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Items: 1 to 50 of 90

1.

The novel ghrelin receptor inverse agonist PF-5190457 administered with alcohol: preclinical safety experiments and a phase 1b human laboratory study.

Lee MR, Tapocik JD, Ghareeb M, Schwandt ML, Dias AA, Le AN, Cobbina E, Farinelli LA, Bouhlal S, Farokhnia M, Heilig M, Akhlaghi F, Leggio L.

Mol Psychiatry. 2018 May 4. doi: 10.1038/s41380-018-0064-y. [Epub ahead of print]

PMID:
29728704
2.

Roles of Non-Coding RNA in Sugarcane-Microbe Interaction.

Thiebaut F, Rojas CA, Grativol C, Calixto EPDR, Motta MR, Ballesteros HGF, Peixoto B, de Lima BNS, Vieira LM, Walter ME, de Armas EM, Entenza JOP, Lifschitz S, Farinelli L, Hemerly AS, Ferreira PCG.

Noncoding RNA. 2017 Dec 20;3(4). pii: E25. doi: 10.3390/ncrna3040025.

3.

Fibrocartilaginous metaplasia identified in the long head of the biceps brachii.

Bottegoni C, Farinelli L, Aquili A, Manzotti S, Baldini M, Gigante A.

J Shoulder Elbow Surg. 2018 Jul;27(7):1221-1225. doi: 10.1016/j.jse.2018.02.042. Epub 2018 Mar 19.

PMID:
29567036
4.

Small RNA-Omics for Virome Reconstruction and Antiviral Defense Characterization in Mixed Infections of Cultivated Solanum Plants.

Turco S, Golyaev V, Seguin J, Gilli C, Farinelli L, Boller T, Schumpp O, Pooggin MM.

Mol Plant Microbe Interact. 2018 Jul;31(7):707-723. doi: 10.1094/MPMI-12-17-0301-R. Epub 2018 May 10.

PMID:
29424662
5.

Ultra-low input transcriptomics reveal the spore functional content and phylogenetic affiliations of poorly studied arbuscular mycorrhizal fungi.

Beaudet D, Chen ECH, Mathieu S, Yildirir G, Ndikumana S, Dalpé Y, Séguin S, Farinelli L, Stajich JE, Corradi N.

DNA Res. 2018 Apr 1;25(2):217-227. doi: 10.1093/dnares/dsx051.

6.

Low number of fixed somatic mutations in a long-lived oak tree.

Schmid-Siegert E, Sarkar N, Iseli C, Calderon S, Gouhier-Darimont C, Chrast J, Cattaneo P, Schütz F, Farinelli L, Pagni M, Schneider M, Voumard J, Jaboyedoff M, Fankhauser C, Hardtke CS, Keller L, Pannell JR, Reymond A, Robinson-Rechavi M, Xenarios I, Reymond P.

Nat Plants. 2017 Dec;3(12):926-929. doi: 10.1038/s41477-017-0066-9. Epub 2017 Dec 4.

PMID:
29209081
7.

The effect of anti-IgE therapy in knee osteoarthritis: a pilot observational study.

Aquili A, Farinelli L, Bottegoni C, Antonicelli L, Gigante A.

J Biol Regul Homeost Agents. 2017 Oct-Dec,;31(4 Suppl. 1):1-5.

PMID:
29172299
8.

Revisiting the Roles of Tobamovirus Replicase Complex Proteins in Viral Replication and Silencing Suppression.

Malpica-López N, Rajeswaran R, Beknazariants D, Seguin J, Golyaev V, Farinelli L, Pooggin MM.

Mol Plant Microbe Interact. 2018 Jan;31(1):125-144. doi: 10.1094/MPMI-07-17-0164-R. Epub 2017 Nov 15.

PMID:
29140168
9.

Exogenous ghrelin administration increases alcohol self-administration and modulates brain functional activity in heavy-drinking alcohol-dependent individuals.

Farokhnia M, Grodin EN, Lee MR, Oot EN, Blackburn AN, Stangl BL, Schwandt ML, Farinelli LA, Momenan R, Ramchandani VA, Leggio L.

Mol Psychiatry. 2017 Nov 14. doi: 10.1038/mp.2017.226. [Epub ahead of print]

PMID:
29133954
10.

Biobehavioral effects of baclofen in anxious alcohol-dependent individuals: a randomized, double-blind, placebo-controlled, laboratory study.

Farokhnia M, Schwandt ML, Lee MR, Bollinger JW, Farinelli LA, Amodio JP, Sewell L, Lionetti TA, Spero DE, Leggio L.

