lifson JD, Doms RW, Montefiori DC, Haynes BF, Sodroski JG, Kwong PD, Hahn BH, Shaw GM.

Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):E3413-22. doi: 10.1073/pnas.1606636113. Epub 2016 May 31.

26.

Neglected Alkaptonuric Patient Presenting with Steppage Gait.

Mirzashahi B, Tafakhori A, Najafi A, Farzan M.

Arch Bone Jt Surg. 2016 Apr;4(2):188-91.

27.

Nanoparticles for targeted delivery of therapeutics and small interfering RNAs in hepatocellular carcinoma.

Varshosaz J, Farzan M.

World J Gastroenterol. 2015 Nov 14;21(42):12022-41. doi: 10.3748/wjg.v21.i42.12022. Review.

28.

Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile viruses.

Richard AS, Zhang A, Park SJ, Farzan M, Zong M, Choe H.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14682-7. doi: 10.1073/pnas.1508095112. Epub 2015 Nov 2.

29.

Total Knee Arthroplasty: Does the Tibial Medial Side Defect Affect Outcome?

Vahedian-Ardakani M, Mortazavi SM, Farzan M.

Acta Med Iran. 2015 Aug;53(8):462-5.

30.

Mechanism for Selective Synaptic Wiring of Rod Photoreceptors into the Retinal Circuitry and Its Role in Vision.

Cao Y, Sarria I, Fehlhaber KE, Kamasawa N, Orlandi C, James KN, Hazen JL, Gardner MR, Farzan M, Lee A, Baker S, Baldwin K, Sampath AP, Martemyanov KA.

Neuron. 2015 Sep 23;87(6):1248-1260. doi: 10.1016/j.neuron.2015.09.002.

31.

The Triggering Receptor Expressed on Myeloid Cells 2 Binds Apolipoprotein E.

Bailey CC, DeVaux LB, Farzan M.

J Biol Chem. 2015 Oct 23;290(43):26033-42. doi: 10.1074/jbc.M115.677286. Epub 2015 Sep 15.

32.

Vascularized posterior interosseous pedicled bone grafting for infected forearm nonunion.

Kamrani RS, Farhoud A, Nabian MH, Zanjani LO, Farzan M.

J Hand Surg Eur Vol. 2016 May;41(4):441-7. doi: 10.1177/1753193415601041. Epub 2015 Aug 25.

PMID:
26307139
33.

Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated Cytotoxicity.

von Bredow B, Arias JF, Heyer LN, Gardner MR, Farzan M, Rakasz EG, Evans DT.

J Virol. 2015 Oct;89(20):10648-55. doi: 10.1128/JVI.01911-15. Epub 2015 Aug 12.

34.

Combining Concentrated Autologous Bone Marrow Stem Cells Injection With Core Decompression Improves Outcome for Patients with Early-Stage Osteonecrosis of the Femoral Head: A Comparative Study.

Tabatabaee RM, Saberi S, Parvizi J, Mortazavi SM, Farzan M.

J Arthroplasty. 2015 Sep;30(9 Suppl):11-5. doi: 10.1016/j.arth.2015.06.022. Epub 2015 Jun 19.

PMID:
26143238
35.

Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas.

Barbian HJ, Decker JM, Bibollet-Ruche F, Galimidi RP, West AP Jr, Learn GH, Parrish NF, Iyer SS, Li Y, Pace CS, Song R, Huang Y, Denny TN, Mouquet H, Martin L, Acharya P, Zhang B, Kwong PD, Mascola JR, Verrips CT, Strokappe NM, Rutten L, McCoy LE, Weiss RA, Brown CS, Jackson R, Silvestri G, Connors M, Burton DR, Shaw GM, Nussenzweig MC, Bjorkman PJ, Ho DD, Farzan M, Hahn BH.

MBio. 2015 Apr 21;6(2). pii: e00296-15. doi: 10.1128/mBio.00296-15.

36.

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.

Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES Jr, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, Quinlan BD, Yao AY, Mouquet H, Gorman J, Zhang B, Poignard P, Nussenzweig MC, Burton DR, Kwong PD, Piatak M Jr, Lifson JD, Gao G, Desrosiers RC, Evans DT, Hahn BH, Ploss A, Cannon PM, Seaman MS, Farzan M.

Nature. 2015 Mar 5;519(7541):87-91. doi: 10.1038/nature14264. Epub 2015 Feb 18.

37.

IFITM-Family Proteins: The Cell's First Line of Antiviral Defense.

Bailey CC, Zhong G, Huang IC, Farzan M.

