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Items: 1 to 50 of 87

1.

Spanish Cell Therapy Network (TerCel): 15 years of successful collaborative translational research.

Sánchez-Guijo F, García-Olmo D, Prósper F, Martínez S, Zapata A, Fernández-Avilés F, Toledo-Aral JJ, Torres M, Fariñas I, Badimón L, Labandeira-García JL, García-Sancho J, Moraleda JM; TerCel.

Cytotherapy. 2020 Jan;22(1):1-5. doi: 10.1016/j.jcyt.2019.11.001. Epub 2019 Dec 19. Review.

2.

Interaction between Angiotensin Type 1, Type 2, and Mas Receptors to Regulate Adult Neurogenesis in the Brain Ventricular-Subventricular Zone.

Garcia-Garrote M, Perez-Villalba A, Garrido-Gil P, Belenguer G, Parga JA, Perez-Sanchez F, Labandeira-Garcia JL, Fariñas I, Rodriguez-Pallares J.

Cells. 2019 Nov 30;8(12). pii: E1551. doi: 10.3390/cells8121551.

3.

NO Hemodynamic Speed Limit for Hippocampal Neurogenesis.

Morante-Redolat JM, Fariñas I.

Neuron. 2019 Sep 4;103(5):752-754. doi: 10.1016/j.neuron.2019.08.020.

PMID:
31487523
4.

Physiological Interactions between Microglia and Neural Stem Cells in the Adult Subependymal Niche.

Sirerol-Piquer MS, Belenguer G, Morante-Redolat JM, Duart-Abadia P, Perez-Villalba A, Fariñas I.

Neuroscience. 2019 May 1;405:77-91. doi: 10.1016/j.neuroscience.2019.01.009. Epub 2019 Jan 21. Review.

PMID:
30677487
5.

Role of p27Kip1 as a transcriptional regulator.

Bachs O, Gallastegui E, Orlando S, Bigas A, Morante-Redolat JM, Serratosa J, Fariñas I, Aligué R, Pujol MJ.

Oncotarget. 2018 May 25;9(40):26259-26278. doi: 10.18632/oncotarget.25447. eCollection 2018 May 25. Review.

6.

p27Kip1 regulates alpha-synuclein expression.

Gallastegui E, Domuro C, Serratosa J, Larrieux A, Sin L, Martinez J, Besson A, Morante-Redolat JM, Orlando S, Aligue R, Fariñas I, Pujol MJ, Bachs O.

Oncotarget. 2018 Mar 27;9(23):16368-16379. doi: 10.18632/oncotarget.24687. eCollection 2018 Mar 27.

7.

Selective α-Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinson's Disease.

Alarcón-Arís D, Recasens A, Galofré M, Carballo-Carbajal I, Zacchi N, Ruiz-Bronchal E, Pavia-Collado R, Chica R, Ferrés-Coy A, Santos M, Revilla R, Montefeltro A, Fariñas I, Artigas F, Vila M, Bortolozzi A.

Mol Ther. 2018 Feb 7;26(2):550-567. doi: 10.1016/j.ymthe.2017.11.015. Epub 2017 Nov 29.

8.

Synaptic Regulator α-Synuclein in Dopaminergic Fibers Is Essentially Required for the Maintenance of Subependymal Neural Stem Cells.

Perez-Villalba A, Sirerol-Piquer MS, Belenguer G, Soriano-Cantón R, Muñoz-Manchado AB, Villadiego J, Alarcón-Arís D, Soria FN, Dehay B, Bezard E, Vila M, Bortolozzi A, Toledo-Aral JJ, Pérez-Sánchez F, Fariñas I.

J Neurosci. 2018 Jan 24;38(4):814-825. doi: 10.1523/JNEUROSCI.2276-17.2017. Epub 2017 Dec 7.

9.

Building Bridges through Science.

Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, al'Absi M, Arain F, Arango-Lasprilla JC, Atasoy D, Avila J, Badawi A, Bading H, Baig AM, Baleriola J, Belmonte C, Bertocchi I, Betz H, Blakemore C, Blanke O, Boehm-Sturm P, Bonhoeffer T, Bonifazi P, Brose N, Campolongo P, Celikel T, Chang CC, Chang TY, Citri A, Cline HT, Cortes JM, Cullen K, Dean K, Delgado-Garcia JM, Desroches M, Disterhoft JF, Dowling JE, Draguhn A, El-Khamisy SF, El Manira A, Enam SA, Encinas JM, Erramuzpe A, Esteban JA, Fariñas I, Fischer E, Fukunaga I, Gabilondo I, Ganten D, Gidon A, Gomez-Esteban JC, Greengard P, Grinevich V, Gruart A, Guillemin R, Hariri AR, Hassan B, Häusser M, Hayashi Y, Hussain NK, Jabbar AA, Jaber M, Jahn R, Janahi EM, Kabbaj M, Kettenmann H, Kindt M, Knafo S, Köhr G, Komai S, Krugers H, Kuhn B, Ghazal NL, Larkum ME, London M, Lutz B, Matute C, Martinez-Millan L, Maroun M, McGaugh J, Moustafa AA, Nasim A, Nave KA, Neher E, Nikolich K, Outeiro T, Palmer LM, Penagarikano O, Perez-Otano I, Pfaff DW, Poucet B, Rahman AU, Ramos-Cabrer P, Rashidy-Pour A, Roberts RJ, Rodrigues S, Sanes JR, Schaefer AT, Segal M, Segev I, Shafqat S, Siddiqui NA, Soreq H, Soriano-García E, Spanagel R, Sprengel R, Stuart G, Südhof TC, Tønnesen J, Treviño M, Uthman BM, Venter JC, Verkhratsky A, Weiss C, Wiesel TN, Yaksi E, Yizhar O, Young LJ, Young P, Zawia NH, Zugaza JL, Hasan MT.

Neuron. 2017 Nov 15;96(4):730-735. doi: 10.1016/j.neuron.2017.09.028.

10.

Evolutionary conserved role of eukaryotic translation factor eIF5A in the regulation of actin-nucleating formins.

Muñoz-Soriano V, Domingo-Muelas A, Li T, Gamero E, Bizy A, Fariñas I, Alepuz P, Paricio N.

Sci Rep. 2017 Aug 29;7(1):9580. doi: 10.1038/s41598-017-10057-y.

11.

Cyclin-Dependent Kinase 4 Regulates Adult Neural Stem Cell Proliferation and Differentiation in Response to Insulin.

Chirivella L, Kirstein M, Ferrón SR, Domingo-Muelas A, Durupt FC, Acosta-Umanzor C, Cano-Jaimez M, Pérez-Sánchez F, Barbacid M, Ortega S, Burks DJ, Fariñas I.

Stem Cells. 2017 Dec;35(12):2403-2416. doi: 10.1002/stem.2694. Epub 2017 Sep 3.

12.

α-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines.

Martìn-Clemente B, Alvarez-Castelao B, Mayo I, Sierra AB, Díaz V, Milán M, Fariñas I, Gómez-Isla T, Ferrer I, Castaño JG.

J Biol Chem. 2016 Apr 22;291(17):8986. doi: 10.1074/jbc.A116.409028. No abstract available.

13.

Isolation, culture and analysis of adult subependymal neural stem cells.

Belenguer G, Domingo-Muelas A, Ferrón SR, Morante-Redolat JM, Fariñas I.

Differentiation. 2016 Apr-Jun;91(4-5):28-41. doi: 10.1016/j.diff.2016.01.005. Epub 2016 Mar 23. Review.

PMID:
27016251
14.

Fetal neurogenesis: breathe HIF you can.

Morante-Redolat JM, Fariñas I.

EMBO J. 2016 May 2;35(9):901-3. doi: 10.15252/embj.201694238. Epub 2016 Mar 24. No abstract available.

15.
16.

Characterization and isolation of immature neurons of the adult mouse piriform cortex.

Rubio A, Belles M, Belenguer G, Vidueira S, Fariñas I, Nacher J.

Dev Neurobiol. 2016 Jul;76(7):748-63. doi: 10.1002/dneu.22357. Epub 2015 Oct 31.

17.

p73 is required for ependymal cell maturation and neurogenic SVZ cytoarchitecture.

Gonzalez-Cano L, Fuertes-Alvarez S, Robledinos-Anton N, Bizy A, Villena-Cortes A, Fariñas I, Marques MM, Marin MC.

