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Daily Time of Radiation Treatment is Associated with Subsequent Oral Mucositis Severity during Radiotherapy in Head and Neck Cancer Patients.

Gu F, Farrugia MK, Duncan WD, Feng Y, Hutson AD, Schlecht NF, Repasky EA, Antoch MP, Miller A, Platek A, Platek ME, Iovoli AJ, Singh AK.

Cancer Epidemiol Biomarkers Prev. 2020 Feb 25. doi: 10.1158/1055-9965.EPI-19-0961. [Epub ahead of print]


Renal scarring is the most significant predictor of breakthrough febrile urinary tract infection in patients with simplex and duplex primary vesico-ureteral reflux.

Loukogeorgakis SP, Burnand K, MacDonald A, Wessely K, De Caluwe' D, Rahman N, Farrugia MK.

J Pediatr Urol. 2019 Dec 16. pii: S1477-5131(19)30422-X. doi: 10.1016/j.jpurol.2019.11.018. [Epub ahead of print]


The endoplasmic reticulum acetyltransferases ATase1/NAT8B and ATase2/NAT8 are differentially regulated to adjust engagement of the secretory pathway.

Rigby MJ, Ding Y, Farrugia MA, Feig M, Cortese GP, Mitchell H, Burger C, Puglielli L.

J Neurochem. 2020 Jan 16:e14958. doi: 10.1111/jnc.14958. [Epub ahead of print]


What to Do With Deauville 3 Interim Positron Emission Tomography/Computed Tomography Response in a Young Woman With Classic Unfavorable Hodgkin's Lymphoma: To Irradiate or Not to Irradiate?

Farrugia MK, Vargo JA.

Int J Radiat Oncol Biol Phys. 2020 Jan 1;106(1):13-14. doi: 10.1016/j.ijrobp.2018.02.162. No abstract available.


Analysis of Patients Diagnosed with Benign Paroxysmal Positional Vertigo and the Corresponding Incidence and Patterns of Electric Toothbrush Use.

Sayal NR, Cox EL, Foster N, Globerson M, Farrugia M.

Cureus. 2019 Sep 19;11(9):e5697. doi: 10.7759/cureus.5697.


Assessment of Coagulation by Thromboelastography During Ongoing Postpartum Hemorrhage: A Retrospective Cohort Analysis.

Rigouzzo A, Louvet N, Favier R, Ore MV, Piana F, Girault L, Farrugia M, Sabourdin N, Constant I.

Anesth Analg. 2020 Feb;130(2):416-425. doi: 10.1213/ANE.0000000000004422.


Brain Structural Features of Myotonic Dystrophy Type 1 and their Relationship with CTG Repeats.

van der Plas E, Hamilton MJ, Miller JN, Koscik TR, Long JD, Cumming S, Povilaikaite J, Farrugia ME, McLean J, Jampana R, Magnotta VA, Gutmann L, Monckton DG, Nopoulos PC.

J Neuromuscul Dis. 2019;6(3):321-332. doi: 10.3233/JND-190397.


The prevalence of faecal incontinence in myotonic dystrophy type 1.

Petty RKH, Eugenicos MP, Hamilton MJ, Farrugia ME, Robb Y, Ballantyne R, Gregory H, McWilliam C, Longman C.

Neuromuscul Disord. 2019 Jul;29(7):562-566. doi: 10.1016/j.nmd.2019.05.009. Epub 2019 Jun 7.


The road to gender equity in surgery is long

Tannenbaum E, Farrugia M.

Can J Surg. 2019 Jun 1;62(3):E4. No abstract available.


Infantile pemphigoid treated without oral corticosteroids.

Farrugia ME, Ball SL, Tidman MJ.

Clin Exp Dermatol. 2019 Oct;44(7):832-833. doi: 10.1111/ced.14004. Epub 2019 Jun 12. No abstract available.


Physician procedure volume and related adverse events after surgically induced abortion: a population-based cohort study.

Liu N, Vigod SN, Farrugia MM, Urquia ML, Ray JG.

