Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 47

1.

Site-Specific Cleavage by Topoisomerase 2: A Mark of the Core Centromere.

Mills WE, Spence JM, Fukagawa T, Farr CJ.

Int J Mol Sci. 2018 Feb 10;19(2). pii: E534. doi: 10.3390/ijms19020534.

2.

The α isoform of topoisomerase II is required for hypercompaction of mitotic chromosomes in human cells.

Farr CJ, Antoniou-Kourounioti M, Mimmack ML, Volkov A, Porter AC.

Nucleic Acids Res. 2014 Apr;42(7):4414-26. doi: 10.1093/nar/gku076. Epub 2014 Jan 29.

3.

Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα.

Samejima K, Samejima I, Vagnarelli P, Ogawa H, Vargiu G, Kelly DA, de Lima Alves F, Kerr A, Green LC, Hudson DF, Ohta S, Cooke CA, Farr CJ, Rappsilber J, Earnshaw WC.

J Cell Biol. 2012 Nov 26;199(5):755-70. doi: 10.1083/jcb.201202155. Epub 2012 Nov 19.

4.

Histone modifications within the human X centromere region.

Mravinac B, Sullivan LL, Reeves JW, Yan CM, Kopf KS, Farr CJ, Schueler MG, Sullivan BA.

PLoS One. 2009 Aug 12;4(8):e6602. doi: 10.1371/journal.pone.0006602.

5.

Studying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells.

Johnson M, Phua HH, Bennett SC, Spence JM, Farr CJ.

Nucleic Acids Res. 2009 Aug;37(14):e98. doi: 10.1093/nar/gkp480. Epub 2009 Jun 3.

6.

Trf1 is not required for proliferation or functional telomere maintenance in chicken DT40 cells.

Cooley C, Baird KM, Faure V, Wenner T, Stewart JL, Modino S, Slijepcevic P, Farr CJ, Morrison CG.

Mol Biol Cell. 2009 May;20(10):2563-71. doi: 10.1091/mbc.E08-10-1019. Epub 2009 Mar 25.

7.

Condensin regulates the stiffness of vertebrate centromeres.

Ribeiro SA, Gatlin JC, Dong Y, Joglekar A, Cameron L, Hudson DF, Farr CJ, McEwen BF, Salmon ED, Earnshaw WC, Vagnarelli P.

Mol Biol Cell. 2009 May;20(9):2371-80. doi: 10.1091/mbc.E08-11-1127. Epub 2009 Mar 4.

8.

Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids.

Park CC, Ahn S, Bloom JS, Lin A, Wang RT, Wu T, Sekar A, Khan AH, Farr CJ, Lusis AJ, Leahy RM, Lange K, Smith DJ.

Nat Genet. 2008 Apr;40(4):421-9. doi: 10.1038/ng.113. Epub 2008 Mar 23. Erratum in: Nat Genet. 2008 May;40(5):682.

9.

Ku70 prevents genome instability resulting from heterozygosity of the telomerase RNA component in a vertebrate tumour line.

Faure V, Wenner T, Cooley C, Bourke E, Farr CJ, Takeda S, Morrison CG.

DNA Repair (Amst). 2008 May 3;7(5):713-24. doi: 10.1016/j.dnarep.2008.01.008. Epub 2008 Mar 4.

PMID:
18308646
10.

Depletion of topoisomerase IIalpha leads to shortening of the metaphase interkinetochore distance and abnormal persistence of PICH-coated anaphase threads.

Spence JM, Phua HH, Mills W, Carpenter AJ, Porter AC, Farr CJ.

J Cell Sci. 2007 Nov 15;120(Pt 22):3952-64. Epub 2007 Oct 23.

11.

Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis.

Vagnarelli P, Hudson DF, Ribeiro SA, Trinkle-Mulcahy L, Spence JM, Lai F, Farr CJ, Lamond AI, Earnshaw WC.

Nat Cell Biol. 2006 Oct;8(10):1133-42. Epub 2006 Sep 24.

12.

The organization and function of chromosomes.

Baird DM, Farr CJ.

EMBO Rep. 2006 Apr;7(4):372-6. Epub 2006 Mar 17. No abstract available.

13.

