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Items: 1 to 50 of 59

1.

Bacillus anthracis Edema Toxin Inhibits Efferocytosis in Human Macrophages and Alters Efferocytic Receptor Signaling.

Pan Z, Dumas EK, Lawrence C, Pate L, Longobardi S, Wang X, James JA, Kovats S, Farris AD.

Int J Mol Sci. 2019 Mar 7;20(5). pii: E1167. doi: 10.3390/ijms20051167.

2.

Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N-Glycosylation in Antibody-Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjögren's Syndrome.

Koelsch KA, Cavett J, Smith K, Moore JS, Lehoux SD, Jia N, Mather T, Quadri SMS, Rasmussen A, Kaufman CE, Lewis DM, Radfar L, Scordino TA, Lessard CJ, Kurien BT, Cummings RD, James JA, Sivils KL, Farris AD, Scofield RH.

Arthritis Rheumatol. 2018 Jul;70(7):1102-1113. doi: 10.1002/art.40458. Epub 2018 May 11.

3.

Minor salivary gland fibrosis in Sjögren's syndrome is elevated, associated with focus score and not solely a consequence of aging.

Leehan KM, Pezant NP, Rasmussen A, Grundahl K, Moore JS, Radfar L, Lewis DM, Stone DU, Lessard CJ, Rhodus NL, Segal BM, Scofield RH, Sivils KL, Montgomery C, Farris AD.

Clin Exp Rheumatol. 2018 May-Jun;36 Suppl 112(3):80-88. Epub 2017 Oct 23.

4.

Fatty infiltration of the minor salivary glands is a selective feature of aging but not Sjögren's syndrome.

Leehan KM, Pezant NP, Rasmussen A, Grundahl K, Moore JS, Radfar L, Lewis DM, Stone DU, Lessard CJ, Rhodus NL, Segal BM, Kaufman CE, Scofield RH, Sivils KL, Montgomery C, Farris AD.

Autoimmunity. 2017 Dec;50(8):451-457. doi: 10.1080/08916934.2017.1385776. Epub 2017 Oct 8.

5.

Anthrax Vaccine Precipitated Induces Edema Toxin-Neutralizing, Edema Factor-Specific Antibodies in Human Recipients.

Dumas EK, Gross T, Larabee J, Pate L, Cuthbertson H, Charlton S, Hallis B, Engler RJM, Collins LC Jr, Spooner CE, Chen H, Ballard J, James JA, Farris AD.

Clin Vaccine Immunol. 2017 Nov 6;24(11). pii: e00165-17. doi: 10.1128/CVI.00165-17. Print 2017 Nov.

6.

Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.

Li H, Reksten TR, Ice JA, Kelly JA, Adrianto I, Rasmussen A, Wang S, He B, Grundahl KM, Glenn SB, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta ML, Brun JG, Gøransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnström M, Cunninghame Graham DS, Patel K, Adler AJ, Farris AD, Brennan MT, Chodosh J, Gopalakrishnan R, Weisman MH, Venuturupalli S, Wallace DJ, Hefner KS, Houston GD, Huang AJW, Hughes PJ, Lewis DM, Radfar L, Vista ES, Edgar CE, Rohrer MD, Stone DU, Vyse TJ, Harley JB, Gaffney PM, James JA, Turner S, Alevizos I, Anaya JM, Rhodus NL, Segal BM, Montgomery CG, Scofield RH, Kovats S, Mariette X, Rönnblom L, Witte T, Rischmueller M, Wahren-Herlenius M, Omdal R, Jonsson R, Ng WF; for UK Primary Sjögren's Syndrome Registry, Nordmark G, Lessard CJ, Sivils KL.

PLoS Genet. 2017 Jun 22;13(6):e1006820. doi: 10.1371/journal.pgen.1006820. eCollection 2017 Jun.

7.

Lethal factor antibodies contribute to lethal toxin neutralization in recipients of anthrax vaccine precipitated.

