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A unique signal sequence of the chemokine receptor CCR7 promotes package into COPII vesicles for efficient receptor trafficking.

Uetz-von Allmen E, Rippl AV, Farhan H, Legler DF.

J Leukoc Biol. 2018 Mar 30. doi: 10.1002/JLB.2VMA1217-492R. [Epub ahead of print]


Crosstalk of Autophagy and the Secretory Pathway and Its Role in Diseases.

Zahoor M, Farhan H.

Int Rev Cell Mol Biol. 2018;337:153-184. doi: 10.1016/bs.ircmb.2017.12.004. Epub 2018 Jan 12.


The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function.

Reiterer V, Figueras-Puig C, Le Guerroue F, Confalonieri S, Vecchi M, Jalapothu D, Kanse SM, Deshaies RJ, Di Fiore PP, Behrends C, Farhan H.

EMBO J. 2018 Mar 15;37(6). pii: e99170. doi: 10.15252/embj.201899170. No abstract available.


Evaluation of the adenosine deaminase (ADA) G22A gene polymorphism with recurrent spontaneous abortion among Egyptian patients.

Farhan HM, Abu-Gabal K, Katta M, Ibrahim R.

Cent Eur J Immunol. 2017;42(3):281-286. doi: 10.5114/ceji.2017.70972. Epub 2017 Oct 30.


Effects of Opioids Given to Facilitate Mechanical Ventilation on Sleep Apnea After Extubation in the Intensive Care Unit.

Timm FP, Zaremba S, Grabitz SD, Farhan HN, Zaremba S, Siliski E, Shin CH, Muse S, Friedrich S, Mojica JE, Kurth T, Ramachandran SK, Eikermann M.

Sleep. 2018 Jan 1;41(1). doi: 10.1093/sleep/zsx191.


The link between autophagy and secretion: a story of multitasking proteins.

Farhan H, Kundu M, Ferro-Novick S.

Mol Biol Cell. 2017 May 1;28(9):1161-1164. doi: 10.1091/mbc.E16-11-0762. Review.


Bio-Zombie: the rise of pseudoenzymes in biology.

Murphy JM, Farhan H, Eyers PA.

Biochem Soc Trans. 2017 Apr 15;45(2):537-544. doi: 10.1042/BST20160400. Review.


STYX: a versatile pseudophosphatase.

Reiterer V, Pawłowski K, Farhan H.

Biochem Soc Trans. 2017 Apr 15;45(2):449-456. doi: 10.1042/BST20160279. Review.


Proper selection of sedative drugs improves outcomes: volatile anesthetics are surgeons' best friends.

Farhan H, Grabitz SD, Ruscic KJ, Eikermann M.

Ann Transl Med. 2017 Mar;5(5):122. doi: 10.21037/atm.2017.02.24. No abstract available.


The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function.

Reiterer V, Figueras-Puig C, Le Guerroue F, Confalonieri S, Vecchi M, Jalapothu D, Kanse SM, Deshaies RJ, Di Fiore PP, Behrends C, Farhan H.

EMBO J. 2017 Feb 1;36(3):260-273. doi: 10.15252/embj.201694795. Epub 2016 Dec 22. Erratum in: EMBO J. 2018 Mar 15;37(6):.


Regulation of EGFR surface levels by COPII-dependent trafficking.

Farhan H.

J Cell Biol. 2016 Nov 21;215(4):441-443. Epub 2016 Nov 8.


Dose-Dependent Protective Effect of Inhalational Anesthetics Against Postoperative Respiratory Complications: A Prospective Analysis of Data on File From Three Hospitals in New England.

Grabitz SD, Farhan HN, Ruscic KJ, Timm FP, Shin CH, Thevathasan T, Staehr-Rye AK, Kurth T, Eikermann M.

Crit Care Med. 2017 Jan;45(1):e30-e39.


Dyslipidaemia in the Middle East: Current status and a call for action.

Al Rasadi K, Almahmeed W, AlHabib KF, Abifadel M, Farhan HA, AlSifri S, Jambart S, Zubaid M, Awan Z, Al-Waili K, Barter P.

Atherosclerosis. 2016 Sep;252:182-187. doi: 10.1016/j.atherosclerosis.2016.07.925. Epub 2016 Jul 30. Review.


Cdc42 and Cellular Polarity: Emerging Roles at the Golgi.

Farhan H, Hsu VW.

Trends Cell Biol. 2016 Apr;26(4):241-248. doi: 10.1016/j.tcb.2015.11.003. Epub 2015 Dec 17. Review.


Alteration of Golgi Structure by Stress: A Link to Neurodegeneration?

Alvarez-Miranda EA, Sinnl M, Farhan H.

Front Neurosci. 2015 Nov 12;9:435. doi: 10.3389/fnins.2015.00435. eCollection 2015.


FIG4 is a hepatitis C virus particle-bound protein implicated in virion morphogenesis and infectivity with cholesteryl ester modulation potential.

Cottarel J, Plissonnier ML, Kullolli M, Pitteri S, Clément S, Millarte V, Si-Ahmed SN, Farhan H, Zoulim F, Parent R.