Annu Rev Virol. 2014 Nov 1;1:261-283.

38.

IFITM3 polymorphism rs12252-C restricts influenza A viruses.

Williams DE, Wu WL, Grotefend CR, Radic V, Chung C, Chung YH, Farzan M, Huang IC.

PLoS One. 2014 Oct 14;9(10):e110096. doi: 10.1371/journal.pone.0110096. eCollection 2014.

39.

Osseous tumours of the hand: a review of 99 cases in 20 years.

Farzan M, Ahangar P, Mazoochy H, Ardakani MV.

Arch Bone Jt Surg. 2013 Dec;1(2):68-73. Epub 2013 Dec 15.

40.

The antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus.

Warren CJ, Griffin LM, Little AS, Huang IC, Farzan M, Pyeon D.

PLoS One. 2014 May 14;9(5):e96579. doi: 10.1371/journal.pone.0096579. eCollection 2014.

41.

UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs.

Pirooz SD, He S, Zhang T, Zhang X, Zhao Z, Oh S, O'Connell D, Khalilzadeh P, Amini-Bavil-Olyaee S, Farzan M, Liang C.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2716-21. doi: 10.1073/pnas.1320629111. Epub 2014 Feb 3.

42.

A double-mimetic peptide efficiently neutralizes HIV-1 by bridging the CD4- and coreceptor-binding sites of gp120.

Quinlan BD, Joshi VR, Gardner MR, Ebrahimi KH, Farzan M.

J Virol. 2014 Mar;88(6):3353-8. doi: 10.1128/JVI.03800-13. Epub 2014 Jan 3.

43.

Interferon-induced transmembrane protein 3 is a type II transmembrane protein.

Bailey CC, Kondur HR, Huang IC, Farzan M.

J Biol Chem. 2013 Nov 8;288(45):32184-93. doi: 10.1074/jbc.M113.514356. Epub 2013 Sep 25.

44.

Dual host-virus arms races shape an essential housekeeping protein.

Demogines A, Abraham J, Choe H, Farzan M, Sawyer SL.

PLoS Biol. 2013;11(5):e1001571. doi: 10.1371/journal.pbio.1001571. Epub 2013 May 28.

45.

IFITM-2 and IFITM-3 but not IFITM-1 restrict Rift Valley fever virus.

Mudhasani R, Tran JP, Retterer C, Radoshitzky SR, Kota KP, Altamura LA, Smith JM, Packard BZ, Kuhn JH, Costantino J, Garrison AR, Schmaljohn CS, Huang IC, Farzan M, Bavari S.

J Virol. 2013 Aug;87(15):8451-64. doi: 10.1128/JVI.03382-12. Epub 2013 May 29.

46.

Direct expression and validation of phage-selected peptide variants in mammalian cells.

Quinlan BD, Gardner MR, Joshi VR, Chiang JJ, Farzan M.

J Biol Chem. 2013 Jun 28;288(26):18803-10. doi: 10.1074/jbc.M113.452839. Epub 2013 May 10.

47.

The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry.

Amini-Bavil-Olyaee S, Choi YJ, Lee JH, Shi M, Huang IC, Farzan M, Jung JU.

Cell Host Microbe. 2013 Apr 17;13(4):452-64. doi: 10.1016/j.chom.2013.03.006. Erratum in: Cell Host Microbe. 2013 Nov 13;14(5):600-1.

48.

Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors.

Brudner M, Karpel M, Lear C, Chen L, Yantosca LM, Scully C, Sarraju A, Sokolovska A, Zariffard MR, Eisen DP, Mungall BA, Kotton DN, Omari A, Huang IC, Farzan M, Takahashi K, Stuart L, Stahl GL, Ezekowitz AB, Spear GT, Olinger GG, Schmidt EV, Michelow IC.

PLoS One. 2013;8(4):e60838. doi: 10.1371/journal.pone.0060838. Epub 2013 Apr 2.

49.

TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine.

Jemielity S, Wang JJ, Chan YK, Ahmed AA, Li W, Monahan S, Bu X, Farzan M, Freeman GJ, Umetsu DT, Dekruyff RH, Choe H.

PLoS Pathog. 2013 Mar;9(3):e1003232. doi: 10.1371/journal.ppat.1003232. Epub 2013 Mar 28.

50.

The broad-spectrum antiviral functions of IFIT and IFITM proteins.

Diamond MS, Farzan M.

Nat Rev Immunol. 2013 Jan;13(1):46-57. doi: 10.1038/nri3344. Epub 2012 Dec 14. Review.

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