CMAJ. 2019 May 13;191(19):E519-E528. doi: 10.1503/cmaj.181288. Epub 2019 May 12.


Guidelines for single fiber EMG.

Sanders DB, Arimura K, Cui L, Ertaş M, Farrugia ME, Gilchrist J, Kouyoumdjian JA, Padua L, Pitt M, Stålberg E.

Clin Neurophysiol. 2019 Aug;130(8):1417-1439. doi: 10.1016/j.clinph.2019.04.005. Epub 2019 Apr 27. Review.


Approaching Gossip and Rumor in Medical Education.

Chaikof M, Tannenbaum E, Mathur S, Bodley J, Farrugia M.

J Grad Med Educ. 2019 Apr;11(2):239-240. doi: 10.4300/JGME-D-19-00119.1. No abstract available.


The search for the definition, etiology, and effective diagnosis of upper urinary tract obstruction: the Whitaker test then and now.

Farrugia MK, Whitaker RH.

J Pediatr Urol. 2019 Feb;15(1):18-26. doi: 10.1016/j.jpurol.2018.11.011. Epub 2018 Nov 22. Review.


Incidental mastoid effusion diagnosed on imaging: Are we doing right by our patients?

Sayal NR, Boyd S, Zach White G, Farrugia M.

Laryngoscope. 2019 Apr;129(4):852-857. doi: 10.1002/lary.27452. Epub 2018 Dec 20.


Prognostic factors in breast cancer patients evaluated by positron-emission tomography/computed tomography before neoadjuvant chemotherapy.

Farrugia MK, Wen S, Jacobson GM, Salkeni MA.

World J Nucl Med. 2018 Oct-Dec;17(4):275-280. doi: 10.4103/wjnm.WJNM_84_17.


Cervico-vaginal inflammatory cytokine alterations after intrauterine contraceptive device insertion: A pilot study.

Sharma P, Shahabi K, Spitzer R, Farrugia M, Kaul R, Yudin M.

PLoS One. 2018 Dec 4;13(12):e0207266. doi: 10.1371/journal.pone.0207266. eCollection 2018.


Nε-lysine acetylation in the endoplasmic reticulum - a novel cellular mechanism that regulates proteostasis and autophagy.

Farrugia MA, Puglielli L.

J Cell Sci. 2018 Nov 16;131(22). pii: jcs221747. doi: 10.1242/jcs.221747. Review.


Outcome Measures for Central Nervous System Evaluation in Myotonic Dystrophy Type 1 May Be Confounded by Deficits in Motor Function or Insight.

Hamilton MJ, McLean J, Cumming S, Ballantyne B, McGhie J, Jampana R, Longman C, Evans JJ, Monckton DG, Farrugia ME.

Front Neurol. 2018 Oct 2;9:780. doi: 10.3389/fneur.2018.00780. eCollection 2018.


The randomised uterine septum transsection trial (TRUST): design and protocol.

Rikken JFW, Kowalik CR, Emanuel MH, Bongers MY, Spinder T, de Kruif JH, Bloemenkamp KWM, Jansen FW, Veersema S, Mulders AGMGJ, Thurkow AL, Hald K, Mohazzab A, Khalaf Y, Clark TJ, Farrugia M, van Vliet HA, Stephenson MS, van der Veen F, van Wely M, Mol BWJ, Goddijn M.

BMC Womens Health. 2018 Oct 5;18(1):163. doi: 10.1186/s12905-018-0637-6.


ECEL1 gene related contractural syndrome: Long-term follow-up and update on clinical and pathological aspects.

Ullmann U, D'Argenzio L, Mathur S, Whyte T, Quinlivan R, Longman C, Farrugia ME, Manzur A, Willis T, Jungbluth H, Pitt M, Cirak S; UK10K consortium, Feng L, Stewart W, Mein R, Phadke R, Sewry C, Sarkozy A, Muntoni F.

Neuromuscul Disord. 2018 Sep;28(9):741-749. doi: 10.1016/j.nmd.2018.05.012. Epub 2018 Jun 30.


