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Items: 31

1.
2.

Serum Inflammatory and Immune Mediators Are Elevated in Early Stage Diabetic Nephropathy.

Perlman AS, Chevalier JM, Wilkinson P, Liu H, Parker T, Levine DM, Sloan BJ, Gong A, Sherman R, Farrell FX.

Ann Clin Lab Sci. 2015 Spring;45(3):256-63.

PMID:
26116588
3.

Macrophage-derived tumor necrosis factor-α mediates diabetic renal injury.

Awad AS, You H, Gao T, Cooper TK, Nedospasov SA, Vacher J, Wilkinson PF, Farrell FX, Brian Reeves W.

Kidney Int. 2015 Oct;88(4):722-33. doi: 10.1038/ki.2015.162. Epub 2015 Jun 10.

4.

Proinflammatory/profibrotic effects of interleukin-17A on human proximal tubule epithelium.

Dudas PL, Sague SL, Elloso MM, Farrell FX.

Nephron Exp Nephrol. 2011;117(4):e114-23. doi: 10.1159/000320177. Epub 2010 Oct 2.

PMID:
20924205
5.

Generation of bleomycin-induced lung fibrosis is independent of IL-16.

Glass WG, Argentieri RL, Bracht M, Farrell FX, Das AM, Del Vecchio AM, Hogaboam CM, Murray LA.

Cytokine. 2009 Apr;46(1):17-23. doi: 10.1016/j.cyto.2008.11.007. Epub 2009 Feb 15.

PMID:
19232499
6.

BMP-7 does not protect against bleomycin-induced lung or skin fibrosis.

Murray LA, Hackett TL, Warner SM, Shaheen F, Argentieri RL, Dudas P, Farrell FX, Knight DA.

PLoS One. 2008;3(12):e4039. doi: 10.1371/journal.pone.0004039. Epub 2008 Dec 29.

7.

BMP-7 fails to attenuate TGF-beta1-induced epithelial-to-mesenchymal transition in human proximal tubule epithelial cells.

Dudas PL, Argentieri RL, Farrell FX.

Nephrol Dial Transplant. 2009 May;24(5):1406-16. doi: 10.1093/ndt/gfn662. Epub 2008 Dec 4.

PMID:
19056781
8.

Hyper-responsiveness of IPF/UIP fibroblasts: interplay between TGFbeta1, IL-13 and CCL2.

Murray LA, Argentieri RL, Farrell FX, Bracht M, Sheng H, Whitaker B, Beck H, Tsui P, Cochlin K, Evanoff HL, Hogaboam CM, Das AM.

Int J Biochem Cell Biol. 2008;40(10):2174-82. doi: 10.1016/j.biocel.2008.02.016. Epub 2008 Feb 23.

PMID:
18395486
9.

Expression and characterization of a human BMP-7 variant with improved biochemical properties.

Swencki-Underwood B, Mills JK, Vennarini J, Boakye K, Luo J, Pomerantz S, Cunningham MR, Farrell FX, Naso MF, Amegadzie B.

Protein Expr Purif. 2008 Feb;57(2):312-9. Epub 2007 Oct 1.

PMID:
17977014
10.

Recombinant epoetins do not stimulate tumor growth in erythropoietin receptor-positive breast carcinoma models.

LaMontagne KR, Butler J, Marshall DJ, Tullai J, Gechtman Z, Hall C, Meshaw A, Farrell FX.

Mol Cancer Ther. 2006 Feb;5(2):347-55.

11.

An in vivo model to assess factors that may stimulate the generation of an immune reaction to erythropoietin.

Ryan MH, Heavner GA, Brigham-Burke M, McMahon F, Shanahan MF, Gunturi SR, Sharma B, Farrell FX.

Int Immunopharmacol. 2006 Apr;6(4):647-55. Epub 2005 Nov 14.

PMID:
16504928
12.

Erytropoietin concentrations in cerebrospinal fluid of nonhuman primates and fetal sheep following high-dose recombinant erythropoietin.

Juul SE, McPherson RJ, Farrell FX, Jolliffe L, Ness DJ, Gleason CA.

Biol Neonate. 2004;85(2):138-44. Epub 2003 Nov 24.

PMID:
14639039
13.

Erythropoietin induces changes in gene expression in PC-12 cells.

Renzi MJ, Farrell FX, Bittner A, Galindo JE, Morton M, Trinh H, Jolliffe LK.

Brain Res Mol Brain Res. 2002 Jul 15;104(1):86-95.

PMID:
12117554
14.

Synthesis and erythropoietin receptor binding affinities of N,N-disubstituted amino acids.

