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Items: 44

1.

Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC).

Ward RA, Anderton MJ, Bethel P, Breed J, Cook C, Davies EJ, Dobson A, Dong Z, Fairley G, Farrington P, Feron L, Flemington V, Gibbons FD, Graham MA, Greenwood R, Hanson L, Hopcroft P, Howells R, Hudson J, James M, Jones CD, Jones CR, Li Y, Lamont S, Lewis R, Lindsay N, McCabe J, McGuire T, Rawlins P, Roberts K, Sandin L, Simpson I, Swallow S, Tang J, Tomkinson G, Tonge M, Wang Z, Zhai B.

J Med Chem. 2019 Nov 25. doi: 10.1021/acs.jmedchem.9b01295. [Epub ahead of print]

PMID:
31710489
2.

AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity.

Fok JHL, Ramos-Montoya A, Vazquez-Chantada M, Wijnhoven PWG, Follia V, James N, Farrington PM, Karmokar A, Willis SE, Cairns J, Nikkilä J, Beattie D, Lamont GM, Finlay MRV, Wilson J, Smith A, O'Connor LO, Ling S, Fawell SE, O'Connor MJ, Hollingsworth SJ, Dean E, Goldberg FW, Davies BR, Cadogan EB.

Nat Commun. 2019 Nov 7;10(1):5065. doi: 10.1038/s41467-019-12836-9.

3.

Quadrivalent human papillomavirus vaccination in girls and the risk of autoimmune disorders: the Ontario Grade 8 HPV Vaccine Cohort Study.

Liu EY, Smith LM, Ellis AK, Whitaker H, Law B, Kwong JC, Farrington P, Lévesque LE.

CMAJ. 2018 May 28;190(21):E648-E655. doi: 10.1503/cmaj.170871.

4.

Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice.

Karlin J, Allen J, Ahmad SF, Hughes G, Sheridan V, Odedra R, Farrington P, Cadogan EB, Riches LC, Garcia-Trinidad A, Thomason AG, Patel B, Vincent J, Lau A, Pike KG, Hunt TA, Sule A, Valerie NCK, Biddlestone-Thorpe L, Kahn J, Beckta JM, Mukhopadhyay N, Barlaam B, Degorce SL, Kettle J, Colclough N, Wilson J, Smith A, Barrett IP, Zheng L, Zhang T, Wang Y, Chen K, Pass M, Durant ST, Valerie K.

Mol Cancer Ther. 2018 Aug;17(8):1637-1647. doi: 10.1158/1535-7163.MCT-17-0975. Epub 2018 May 16.

5.

Risk of Injection-Site Abscess among Infants Receiving a Preservative-Free, Two-Dose Vial Formulation of Pneumococcal Conjugate Vaccine in Kenya.

Burton DC, Bigogo GM, Audi AO, Williamson J, Munge K, Wafula J, Ouma D, Khagayi S, Mugoya I, Mburu J, Muema S, Bauni E, Bwanaali T, Feikin DR, Ochieng PM, Mogeni OD, Otieno GA, Olack B, Kamau T, Van Dyke MK, Chen R, Farrington P, Montgomery JM, Breiman RF, Scott JA, Laserson KF.

PLoS One. 2015 Oct 28;10(10):e0141896. doi: 10.1371/journal.pone.0141896. eCollection 2015.

6.

Estimating seroprevalence of vaccine-preventable infections: is it worth standardizing the serological outcomes to adjust for different assays and laboratories?

Kafatos G, Andrews N, McConway KJ, Anastassopoulou C, Barbara C, De Ory F, Johansen K, Mossong J, Prosenc K, Vranckx R, Nardone A, Pebody R, Farrington P.

Epidemiol Infect. 2015 Aug;143(11):2269-78. doi: 10.1017/S095026881400301X. Epub 2014 Nov 25.

PMID:
25420586
7.

Validation of the French national health insurance information system as a tool in vaccine safety assessment: application to febrile convulsions after pediatric measles/mumps/rubella immunization.

Hanf M, Quantin C, Farrington P, Benzenine E, Hocine NM, Velten M, Tubert-Bitter P, Escolano S.

Vaccine. 2013 Dec 2;31(49):5856-62. doi: 10.1016/j.vaccine.2013.09.052. Epub 2013 Oct 14.

PMID:
24135575
8.

Censoring on outcome is not valid in self-controlled case series studies.

Farrington P.