De novo repeat interruptions are associated with reduced somatic instability and mild or absent clinical features in myotonic dystrophy type 1.

Cumming SA, Hamilton MJ, Robb Y, Gregory H, McWilliam C, Cooper A, Adam B, McGhie J, Hamilton G, Herzyk P, Tschannen MR, Worthey E, Petty R, Ballantyne B; Scottish Myotonic Dystrophy Consortium, Warner J, Farrugia ME, Longman C, Monckton DG.

Eur J Hum Genet. 2018 Nov;26(11):1635-1647. doi: 10.1038/s41431-018-0156-9. Epub 2018 Jul 2.


Venous thromboembolism after induced abortion: a population-based, propensity-score-matched cohort study in Canada.

Liu N, Vigod SN, Farrugia MM, Urquia ML, Ray JG.

Lancet Haematol. 2018 Jul;5(7):e279-e288. doi: 10.1016/S2352-3026(18)30069-3. Epub 2018 Jun 18.


A Physical and Psychological Approach to Managing Fatigue in Myasthenia Gravis: A Pilot Study.

Farrugia ME, Di Marco M, Kersel D, Carmichael C.

J Neuromuscul Dis. 2018;5(3):373-385. doi: 10.3233/JND-170299.


Intergenerational teen pregnancy: a population-based cohort study.

Liu N, Vigod SN, Farrugia MM, Urquia ML, Ray JG.

BJOG. 2018 Dec;125(13):1766-1774. doi: 10.1111/1471-0528.15297. Epub 2018 Jun 25.


The authors respond to "Failure to monitor or prevent unintended pregnancy is the key intergenerational problem, not the pregnancy outcome".

Liu N, Farrugia MM, Vigod SN, Urquia ML, Ray JG.

CMAJ. 2018 May 14;190(19):E601. doi: 10.1503/cmaj.69172. No abstract available.


A Structural Model of the Urease Activation Complex Derived from Ion Mobility-Mass Spectrometry and Integrative Modeling.

Eschweiler JD, Farrugia MA, Dixit SM, Hausinger RP, Ruotolo BT.

Structure. 2018 Apr 3;26(4):599-606.e3. doi: 10.1016/j.str.2018.03.001. Epub 2018 Mar 22.


Comparative Analysis of the Views of Oncologic Subspecialists and Palliative/Supportive Care Physicians Regarding Advanced Care Planning and End-of-Life Care.

Pifer PM, Farrugia MK, Mattes MD.

Am J Hosp Palliat Care. 2018 Oct;35(10):1287-1291. doi: 10.1177/1049909118763592. Epub 2018 Mar 7.


Mobility shift of beta-dystroglycan as a marker of GMPPB gene-related muscular dystrophy.

Sarkozy A, Torelli S, Mein R, Henderson M, Phadke R, Feng L, Sewry C, Ala P, Yau M, Bertoli M, Willis T, Hammans S, Manzur A, Sframeli M, Norwood F, Rakowicz W, Radunovic A, Vaidya SS, Parton M, Walker M, Marino S, Offiah C, Farrugia ME, Mamutse G, Marini-Bettolo C, Wraige E, Beeson D, Lochmüller H, Straub V, Bushby K, Barresi R, Muntoni F.

J Neurol Neurosurg Psychiatry. 2018 Jul;89(7):762-768. doi: 10.1136/jnnp-2017-316956. Epub 2018 Feb 3.


Intergenerational abortion tendency between mothers and teenage daughters: a population-based cohort study.

Liu N, Farrugia MM, Vigod SN, Urquia ML, Ray JG.

CMAJ. 2018 Jan 29;190(4):E95-E102. doi: 10.1503/cmaj.170595.


The Association of British Neurologists' myasthenia gravis guidelines.

Sussman J, Farrugia ME, Maddison P, Hill M, Leite MI, Hilton-Jones D.

