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Items: 1 to 50 of 157

1.

Antibody-mediated inhibition of FXIIa blocks downstream bradykinin generation.

Cao H, Biondo M, Lioe H, Busfield S, Rayzman V, Nieswandt B, Bork K, Harrison LC, Auyeung P, Farkas H, Csuka D, Pelzing M, Dower S, Wilson MJ, Nash A, Nolte MW, Panousis C.

J Allergy Clin Immunol. 2018 Jun 21. pii: S0091-6749(18)30901-1. doi: 10.1016/j.jaci.2018.06.014. [Epub ahead of print]

PMID:
29936101
2.

Icatibant for the treatment of hereditary angioedema with C1-inhibitor deficiency in adolescents and in children aged over 2 years.

Farkas H, Kőhalmi KV.

Expert Rev Clin Immunol. 2018 Jun;14(6):447-460. doi: 10.1080/1744666X.2018.1476851. Epub 2018 May 24.

PMID:
29757016
3.

Targeted next-generation sequencing for the molecular diagnosis of hereditary angioedema due to C1-inhibitor deficiency.

Loules G, Zamanakou M, Parsopoulou F, Vatsiou S, Psarros F, Csuka D, Porebski G, Obtulowicz K, Valerieva A, Staevska M, López-Lera A, López-Trascasa M, Moldovan D, Magerl M, Maurer M, Speletas M, Farkas H, Germenis AE.

Gene. 2018 Aug 15;667:76-82. doi: 10.1016/j.gene.2018.05.029. Epub 2018 May 16.

PMID:
29753808
4.

Idiopathic Nonhistaminergic Acquired Angioedema Versus Hereditary Angioedema.

Andrási N, Veszeli N, Kőhalmi KV, Csuka D, Temesszentandrási G, Varga L, Farkas H.

J Allergy Clin Immunol Pract. 2018 Apr 30. pii: S2213-2198(18)30295-2. doi: 10.1016/j.jaip.2018.04.018. [Epub ahead of print]

PMID:
29715562
5.

Evaluation of avoralstat, an oral kallikrein inhibitor, in a Phase 3 hereditary angioedema prophylaxis trial: The OPuS-2 study.

Riedl MA, Aygören-Pürsün E, Baker J, Farkas H, Anderson J, Bernstein JA, Bouillet L, Busse P, Manning M, Magerl M, Gompels M, Huissoon AP, Longhurst H, Lumry W, Ritchie B, Shapiro R, Soteres D, Banerji A, Cancian M, Johnston DT, Craig TJ, Launay D, Li HH, Liebhaber M, Nickel T, Offenberger J, Rae W, Schrijvers R, Triggiani M, Wedner HJ, Dobo S, Cornpropst M, Clemons D, Fang L, Collis P, Sheridan WP, Maurer M.

Allergy. 2018 Apr 24. doi: 10.1111/all.13466. [Epub ahead of print]

PMID:
29688579
6.

Health-Related Quality of Life with Subcutaneous C1-Inhibitor for Prevention of Attacks of Hereditary Angioedema.

Lumry WR, Craig T, Zuraw B, Longhurst H, Baker J, Li HH, Bernstein JA, Anderson J, Riedl MA, Manning ME, Keith PK, Levy DS, Caballero T, Banerji A, Gower RG, Farkas H, Lawo JP, Pragst I, Machnig T, Watson DJ.

J Allergy Clin Immunol Pract. 2018 Jan 31. pii: S2213-2198(18)30033-3. doi: 10.1016/j.jaip.2017.12.039. [Epub ahead of print]

7.

The international WAO/EAACI guideline for the management of hereditary angioedema-The 2017 revision and update.

Maurer M, Magerl M, Ansotegui I, Aygören-Pürsün E, Betschel S, Bork K, Bowen T, Balle Boysen H, Farkas H, Grumach AS, Hide M, Katelaris C, Lockey R, Longhurst H, Lumry WR, Martinez-Saguer I, Moldovan D, Nast A, Pawankar R, Potter P, Riedl M, Ritchie B, Rosenwasser L, Sánchez-Borges M, Zhi Y, Zuraw B, Craig T.

Allergy. 2018 Aug;73(8):1575-1596. doi: 10.1111/all.13384. Epub 2018 Mar 12.

PMID:
29318628
8.

Investigational drugs in phase I and phase II clinical trials for hereditary angioedema.

Farkas H, Debreczeni ML, Kőhalmi KV.

Expert Opin Investig Drugs. 2018 Jan;27(1):87-103. doi: 10.1080/13543784.2018.1415325. Epub 2017 Dec 15. Review.

PMID:
29226721
9.