J Gen Virol. 2016 Jan;97(1):69-81. doi: 10.1099/jgv.0.000331. Epub 2015 Oct 29.


Acquired Muscle Weakness in the Surgical Intensive Care Unit: Nosology, Epidemiology, Diagnosis, and Prevention.

Farhan H, Moreno-Duarte I, Latronico N, Zafonte R, Eikermann M.

Anesthesiology. 2016 Jan;124(1):207-34. doi: 10.1097/ALN.0000000000000874. Review.


TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export.

Stadel D, Millarte V, Tillmann KD, Huber J, Tamin-Yecheskel BC, Akutsu M, Demishtein A, Ben-Zeev B, Anikster Y, Perez F, Dötsch V, Elazar Z, Rogov V, Farhan H, Behrends C.

Mol Cell. 2015 Oct 1;60(1):89-104. doi: 10.1016/j.molcel.2015.09.010.


Endomembrane control of cell polarity: Relevance to cancer.

Baschieri F, Farhan H.

Small GTPases. 2015;6(2):104-7. doi: 10.1080/21541248.2015.1018402. Review.


Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications.

McLean DJ, Diaz-Gil D, Farhan HN, Ladha KS, Kurth T, Eikermann M.

Anesthesiology. 2015 Jun;122(6):1201-13. doi: 10.1097/ALN.0000000000000674.


Phospholipase C γ1 regulates early secretory trafficking and cell migration via interaction with p115.

Millarte V, Boncompain G, Tillmann K, Perez F, Sztul E, Farhan H.

Mol Biol Cell. 2015 Jun 15;26(12):2263-78. doi: 10.1091/mbc.E15-03-0178. Epub 2015 Apr 22.


Loss of GM130 in breast cancer cells and its effects on cell migration, invasion and polarity.

Baschieri F, Uetz-von Allmen E, Legler DF, Farhan H.

Cell Cycle. 2015;14(8):1139-47. doi: 10.1080/15384101.2015.1007771.


Effects of parecoxib on analgesia benefit and blood loss following open prostatectomy: a multicentre randomized trial.

Dirkmann D, Groeben H, Farhan H, Stahl DL, Eikermann M.

BMC Anesthesiol. 2015 Mar 9;15:31. doi: 10.1186/s12871-015-0015-y. eCollection 2015.


Systems biology of the secretory pathway: what have we learned so far?

Farhan H.

Biol Cell. 2015 Jul;107(7):205-17. doi: 10.1111/boc.201400065. Epub 2015 May 6. Review.


CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling.

Genau HM, Huber J, Baschieri F, Akutsu M, Dötsch V, Farhan H, Rogov V, Behrends C.

Mol Cell. 2015 Mar 19;57(6):995-1010. doi: 10.1016/j.molcel.2014.12.040. Epub 2015 Feb 12.


Residual Paralysis: Does it Influence Outcome After Ambulatory Surgery?

Farhan H, Moreno-Duarte I, McLean D, Eikermann M.

Curr Anesthesiol Rep. 2014 Dec;4(4):290-302.


Regulation of Sec16 levels and dynamics links proliferation and secretion.

Tillmann KD, Reiterer V, Baschieri F, Hoffmann J, Millarte V, Hauser MA, Mazza A, Atias N, Legler DF, Sharan R, Weiss M, Farhan H.

J Cell Sci. 2015 Feb 15;128(4):670-82. doi: 10.1242/jcs.157115. Epub 2014 Dec 19.


PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection.

McEwan DG, Richter B, Claudi B, Wigge C, Wild P, Farhan H, McGourty K, Coxon FP, Franz-Wachtel M, Perdu B, Akutsu M, Habermann A, Kirchof A, Helfrich MH, Odgren PR, Van Hul W, Frangakis AS, Rajalingam K, Macek B, Holden DW, Bumann D, Dikic I.

Cell Host Microbe. 2015 Jan 14;17(1):58-71. doi: 10.1016/j.chom.2014.11.011. Epub 2014 Dec 11.


Pattern of acute pancreatitis in a tertiary care center in oman.

Albulushi A, Siddiqi A, Alqarshoubi I, Aladawi M, Alkhadhouri G, Farhan H.

Oman Med J. 2014 Sep;29(5):358-61. doi: 10.5001/omj.2014.94.


The ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and contributes to Salmonella resistance in mice.

Spinnenhirn V, Farhan H, Basler M, Aichem A, Canaan A, Groettrup M.

J Cell Sci. 2014 Nov 15;127(Pt 22):4883-93. doi: 10.1242/jcs.152371. Epub 2014 Sep 30.


Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis.

Baschieri F, Confalonieri S, Bertalot G, Di Fiore PP, Dietmaier W, Leist M, Crespo P, Macara IG, Farhan H.

Nat Commun. 2014 Sep 11;5:4839. doi: 10.1038/ncomms5839.


Trends of indigenous healing among people with psychiatric disorders: comparative study of Arabic and Kurdish ethnicities in Iraq.

Rahim TA, Saeed BA, Farhan HM, Aziz RR.

