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The Lymphatic Endothelial mCLCA1 Antibody Induces Proliferation and Growth of Lymph Node Lymphatic Sinuses.

Jordan-Williams KL, Ramanujam N, Farr AG, Ruddell A.

PLoS One. 2016 May 25;11(5):e0156079. doi: 10.1371/journal.pone.0156079. eCollection 2016.


Lymphatic endothelial murine chloride channel calcium-activated 1 is a ligand for leukocyte LFA-1 and Mac-1.

Furuya M, Kirschbaum SB, Paulovich A, Pauli BU, Zhang H, Alexander JS, Farr AG, Ruddell A.

J Immunol. 2010 Nov 15;185(10):5769-77. doi: 10.4049/jimmunol.1002226. Epub 2010 Oct 11.


Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation.

Cohen JN, Guidi CJ, Tewalt EF, Qiao H, Rouhani SJ, Ruddell A, Farr AG, Tung KS, Engelhard VH.

J Exp Med. 2010 Apr 12;207(4):681-8. doi: 10.1084/jem.20092465. Epub 2010 Mar 22.


Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin.

Dumortier A, Durham AD, Di Piazza M, Vauclair S, Koch U, Ferrand G, Ferrero I, Demehri S, Song LL, Farr AG, Leonard WJ, Kopan R, Miele L, Hohl D, Finke D, Radtke F.

PLoS One. 2010 Feb 18;5(2):e9258. doi: 10.1371/journal.pone.0009258.


Visualization and identification of IL-7 producing cells in reporter mice.

Mazzucchelli RI, Warming S, Lawrence SM, Ishii M, Abshari M, Washington AV, Feigenbaum L, Warner AC, Sims DJ, Li WQ, Hixon JA, Gray DH, Rich BE, Morrow M, Anver MR, Cherry J, Naf D, Sternberg LR, McVicar DW, Farr AG, Germain RN, Rogers K, Jenkins NA, Copeland NG, Durum SK.

PLoS One. 2009 Nov 10;4(11):e7637. doi: 10.1371/journal.pone.0007637.


Lessons from thymic epithelial heterogeneity: FoxN1 and tissue-restricted gene expression by extrathymic, endodermally derived epithelium.

Dooley J, Erickson M, Farr AG.

J Immunol. 2009 Oct 15;183(8):5042-9. doi: 10.4049/jimmunol.0901371. Epub 2009 Sep 28.


Differentiation of regulatory Foxp3+ T cells in the thymic cortex.

Liston A, Nutsch KM, Farr AG, Lund JM, Rasmussen JP, Koni PA, Rudensky AY.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11903-8. doi: 10.1073/pnas.0801506105. Epub 2008 Aug 11.


Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.

Demehri S, Liu Z, Lee J, Lin MH, Crosby SD, Roberts CJ, Grigsby PW, Miner JH, Farr AG, Kopan R.

PLoS Biol. 2008 May 27;6(5):e123. doi: 10.1371/journal.pbio.0060123.


A mechanism for the initiation of allergen-induced T helper type 2 responses.

Sokol CL, Barton GM, Farr AG, Medzhitov R.

Nat Immunol. 2008 Mar;9(3):310-8. doi: 10.1038/ni1558.


FGFR2IIIb signaling regulates thymic epithelial differentiation.

Dooley J, Erickson M, Larochelle WJ, Gillard GO, Farr AG.

Dev Dyn. 2007 Dec;236(12):3459-71.


Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice.

Chappaz S, Flueck L, Farr AG, Rolink AG, Finke D.

Blood. 2007 Dec 1;110(12):3862-70. Epub 2007 Aug 16.


Lack of Foxp3 function and expression in the thymic epithelium.

Liston A, Farr AG, Chen Z, Benoist C, Mathis D, Manley NR, Rudensky AY.

J Exp Med. 2007 Mar 19;204(3):475-80. Epub 2007 Mar 12.


Thymic stromal lymphopoietin transgenic mice develop cryoglobulinemia and hepatitis with similarities to human hepatitis C liver disease.

