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Items: 1 to 50 of 132


Computational modeling of retinal hypoxia and photoreceptor degeneration in patients with age-related macular degeneration.

McHugh KJ, Li D, Wang JC, Kwark L, Loo J, Macha V, Farsiu S, Kim LA, Saint-Geniez M.

PLoS One. 2019 Jun 11;14(6):e0216215. doi: 10.1371/journal.pone.0216215. eCollection 2019.


Open-source, machine and deep learning-based automated algorithm for gestational age estimation through smartphone lens imaging.

Desai AD, Peng C, Fang L, Mukherjee D, Yeung A, Jaffe SJ, Griffin JB, Farsiu S.

Biomed Opt Express. 2018 Nov 7;9(12):6038-6052. doi: 10.1364/BOE.9.006038. eCollection 2018 Dec 1.


Linking OCT, Angiographic, and Photographic Lesion Components in Neovascular Age-Related Macular Degeneration.

Toth CA, Tai V, Chiu SJ, Winter K, Sevilla MB, Daniel E, Grunwald JE, Jaffe GJ, Martin DF, Ying GS, Pistilli M, Farsiu S, Maguire MG; Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) Research Group.

Ophthalmol Retina. 2018 May;2(5):481-493. doi: 10.1016/j.oret.2017.09.016. Epub 2017 Nov 28.


Distribution of OCT Features within Areas of Macular Atrophy or Scar after 2 Years of Anti-VEGF Treatment for Neovascular AMD in CATT.

Toth CA, Tai V, Pistilli M, Chiu SJ, Winter KP, Daniel E, Grunwald JE, Jaffe GJ, Martin DF, Ying GS, Farsiu S, Maguire MG; Comparison of Age-related Macular Degeneration Treatments Trials Research Group.

Ophthalmol Retina. 2019 Apr;3(4):316-325. doi: 10.1016/j.oret.2018.11.011. Epub 2018 Dec 3.


Fast and robust active neuron segmentation in two-photon calcium imaging using spatiotemporal deep learning.

Soltanian-Zadeh S, Sahingur K, Blau S, Gong Y, Farsiu S.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8554-8563. doi: 10.1073/pnas.1812995116. Epub 2019 Apr 11.


Vascular Response to Sildenafil Citrate in Aging and Age-Related Macular Degeneration.

Yiu G, Vuong VS, Tran S, Migacz J, Cunefare D, Farsiu S, Khandelwal N, Agrawal R, Cheung CMG.

Sci Rep. 2019 Mar 25;9(1):5049. doi: 10.1038/s41598-019-41509-2.


Estimation of Gestational Age via Image Analysis of Anterior Lens Capsule Vascularity in Preterm Infants: A Pilot Study.

Patel M, Mukherjee D, Farsiu S, Munoz B, Blood AB, Wilson CG, Griffin JB.

Front Pediatr. 2019 Feb 20;7:43. doi: 10.3389/fped.2019.00043. eCollection 2019.


In vivo measurement of trabecular meshwork stiffness in a corticosteroid-induced ocular hypertensive mouse model.

Li G, Lee C, Agrahari V, Wang K, Navarro I, Sherwood JM, Crews K, Farsiu S, Gonzalez P, Lin CW, Mitra AK, Ethier CR, Stamer WD.

Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1714-1722. doi: 10.1073/pnas.1814889116. Epub 2019 Jan 16.


Deep learning based detection of cone photoreceptors with multimodal adaptive optics scanning light ophthalmoscope images of achromatopsia.

Cunefare D, Langlo CS, Patterson EJ, Blau S, Dubra A, Carroll J, Farsiu S.

Biomed Opt Express. 2018 Jul 18;9(8):3740-3756. doi: 10.1364/BOE.9.003740. eCollection 2018 Aug 1.


Effects of aging and environmental tobacco smoke exposure on ocular and plasma circulatory microRNAs in the Rhesus macaque.