J Relig Health. 2015 Feb;54(1):316-26. doi: 10.1007/s10943-014-9915-2.


Day of the dead: pseudokinases and pseudophosphatases in physiology and disease.

Reiterer V, Eyers PA, Farhan H.

Trends Cell Biol. 2014 Sep;24(9):489-505. doi: 10.1016/j.tcb.2014.03.008. Epub 2014 May 10. Review.


Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+).

Krug AK, Gutbier S, Zhao L, Pöltl D, Kullmann C, Ivanova V, Förster S, Jagtap S, Meiser J, Leparc G, Schildknecht S, Adam M, Hiller K, Farhan H, Brunner T, Hartung T, Sachinidis A, Leist M.

Cell Death Dis. 2014 May 8;5:e1222. doi: 10.1038/cddis.2014.166.


Plasma Levels of Acylation-Stimulating Protein Are Strongly Predicted by Waist/Hip Ratio and Correlate with Decreased LDL Size in Men.

Saleh J, Wahab RA, Farhan H, Al-Amri I, Cianflone K.

ISRN Obes. 2013 Feb 12;2013:342802. doi: 10.1155/2013/342802. eCollection 2013.


A minimum-labeling approach for reconstructing protein networks across multiple conditions.

Mazza A, Gat-Viks I, Farhan H, Sharan R.

Algorithms Mol Biol. 2014 Feb 9;9(1):1. doi: 10.1186/1748-7188-9-1.


Incidence and pattern of thyroid dysfunction in patients on chronic amiodarone therapy: experience at a tertiary care centre in oman.

Farhan H, Albulushi A, Taqi A, Al-Hashim A, Al-Saidi K, Al-Rasadi K, Al-Mazroui A, Al-Zakwani I.

Open Cardiovasc Med J. 2013 Nov 29;7:122-6. doi: 10.2174/1874192401307010122. eCollection 2013.


Methods to study signaling at the Golgi apparatus.

Reitere V, Baschieri F, Millarte V, Farhan H.

Methods Cell Biol. 2013;118:345-58. doi: 10.1016/B978-0-12-417164-0.00021-5.


Chemical composition, in vitro cytotoxicity and anti-free radical properties of six extracts from Lebanese Trigonella berythea Boiss.

Farhan H, Rammal H, Hijazi A, Annan H, Daher A, Reda M, Badran B.

Pak J Pharm Sci. 2013 Nov;26(6):1157-63.


Plasma gamma-glutamyltransferase is strongly determined by acylation stimulating protein levels independent of insulin resistance in patients with acute coronary syndrome.

Saleh J, Farhan H, Al-Saqri I, Al-Riyami B, Cianflone K.

Dis Markers. 2013;35(3):155-61. doi: 10.1155/2013/914748. Epub 2013 Aug 21.


Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2.

Reiterer V, Fey D, Kolch W, Kholodenko BN, Farhan H.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2934-43. doi: 10.1073/pnas.1301985110. Epub 2013 Jul 11.


Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras.

Farhan H, Rammal H, Hijazi A, Daher A, Reda M, Annan H, Chokr A, Bassal A, Badran B.

Asian Pac J Trop Biomed. 2013 Jul;3(7):542-8. doi: 10.1016/S2221-1691(13)60110-0.


Regulation of traffic and organelle architecture of the ER-Golgi interface by signal transduction.

Tillmann KD, Millarte V, Farhan H.

Histochem Cell Biol. 2013 Sep;140(3):297-306. doi: 10.1007/s00418-013-1118-5. Epub 2013 Jul 3. Review.


Parallel exploitation of diverse host nutrients enhances Salmonella virulence.

Steeb B, Claudi B, Burton NA, Tienz P, Schmidt A, Farhan H, Mazé A, Bumann D.

PLoS Pathog. 2013;9(4):e1003301. doi: 10.1371/journal.ppat.1003301. Epub 2013 Apr 25.


Comparison of therapeutic lipid target achievements among high-risk patients in Oman.

Al-Waili K, Al-Zakwani I, Al-Dughaishi T, Baneerje Y, Al-Sabti H, Al-Hashmi K, Farhan H, Habsi KA, Al-Hinai AT, Al-Rasadi K.

Angiology. 2014 May;65(5):430-5. doi: 10.1177/0003319713482572. Epub 2013 Apr 5.


Crosstalk of small GTPases at the Golgi apparatus.

Baschieri F, Farhan H.

Small GTPases. 2012 Apr-Jun;3(2):80-90. doi: 10.4161/sgtp.19842. Review.


The Golgi in cell migration: regulation by signal transduction and its implications for cancer cell metastasis.

Millarte V, Farhan H.

ScientificWorldJournal. 2012;2012:498278. doi: 10.1100/2012/498278. Epub 2012 May 1. Review.


Safety of simvastatin and goal attainment for low-density lipoprotein cholesterol in sultan qaboos university hospital.

Al-Siyabi K, Farhan H, Al-Rasadi K, Al-Salhi A, Al-Hinai AT, Al-Zakwani I.

Oman Med J. 2010 Oct;25(4):264-8. doi: 10.5001/omj.2010.79.

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