Dev Neurobiol. 2016 Jul;76(7):730-47. doi: 10.1002/dneu.22356. Epub 2015 Oct 31.

18.

Regulation of the p19(Arf)/p53 pathway by histone acetylation underlies neural stem cell behavior in senescence-prone SAMP8 mice.

Soriano-Cantón R, Perez-Villalba A, Morante-Redolat JM, Marqués-Torrejón MÁ, Pallás M, Pérez-Sánchez F, Fariñas I.

Aging Cell. 2015 Jun;14(3):453-62. doi: 10.1111/acel.12328. Epub 2015 Feb 26.

19.

The cyclin-dependent kinase inhibitor p27 kip1 regulates radial stem cell quiescence and neurogenesis in the adult hippocampus.

Andreu Z, Khan MA, González-Gómez P, Negueruela S, Hortigüela R, San Emeterio J, Ferrón SR, Martínez G, Vidal A, Fariñas I, Lie DC, Mira H.

Stem Cells. 2015 Jan;33(1):219-29. doi: 10.1002/stem.1832.

20.

Endothelial NT-3 delivered by vasculature and CSF promotes quiescence of subependymal neural stem cells through nitric oxide induction.

Delgado AC, Ferrón SR, Vicente D, Porlan E, Perez-Villalba A, Trujillo CM, D'Ocón P, Fariñas I.

Neuron. 2014 Aug 6;83(3):572-85. doi: 10.1016/j.neuron.2014.06.015. Epub 2014 Jul 18.

21.

MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin.

Porlan E, Martí-Prado B, Morante-Redolat JM, Consiglio A, Delgado AC, Kypta R, López-Otín C, Kirstein M, Fariñas I.

Nat Cell Biol. 2014 Jul;16(7):629-38. doi: 10.1038/ncb2993. Epub 2014 Jun 22.

PMID:
24952463
22.

The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors.

Eguren M, Porlan E, Manchado E, García-Higuera I, Cañamero M, Fariñas I, Malumbres M.

Nat Commun. 2013;4:2880. doi: 10.1038/ncomms3880.

23.

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.

Recasens A, Dehay B, Bové J, Carballo-Carbajal I, Dovero S, Pérez-Villalba A, Fernagut PO, Blesa J, Parent A, Perier C, Fariñas I, Obeso JA, Bezard E, Vila M.

Ann Neurol. 2014 Mar;75(3):351-62. doi: 10.1002/ana.24066. Epub 2014 Feb 18.

PMID:
24243558
24.

Transcriptional repression of Bmp2 by p21(Waf1/Cip1) links quiescence to neural stem cell maintenance.

Porlan E, Morante-Redolat JM, Marqués-Torrejón MÁ, Andreu-Agulló C, Carneiro C, Gómez-Ibarlucea E, Soto A, Vidal A, Ferrón SR, Fariñas I.

Nat Neurosci. 2013 Nov;16(11):1567-75. doi: 10.1038/nn.3545. Epub 2013 Oct 6.

PMID:
24097040
25.

Cyclin-dependent kinase inhibitor p21 controls adult neural stem cell expansion by regulating Sox2 gene expression.

Marqués-Torrejón MÁ, Porlan E, Banito A, Gómez-Ibarlucea E, Lopez-Contreras AJ, Fernández-Capetillo O, Vidal A, Gil J, Torres J, Fariñas I.

Cell Stem Cell. 2013 Jan 3;12(1):88-100. doi: 10.1016/j.stem.2012.12.001. Epub 2012 Dec 20.

26.

Symmetric expansion of neural stem cells from the adult olfactory bulb is driven by astrocytes via WNT7A.

Moreno-Estellés M, González-Gómez P, Hortigüela R, Díaz-Moreno M, San Emeterio J, Carvalho AL, Fariñas I, Mira H.

Stem Cells. 2012 Dec;30(12):2796-809. doi: 10.1002/stem.1243.

27.

IRS2 signalling is required for the development of a subset of sensory spinal neurons.

Chirivella L, Cano-Jaimez M, Pérez-Sánchez F, Herraez L, Carretero J, Fariñas I, Burks DJ, Kirstein M.

Eur J Neurosci. 2012 Feb;35(3):341-52. doi: 10.1111/j.1460-9568.2011.07959.x.