Smit-McBride Z, Nguyen J, Elliott GW, Wang Z, McBride RA, Nguyen AT, Oltjen SL, Yiu G, Thomasy SM, Pinkerton KE, Lee ES, Cunefare D, Farsiu S, Morse LS.

Mol Vis. 2018 Sep 24;24:633-646. eCollection 2018.


Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2: A Randomized Clinical Trial.

Chew EY, Clemons TE, Jaffe GJ, Johnson CA, Farsiu S, Lad EM, Guymer R, Rosenfeld P, Hubschman JP, Constable I, Wiley H, Singerman LJ, Gillies M, Comer G, Blodi B, Eliott D, Yan J, Bird A, Friedlander M; Macular Telangiectasia Type 2-Phase 2 CNTF Research Group.

Ophthalmology. 2019 Apr;126(4):540-549. doi: 10.1016/j.ophtha.2018.09.041. Epub 2018 Oct 4.


Real-time corneal segmentation and 3D needle tracking in intrasurgical OCT.

Keller B, Draelos M, Tang G, Farsiu S, Kuo AN, Hauser K, Izatt JA.

Biomed Opt Express. 2018 May 21;9(6):2716-2732. doi: 10.1364/BOE.9.002716. eCollection 2018 Jun 1.


Deep longitudinal transfer learning-based automatic segmentation of photoreceptor ellipsoid zone defects on optical coherence tomography images of macular telangiectasia type 2.

Loo J, Fang L, Cunefare D, Jaffe GJ, Farsiu S.

Biomed Opt Express. 2018 May 16;9(6):2681-2698. doi: 10.1364/BOE.9.002681. eCollection 2018 Jun 1.


Ocular amyloid imaging at the crossroad of Alzheimer's disease and age-related macular degeneration: implications for diagnosis and therapy.

Ong SS, Proia AD, Whitson HE, Farsiu S, Doraiswamy PM, Lad EM.

J Neurol. 2019 Jul;266(7):1566-1577. doi: 10.1007/s00415-018-9028-z. Epub 2018 Aug 28. Review.


Information-Theoretic Approach and Fundamental Limits of Resolving Two Closely Timed Neuronal Spikes in Mouse Brain Calcium Imaging.

Soltanian-Zadeh S, Gong Y, Farsiu S.

IEEE Trans Biomed Eng. 2018 Nov;65(11):2428-2439. doi: 10.1109/TBME.2018.2812078. Epub 2018 Mar 8.


Statistical Models of Signal and Noise and Fundamental Limits of Segmentation Accuracy in Retinal Optical Coherence Tomography.

Dubose TB, Cunefare D, Cole E, Milanfar P, Izatt JA, Farsiu S.

IEEE Trans Med Imaging. 2018 Sep;37(9):1978-1988. doi: 10.1109/TMI.2017.2772963. Epub 2017 Nov 13.


Demonstration of anatomical development of the human macula within the first 5 years of life using handheld OCT.

Alabduljalil T, Westall CA, Reginald A, Farsiu S, Chiu SJ, Arshavsky A, Toth CA, Lam WC.

Int Ophthalmol. 2018 Jun 23. doi: 10.1007/s10792-018-0966-3. [Epub ahead of print]



Willoughby AS, Vuong VS, Cunefare D, Farsiu S, Noronha G, Danis RP, Yiu G.

Am J Ophthalmol. 2018 May;189:178. doi: 10.1016/j.ajo.2018.03.002. Epub 2018 Mar 22. No abstract available.


Evaluation of inner retinal layers as biomarkers in mild cognitive impairment to moderate Alzheimer's disease.

Lad EM, Mukherjee D, Stinnett SS, Cousins SW, Potter GG, Burke JR, Farsiu S, Whitson HE.

PLoS One. 2018 Feb 8;13(2):e0192646. doi: 10.1371/journal.pone.0192646. eCollection 2018.


Comparison of chorioretinal layers in rhesus macaques using spectral-domain optical coherence tomography and high-resolution histological sections.