Pharmacological Management of Hereditary Angioedema with C1-Inhibitor Deficiency in Pediatric Patients.

Farkas H.

Paediatr Drugs. 2018 Apr;20(2):135-151. doi: 10.1007/s40272-017-0273-x. Review.

PMID:
29214395
10.

Genetic Determinants of C1 Inhibitor Deficiency Angioedema Age of Onset.

Gianni P, Loules G, Zamanakou M, Kompoti M, Csuka D, Psarros F, Magerl M, Moldovan D, Maurer M, Speletas MG, Farkas H, Germenis AE.

Int Arch Allergy Immunol. 2017;174(3-4):200-204. doi: 10.1159/000481987. Epub 2017 Nov 9.

PMID:
29130992
11.

Complete kinetic follow-up of symptoms and complement parameters during a hereditary angioedema attack.

Veszeli N, Kőhalmi KV, Kajdácsi E, Gulyás D, Temesszentandrási G, Cervenak L, Farkas H, Varga L.

Allergy. 2018 Feb;73(2):516-520. doi: 10.1111/all.13327. Epub 2017 Oct 30.

PMID:
28986975
12.

Cleaved kininogen as a biomarker for bradykinin release in hereditary angioedema.

Hofman ZLM, de Maat S, Suffritti C, Zanichelli A, van Doorn C, Sebastian SAE, Veszeli N, Csuka D, Renné T, Pasterkamp G, Cicardi M, Farkas H, Hack CE, Maas C.

J Allergy Clin Immunol. 2017 Dec;140(6):1700-1703.e8. doi: 10.1016/j.jaci.2017.07.012. Epub 2017 Aug 4. No abstract available.

PMID:
28782632
13.

[Effect of danazol treatment on growth in pediatric patients with hereditary angioedema due to C1-inhibitor deficiency].

Kőhalmi KV, Veszeli N, Luczay A, Varga L, Farkas H.

Orv Hetil. 2017 Aug;158(32):1269-1276. doi: 10.1556/650.2017.30806. Hungarian.

PMID:
28780879
14.

The relationship between anxiety and quality of life in children with hereditary angioedema.

Kessel A, Farkas H, Kivity S, Veszeli N, Kőhalmi KV, Engel-Yeger B.

Pediatr Allergy Immunol. 2017 Nov;28(7):692-698. doi: 10.1111/pai.12758. Epub 2017 Aug 11.

PMID:
28692169
15.

Treatment Effect and Safety of Icatibant in Pediatric Patients with Hereditary Angioedema.

Farkas H, Reshef A, Aberer W, Caballero T, McCarthy L, Hao J, Nothaft W, Schranz J, Bernstein JA, Li HH.

J Allergy Clin Immunol Pract. 2017 Nov - Dec;5(6):1671-1678.e2. doi: 10.1016/j.jaip.2017.04.010. Epub 2017 Jun 7.

16.

The role of the complement system in hereditary angioedema.

Csuka D, Veszeli N, Varga L, Prohászka Z, Farkas H.

Mol Immunol. 2017 Sep;89:59-68. doi: 10.1016/j.molimm.2017.05.020. Epub 2017 Jun 7. Review.

PMID:
28595743
17.

A novel prophylaxis with C1-inhibitor concentrate in hereditary angioedema during erythema marginatum.

Kőhalmi KV, Veszeli N, Cervenak L, Varga L, Farkas H.

Immunol Lett. 2017 Sep;189:90-93. doi: 10.1016/j.imlet.2017.05.015. Epub 2017 May 31.

PMID:
28577900
18.

Prevention of Hereditary Angioedema Attacks with a Subcutaneous C1 Inhibitor.

Longhurst H, Cicardi M, Craig T, Bork K, Grattan C, Baker J, Li HH, Reshef A, Bonner J, Bernstein JA, Anderson J, Lumry WR, Farkas H, Katelaris CH, Sussman GL, Jacobs J, Riedl M, Manning ME, Hebert J, Keith PK, Kivity S, Neri S, Levy DS, Baeza ML, Nathan R, Schwartz LB, Caballero T, Yang W, Crisan I, Hernandez MD, Hussain I, Tarzi M, Ritchie B, Králíčková P, Guilarte M, Rehman SM, Banerji A, Gower RG, Bensen-Kennedy D, Edelman J, Feuersenger H, Lawo JP, Machnig T, Pawaskar D, Pragst I, Zuraw BL; COMPACT Investigators.

N Engl J Med. 2017 Mar 23;376(12):1131-1140. doi: 10.1056/NEJMoa1613627.

19.

Reply.