J Clin Epidemiol. 2013 Dec;66(12):1428-9. doi: 10.1016/j.jclinepi.2013.06.010. Epub 2013 Sep 3. No abstract available.

PMID:
24012151
9.

Genome-wide association study link novel loci to endometriosis.

Albertsen HM, Chettier R, Farrington P, Ward K.

PLoS One. 2013;8(3):e58257. doi: 10.1371/journal.pone.0058257. Epub 2013 Mar 5.

10.

Regression models for censored serological data.

Kafatos G, Andrews N, McConway KJ, Farrington P.

J Med Microbiol. 2013 Jan;62(Pt 1):93-100. doi: 10.1099/jmm.0.050062-0. Epub 2012 Sep 20.

PMID:
23002068
11.

An improved algorithm for outbreak detection in multiple surveillance systems.

Noufaily A, Enki DG, Farrington P, Garthwaite P, Andrews N, Charlett A.

Stat Med. 2013 Mar 30;32(7):1206-22. doi: 10.1002/sim.5595. Epub 2012 Sep 2.

PMID:
22941770
12.

Mortality and the self-controlled case series method: letter to the editor.

Farrington P, Whitaker H.

Pharmacoepidemiol Drug Saf. 2012 Aug;21(8):906; author reply 907. doi: 10.1002/pds.3273. No abstract available.

PMID:
22836721
13.

Antipsychotic use and myocardial infarction in older patients with treated dementia.

Pariente A, Fourrier-Réglat A, Ducruet T, Farrington P, Béland SG, Dartigues JF, Moore N, Moride Y.

Arch Intern Med. 2012 Apr 23;172(8):648-53; discussion 654-5. doi: 10.1001/archinternmed.2012.28. Epub 2012 Mar 26.

PMID:
22450214
14.

Pony measurement: size really does matter.

McEwen J, Farrington P.

Vet J. 2007 Jul;174(1):1-3. Epub 2007 May 31. No abstract available.

PMID:
17543557
15.

Use of nicotine replacement therapy and the risk of acute myocardial infarction, stroke, and death.

Hubbard R, Lewis S, Smith C, Godfrey C, Smeeth L, Farrington P, Britton J.

Tob Control. 2005 Dec;14(6):416-21.

16.

Bupropion and the risk of sudden death: a self-controlled case-series analysis using The Health Improvement Network.

Hubbard R, Lewis S, West J, Smith C, Godfrey C, Smeeth L, Farrington P, Britton J.

Thorax. 2005 Oct;60(10):848-50. Epub 2005 Jul 29.

17.
18.

Risk of myocardial infarction and stroke after acute infection or vaccination.

Smeeth L, Thomas SL, Hall AJ, Hubbard R, Farrington P, Vallance P.

N Engl J Med. 2004 Dec 16;351(25):2611-8.

19.
20.

Clinical trials.

Farrington P, Miller E.

Methods Mol Med. 2003;87:335-52. No abstract available.

PMID:
12958466
21.

Exposure to tricyclic and selective serotonin reuptake inhibitor antidepressants and the risk of hip fracture.

Hubbard R, Farrington P, Smith C, Smeeth L, Tattersfield A.

Am J Epidemiol. 2003 Jul 1;158(1):77-84.

PMID:
12835289
22.

Does oral polio vaccine cause intussusception in infants? Evidence from a sequence of three self-controlled cases series studies in the United Kingdom.

Andrews N, Miller E, Waight P, Farrington P, Crowcroft N, Stowe J, Taylor B.

Eur J Epidemiol. 2001;17(8):701-6.

PMID:
12086086
23.

Meningococcal vaccine trials.

Farrington P, Miller E.

Methods Mol Med. 2001;66:371-93. doi: 10.1385/1-59259-148-5:371.

PMID:
21336769
24.

The European Sero-Epidemiology Network: standardizing the enzyme immunoassay results for measles, mumps and rubella.

Andrews N, Pebody RG, Berbers G, Blondeau C, Crovari P, Davidkin I, Farrington P, Fievet-Groyne F, Gabutti G, Gerike E, Giordano C, Hesketh L, Marzec T, Morgan-Capner P, Osborne K, Pleisner AM, Raux M, Tischer A, Ruden U, Valle M, Miller E.

Epidemiol Infect. 2000 Aug;125(1):127-41.

25.

Safety assessment post-licensure.

Miller E, Waight P, Farrington P.

Dev Biol Stand. 1998;95:235-43.

PMID:
9855437
26.

Risk of hepatitis A infection in sewage workers.