Yiu G, Wang Z, Munevar C, Tieu E, Shibata B, Wong B, Cunefare D, Farsiu S, Roberts J, Thomasy SM.

Exp Eye Res. 2018 Mar;168:69-76. doi: 10.1016/j.exer.2018.01.012. Epub 2018 Jan 17.


Novel Image-Based Analysis for Reduction of Clinician-Dependent Variability in Measurement of the Corneal Ulcer Size.

Patel TP, Prajna NV, Farsiu S, Valikodath NG, Niziol LM, Dudeja L, Kim KH, Woodward MA.

Cornea. 2018 Mar;37(3):331-339. doi: 10.1097/ICO.0000000000001488.


Choroidal Changes After Suprachoroidal Injection of Triamcinolone Acetonide in Eyes With Macular Edema Secondary to Retinal Vein Occlusion.

Willoughby AS, Vuong VS, Cunefare D, Farsiu S, Noronha G, Danis RP, Yiu G.

Am J Ophthalmol. 2018 Feb;186:144-151. doi: 10.1016/j.ajo.2017.11.020. Epub 2017 Dec 2.


In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques.

Yiu G, Tieu E, Munevar C, Wong B, Cunefare D, Farsiu S, Garzel L, Roberts J, Thomasy SM.

Sci Rep. 2017 Nov 3;7(1):15013. doi: 10.1038/s41598-017-14715-z.


Characterization of Long Working Distance Optical Coherence Tomography for Imaging of Pediatric Retinal Pathology.

Qian R, Carrasco-Zevallos OM, Mangalesh S, Sarin N, Vajzovic L, Farsiu S, Izatt JA, Toth CA.

Transl Vis Sci Technol. 2017 Oct 16;6(5):12. doi: 10.1167/tvst.6.5.12. eCollection 2017 Oct.


Macular Fluid Reduces Reproducibility of Choroidal Thickness Measurements on Enhanced Depth Optical Coherence Tomography.

Wong SS, Vuong VS, Cunefare D, Farsiu S, Moshiri A, Yiu G.

Am J Ophthalmol. 2017 Dec;184:108-114. doi: 10.1016/j.ajo.2017.10.005. Epub 2017 Oct 14.


Correlation Between Macular Integrity Assessment and Optical Coherence Tomography Imaging of Ellipsoid Zone in Macular Telangiectasia Type 2.

Mukherjee D, Lad EM, Vann RR, Jaffe SJ, Clemons TE, Friedlander M, Chew EY, Jaffe GJ, Farsiu S; MacTel Study Group.

Invest Ophthalmol Vis Sci. 2017 May 1;58(6):BIO291-BIO299. doi: 10.1167/iovs.17-21834.


Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope.

McNabb RP, Tian J, Farsiu S, Izatt JA, Lad EM, Kuo AN.

Biomed Opt Express. 2017 Aug 21;8(9):4152-4159. doi: 10.1364/BOE.8.004152. eCollection 2017 Sep 1.


Optical Coherence Tomography Predictors of Risk for Progression to Non-Neovascular Atrophic Age-Related Macular Degeneration.

Sleiman K, Veerappan M, Winter KP, McCall MN, Yiu G, Farsiu S, Chew EY, Clemons T, Toth CA; Age-Related Eye Disease Study 2 Ancillary Spectral Domain Optical Coherence Tomography Study Group.

Ophthalmology. 2017 Dec;124(12):1764-1777. doi: 10.1016/j.ophtha.2017.06.032. Epub 2017 Aug 26.


Using an Image Fusion Methodology to Improve Efficiency and Traceability of Posterior Pole Vessel Analysis by ROPtool.

Prakalapakorn SG, Vickers LA, Estrada R, Freedman SF, Tomasi C, Farsiu S, Wallace DK.

Open Ophthalmol J. 2017 Jun 29;11:143-151. doi: 10.2174/1874364101711010143. eCollection 2017.