Joseph K, Constantino-Silva RN, Grumach AS, Feldweg A, Wright L, Frank N, Vuzman D, Sharma R, Suffritti C, Cicardi M, Varga L, Farkas H, Bork K, Kaplan AP.

J Allergy Clin Immunol. 2017 May;139(5):1720-1721. doi: 10.1016/j.jaci.2016.12.983. Epub 2017 Mar 16. No abstract available.

PMID:
28318557
20.

Health-related quality of life among children with hereditary angioedema.

Engel-Yeger B, Farkas H, Kivity S, Veszeli N, Kőhalmi KV, Kessel A.

Pediatr Allergy Immunol. 2017 Jun;28(4):370-376. doi: 10.1111/pai.12712. Epub 2017 Apr 4.

PMID:
28258590
21.

Glucocorticoid receptor gene polymorphisms in hereditary angioedema with C1-inhibitor deficiency.

Zotter Z, Nagy Z, Patócs A, Csuka D, Veszeli N, Kőhalmi KV, Farkas H.

Orphanet J Rare Dis. 2017 Jan 10;12(1):5. doi: 10.1186/s13023-016-0552-6.

22.

Assessment of inhibitory antibodies in patients with hereditary angioedema treated with plasma-derived C1 inhibitor.

Farkas H, Varga L, Moldovan D, Obtulowicz K, Shirov T, Machnig T, Feuersenger H, Edelman J, Williams-Herman D, Rojavin M.

Ann Allergy Asthma Immunol. 2016 Nov;117(5):508-513. doi: 10.1016/j.anai.2016.08.025. Epub 2016 Oct 24.

23.

Bacteriuria increases the risk of edematous attacks in hereditary angioedema with C1-inhibitor deficiency.

Zotter Z, Veszeli N, Kőhalmi KV, Varga L, Imreh É, Kovács G, Nallbani M, Farkas H.

Allergy. 2016 Dec;71(12):1791-1793. doi: 10.1111/all.13034. Epub 2016 Sep 15.

PMID:
27548887
24.

International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1 inhibitor deficiency.

Farkas H, Martinez-Saguer I, Bork K, Bowen T, Craig T, Frank M, Germenis AE, Grumach AS, Luczay A, Varga L, Zanichelli A; HAWK.

Allergy. 2017 Feb;72(2):300-313. doi: 10.1111/all.13001. Epub 2016 Sep 8.

25.

Thyroid hormones and complement parameters in hereditary angioedema with C1-inhibitor deficiency.

Czaller I, Csuka D, Zotter Z, Veszeli N, Takács E, Imreh É, Varga L, Farkas H.

Ann Allergy Asthma Immunol. 2016 Aug;117(2):175-9. doi: 10.1016/j.anai.2016.06.005. Epub 2016 Jun 28.

PMID:
27364943
26.

"Nuts and Bolts" of Laboratory Evaluation of Angioedema.

Farkas H, Veszeli N, Kajdácsi E, Cervenak L, Varga L.

Clin Rev Allergy Immunol. 2016 Oct;51(2):140-51. doi: 10.1007/s12016-016-8539-6. Review.

PMID:
27142368
27.

Icatibant as acute treatment for hereditary angioedema in adults.

Farkas H.

Expert Rev Clin Pharmacol. 2016 Jun;9(6):779-88. doi: 10.1080/17512433.2016.1182425. Epub 2016 May 13. Review.

PMID:
27123689
28.

First report of icatibant treatment in a pregnant patient with hereditary angioedema.

Farkas H, Kőhalmi KV, Veszeli N, Tóth F, Varga L.

J Obstet Gynaecol Res. 2016 Aug;42(8):1026-8. doi: 10.1111/jog.13003. Epub 2016 Apr 19.

PMID:
27093898
29.

Psychometric Field Study of Hereditary Angioedema Quality of Life Questionnaire for Adults: HAE-QoL.

Prior N, Remor E, Pérez-Fernández E, Caminoa M, Gómez-Traseira C, Gayá F, Aabom A, Aberer W, Betschel S, Boccon-Gibod I, Bouillet L, Bygum A, Csuka D, Farkas H, Gomide M, Grumach A, Leibovich I, Malbran A, Moldovan D, Mihaly E, Obtulowicz K, Perpén C, Peveling-Oberhag A, Porebski G, Chavannes CR, Reshef A, Staubach P, Wiednig M, Caballero T.

J Allergy Clin Immunol Pract. 2016 May-Jun;4(3):464-473.e4. doi: 10.1016/j.jaip.2015.12.010. Epub 2016 Mar 8.

PMID:
26969268
30.

Atrial natriuretic peptide as a novel biomarker of hereditary angioedema.