Transl Psychiatry. 2017 Apr 25;7(4):e1108. doi: 10.1038/tp.2017.71.

11.

Rapid adaptation drives invasion of airway donor microbiota by Pseudomonas after lung transplantation.

Beaume M, Köhler T, Greub G, Manuel O, Aubert JD, Baerlocher L, Farinelli L, Buckling A, van Delden C; Swiss Transplant Cohort Study.

Sci Rep. 2017 Jan 17;7:40309. doi: 10.1038/srep40309.

12.

Technical Insights into Highly Sensitive Isolation and Molecular Characterization of Fixed and Live Circulating Tumor Cells for Early Detection of Tumor Invasion.

Laget S, Broncy L, Hormigos K, Dhingra DM, BenMohamed F, Capiod T, Osteras M, Farinelli L, Jackson S, Paterlini-Bréchot P.

PLoS One. 2017 Jan 6;12(1):e0169427. doi: 10.1371/journal.pone.0169427. eCollection 2017.

13.

Homologous platelet-rich plasma for the treatment of knee involvement in primary Sjögren’s syndrome.

Bottegoni C, Farinelli L, Aquili A, Chiurazzi E, Gigante A.

J Biol Regul Homeost Agents. 2016 Oct-Dec;30(4 Suppl 1):63-67.

PMID:
28002901
14.

Microbial Communities of Conducting and Respiratory Zones of Lung-Transplanted Patients.

Beaume M, Lazarevic V, Köhler T, Gaïa N, Manuel O, Aubert JD, Baerlocher L, Farinelli L, Gasche P, Schrenzel J, van Delden C; Swiss Transplant Cohort Study.

Front Microbiol. 2016 Nov 7;7:1749. eCollection 2016.

15.

Human tissue engineering allows the identification of active miRNA regulators of glioblastoma aggressiveness.

Cosset E, Petty T, Dutoit V, Tirefort D, Otten-Hernandez P, Farinelli L, Dietrich PY, Preynat-Seauve O.

Biomaterials. 2016 Nov;107:74-87. doi: 10.1016/j.biomaterials.2016.08.009. Epub 2016 Aug 24.

PMID:
27614160
16.

Evidence for the sexual origin of heterokaryosis in arbuscular mycorrhizal fungi.

Ropars J, Toro KS, Noel J, Pelin A, Charron P, Farinelli L, Marton T, Krüger M, Fuchs J, Brachmann A, Corradi N.

Nat Microbiol. 2016 Mar 21;1(6):16033. doi: 10.1038/nmicrobiol.2016.33.

PMID:
27572831
17.

Cell-free DNA testing of an extended range of chromosomal anomalies: clinical experience with 6,388 consecutive cases.

Pescia G, Guex N, Iseli C, Brennan L, Osteras M, Xenarios I, Farinelli L, Conrad B.

Genet Med. 2017 Feb;19(2):169-175. doi: 10.1038/gim.2016.72. Epub 2016 Jun 30.

18.

The Bee Microbiome: Impact on Bee Health and Model for Evolution and Ecology of Host-Microbe Interactions.

Engel P, Kwong WK, McFrederick Q, Anderson KE, Barribeau SM, Chandler JA, Cornman RS, Dainat J, de Miranda JR, Doublet V, Emery O, Evans JD, Farinelli L, Flenniken ML, Granberg F, Grasis JA, Gauthier L, Hayer J, Koch H, Kocher S, Martinson VG, Moran N, Munoz-Torres M, Newton I, Paxton RJ, Powell E, Sadd BM, Schmid-Hempel P, Schmid-Hempel R, Song SJ, Schwarz RS, vanEngelsdorp D, Dainat B.

MBio. 2016 Apr 26;7(2):e02164-15. doi: 10.1128/mBio.02164-15. Review.

19.

MISIS-2: A bioinformatics tool for in-depth analysis of small RNAs and representation of consensus master genome in viral quasispecies.

Seguin J, Otten P, Baerlocher L, Farinelli L, Pooggin MM.

J Virol Methods. 2016 Jul;233:37-40. doi: 10.1016/j.jviromet.2016.03.005. Epub 2016 Mar 16.

PMID:
26994965
20.

Unusual RNA plant virus integration in the soybean genome leads to the production of small RNAs.

da Fonseca GC, de Oliveira LFV, de Morais GL, Abdelnor RV, Nepomuceno AL, Waterhouse PM, Farinelli L, Margis R.

Plant Sci. 2016 May;246:62-69. doi: 10.1016/j.plantsci.2016.01.011. Epub 2016 Feb 11.

PMID:
26993236
21.