Open source software for automatic detection of cone photoreceptors in adaptive optics ophthalmoscopy using convolutional neural networks.

Cunefare D, Fang L, Cooper RF, Dubra A, Carroll J, Farsiu S.

Sci Rep. 2017 Jul 26;7(1):6620. doi: 10.1038/s41598-017-07103-0.


Automatic segmentation of nine retinal layer boundaries in OCT images of non-exudative AMD patients using deep learning and graph search.

Fang L, Cunefare D, Wang C, Guymer RH, Li S, Farsiu S.

Biomed Opt Express. 2017 Apr 27;8(5):2732-2744. doi: 10.1364/BOE.8.002732. eCollection 2017 May 1.


A Quantitative Approach to Predict Differential Effects of Anti-VEGF Treatment on Diffuse and Focal Leakage in Patients with Diabetic Macular Edema: A Pilot Study.

Allingham MJ, Mukherjee D, Lally EB, Rabbani H, Mettu PS, Cousins SW, Farsiu S.

Transl Vis Sci Technol. 2017 Mar 21;6(2):7. doi: 10.1167/tvst.6.2.7. eCollection 2017 Mar.


Platform-Independent Cirrus and Spectralis Thickness Measurements in Eyes with Diabetic Macular Edema Using Fully Automated Software.

Willoughby AS, Chiu SJ, Silverman RK, Farsiu S, Bailey C, Wiley HE, Ferris FL 3rd, Jaffe GJ.

Transl Vis Sci Technol. 2017 Feb 7;6(1):9. doi: 10.1167/tvst.6.1.9. eCollection 2017 Feb.


Wide-field retinal optical coherence tomography with wavefront sensorless adaptive optics for enhanced imaging of targeted regions.

Polans J, Keller B, Carrasco-Zevallos OM, LaRocca F, Cole E, Whitson HE, Lad EM, Farsiu S, Izatt JA.

Biomed Opt Express. 2016 Dec 2;8(1):16-37. doi: 10.1364/BOE.8.000016. eCollection 2017 Jan 1.


Enhanced visualization of peripheral retinal vasculature with wavefront sensorless adaptive optics optical coherence tomography angiography in diabetic patients.

Polans J, Cunefare D, Cole E, Keller B, Mettu PS, Cousins SW, Allingham MJ, Izatt JA, Farsiu S.

Opt Lett. 2017 Jan 1;42(1):17-20. doi: 10.1364/OL.42.000017.


Segmentation guided registration of wide field-of-view retinal optical coherence tomography volumes.

Lezama J, Mukherjee D, McNabb RP, Sapiro G, Kuo AN, Farsiu S.

Biomed Opt Express. 2016 Nov 1;7(12):4827-4846. doi: 10.1364/BOE.7.004827. eCollection 2016 Dec 1.


Anatomy and spatial organization of Müller glia in mouse retina.

Wang J, O'Sullivan ML, Mukherjee D, Puñal VM, Farsiu S, Kay JN.

J Comp Neurol. 2017 Jun 1;525(8):1759-1777. doi: 10.1002/cne.24153. Epub 2017 Mar 7.


Understanding RPE Lipofuscin.

Smith RT, Farsiu S, Allingham M.

Invest Ophthalmol Vis Sci. 2016 Dec 1;57(15):6766. doi: 10.1167/iovs.16-21081. No abstract available.


Effect of Uveal Melanocytes on Choroidal Morphology in Rhesus Macaques and Humans on Enhanced-Depth Imaging Optical Coherence Tomography.

Yiu G, Vuong VS, Oltjen S, Cunefare D, Farsiu S, Garzel L, Roberts J, Thomasy SM.

Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5764-5771. doi: 10.1167/iovs.16-20070.


Validation of Macular Choroidal Thickness Measurements from Automated SD-OCT Image Segmentation.

Twa MD, Schulle KL, Chiu SJ, Farsiu S, Berntsen DA.