Kajdácsi E, Varga L, Prohászka Z, Farkas H, Cervenak L.

Clin Immunol. 2016 Apr;165:45-6. doi: 10.1016/j.clim.2016.03.007. Epub 2016 Mar 4. No abstract available.

PMID:
26960949
31.

The effect of long-term danazol treatment on haematological parameters in hereditary angioedema.

Kőhalmi KV, Veszeli N, Zotter Z, Csuka D, Benedek S, Imreh É, Varga L, Farkas H.

Orphanet J Rare Dis. 2016 Feb 25;11:18. doi: 10.1186/s13023-016-0386-2.

32.

Novel Vasoregulatory Aspects of Hereditary Angioedema: the Role of Arginine Vasopressin, Adrenomedullin and Endothelin-1.

Kajdácsi E, Jani PK, Csuka D, Varga L, Prohászka Z, Farkas H, Cervenak L.

J Clin Immunol. 2016 Feb;36(2):160-70. doi: 10.1007/s10875-016-0239-8. Epub 2016 Feb 12.

PMID:
26873707
33.

Risk of thromboembolism in patients with hereditary angioedema treated with plasma-derived C1-inhibitor.

Farkas H, Kőhalmi KV, Veszeli N, Zotter Z, Várnai K, Varga L.

Allergy Asthma Proc. 2016 Mar-Apr;37(2):164-70. doi: 10.2500/aap.2016.37.3933. Epub 2016 Jan 21.

PMID:
26802388
34.

Erythema Marginatum as an Early Symptom of Hereditary Angioedema: Case Report of 2 Newborns.

Martinez-Saguer I, Farkas H.

Pediatrics. 2016 Feb;137(2):e20152411. doi: 10.1542/peds.2015-2411. Epub 2016 Jan 12.

35.

[WAO Guideline for the Management of Hereditary Angioedema].

Craig T, Pürsün EA, Bork K, Bowen T, Boysen H, Farkas H, Grumach A, Katelaris CH, Lockey R, Longhurst H, Lumry W, Magerl M, Martinez-Saguer I, Ritchie B, Nast A, Pawankar R, Zuraw B, Maurer M.

Arerugi. 2015 Sep;64(9):1215-41. doi: 10.15036/arerugi.64.1215. Japanese. No abstract available.

PMID:
26657910
36.

Neutrophil activation during attacks in patients with hereditary angioedema due to C1-inhibitor deficiency.

Veszeli N, Csuka D, Zotter Z, Imreh É, Józsi M, Benedek S, Varga L, Farkas H.

Orphanet J Rare Dis. 2015 Dec 10;10:156. doi: 10.1186/s13023-015-0374-y.

37.

Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases.

Hollingsworth TD, Adams ER, Anderson RM, Atkins K, Bartsch S, Basáñez MG, Behrend M, Blok DJ, Chapman LA, Coffeng L, Courtenay O, Crump RE, de Vlas SJ, Dobson A, Dyson L, Farkas H, Galvani AP, Gambhir M, Gurarie D, Irvine MA, Jervis S, Keeling MJ, Kelly-Hope L, King C, Lee BY, Le Rutte EA, Lietman TM, Ndeffo-Mbah M, Medley GF, Michael E, Pandey A, Peterson JK, Pinsent A, Porco TC, Richardus JH, Reimer L, Rock KS, Singh BK, Stolk W, Swaminathan S, Torr SJ, Townsend J, Truscott J, Walker M, Zoueva A; NTD Modelling Consortium.

Parasit Vectors. 2015 Dec 9;8:630. doi: 10.1186/s13071-015-1235-1.

38.

Icatibant for Multiple Hereditary Angioedema Attacks across the Controlled and Open-Label Extension Phases of FAST-3.

Lumry WR, Farkas H, Moldovan D, Toubi E, Baptista J, Craig T, Riedl M.

Int Arch Allergy Immunol. 2015;168(1):44-55. doi: 10.1159/000441060. Epub 2015 Nov 11.

39.

Comprehensive study into the activation of the plasma enzyme systems during attacks of hereditary angioedema due to C1-inhibitor deficiency.

Csuka D, Veszeli N, Imreh É, Zotter Z, Skopál J, Prohászka Z, Varga L, Farkas H.

Orphanet J Rare Dis. 2015 Oct 9;10:132. doi: 10.1186/s13023-015-0351-5.

40.

The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema.

Hansen CB, Csuka D, Munthe-Fog L, Varga L, Farkas H, Hansen KM, Koch C, Skjødt K, Garred P, Skjoedt MO.

