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Items: 25

1.

The mitochondrial outer-membrane location of the EXD2 exonuclease contradicts its direct role in nuclear DNA repair.

Hensen F, Moretton A, van Esveld S, Farge G, Spelbrink JN.

Sci Rep. 2018 Mar 29;8(1):5368. doi: 10.1038/s41598-018-23690-y.

2.

Selective mitochondrial DNA degradation following double-strand breaks.

Moretton A, Morel F, Macao B, Lachaume P, Ishak L, Lefebvre M, Garreau-Balandier I, Vernet P, Falkenberg M, Farge G.

PLoS One. 2017 Apr 28;12(4):e0176795. doi: 10.1371/journal.pone.0176795. eCollection 2017.

3.

DNA maintenance following bleomycin-induced strand breaks does not require poly(ADP-ribosyl)ation activation in Drosophila S2 cells.

Ishak L, Moretton A, Garreau-Balandier I, Lefebvre M, Alziari S, Lachaume P, Morel F, Farge G, Vernet P, Dubessay P.

DNA Repair (Amst). 2016 Dec;48:8-16. doi: 10.1016/j.dnarep.2016.10.002. Epub 2016 Oct 21.

PMID:
27793508
4.

In vitro-reconstituted nucleoids can block mitochondrial DNA replication and transcription.

Farge G, Mehmedovic M, Baclayon M, van den Wildenberg SM, Roos WH, Gustafsson CM, Wuite GJ, Falkenberg M.

Cell Rep. 2014 Jul 10;8(1):66-74. doi: 10.1016/j.celrep.2014.05.046. Epub 2014 Jun 26.

5.

The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes.

Uhler JP, Spåhr H, Farge G, Clavel S, Larsson NG, Falkenberg M, Samuelsson T, Gustafsson CM.

Biochem Biophys Res Commun. 2014 Jan 3;443(1):7-12. doi: 10.1016/j.bbrc.2013.10.137. Epub 2013 Nov 6.

PMID:
24211586
6.

STED nanoscopy combined with optical tweezers reveals protein dynamics on densely covered DNA.

Heller I, Sitters G, Broekmans OD, Farge G, Menges C, Wende W, Hell SW, Peterman EJ, Wuite GJ.

Nat Methods. 2013 Sep;10(9):910-6. doi: 10.1038/nmeth.2599. Epub 2013 Aug 11.

PMID:
23934077
7.

A toolbox for generating single-stranded DNA in optical tweezers experiments.

Candelli A, Hoekstra TP, Farge G, Gross P, Peterman EJ, Wuite GJ.

Biopolymers. 2013 Sep;99(9):611-20. doi: 10.1002/bip.22225.

PMID:
23444293
8.

Protein sliding and DNA denaturation are essential for DNA organization by human mitochondrial transcription factor A.

Farge G, Laurens N, Broekmans OD, van den Wildenberg SM, Dekker LC, Gaspari M, Gustafsson CM, Peterman EJ, Falkenberg M, Wuite GJ.

Nat Commun. 2012;3:1013. doi: 10.1038/ncomms2001.

PMID:
22910359
9.

The mitochondrial DNA helicase TWINKLE can assemble on a closed circular template and support initiation of DNA synthesis.

Jemt E, Farge G, Bäckström S, Holmlund T, Gustafsson CM, Falkenberg M.

Nucleic Acids Res. 2011 Nov;39(21):9238-49. doi: 10.1093/nar/gkr653. Epub 2011 Aug 12.

10.

Sequence-specific stalling of DNA polymerase γ and the effects of mutations causing progressive ophthalmoplegia.

Atanassova N, Fusté JM, Wanrooij S, Macao B, Goffart S, Bäckström S, Farge G, Khvorostov I, Larsson NG, Spelbrink JN, Falkenberg M.

Hum Mol Genet. 2011 Mar 15;20(6):1212-23. doi: 10.1093/hmg/ddq565. Epub 2011 Jan 12.

PMID:
21228000
11.

Combining optical tweezers, single-molecule fluorescence microscopy, and microfluidics for studies of DNA-protein interactions.

Gross P, Farge G, Peterman EJ, Wuite GJ.