Increased missegregation and chromosome loss with decreasing chromosome size in vertebrate cells.

Spence JM, Mills W, Mann K, Huxley C, Farr CJ.

Chromosoma. 2006 Feb;115(1):60-74. Epub 2005 Nov 3.

PMID:
16267674
14.

Topoisomerase II cleavage activity within the human D11Z1 and DXZ1 alpha-satellite arrays.

Spence JM, Fournier RE, Oshimura M, Regnier V, Farr CJ.

Chromosome Res. 2005;13(6):637-48. Epub 2005 Sep 21.

PMID:
16170628
15.

Topoisomerase II: untangling its contribution at the centromere.

Porter AC, Farr CJ.

Chromosome Res. 2004;12(6):569-83. Review.

PMID:
15289664
16.

Centromeres, kinetochores and the segregation of chromosomes. Foreword.

Farr CJ.

Chromosome Res. 2004;12(6):517-20. Review. No abstract available.

PMID:
15289659
17.

Chromosome-based vectors for Mammalian cells: an overview.

Lim HN, Farr CJ.

Methods Mol Biol. 2004;240:167-86. Review. No abstract available.

PMID:
14970410
18.

Construction and integration of radiation-hybrid and cytogenetic maps of dog Chromosome X.

Spriggs HF, Holmes NG, Breen MG, Deloukas PG, Langford CF, Ross MT, Carter NP, Davis ME, Knights CE, Smith AE, Farr CJ, McCarthy LC, Binns MM.

Mamm Genome. 2003 Mar;14(3):214-21.

PMID:
12647244
19.

Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array.

Spence JM, Critcher R, Ebersole TA, Valdivia MM, Earnshaw WC, Fukagawa T, Farr CJ.

EMBO J. 2002 Oct 1;21(19):5269-80.

20.

A bovine whole-genome radiation hybrid panel and outline map.

Williams JL, Eggen A, Ferretti L, Farr CJ, Gautier M, Amati G, Ball G, Caramorr T, Critcher R, Costa S, Hextall P, Hills D, Jeulin A, Kiguwa SL, Ross O, Smith AL, Saunier K, Urquhart B, Waddington D.

Mamm Genome. 2002 Aug;13(8):469-74.

PMID:
12226714
21.

Mouse transferrin receptor 1 is the cell entry receptor for mouse mammary tumor virus.

Ross SR, Schofield JJ, Farr CJ, Bucan M.

Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12386-90. Epub 2002 Sep 6.

22.

Chromosome engineering: prospects for gene therapy.

Grimes BR, Warburton PE, Farr CJ.

Gene Ther. 2002 Jun;9(11):713-8.

23.

Protein tyrosine phosphatase genes downregulated in melanoma.

McArdle L, Rafferty M, Maelandsmo GM, Bergin O, Farr CJ, Dervan PA, O'Loughlin S, Herlyn M, Easty DJ.

J Invest Dermatol. 2001 Nov;117(5):1255-60.

24.

All's well that ends well.

Stewart JL, Baird KM, Farr CJ.

Trends Cell Biol. 2001 Jul;11(7):279-80.

PMID:
11413022
25.

Assignment of TERF1 to chicken chromosome 2q32 and TERF2 to chicken microchromosome 11 by fluorescence in situ hybridization.

Fillon V, Critcher R, Baird KM, Konrad JP, Vignal A, Farr CJ.

Cytogenet Cell Genet. 2001;92(1-2):175-6. No abstract available.

PMID:
11306824
26.
27.

A horse whole-genome-radiation hybrid panel: chromosome 1 and 10 preliminary maps.

Kiguwa SL, Hextall P, Smith AL, Critcher R, Swinburne J, Millon L, Binns MM, Goodfellow PN, McCarthy LC, Farr CJ, Oakenfull EA.

Mamm Genome. 2000 Sep;11(9):803-5. No abstract available.

PMID:
10967144
28.

Cloning and characterisation of the chicken gene encoding the telomeric protein TRF2.

Konrad JP, Mills W, Easty DJ, Farr CJ.

Gene. 1999 Oct 18;239(1):81-90.

PMID:
10571037
29.
30.

Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3.

Critcher R, Stitson RN, Wade-Martins R, Easty DJ, Farr CJ.