PMID:
22288475
28.

Postnatal loss of Dlk1 imprinting in stem cells and niche astrocytes regulates neurogenesis.

Ferrón SR, Charalambous M, Radford E, McEwen K, Wildner H, Hind E, Morante-Redolat JM, Laborda J, Guillemot F, Bauer SR, Fariñas I, Ferguson-Smith AC.

Nature. 2011 Jul 20;475(7356):381-5. doi: 10.1038/nature10229.

29.

Regulated segregation of kinase Dyrk1A during asymmetric neural stem cell division is critical for EGFR-mediated biased signaling.

Ferron SR, Pozo N, Laguna A, Aranda S, Porlan E, Moreno M, Fillat C, de la Luna S, Sánchez P, Arbonés ML, Fariñas I.

Cell Stem Cell. 2010 Sep 3;7(3):367-79. doi: 10.1016/j.stem.2010.06.021.

30.

Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus.

Mira H, Andreu Z, Suh H, Lie DC, Jessberger S, Consiglio A, San Emeterio J, Hortigüela R, Marqués-Torrejón MA, Nakashima K, Colak D, Götz M, Fariñas I, Gage FH.

Cell Stem Cell. 2010 Jul 2;7(1):78-89. doi: 10.1016/j.stem.2010.04.016.

31.

Perivascular nerve fiber α-synuclein regulates contractility of mouse aorta: a link to autonomic dysfunction in Parkinson's disease.

Marrachelli VG, Miranda FJ, Alabadí JA, Milán M, Cano-Jaimez M, Kirstein M, Alborch E, Fariñas I, Pérez-Sánchez F.

Neurochem Int. 2010 Jul;56(8):991-8. doi: 10.1016/j.neuint.2010.04.011. Epub 2010 Apr 24.

PMID:
20420875
32.

Prosurvival effect of human wild-type alpha-synuclein on MPTP-induced toxicity to central but not peripheral catecholaminergic neurons isolated from transgenic mice.

Pérez-Sánchez F, Milán M, Buendía P, Cano-Jaimez M, Ambrosio S, Rosenthal A, Fariñas I.

Neuroscience. 2010 May 5;167(2):261-76. doi: 10.1016/j.neuroscience.2010.02.016. Epub 2010 Feb 12.

PMID:
20156526
33.

Vulnerability of peripheral catecholaminergic neurons to MPTP is not regulated by alpha-synuclein.

Cano-Jaimez M, Pérez-Sánchez F, Milán M, Buendía P, Ambrosio S, Fariñas I.

Neurobiol Dis. 2010 Apr;38(1):92-103. doi: 10.1016/j.nbd.2010.01.003. Epub 2010 Jan 15.

PMID:
20079841
34.

BDNF is essentially required for the early postnatal survival of nociceptors.

Valdés-Sánchez T, Kirstein M, Pérez-Villalba A, Vega JA, Fariñas I.

Dev Biol. 2010 Mar 15;339(2):465-76. doi: 10.1016/j.ydbio.2010.01.001. Epub 2010 Jan 11.

35.

Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons.

Martín-Ibáñez R, Crespo E, Urbán N, Sergent-Tanguy S, Herranz C, Jaumot M, Valiente M, Long JE, Pineda JR, Andreu C, Rubenstein JL, Marín O, Georgopoulos K, Mengod G, Fariñas I, Bachs O, Alberch J, Canals JM.

J Comp Neurol. 2010 Feb 1;518(3):329-51. doi: 10.1002/cne.22215.

PMID:
19950118
36.

Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis.

Ferrón SR, Marqués-Torrejón MA, Mira H, Flores I, Taylor K, Blasco MA, Fariñas I.

J Neurosci. 2009 Nov 18;29(46):14394-407. doi: 10.1523/JNEUROSCI.3836-09.2009.

37.

Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor.

Wu HH, Bellmunt E, Scheib JL, Venegas V, Burkert C, Reichardt LF, Zhou Z, Fariñas I, Carter BD.

Nat Neurosci. 2009 Dec;12(12):1534-41. doi: 10.1038/nn.2446. Epub 2009 Nov 15.

38.

Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone.

Andreu-Agulló C, Morante-Redolat JM, Delgado AC, Fariñas I.