The genome of an Encephalitozoon cuniculi type III strain reveals insights into the genetic diversity and mode of reproduction of a ubiquitous vertebrate pathogen.

Pelin A, Moteshareie H, Sak B, Selman M, Naor A, Eyahpaise MÈ, Farinelli L, Golshani A, Kvac M, Corradi N.

Heredity (Edinb). 2016 May;116(5):458-65. doi: 10.1038/hdy.2016.4. Epub 2016 Feb 3.

22.

Field Trial and Molecular Characterization of RNAi-Transgenic Tomato Plants That Exhibit Resistance to Tomato Yellow Leaf Curl Geminivirus.

Fuentes A, Carlos N, Ruiz Y, Callard D, Sánchez Y, Ochagavía ME, Seguin J, Malpica-López N, Hohn T, Lecca MR, Pérez R, Doreste V, Rehrauer H, Farinelli L, Pujol M, Pooggin MM.

Mol Plant Microbe Interact. 2016 Mar;29(3):197-209. doi: 10.1094/MPMI-08-15-0181-R. Epub 2016 Feb 11.

23.

Corrigendum: Domains of genome-wide gene expression dysregulation in Down's syndrome.

Letourneau A, Santoni FA, Bonilla X, Sailani MR, Gonzalez D, Kind J, Chevalier C, Thurman R, Sandstrom RS, Hibaoui Y, Garieri M, Popadin K, Falconnet E, Gagnebin M, Gehrig C, Vannier A, Guipponi M, Farinelli L, Robyr D, Migliavacca E, Borel C, Deutsch S, Feki A, Stamatoyannopoulos JA, Herault Y, van Steensel B, Guigo R, Antonarakis SE.

Nature. 2016 Mar 17;531(7594):400. doi: 10.1038/nature16135. Epub 2015 Dec 2. No abstract available.

PMID:
26633627
24.

Embryonic gene expression of Coregonus palaea (whitefish) under pathogen stress as analyzed by high-throughput RNA-sequencing.

Wilkins LG, Clark ES, Farinelli L, Wedekind C, Fumagalli L.

Fish Shellfish Immunol. 2015 Nov;47(1):130-40. doi: 10.1016/j.fsi.2015.08.035. Epub 2015 Sep 2.

PMID:
26340848
25.

Genome analyses suggest the presence of polyploidy and recent human-driven expansions in eight global populations of the honeybee pathogen Nosema ceranae.

Pelin A, Selman M, Aris-Brosou S, Farinelli L, Corradi N.

Environ Microbiol. 2015 Nov;17(11):4443-58. doi: 10.1111/1462-2920.12883. Epub 2015 Jun 11.

PMID:
25914091
26.

bacterial infection drives the expression dynamics of microRNAs and their isomiRs.

Siddle KJ, Tailleux L, Deschamps M, Loh YH, Deluen C, Gicquel B, Antoniewski C, Barreiro LB, Farinelli L, Quintana-Murci L.

PLoS Genet. 2015 Mar 20;11(3):e1005064. doi: 10.1371/journal.pgen.1005064. eCollection 2015 Mar. Erratum in: PLoS Genet. 2015 Jun;11(6):e1005321.

27.

Sequencing and characterizing the genome of Estrella lausannensis as an undergraduate project: training students and biological insights.

Bertelli C, Aeby S, Chassot B, Clulow J, Hilfiker O, Rappo S, Ritzmann S, Schumacher P, Terrettaz C, Benaglio P, Falquet L, Farinelli L, Gharib WH, Goesmann A, Harshman K, Linke B, Miyazaki R, Rivolta C, Robinson-Rechavi M, van der Meer JR, Greub G.

Front Microbiol. 2015 Feb 19;6:101. doi: 10.3389/fmicb.2015.00101. eCollection 2015.

28.

Genome-wide identification of microRNA and siRNA responsive to endophytic beneficial diazotrophic bacteria in maize.

Thiebaut F, Rojas CA, Grativol C, Motta MR, Vieira T, Regulski M, Martienssen RA, Farinelli L, Hemerly AS, Ferreira PC.

BMC Genomics. 2014 Sep 6;15:766. doi: 10.1186/1471-2164-15-766.

29.

Interactions of Rice tungro bacilliform pararetrovirus and its protein P4 with plant RNA-silencing machinery.

Rajeswaran R, Golyaev V, Seguin J, Zvereva AS, Farinelli L, Pooggin MM.

Mol Plant Microbe Interact. 2014 Dec;27(12):1370-8. doi: 10.1094/MPMI-07-14-0201-R.

30.