Dumas EK, Garman L, Cuthbertson H, Charlton S, Hallis B, Engler RJM, Choudhari S, Picking WD, James JA, Farris AD.

Vaccine. 2017 Jun 8;35(26):3416-3422. doi: 10.1016/j.vaccine.2017.05.006. Epub 2017 May 11.

8.

Single-cell analysis of glandular T cell receptors in Sjögren's syndrome.

Joachims ML, Leehan KM, Lawrence C, Pelikan RC, Moore JS, Pan Z, Rasmussen A, Radfar L, Lewis DM, Grundahl KM, Kelly JA, Wiley GB, Shugay M, Chudakov DM, Lessard CJ, Stone DU, Scofield RH, Montgomery CG, Sivils KL, Thompson LF, Farris AD.

JCI Insight. 2016 Jun 2;1(8). pii: e85609.

9.

Unique Inflammatory Mediators and Specific IgE Levels Distinguish Local from Systemic Reactions after Anthrax Vaccine Adsorbed Vaccination.

Garman L, Smith K, Muns EE, Velte CA, Spooner CE, Munroe ME, Farris AD, Nelson MR, Engler RJ, James JA.

Clin Vaccine Immunol. 2016 Aug 5;23(8):664-71. doi: 10.1128/CVI.00092-16. Print 2016 Aug.

11.

Ribosomal and immune transcripts associate with relapse in acquired ADAMTS13-deficient thrombotic thrombocytopenic purpura.

Edgar CE, Terrell DR, Vesely SK, Wren JD, Dozmorov IM, Niewold TB, Brown M, Zhou F, Frank MB, Merrill JT, Kremer Hovinga JA, Lämmle B, James JA, George JN, Farris AD.

PLoS One. 2015 Feb 11;10(2):e0117614. doi: 10.1371/journal.pone.0117614. eCollection 2015.

12.

Defective selection of thymic regulatory T cells accompanies autoimmunity and pulmonary infiltrates in Tcra-deficient mice double transgenic for human La/Sjögren's syndrome-B and human La-specific TCR.

Yaciuk JC, Pan Y, Schwarz K, Pan ZJ, Maier-Moore JS, Kosanke SD, Lawrence C, Farris AD.

J Immunol. 2015 Feb 15;194(4):1514-22. doi: 10.4049/jimmunol.1400319. Epub 2015 Jan 12.

13.

Antibody-secreting cell specificity in labial salivary glands reflects the clinical presentation and serology in patients with Sjögren's syndrome.

Maier-Moore JS, Koelsch KA, Smith K, Lessard CJ, Radfar L, Lewis D, Kurien BT, Wolska N, Deshmukh U, Rasmussen A, Sivils KL, James JA, Farris AD, Scofield RH.

Arthritis Rheumatol. 2014 Dec;66(12):3445-56. doi: 10.1002/art.38872.

14.

Protective antigen-specific memory B cells persist years after anthrax vaccination and correlate with humoral immunity.

Garman L, Smith K, Farris AD, Nelson MR, Engler RJ, James JA.

Toxins (Basel). 2014 Aug 13;6(8):2424-31. doi: 10.3390/toxins6082424.

15.

Interleukin-6 deficiency corrects nephritis, lymphocyte abnormalities, and secondary Sjögren's syndrome features in lupus-prone Sle1.Yaa mice.

Maier-Moore JS, Horton CG, Mathews SA, Confer AW, Lawrence C, Pan Z, Coggeshall KM, Farris AD.

Arthritis Rheumatol. 2014 Sep;66(9):2521-31. doi: 10.1002/art.38716.

16.

Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome.

Altorok N, Coit P, Hughes T, Koelsch KA, Stone DU, Rasmussen A, Radfar L, Scofield RH, Sivils KL, Farris AD, Sawalha AH.

Arthritis Rheumatol. 2014 Mar;66(3):731-9. doi: 10.1002/art.38264.

17.

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.