Nat Neurosci. 2009 Dec;12(12):1514-23. doi: 10.1038/nn.2437. Epub 2009 Nov 8.

PMID:
19898467
39.

Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation.

Folgueras AR, Valdés-Sánchez T, Llano E, Menéndez L, Baamonde A, Denlinger BL, Belmonte C, Juárez L, Lastra A, García-Suárez O, Astudillo A, Kirstein M, Pendás AM, Fariñas I, López-Otín C.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16451-6. doi: 10.1073/pnas.0908507106. Epub 2009 Sep 4.

40.

Satb2 regulates callosal projection neuron identity in the developing cerebral cortex.

Alcamo EA, Chirivella L, Dautzenberg M, Dobreva G, Fariñas I, Grosschedl R, McConnell SK.

Neuron. 2008 Feb 7;57(3):364-77. doi: 10.1016/j.neuron.2007.12.012.

41.

Cell expression of GDAP1 in the nervous system and pathogenesis of Charcot-Marie-Tooth type 4A disease.

Pedrola L, Espert A, Valdés-Sánchez T, Sánchez-Piris M, Sirkowski EE, Scherer SS, Fariñas I, Palau F.

J Cell Mol Med. 2008 Apr;12(2):679-89. Epub 2007 Nov 16.

42.

A combined ex/in vivo assay to detect effects of exogenously added factors in neural stem cells.

Ferron SR, Andreu-Agullo C, Mira H, Sanchez P, Marques-Torrejon MA, Farinas I.

Nat Protoc. 2007;2(4):849-859.

PMID:
17474182
43.

Abnormal development of pacinian corpuscles in double trkB;trkC knockout mice.

de Carlos F, Cobo J, Germanà G, Silos-Santiago I, Laurà R, Haro JJ, Fariñas I, Vega JA.

Neurosci Lett. 2006 Dec 27;410(3):157-61. Epub 2006 Nov 13.

PMID:
17101216
44.

SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation.

Dobreva G, Chahrour M, Dautzenberg M, Chirivella L, Kanzler B, Fariñas I, Karsenty G, Grosschedl R.

Cell. 2006 Jun 2;125(5):971-86.

45.

Pigment epithelium-derived factor is a niche signal for neural stem cell renewal.

Ramírez-Castillejo C, Sánchez-Sánchez F, Andreu-Agulló C, Ferrón SR, Aroca-Aguilar JD, Sánchez P, Mira H, Escribano J, Fariñas I.

Nat Neurosci. 2006 Mar;9(3):331-9. Epub 2006 Feb 19.

PMID:
16491078
46.

Selective glial cell line-derived neurotrophic factor production in adult dopaminergic carotid body cells in situ and after intrastriatal transplantation.

Villadiego J, Méndez-Ferrer S, Valdés-Sánchez T, Silos-Santiago I, Fariñas I, López-Barneo J, Toledo-Aral JJ.

J Neurosci. 2005 Apr 20;25(16):4091-8.

47.

BDNF, but not NT-4, is necessary for normal development of Meissner corpuscles.

González-Martínez T, Fariñas I, Del Valle ME, Feito J, Germanà G, Cobo J, Vega JA.

Neurosci Lett. 2005 Mar 22;377(1):12-5. Epub 2004 Dec 19.

PMID:
15722178
48.

Stressor-related impairment of synaptic transmission in hippocampal slices from alpha-synuclein knockout mice.

Martín ED, González-García C, Milán M, Fariñas I, Ceña V.

Eur J Neurosci. 2004 Dec;20(11):3085-91.

PMID:
15579163
49.

alpha-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines.

Martìn-Clemente B, Alvarez-Castelao B, Mayo I, Sierra AB, Dìaz V, Milán M, Fariñas I, Gómez-Isla T, Ferrer I, Castaño JG.

J Biol Chem. 2004 Dec 17;279(51):52984-90. Epub 2004 Oct 4. Erratum in: J Biol Chem. 2016 Apr 22;291(17):8986.

50.

Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells.

Ferrón S, Mira H, Franco S, Cano-Jaimez M, Bellmunt E, Ramírez C, Fariñas I, Blasco MA.

Development. 2004 Aug;131(16):4059-70. Epub 2004 Jul 21.

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