Connolly PJ, Wetter SK, Murray WV, Johnson DL, McMahon FJ, Farrell FX, Tullai J, Jolliffe LK.

Bioorg Med Chem Lett. 2000 Sep 4;10(17):1995-9.

PMID:
10987435
15.

New epoetin molecules and novel therapeutic approaches.

Barbone FP, Johnson DL, Farrell FX, Collins A, Middleton SA, McMahon FJ, Tullai J, Jolliffe LK.

Nephrol Dial Transplant. 1999;14 Suppl 2:80-4. Review.

PMID:
10334672
16.

Shared and unique determinants of the erythropoietin (EPO) receptor are important for binding EPO and EPO mimetic peptide.

Middleton SA, Barbone FP, Johnson DL, Thurmond RL, You Y, McMahon FJ, Jin R, Livnah O, Tullai J, Farrell FX, Goldsmith MA, Wilson IA, Jolliffe LK.

J Biol Chem. 1999 May 14;274(20):14163-9.

17.

An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation.

Livnah O, Johnson DL, Stura EA, Farrell FX, Barbone FP, You Y, Liu KD, Goldsmith MA, He W, Krause CD, Pestka S, Jolliffe LK, Wilson IA.

Nat Struct Biol. 1998 Nov;5(11):993-1004.

PMID:
9808045
18.

Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1.

Johnson DL, Farrell FX, Barbone FP, McMahon FJ, Tullai J, Hoey K, Livnah O, Wrighton NC, Middleton SA, Loughney DA, Stura EA, Dower WJ, Mulcahy LS, Wilson IA, Jolliffe LK.

Biochemistry. 1998 Mar 17;37(11):3699-710.

PMID:
9521688
19.

Amino-terminal dimerization of an erythropoietin mimetic peptide results in increased erythropoietic activity.

Johnson DL, Farrell FX, Barbone FP, McMahon FJ, Tullai J, Kroon D, Freedy J, Zivin RA, Mulcahy LS, Jolliffe LK.

Chem Biol. 1997 Dec;4(12):939-50.

20.

Increased potency of an erythropoietin peptide mimetic through covalent dimerization.

Wrighton NC, Balasubramanian P, Barbone FP, Kashyap AK, Farrell FX, Jolliffe LK, Barrett RW, Dower WJ.

Nat Biotechnol. 1997 Nov;15(12):1261-5.

PMID:
9359108
21.

Small peptides as potent mimetics of the protein hormone erythropoietin.

Wrighton NC, Farrell FX, Chang R, Kashyap AK, Barbone FP, Mulcahy LS, Johnson DL, Barrett RW, Jolliffe LK, Dower WJ.

Science. 1996 Jul 26;273(5274):458-64.

PMID:
8662529
22.

Microinjection of Rap2B protein or RNA induces rearrangement of pigment granules in Xenopus oocytes.

Campa MJ, Farrell FX, Lapetina EG, Chang KJ.

Biochem J. 1993 May 15;292 ( Pt 1):231-6.

23.

Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated.

Farrell FX, Yamamoto K, Lapetina EG.

Biochem J. 1993 Jan 15;289 ( Pt 2):349-55.

24.

Rap1b and platelet function.

Lapetina EG, Farrell FX.

Adv Exp Med Biol. 1993;344:49-55. Review. No abstract available.

PMID:
7516114
25.

Partial purification of a GTPase-activating protein for rap2b from bovine brain membranes.

Farrell FX, Lapetina EG.

Biochem Biophys Res Commun. 1992 Dec 15;189(2):717-21.

PMID:
1472043
26.

RAP2B: a RAS-related GTP-binding protein from platelets.

Ohmstede CA, Farrell FX, Reep BR, Clemetson KJ, Lapetina EG.

Proc Natl Acad Sci U S A. 1990 Sep;87(17):6527-31.

27.

cDNA sequence of a new ras-related gene (rap2b) isolated from human platelets with sequence homology to rap2.

Farrell FX, Ohmstede CA, Reep BR, Lapetina EG.

Nucleic Acids Res. 1990 Jul 25;18(14):4281. No abstract available.

28.

Regulation of vimentin gene expression in the ocular lens.

Sax CM, Farrell FX, Zehner ZE, Piatigorsky J.

Dev Biol. 1990 May;139(1):56-64.

PMID:
2328840
29.

A negative element involved in vimentin gene expression.

Farrell FX, Sax CM, Zehner ZE.

Mol Cell Biol. 1990 May;10(5):2349-58.

30.
31.

Multiple elements are required for expression of an intermediate filament gene.

Sax CM, Farrell FX, Tobian JA, Zehner ZE.

Nucleic Acids Res. 1988 Aug 25;16(16):8057-76.

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