Optom Vis Sci. 2016 Nov;93(11):1387-1398.


Needle Depth and Big-Bubble Success in Deep Anterior Lamellar Keratoplasty: An Ex Vivo Microscope-Integrated OCT Study.

Pasricha ND, Shieh C, Carrasco-Zevallos OM, Keller B, Cunefare D, Mehta JS, Farsiu S, Izatt JA, Toth CA, Kuo AN.

Cornea. 2016 Nov;35(11):1471-1477.


Retinal nerve fiber layer thickness in amnestic mild cognitive impairment: Case-control study and meta-analysis.

Knoll B, Simonett J, Volpe NJ, Farsiu S, Ward M, Rademaker A, Weintraub S, Fawzi AA.

Alzheimers Dement (Amst). 2016 Aug 19;4:85-93. eCollection 2016.


Segmentation Based Sparse Reconstruction of Optical Coherence Tomography Images.

Fang L, Li S, Cunefare D, Farsiu S.

IEEE Trans Med Imaging. 2017 Feb;36(2):407-421. doi: 10.1109/TMI.2016.2611503. Epub 2016 Sep 20.


Live volumetric (4D) visualization and guidance of in vivo human ophthalmic surgery with intraoperative optical coherence tomography.

Carrasco-Zevallos OM, Keller B, Viehland C, Shen L, Waterman G, Todorich B, Shieh C, Hahn P, Farsiu S, Kuo AN, Toth CA, Izatt JA.

Sci Rep. 2016 Aug 19;6:31689. doi: 10.1038/srep31689.


Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images.

Keller B, Cunefare D, Grewal DS, Mahmoud TH, Izatt JA, Farsiu S.

J Biomed Opt. 2016 Jul 1;21(7):76015. doi: 10.1117/1.JBO.21.7.076015.


Analyzing spatial correlations in tissue using angle-resolved low coherence interferometry measurements guided by co-located optical coherence tomography.

Kim S, Heflin S, Kresty LA, Halling M, Perez LN, Ho D, Crose M, Brown W, Farsiu S, Arshavsky V, Wax A.

Biomed Opt Express. 2016 Mar 21;7(4):1400-14. doi: 10.1364/BOE.7.001400. eCollection 2016 Apr 1.


Longitudinal Associations Between Microstructural Changes and Microperimetry in the Early Stages of Age-Related Macular Degeneration.

Wu Z, Cunefare D, Chiu E, Luu CD, Ayton LN, Toth CA, Farsiu S, Guymer RH.

Invest Ophthalmol Vis Sci. 2016 Jul 1;57(8):3714-22. doi: 10.1167/iovs.15-18294.


Posterior Eye Shape Measurement With Retinal OCT Compared to MRI.

Kuo AN, Verkicharla PK, McNabb RP, Cheung CY, Hilal S, Farsiu S, Chen C, Wong TY, Ikram MK, Cheng CY, Young TL, Saw SM, Izatt JA.

Invest Ophthalmol Vis Sci. 2016 Jul 1;57(9):OCT196-203. doi: 10.1167/iovs.15-18886.


Impact of Microscope-Integrated OCT on Ophthalmology Resident Performance of Anterior Segment Surgical Maneuvers in Model Eyes.

Todorich B, Shieh C, DeSouza PJ, Carrasco-Zevallos OM, Cunefare DL, Stinnett SS, Izatt JA, Farsiu S, Mruthyunjaya P, Kuo AN, Toth CA.

Invest Ophthalmol Vis Sci. 2016 Jul 1;57(9):OCT146-53. doi: 10.1167/iovs.15-18818.


Macular sub-layer thinning and association with pulmonary function tests in Amyotrophic Lateral Sclerosis.

Simonett JM, Huang R, Siddique N, Farsiu S, Siddique T, Volpe NJ, Fawzi AA.

Sci Rep. 2016 Jul 7;6:29187. doi: 10.1038/srep29187.

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