Whole-Genome Shotgun Sequence of Arthrospira platensis Strain Paraca, a Cultivated and Edible Cyanobacterium.

Lefort F, Calmin G, Crovadore J, Falquet J, Hurni JP, Osteras M, Haldemann F, Farinelli L.

Genome Announc. 2014 Aug 7;2(4). pii: e00751-14. doi: 10.1128/genomeA.00751-14.

31.

Evasion of short interfering RNA-directed antiviral silencing in Musa acuminata persistently infected with six distinct banana streak pararetroviruses.

Rajeswaran R, Seguin J, Chabannes M, Duroy PO, Laboureau N, Farinelli L, Iskra-Caruana ML, Pooggin MM.

J Virol. 2014 Oct;88(19):11516-28. doi: 10.1128/JVI.01496-14. Epub 2014 Jul 23.

32.

Genome and transcriptome sequencing identifies breeding targets in the orphan crop tef (Eragrostis tef).

Cannarozzi G, Plaza-Wüthrich S, Esfeld K, Larti S, Wilson YS, Girma D, de Castro E, Chanyalew S, Blösch R, Farinelli L, Lyons E, Schneider M, Falquet L, Kuhlemeier C, Assefa K, Tadele Z.

BMC Genomics. 2014 Jul 9;15:581. doi: 10.1186/1471-2164-15-581.

33.

Sugarcane genome sequencing by methylation filtration provides tools for genomic research in the genus Saccharum.

Grativol C, Regulski M, Bertalan M, McCombie WR, da Silva FR, Zerlotini Neto A, Vicentini R, Farinelli L, Hemerly AS, Martienssen RA, Ferreira PC.

Plant J. 2014 Jul;79(1):162-72. doi: 10.1111/tpj.12539. Epub 2014 Jun 17.

34.

Domains of genome-wide gene expression dysregulation in Down's syndrome.

Letourneau A, Santoni FA, Bonilla X, Sailani MR, Gonzalez D, Kind J, Chevalier C, Thurman R, Sandstrom RS, Hibaoui Y, Garieri M, Popadin K, Falconnet E, Gagnebin M, Gehrig C, Vannier A, Guipponi M, Farinelli L, Robyr D, Migliavacca E, Borel C, Deutsch S, Feki A, Stamatoyannopoulos JA, Herault Y, van Steensel B, Guigo R, Antonarakis SE.

Nature. 2014 Apr 17;508(7496):345-50. doi: 10.1038/nature13200. Erratum in: Nature. 2016 Mar 17;531(7594):400.

PMID:
24740065
35.

Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice.

Gapp K, Jawaid A, Sarkies P, Bohacek J, Pelczar P, Prados J, Farinelli L, Miska E, Mansuy IM.

Nat Neurosci. 2014 May;17(5):667-9. doi: 10.1038/nn.3695. Epub 2014 Apr 13.

36.

Duality of the murine CD8 compartment.

Genolet R, Leignadier J, Østerås M, Farinelli L, Stevenson BJ, Luescher IF.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E1007-15. doi: 10.1073/pnas.1317847111. Epub 2014 Mar 4.

37.

A genomic perspective on a new bacterial genus and species from the Alcaligenaceae family, Basilea psittacipulmonis.

Whiteson KL, Hernandez D, Lazarevic V, Gaia N, Farinelli L, François P, Pilo P, Frey J, Schrenzel J.

BMC Genomics. 2014 Mar 1;15:169. doi: 10.1186/1471-2164-15-169.

38.

De novo reconstruction of consensus master genomes of plant RNA and DNA viruses from siRNAs.

Seguin J, Rajeswaran R, Malpica-López N, Martin RR, Kasschau K, Dolja VV, Otten P, Farinelli L, Pooggin MM.

PLoS One. 2014 Feb 11;9(2):e88513. doi: 10.1371/journal.pone.0088513. eCollection 2014.

39.

Whole-Genome Shotgun Sequence of Bacillus amyloliquefaciens Strain UASWS BA1, a Bacterium Antagonistic to Plant Pathogenic Fungi.

Lefort F, Calmin G, Pelleteret P, Farinelli L, Osteras M, Crovadore J.

Genome Announc. 2014 Feb 6;2(1). pii: e00016-14. doi: 10.1128/genomeA.00016-14.

40.

Comprehensive metagenomic analysis of glioblastoma reveals absence of known virus despite antiviral-like type I interferon gene response.

Cosset É, Petty TJ, Dutoit V, Cordey S, Padioleau I, Otten-Hernandez P, Farinelli L, Kaiser L, Bruyère-Cerdan P, Tirefort D, Amar El-Dusouqui S, Nayernia Z, Krause KH, Zdobnov EM, Dietrich PY, Rigal E, Preynat-Seauve O.