Lessard CJ, Li H, Adrianto I, Ice JA, Rasmussen A, Grundahl KM, Kelly JA, Dozmorov MG, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta ML, Brun JG, Gøransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnström M, Jazebi H, Cunninghame Graham DS, Grandits ME, Nazmul-Hossain AN, Patel K, Adler AJ, Maier-Moore JS, Farris AD, Brennan MT, Lessard JA, Chodosh J, Gopalakrishnan R, Hefner KS, Houston GD, Huang AJ, Hughes PJ, Lewis DM, Radfar L, Rohrer MD, Stone DU, Wren JD, Vyse TJ, Gaffney PM, James JA, Omdal R, Wahren-Herlenius M, Illei GG, Witte T, Jonsson R, Rischmueller M, Rönnblom L, Nordmark G, Ng WF; UK Primary Sjögren's Syndrome Registry, Mariette X, Anaya JM, Rhodus NL, Segal BM, Scofield RH, Montgomery CG, Harley JB, Sivils KL.

Nat Genet. 2013 Nov;45(11):1284-92. doi: 10.1038/ng.2792. Epub 2013 Oct 6.

18.

Comparison of the American-European Consensus Group Sjogren's syndrome classification criteria to newly proposed American College of Rheumatology criteria in a large, carefully characterised sicca cohort.

Rasmussen A, Ice JA, Li H, Grundahl K, Kelly JA, Radfar L, Stone DU, Hefner KS, Anaya JM, Rohrer M, Gopalakrishnan R, Houston GD, Lewis DM, Chodosh J, Harley JB, Hughes P, Maier-Moore JS, Montgomery CG, Rhodus NL, Farris AD, Segal BM, Jonsson R, Lessard CJ, Scofield RH, Sivils KL.

Ann Rheum Dis. 2014 Jan;73(1):31-8. doi: 10.1136/annrheumdis-2013-203845. Epub 2013 Aug 22.

19.

Stochastic humoral immunity to Bacillus anthracis protective antigen: identification of anti-peptide IgG correlating with seroconversion to Lethal Toxin neutralization.

Dumas EK, Nguyen ML, Cox PM, Rodgers H, Peterson JL, James JA, Farris AD.

Vaccine. 2013 Apr 3;31(14):1856-63. doi: 10.1016/j.vaccine.2013.01.040. Epub 2013 Feb 13.

20.

MHC class II and non-MHC class II genes differentially influence humoral immunity to Bacillus anthracis lethal factor and protective antigen.

Garman L, Dumas EK, Kurella S, Hunt JJ, Crowe SR, Nguyen ML, Cox PM, James JA, Farris AD.

Toxins (Basel). 2012 Dec;4(12):1451-67.

21.

Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity.

Andrews SF, Zhang Q, Lim S, Li L, Lee JH, Zheng NY, Huang M, Taylor WM, Farris AD, Ni D, Meng W, Luning Prak ET, Wilson PC.

J Exp Med. 2013 Jan 14;210(1):125-42. doi: 10.1084/jem.20120525. Epub 2012 Dec 24.

22.

Human monoclonal antibodies generated following vaccination with AVA provide neutralization by blocking furin cleavage but not by preventing oligomerization.

Smith K, Crowe SR, Garman L, Guthridge CJ, Muther JJ, McKee E, Zheng NY, Farris AD, Guthridge JM, Wilson PC, James JA.

Vaccine. 2012 Jun 13;30(28):4276-83. doi: 10.1016/j.vaccine.2012.03.002. Epub 2012 Mar 14.

23.

Toll-like receptors in systemic lupus erythematosus: potential targets for therapeutic intervention.

Horton CG, Farris AD.

Curr Allergy Asthma Rep. 2012 Feb;12(1):1-7. doi: 10.1007/s11882-011-0234-3. Review.

24.

Anthrax lethal toxin-induced gene expression changes in mouse lung.

Dumas EK, Cox PM, Fullenwider CO, Nguyen M, Centola M, Frank MB, Dozmorov I, James JA, Farris AD.

Toxins (Basel). 2011 Sep;3(9):1111-30. doi: 10.3390/toxins3091111. Epub 2011 Sep 7.