Methods Enzymol. 2010;475:427-53. doi: 10.1016/S0076-6879(10)75017-5.

PMID:
20627167
12.

Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging.

van Mameren J, Gross P, Farge G, Hooijman P, Modesti M, Falkenberg M, Wuite GJ, Peterman EJ.

Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18231-6. doi: 10.1073/pnas.0904322106. Epub 2009 Oct 19.

13.

Structure-function defects of the twinkle amino-terminal region in progressive external ophthalmoplegia.

Holmlund T, Farge G, Pande V, Korhonen J, Nilsson L, Falkenberg M.

Biochim Biophys Acta. 2009 Feb;1792(2):132-9. doi: 10.1016/j.bbadis.2008.11.009. Epub 2008 Nov 24.

14.

Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro.

Wanrooij S, Fusté JM, Farge G, Shi Y, Gustafsson CM, Falkenberg M.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11122-7. doi: 10.1073/pnas.0805399105. Epub 2008 Aug 6.

15.

Structure-function defects of the TWINKLE linker region in progressive external ophthalmoplegia.

Korhonen JA, Pande V, Holmlund T, Farge G, Pham XH, Nilsson L, Falkenberg M.

J Mol Biol. 2008 Mar 28;377(3):691-705. doi: 10.1016/j.jmb.2008.01.035. Epub 2008 Jan 26.

PMID:
18279890
16.

The N-terminal domain of TWINKLE contributes to single-stranded DNA binding and DNA helicase activities.

Farge G, Holmlund T, Khvorostova J, Rofougaran R, Hofer A, Falkenberg M.

Nucleic Acids Res. 2008 Feb;36(2):393-403. Epub 2007 Nov 26.

17.

The accessory subunit B of DNA polymerase gamma is required for mitochondrial replisome function.

Farge G, Pham XH, Holmlund T, Khorostov I, Falkenberg M.

Nucleic Acids Res. 2007;35(3):902-11. Epub 2007 Jan 23.

18.

Conserved sequence box II directs transcription termination and primer formation in mitochondria.

Pham XH, Farge G, Shi Y, Gaspari M, Gustafsson CM, Falkenberg M.

J Biol Chem. 2006 Aug 25;281(34):24647-52. Epub 2006 Jun 21.

19.

The human mitochondrial transcription termination factor (mTERF) is fully active in vitro in the non-phosphorylated form.

Asin-Cayuela J, Schwend T, Farge G, Gustafsson CM.

J Biol Chem. 2005 Jul 8;280(27):25499-505. Epub 2005 May 17.

20.

Coordinated decrease of the expression of the mitochondrial and nuclear complex I genes in a mitochondrial mutant of Drosophila.

Farge G, Touraille S, Lachaume P, Debise R, Procaccio V, Alziari S.

J Bioenerg Biomembr. 2004 Apr;36(2):203-10.

PMID:
15224970
21.

Scope of practice--twenty-first century.

Farge GL.

Virtual Mentor. 2004 Jun 1;6(6). pii: virtualmentor.2004.6.6.pfor1-0406. doi: 10.1001/virtualmentor.2004.6.6.pfor1-0406. No abstract available.

PMID:
23260640
22.

The respiratory chain complex thresholds in mitochondria of a Drosophila subobscura mutant strain.

Farge G, Touraille S, Debise R, Alziari S.

Biochimie. 2002 Dec;84(12):1189-97.

PMID:
12628295
23.

The nuclear genome is involved in heteroplasmy control in a mitochondrial mutant strain of Drosophila subobscura.

Farge G, Touraille S, Le Goff S, Petit N, Renoux M, Morel F, Alziari S.

Eur J Biochem. 2002 Feb;269(3):998-1005.

24.

Please, doctor. Turn off my pacemaker.

La Farge G.

Med Econ. 1997 May 12;74(10):177-80. No abstract available.

PMID:
10167106
25.

SUPPLEMENT REPORT OF THE TASK FORCE ON BIOMATERIALS TO THE CARDIOLOGY ADVISORY COMMITTEE OF THE NHLBI.

Galletti PM, Brash JL, Keller KH, La Farge G, Mason RG, Pierce WS, Reynolds JA.

Cardiovasc Dis. 1978 Sep;5(3):293-314. No abstract available.

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