Cytogenet Cell Genet. 1998;81(3-4):294-5. No abstract available.

PMID:
9730625
31.

Direct cloning and analysis of DNA sequences from a region of the Chinese hamster genome associated with aphidicolin-sensitive fragility.

Palin AH, Critcher R, Fitzgerald DJ, Anderson JN, Farr CJ.

J Cell Sci. 1998 Jun;111 ( Pt 12):1623-34.

32.

Generation of a human X-derived minichromosome using telomere-associated chromosome fragmentation.

Farr CJ, Bayne RA, Kipling D, Mills W, Critcher R, Cooke HJ.

EMBO J. 1995 Nov 1;14(21):5444-54.

33.

Protein B61 as a new growth factor: expression of B61 and up-regulation of its receptor epithelial cell kinase during melanoma progression.

Easty DJ, Guthrie BA, Maung K, Farr CJ, Lindberg RA, Toso RJ, Herlyn M, Bennett DC.

Cancer Res. 1995 Jun 15;55(12):2528-32.

34.

The high mobility group transcription factor, SOX4, transactivates the human CD2 enhancer.

Wotton D, Lake RA, Farr CJ, Owen MJ.

J Biol Chem. 1995 Mar 31;270(13):7515-22.

35.

Sandwiching of a gene within 12 kb of a functional telomere and alpha satellite does not result in silencing.

Bayne RA, Broccoli D, Taggart MH, Thomson EJ, Farr CJ, Cooke HJ.

Hum Mol Genet. 1994 Apr;3(4):539-46.

PMID:
8069295
36.

Novel and known protein tyrosine kinases and their abnormal expression in human melanoma.

Easty DJ, Ganz SE, Farr CJ, Lai C, Herlyn M, Bennett DC.

J Invest Dermatol. 1993 Nov;101(5):679-84.

37.

Genetic maps.

Goodfellow PN, Sefton L, Farr CJ.

Philos Trans R Soc Lond B Biol Sci. 1993 Feb 27;339(1288):139-46. Review.

PMID:
8097046
38.

Characterization and mapping of the human SOX4 gene.

Farr CJ, Easty DJ, Ragoussis J, Collignon J, Lovell-Badge R, Goodfellow PN.

Mamm Genome. 1993;4(10):577-84.

PMID:
8268656
39.

Telomere-associated chromosome fragmentation: applications in genome manipulation and analysis.

Farr CJ, Stevanovic M, Thomson EJ, Goodfellow PN, Cooke HJ.

Nat Genet. 1992 Dec;2(4):275-82.

PMID:
1303279
40.

Hidden messages in genetic maps.

Farr CJ, Goodfellow PN.

Science. 1992 Oct 2;258(5079):49. No abstract available.

PMID:
1439767
41.
42.

DNA fingerprinting. New variations on the theme.

Farr CJ, Goodfellow PN.

Nature. 1991 Nov 21;354(6350):184. No abstract available.

PMID:
1683683
43.

Ras genes and acute myeloid leukaemia.

Toksoz D, Farr CJ, Marshall CJ.

Br J Haematol. 1989 Jan;71(1):1-6. Review. No abstract available.

PMID:
2644966
44.

A study of ras gene mutations in colonic adenomas from familial polyposis coli patients.

Farr CJ, Marshall CJ, Easty DJ, Wright NA, Powell SC, Paraskeva C.

Oncogene. 1988 Dec;3(6):673-8.

PMID:
2577869
45.

Activated ras oncogenes in human thyroid cancers.

Lemoine NR, Mayall ES, Wyllie FS, Farr CJ, Hughes D, Padua RA, Thurston V, Williams ED, Wynford-Thomas D.

Cancer Res. 1988 Aug 15;48(16):4459-63.

46.

Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes.

Farr CJ, Saiki RK, Erlich HA, McCormick F, Marshall CJ.

Proc Natl Acad Sci U S A. 1988 Mar;85(5):1629-33.

47.

ras gene activation in a minor proportion of the blast population in acute myeloid leukemia.

Toksoz D, Farr CJ, Marshall CJ.

Oncogene. 1987;1(4):409-13.

PMID:
3330783

Supplemental Content

Support Center