25.

Anthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity.

Crowe SR, Garman L, Engler RJ, Farris AD, Ballard JD, Harley JB, James JA.

Vaccine. 2011 May 9;29(20):3670-8. doi: 10.1016/j.vaccine.2011.03.011. Epub 2011 Mar 21.

26.

Targeting Toll-like receptors for treatment of SLE.

Horton CG, Pan ZJ, Farris AD.

Mediators Inflamm. 2010;2010. pii: 498980. doi: 10.1155/2010/498980. Epub 2010 Sep 19. Review.

27.

Select human anthrax protective antigen epitope-specific antibodies provide protection from lethal toxin challenge.

Crowe SR, Ash LL, Engler RJ, Ballard JD, Harley JB, Farris AD, James JA.

J Infect Dis. 2010 Jul 15;202(2):251-60. doi: 10.1086/653495.

28.

CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1.

Charles E, Joshi S, Ash JD, Fox BA, Farris AD, Bzik DJ, Lang ML, Blader IJ.

Infect Immun. 2010 Aug;78(8):3484-92. doi: 10.1128/IAI.00117-10. Epub 2010 May 24.

29.

The major neutralizing antibody responses to recombinant anthrax lethal and edema factors are directed to non-cross-reactive epitopes.

Nguyen ML, Terzyan S, Ballard JD, James JA, Farris AD.

Infect Immun. 2009 Nov;77(11):4714-23. doi: 10.1128/IAI.00749-09. Epub 2009 Aug 31.

30.

Toll-like receptor 7 (TLR7) modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells.

Pan ZJ, Maier S, Schwarz K, Azbill J, Akira S, Uematsu S, Farris AD.

Ann Rheum Dis. 2010 Jun;69(6):1195-9. doi: 10.1136/ard.2009.108282. Epub 2009 Aug 11.

31.

Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals.

Maeda K, Malykhin A, Teague-Weber BN, Sun XH, Farris AD, Coggeshall KM.

Blood. 2009 May 7;113(19):4534-40. doi: 10.1182/blood-2008-12-192559. Epub 2009 Feb 17.

32.

Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.

Duty JA, Szodoray P, Zheng NY, Koelsch KA, Zhang Q, Swiatkowski M, Mathias M, Garman L, Helms C, Nakken B, Smith K, Farris AD, Wilson PC.

J Exp Med. 2009 Jan 16;206(1):139-51. doi: 10.1084/jem.20080611. Epub 2008 Dec 22.

33.

Sequential B-cell epitopes of Bacillus anthracis lethal factor bind lethal toxin-neutralizing antibodies.

Nguyen ML, Crowe SR, Kurella S, Teryzan S, Cao B, Ballard JD, James JA, Farris AD.

Infect Immun. 2009 Jan;77(1):162-9. doi: 10.1128/IAI.00788-08. Epub 2008 Nov 3.

34.

Early and dynamic polarization of T cell membrane rafts and constituents prior to TCR stop signals.

Van Komen JS, Mishra S, Byrum J, Chichili GR, Yaciuk JC, Farris AD, Rodgers W.

J Immunol. 2007 Nov 15;179(10):6845-55.

35.

T cell epitopes of the La/SSB autoantigen in humanized transgenic mice expressing the HLA class II haplotype DRB1*0301/DQB1*0201.

Dudek NL, Maier S, Chen ZJ, Mudd PA, Mannering SI, Jackson DC, Zeng W, Keech CL, Hamlin K, Pan ZJ, Davis-Schwarz K, Workman-Azbill J, Bachmann M, McCluskey J, Farris AD.

Arthritis Rheum. 2007 Oct;56(10):3387-98.

36.

Detection of a rare oligo(A) repeat tract mutation (8As-->7As) in the sequence encoding the La/SS-B autoantigen.

Semsei I, Maier S, Workman-Azbill J, Urbán L, Moser K, Zeher M, Bachmann M, Farris AD.