Kowalewska J, Mühlfeld AS, Hudkins KL, Yeh MM, Farr AG, Ravetch JV, Alpers CE.

Am J Pathol. 2007 Mar;170(3):981-9.


Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation.

Gillard GO, Dooley J, Erickson M, Peltonen L, Farr AG.

J Immunol. 2007 Mar 1;178(5):3007-15.


A VEGF165-induced phenotypic switch from increased vessel density to increased vessel diameter and increased endothelial NOS activity.

Parsons-Wingerter P, Chandrasekharan UM, McKay TL, Radhakrishnan K, DiCorleto PE, Albarran B, Farr AG.

Microvasc Res. 2006 Nov;72(3):91-100. Epub 2006 Jul 26.


Cervical thymus in the mouse.

Dooley J, Erickson M, Gillard GO, Farr AG.

J Immunol. 2006 Jun 1;176(11):6484-90.


Developmental regulation of Foxp3 expression during ontogeny.

Fontenot JD, Dooley JL, Farr AG, Rudensky AY.

J Exp Med. 2005 Oct 3;202(7):901-6.


The absence of platelet-derived growth factor-B in circulating cells promotes immune and inflammatory responses in atherosclerosis-prone ApoE-/- mice.

Tang J, Kozaki K, Farr AG, Martin PJ, Lindahl P, Betsholtz C, Raines EW.

Am J Pathol. 2005 Sep;167(3):901-12.


Nude thymic rudiment lacking functional foxn1 resembles respiratory epithelium.

Dooley J, Erickson M, Roelink H, Farr AG.

Dev Dyn. 2005 Aug;233(4):1605-12.


Contrasting models of promiscuous gene expression by thymic epithelium.

Gillard GO, Farr AG.

J Exp Med. 2005 Jul 4;202(1):15-9. Epub 2005 Jun 27. Review.


Regulatory T cell lineage specification by the forkhead transcription factor foxp3.

Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY.

Immunity. 2005 Mar;22(3):329-41.


Cutting edge: TCR revision occurs in germinal centers.

Cooper CJ, Turk GL, Sun M, Farr AG, Fink PJ.

J Immunol. 2004 Dec 1;173(11):6532-6.


Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.

Lehar SM, Dooley J, Farr AG, Bevan MJ.

Blood. 2005 Feb 15;105(4):1440-7. Epub 2004 Oct 14.


Overexpression of complement inhibitor Crry does not prevent cryoglobulin-associated membranoproliferative glomerulonephritis.

Mühlfeld AS, Segerer S, Hudkins K, Farr AG, Bao L, Kraus D, Holers VM, Quigg RJ, Alpers CE.

Kidney Int. 2004 Apr;65(4):1214-23.


Deletion of the fcgamma receptor IIb in thymic stromal lymphopoietin transgenic mice aggravates membranoproliferative glomerulonephritis.

Mühlfeld AS, Segerer S, Hudkins K, Carling MD, Wen M, Farr AG, Ravetch JV, Alpers CE.

Am J Pathol. 2003 Sep;163(3):1127-36.


Growth factor expression in a murine model of cryoglobulinemia.

Taneda S, Hudkins KL, Cui Y, Farr AG, Alpers CE, Segerer S.

Kidney Int. 2003 Feb;63(2):576-90.


Regulation of thymic epithelium by keratinocyte growth factor.

Erickson M, Morkowski S, Lehar S, Gillard G, Beers C, Dooley J, Rubin JS, Rudensky A, Farr AG.

Blood. 2002 Nov 1;100(9):3269-78.


Oral interferon-alpha treatment of mice with cryoglobulinemic glomerulonephritis.

Segerer S, Hudkins KL, Taneda S, Wen M, Cui Y, Segerer M, Farr AG, Alpers CE.

Am J Kidney Dis. 2002 Apr;39(4):876-88.


Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin-mediated signal transduction.