Brugha R, Heptonstall J, Farrington P, Andren S, Perry K, Parry J.

Occup Environ Med. 1998 Aug;55(8):567-9.

27.

Myotonic dystrophy is a significant cause of idiopathic polyhydramnios.

Esplin MS, Hallam S, Farrington PF, Nelson L, Byrne J, Ward K.

Am J Obstet Gynecol. 1998 Oct;179(4):974-7.

PMID:
9790382
28.

The Melt Viscosity of Dendritic Poly(benzyl ether) Macromolecules.

Farrington PJ, Hawker CJ, Fréchet JMJ, Mackay ME.

Macromolecules. 1998 Jul 28;31(15):5043-50.

PMID:
9680444
29.

Risk factors for winter outbreak of acute diarrhoea in France. Winter outbreaks of diarrhoea occur in United Kingdom too.

Djuretic T, Ramsey ME, Farrington PC, Fleming DM, Brown D.

BMJ. 1998 Jul 11;317(7151):145; author reply 146. No abstract available.

30.

An evaluation of nine commercial EIA kits for the detection of measles specific IgG.

Hesketh L, Charlett A, Farrington P, Miller E, Forsey T, Morgan-Capner P.

J Virol Methods. 1997 Jun;66(1):51-9.

PMID:
9220390
31.

Changing patterns of case ascertainment and trends in meningococcal disease in England and Wales.

Ramsay M, Kaczmarski E, Rush M, Mallard R, Farrington P, White J.

Commun Dis Rep CDR Rev. 1997 Apr 4;7(4):R49-54.

PMID:
9127510
32.

Pediatric vulvo-vaginitis.

Farrington PF.

Clin Obstet Gynecol. 1997 Mar;40(1):135-40. Review. No abstract available.

PMID:
9103956
33.

Clinical trials.

Farrington P, Miller E.

Methods Mol Med. 1996;4:251-68. doi: 10.1385/0-89603-334-1:251.

PMID:
21359709
34.

Measles vaccination as a risk factor for inflammatory bowel disease.

Farrington P, Miller E.

Lancet. 1995 May 27;345(8961):1362. No abstract available.

PMID:
7752764
35.

A new method for active surveillance of adverse events from diphtheria/tetanus/pertussis and measles/mumps/rubella vaccines.

Farrington P, Pugh S, Colville A, Flower A, Nash J, Morgan-Capner P, Rush M, Miller E.

Lancet. 1995 Mar 4;345(8949):567-9.

PMID:
7619183
36.

A molecular variant of angiotensinogen associated with preeclampsia.

Ward K, Hata A, Jeunemaitre X, Helin C, Nelson L, Namikawa C, Farrington PF, Ogasawara M, Suzumori K, Tomoda S, et al.

Nat Genet. 1993 May;4(1):59-61.

PMID:
8513325
37.

Risk of aseptic meningitis after measles, mumps, and rubella vaccine in UK children.

Miller E, Goldacre M, Pugh S, Colville A, Farrington P, Flower A, Nash J, MacFarlane L, Tettmar R.

Lancet. 1993 Apr 17;341(8851):979-82.

PMID:
8096942
38.

Shift in age in chickenpox.

Miller E, Vardien J, Farrington P.

Lancet. 1993 Jan 30;341(8840):308-9. No abstract available.

PMID:
8093945
39.

Atypical myoglobinuria: an acute myopathy in grazing horses.

Whitwell KE, Harris P, Farrington PG.

Equine Vet J. 1988 Sep;20(5):357-63. Review.

PMID:
3053157
40.

Congenital disseminated herpes simplex virus type II infection in a premature infant.

Beck R, Park T, Farrington P, Steigman CK, Sennesh JD.

Am J Perinatol. 1987 Oct;4(4):334-8.

PMID:
3651193
41.

Immunization activities.

Farrington PH.

J Ark Med Soc. 1973 Dec;70(7):250-1. No abstract available.

PMID:
4272004
42.

Modifications of the Metzenbaum and Masson needle holders.

FARRINGTON PR.

Am J Surg. 1953 Dec;86(6):760. No abstract available.

PMID:
13104793
43.

The prevention of mumps in adults; preliminary report.

FARRINGTON PR.

Rocky Mt Med J. 1950 Sep;47(9):680-1. No abstract available.

PMID:
14781664
44.

Closure of a defect of the skull with tantalum.

FARRINGTON PR.

Rocky Mt Med J. 1945 Nov;42:842-4. No abstract available.

PMID:
21004113

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