Anal Biochem. 2007 Nov 1;370(1):47-53. Epub 2007 Jul 5.

37.

Proteinuria of nonautoimmune origin in wild-type FVB/NJ mice.

Maier SM, Gross JK, Hamlin KL, Maier JL, Workman JL, Kim-Howard XR, Schoeb TR, Farris AD.

Comp Med. 2007 Jun;57(3):255-66.

PMID:
17605340
38.

Cutting edge: Transitional T3 B cells do not give rise to mature B cells, have undergone selection, and are reduced in murine lupus.

Teague BN, Pan Y, Mudd PA, Nakken B, Zhang Q, Szodoray P, Kim-Howard X, Wilson PC, Farris AD.

J Immunol. 2007 Jun 15;178(12):7511-5.

39.

Anti-nuclear antibody production and autoimmunity in transgenic mice that overexpress the transcription factor Bright.

Shankar M, Nixon JC, Maier S, Workman J, Farris AD, Webb CF.

J Immunol. 2007 Mar 1;178(5):2996-3006.

40.

Regulatory T cells and systemic lupus erythematosus.

Mudd PA, Teague BN, Farris AD.

Scand J Immunol. 2006 Sep;64(3):211-8. Review.

41.

Autoimmunity as a result of escape from RNA surveillance.

Bachmann MP, Bartsch H, Gross JK, Maier SM, Gross TF, Workman JL, James JA, Farris AD, Jung B, Franke C, Conrad K, Schmitz M, Büttner C, Buyon JP, Semsei I, Harley JB, Rieber EP.

J Immunol. 2006 Aug 1;177(3):1698-707.

42.

Neo-epitopes are required for immunogenicity of the La/SS-B nuclear antigen in the context of late apoptotic cells.

Pan ZJ, Davis K, Maier S, Bachmann MP, Kim-Howard XR, Keech C, Gordon TP, McCluskey J, Farris AD.

Clin Exp Immunol. 2006 Feb;143(2):237-48.

43.

Transcriptional modulation of TCR, Notch and Wnt signaling pathways in SEB-anergized CD4+ T cells.

Kurella S, Yaciuk JC, Dozmorov I, Frank MB, Centola M, Farris AD.

Genes Immun. 2005 Oct;6(7):596-608.

44.

T-helper cell tolerance to ubiquitous nuclear antigens.

Nakken B, Davis KE, Pan ZJ, Bachmann M, Farris AD.

Scand J Immunol. 2003 Nov;58(5):478-92. Review.

45.

Cognate T cell help is sufficient to trigger anti-nuclear autoantibodies in naive mice.

Keech CL, Farris AD, Beroukas D, Gordon TP, McCluskey J.

J Immunol. 2001 May 1;166(9):5826-34.

46.

Characterization and genomic sequence of the murine 60 kD Ro gene.

Kaufman KM, Farris AD, Gross JK, Kirby MY, Harley JB.

Genes Immun. 2000;1(4):265-70.

47.

Epitope mimics and determinant spreading: pathways to autoimmunity.

Farris AD, Keech CL, Gordon TP, McCluskey J.

Cell Mol Life Sci. 2000 Apr;57(4):569-78. Review.

PMID:
11130457
48.

Conserved features of Y RNAs: a comparison of experimentally derived secondary structures.

Teunissen SW, Kruithof MJ, Farris AD, Harley JB, Venrooij WJ, Pruijn GJ.

Nucleic Acids Res. 2000 Jan 15;28(2):610-9.

49.

Photosensitivity diseases: cutaneous lupus erythematosus.

Lee LA, Farris AD.

J Investig Dermatol Symp Proc. 1999 Sep;4(1):73-8. Review.

50.

Induction of autoimmunity by multivalent immunodominant and subdominant T cell determinants of La (SS-B).

Farris AD, Brown L, Reynolds P, Harley JB, James JA, Scofield RH, McCluskey J, Gordon TP.

J Immunol. 1999 Mar 1;162(5):3079-87.

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