Int J Cancer. 2014 Sep 15;135(6):1381-9. doi: 10.1002/ijc.28670. Epub 2014 May 8.

41.

MISIS: a bioinformatics tool to view and analyze maps of small RNAs derived from viruses and genomic loci generating multiple small RNAs.

Seguin J, Otten P, Baerlocher L, Farinelli L, Pooggin MM.

J Virol Methods. 2014 Jan;195:120-2. doi: 10.1016/j.jviromet.2013.10.013. Epub 2013 Oct 14.

PMID:
24134945
42.

De novo finished 2.8 Mbp Staphylococcus aureus genome assembly from 100 bp short and long range paired-end reads.

Hernandez D, Tewhey R, Veyrieras JB, Farinelli L, Østerås M, François P, Schrenzel J.

Bioinformatics. 2014 Jan 1;30(1):40-9. doi: 10.1093/bioinformatics/btt590. Epub 2013 Oct 15.

PMID:
24130309
43.

Extreme diversification of the mating type-high-mobility group (MATA-HMG) gene family in a plant-associated arbuscular mycorrhizal fungus.

Riley R, Charron P, Idnurm A, Farinelli L, Dalpé Y, Martin F, Corradi N.

New Phytol. 2014 Jan;201(1):254-68. doi: 10.1111/nph.12462. Epub 2013 Aug 27.

44.

Analysis of the Elodea nuttallii transcriptome in response to mercury and cadmium pollution: development of sensitive tools for rapid ecotoxicological testing.

Regier N, Baerlocher L, Münsterkötter M, Farinelli L, Cosio C.

Environ Sci Technol. 2013 Aug 6;47(15):8825-34. doi: 10.1021/es401082h. Epub 2013 Jul 25.

PMID:
23802634
45.

Re: Errors in the editorial by Christensen and Giovannoni [HERVs: have we been here before? MSJ 18(12) 1670-1672].

Perron H, Germi R, Bernard C, Garcia-Montojo M, Deluen C, Farinelli L, Faucard R, Veas F, Stefas I, Fabriek BO, Van-Horssen J, Vander-Valk P, Gerdil C, Mancuso R, Saresella M, Clerici M, Marcel S, Creange A, Cavaretta R, Caputo D, Arru G, Morand P, Lang AB, Sotgiu S, Ruprecht K, Rieckmann P, Villoslada P, Chofflon M, Boucraut J, Pelletier J, Hartung HP.

Mult Scler. 2013 May;19(6):831-2. doi: 10.1177/1352458513485150. No abstract available.

PMID:
23658240
46.

Multiplex targeted high-throughput sequencing for Mendelian cardiac disorders.

Fokstuen S, Makrythanasis P, Nikolaev S, Santoni F, Robyr D, Munoz A, Bevillard J, Farinelli L, Iseli C, Antonarakis SE, Blouin JL.

Clin Genet. 2014 Apr;85(4):365-70. doi: 10.1111/cge.12168. Epub 2013 May 13.

PMID:
23590259
47.

Whole-Genome Shotgun Sequence of Pseudomonas viridiflava, a Bacterium Species Pathogenic to Ararabidopsis thaliana.

Lefort F, Calmin G, Crovadore J, Osteras M, Farinelli L.

Genome Announc. 2013 Jan;1(1). pii: e00116-12. doi: 10.1128/genomeA.00116-12. Epub 2013 Jan 24.

48.

Extremely reduced levels of heterozygosity in the vertebrate pathogen Encephalitozoon cuniculi.

Selman M, Sak B, Kváč M, Farinelli L, Weiss LM, Corradi N.

Eukaryot Cell. 2013 Apr;12(4):496-502. doi: 10.1128/EC.00307-12. Epub 2013 Feb 2.

49.

Highly diverse TCRα chain repertoire of pre-immune CD8⁺ T cells reveals new insights in gene recombination.

Genolet R, Stevenson BJ, Farinelli L, Osterås M, Luescher IF.

EMBO J. 2012 Nov 5;31(21):4247-8. doi: 10.1038/emboj.2012.277. No abstract available.

50.

Primary and secondary siRNAs in geminivirus-induced gene silencing.

Aregger M, Borah BK, Seguin J, Rajeswaran R, Gubaeva EG, Zvereva AS, Windels D, Vazquez F, Blevins T, Farinelli L, Pooggin MM.

PLoS Pathog. 2012 Sep;8(9):e1002941. doi: 10.1371/journal.ppat.1002941. Epub 2012 Sep 27.

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