Ann N Y Acad Sci. 2018 Jan;1412(1):166-169. doi: 10.1111/nyas.13503. Epub 2017 Nov 9.


A retrospective study of acetylcholine receptor antibody positive ocular myasthenia in the West of Scotland.

Farrugia ME, Cleary M, Carmichael C.

J Neurol Sci. 2017 Nov 15;382:84-86. doi: 10.1016/j.jns.2017.09.036. Epub 2017 Sep 27.


Ptosis Surgery in Patients with Myasthenia Gravis: A Useful Adjunct to Medical Therapy.

Brogan K, Farrugia ME, Crofts K.

Semin Ophthalmol. 2018;33(3):429-434. doi: 10.1080/08820538.2017.1284871. Epub 2017 Feb 22.


To which countries do European psychiatric trainees want to move to and why?

Pinto da Costa M, Giurgiuca A, Holmes K, Biskup E, Mogren T, Tomori S, Kilic O, Banjac V, Molina-Ruiz R, Palumbo C, Frydecka D, Kaaja J, El-Higaya E, Kanellopoulos A, Amit BH, Madissoon D, Andreou E, Uleviciute-Belena I, Rakos I, Dragasek J, Feffer K, Farrugia M, Mitkovic-Voncina M, Gargot T, Baessler F, Pantovic-Stefanovic M, De Picker L.

Eur Psychiatry. 2017 Sep;45:174-181. doi: 10.1016/j.eurpsy.2017.06.010. Epub 2017 Jul 10.


Heart Rate Variability in Obstetricians Working 14-Hour Call Compared to 24-Hour Call in Labour and Delivery.

Thurman RH, Yoon E, Murphy KE, Windrim R, Farrugia MM.

J Obstet Gynaecol Can. 2017 Dec;39(12):1156-1162. doi: 10.1016/j.jogc.2017.05.009. Epub 2017 Aug 4.


Editorial Comment.

Farrugia MK.

J Urol. 2017 Nov;198(5):1166. doi: 10.1016/j.juro.2017.05.087. Epub 2017 Jul 22. No abstract available.


The Role of Toll-Like Receptors in Autoimmune Diseases through Failure of the Self-Recognition Mechanism.

Farrugia M, Baron B.

Int J Inflam. 2017;2017:8391230. doi: 10.1155/2017/8391230. Epub 2017 May 3. Review.


Response to Editorial comments.

Farrugia MK, Ruano R.

J Pediatr Urol. 2017 Oct;13(5):543-544. doi: 10.1016/j.jpurol.2017.03.028. Epub 2017 Apr 21. No abstract available.


Report on The Society for Fetal Urology panel discussion on the selection criteria and intervention for fetal bladder outlet obstruction.

Farrugia MK, Braun MC, Peters CA, Ruano R, Herndon CD.

J Pediatr Urol. 2017 Aug;13(4):345-351. doi: 10.1016/j.jpurol.2017.02.021. Epub 2017 Mar 24.


Clinical Features, Molecular Heterogeneity, and Prognostic Implications in YARS2-Related Mitochondrial Myopathy.

Sommerville EW, Ng YS, Alston CL, Dallabona C, Gilberti M, He L, Knowles C, Chin SL, Schaefer AM, Falkous G, Murdoch D, Longman C, de Visser M, Bindoff LA, Rawles JM, Dean JCS, Petty RK, Farrugia ME, Haack TB, Prokisch H, McFarland R, Turnbull DM, Donnini C, Taylor RW, Gorman GS.

JAMA Neurol. 2017 Jun 1;74(6):686-694. doi: 10.1001/jamaneurol.2016.4357.


Correction: Elevated plasma levels of cardiac troponin-I predict left ventricular systolic dysfunction in patients with myotonic dystrophy type 1: A multicentre cohort follow-up study.

Hamilton MJ, Robb Y, Cumming S, Gregory H, Duncan A, Rahman M, McKeown A, McWilliam C, Dean J, Wilcox A, Farrugia ME, Cooper A, McGhie J, Adam B, Petty R; Scottish Myotonic Dystrophy Consortium, Longman C, Findlay I, Japp A, Monckton DG, Denvir MA.