Isaksen DE, Baumann H, Zhou B, Nivollet S, Farr AG, Levin SD, Ziegler SF.

J Immunol. 2002 Apr 1;168(7):3288-94.


Cryoglobulinemic glomerulonephritis in thymic stromal lymphopoietin transgenic mice.

Taneda S, Segerer S, Hudkins KL, Cui Y, Wen M, Segerer M, Wener MH, Khairallah CG, Farr AG, Alpers CE.

Am J Pathol. 2001 Dec;159(6):2355-69.


T cell selection and differential activation on structurally related HLA-DR4 ligands.

Gebe JA, Novak EJ, Kwok WW, Farr AG, Nepom GT, Buckner JH.

J Immunol. 2001 Sep 15;167(6):3250-6.


Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin.

Pandey A, Ozaki K, Baumann H, Levin SD, Puel A, Farr AG, Ziegler SF, Leonard WJ, Lodish HF.

Nat Immunol. 2000 Jul;1(1):59-64.


Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse.

Luther SA, Tang HL, Hyman PL, Farr AG, Cyster JG.

Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12694-9.


Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor.

Park LS, Martin U, Garka K, Gliniak B, Di Santo JP, Muller W, Largaespada DA, Copeland NG, Jenkins NA, Farr AG, Ziegler SF, Morrissey PJ, Paxton R, Sims JE.

J Exp Med. 2000 Sep 4;192(5):659-70.


Thymic vasculature: organizer of the medullary epithelial compartment?

Anderson M, Anderson SK, Farr AG.

Int Immunol. 2000 Jul;12(7):1105-10.


Fibroblast growth factor-2 selectively stimulates angiogenesis of small vessels in arterial tree.

Parsons-Wingerter P, Elliott KE, Clark JI, Farr AG.

Arterioscler Thromb Vasc Biol. 2000 May;20(5):1250-6.


Generational analysis reveals that TGF-beta1 inhibits the rate of angiogenesis in vivo by selective decrease in the number of new vessels.

Parsons-Wingerter P, Elliott KE, Farr AG, Radhakrishnan K, Clark JI, Sage EH.

Microvasc Res. 2000 Mar;59(2):221-32.


A role for pref-1 and HES-1 in thymocyte development.

Kaneta M, Osawa M, Sudo K, Nakauchi H, Farr AG, Takahama Y.

J Immunol. 2000 Jan 1;164(1):256-64.


Abnormal thymic expression of epithelial cell adhesion molecule (EP-CAM) in New Zealand Black (NZB) mice.

Taguchi N, Hashimoto Y, Naiki M, Farr AG, Boyd RL, Ansari AA, Shultz LD, Kotzin BL, Dorshkind K, Ikehara S, Gershwin ME.

J Autoimmun. 1999 Dec;13(4):393-404.


Requirement for stat5 in thymic stromal lymphopoietin-mediated signal transduction.

Isaksen DE, Baumann H, Trobridge PA, Farr AG, Levin SD, Ziegler SF.

J Immunol. 1999 Dec 1;163(11):5971-7.


Anergic CD8+ T cells can persist and function in vivo.

Blish CA, Dillon SR, Farr AG, Fink PJ.

J Immunol. 1999 Jul 1;163(1):155-64.


Dopamine beta-hydroxylase deficiency impairs cellular immunity.

Alaniz RC, Thomas SA, Perez-Melgosa M, Mueller K, Farr AG, Palmiter RD, Wilson CB.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2274-8.


Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism.

Levin SD, Koelling RM, Friend SL, Isaksen DE, Ziegler SF, Perlmutter RM, Farr AG.

J Immunol. 1999 Jan 15;162(2):677-83.


Thymic lymphoproliferative disease after successful correction of CD40 ligand deficiency by gene transfer in mice.

Brown MP, Topham DJ, Sangster MY, Zhao J, Flynn KJ, Surman SL, Woodland DL, Doherty PC, Farr AG, Pattengale PK, Brenner MK.

Nat Med. 1998 Nov;4(11):1253-60.


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