J Immunol. 2015 Oct 15;195(8):3596-604. doi: 10.4049/jimmunol.1402838. Epub 2015 Sep 14.

41.

F12-46C/T polymorphism as modifier of the clinical phenotype of hereditary angioedema.

Speletas M, Szilágyi Á, Csuka D, Koutsostathis N, Psarros F, Moldovan D, Magerl M, Kompoti M, Varga L, Maurer M, Farkas H, Germenis AE.

Allergy. 2015 Dec;70(12):1661-4. doi: 10.1111/all.12714. Epub 2015 Aug 26.

PMID:
26248961
42.

Frequency of the virilising effects of attenuated androgens reported by women with hereditary angioedema.

Zotter Z, Veszeli N, Csuka D, Varga L, Farkas H.

Orphanet J Rare Dis. 2014 Dec 5;9:205. doi: 10.1186/s13023-014-0205-6.

43.

Successful prophylaxis with recombinant human C1 inhibitor in a patient with hereditary angioedema.

Farkas H, Kohalmi KV, Veszeli N, Zotter Z, Varga L.

Ann Allergy Asthma Immunol. 2015 Jan;114(1):64-5. doi: 10.1016/j.anai.2014.10.002. Epub 2014 Nov 6. No abstract available.

PMID:
25454013
44.

Diagnosis and treatment of bradykinin-mediated angioedema: outcomes from an angioedema expert consensus meeting.

Craig TJ, Bernstein JA, Farkas H, Bouillet L, Boccon-Gibod I.

Int Arch Allergy Immunol. 2014;165(2):119-27. doi: 10.1159/000368404. Epub 2014 Nov 15.

45.

Canadian hereditary angioedema guideline.

Betschel S, Badiou J, Binkley K, Hébert J, Kanani A, Keith P, Lacuesta G, Yang B, Aygören-Pürsün E, Bernstein J, Bork K, Caballero T, Cicardi M, Craig T, Farkas H, Longhurst H, Zuraw B, Boysen H, Borici-Mazi R, Bowen T, Dallas K, Dean J, Lang-Robertson K, Laramée B, Leith E, Mace S, McCusker C, Moote B, Poon MC, Ritchie B, Stark D, Sussman G, Waserman S.

Allergy Asthma Clin Immunol. 2014 Oct 24;10(1):50. doi: 10.1186/1710-1492-10-50. eCollection 2014.

46.

Hereditary angioedema: molecular and clinical differences among European populations.

Speletas M, Szilagyi A, Psarros F, Moldovan D, Magerl M, Kompoti M, Gramoustianou E, Bors A, Mihaly E, Tordai A, Avramouli A, Varga L, Maurer M, Farkas H, Germenis AE.

J Allergy Clin Immunol. 2015 Feb;135(2):570-3. doi: 10.1016/j.jaci.2014.08.007. Epub 2014 Sep 23. No abstract available.

PMID:
25258140
47.

Common genetic variants of the human steroid 21-hydroxylase gene (CYP21A2) are related to differences in circulating hormone levels.

Doleschall M, Szabó JA, Pázmándi J, Szilágyi Á, Koncz K, Farkas H, Tóth M, Igaz P, Gláz E, Prohászka Z, Korbonits M, Rácz K, Füst G, Patócs A.

PLoS One. 2014 Sep 11;9(9):e107244. doi: 10.1371/journal.pone.0107244. eCollection 2014.

48.

A novel assay to diagnose hereditary angioedema utilizing inhibition of bradykinin-forming enzymes.

Joseph K, Bains S, Tholanikunnel BG, Bygum A, Aabom A, Koch C, Farkas H, Varga L, Ghebrehiwet B, Kaplan AP.

Allergy. 2015 Jan;70(1):115-9. doi: 10.1111/all.12520. Epub 2014 Oct 15.

PMID:
25186184
49.

A three-year follow-up study of the development of joint contractures in 131 patients with systemic sclerosis.

Bálint Z, Farkas H, Farkas N, Minier T, Kumánovics G, Horváth K, Solyom AI, Czirják L, Varjú C.

Clin Exp Rheumatol. 2014 Nov-Dec;32(6 Suppl 86):S-68-74. Epub 2014 Aug 4.

PMID:
25152080
50.

Activation of the ficolin-lectin pathway during attacks of hereditary angioedema.

Csuka D, Munthe-Fog L, Hein E, Zotter Z, Prohászka Z, Farkas H, Varga L, Garred P.

J Allergy Clin Immunol. 2014 Dec;134(6):1388-1393.e1. doi: 10.1016/j.jaci.2014.05.030. Epub 2014 Jul 16.

PMID:
25042985

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