PLoS One. 2017 Apr 6;12(4):e0175615. doi: 10.1371/journal.pone.0175615. eCollection 2017.


Elevated plasma levels of cardiac troponin-I predict left ventricular systolic dysfunction in patients with myotonic dystrophy type 1: A multicentre cohort follow-up study.

Hamilton MJ, Robb Y, Cumming S, Gregory H, Duncan A, Rahman M, McKeown A, McWilliam C, Dean J, Wilcox A, Farrugia ME, Cooper A, McGhie J, Adam B, Petty R; Scottish Myotonic Dystrophy Consortium, Longman C, Findlay I, Japp A, Monckton DG, Denvir MA.

PLoS One. 2017 Mar 21;12(3):e0174166. doi: 10.1371/journal.pone.0174166. eCollection 2017. Erratum in: PLoS One. 2017 Apr 6;12 (4):e0175615.


Application of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement to publications on endoscopic treatment for vesicoureteral reflux.

Farrugia MK, Kirsch AJ.

J Pediatr Urol. 2017 Jun;13(3):320-325. doi: 10.1016/j.jpurol.2017.02.005. Epub 2017 Feb 17.


Candida meningitis in an immunocompetent patient detected through (1→3)-beta-d-glucan.

Farrugia MK, Fogha EP, Miah AR, Yednock J, Palmer HC, Guilfoose J.

Int J Infect Dis. 2016 Oct;51:25-26. doi: 10.1016/j.ijid.2016.08.020. Epub 2016 Aug 30.


The role of TNF-α in rheumatoid arthritis: a focus on regulatory T cells.

Farrugia M, Baron B.

J Clin Transl Res. 2016 Sep 15;2(3):84-90. eCollection 2016 Nov 10. Review.


Fetal bladder outlet obstruction: Embryopathology, in utero intervention and outcome.

Farrugia MK.

J Pediatr Urol. 2016 Oct;12(5):296-303. doi: 10.1016/j.jpurol.2016.05.047. Epub 2016 Aug 6. Review.


International clinimetric evaluation of the MG-QOL15, resulting in slight revision and subsequent validation of the MG-QOL15r.

Burns TM, Sadjadi R, Utsugisawa K, Gwathmey KG, Joshi A, Jones S, Bril V, Barnett C, Guptill JT, Sanders DB, Hobson-Webb L, Juel VC, Massey J, Gable KL, Silvestri NJ, Wolfe G, Cutter G, Nagane Y, Murai H, Masuda M, Farrugia ME, Carmichael C, Birnbaum S, Hogrel JY, Nafissi S, Fatehi F, Ou C, Liu W, Conaway M.

Muscle Nerve. 2016 Dec;54(6):1015-1022. doi: 10.1002/mus.25198. Epub 2016 Nov 7.


Polydactyly: A Review.

Farrugia MC, Calleja-Agius J.

Neonatal Netw. 2016;35(3):135-42. doi: 10.1891/0730-0832.35.3.135. Review.


Clinical features of the myasthenic syndrome arising from mutations in GMPPB.

Rodríguez Cruz PM, Belaya K, Basiri K, Sedghi M, Farrugia ME, Holton JL, Liu WW, Maxwell S, Petty R, Walls TJ, Kennett R, Pitt M, Sarkozy A, Parton M, Lochmüller H, Muntoni F, Palace J, Beeson D.

J Neurol Neurosurg Psychiatry. 2016 Aug;87(8):802-9. doi: 10.1136/jnnp-2016-313163. Epub 2016 May 4.


Kruppel-like Pluripotency Factors as Modulators of Cancer Cell Therapeutic Responses.

Farrugia MK, Vanderbilt DB, Salkeni MA, Ruppert JM.

Cancer Res. 2016 Apr 1;76(7):1677-82. doi: 10.1158/0008-5472.CAN-15-1806. Epub 2016 Mar 10. Review.

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