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Items: 1 to 50 of 122

1.

Computational Evaluation of B-Cell Clone Sizes in Bulk Populations.

Rosenfeld AM, Meng W, Chen DY, Zhang B, Granot T, Farber DL, Hershberg U, Luning Prak ET.

Front Immunol. 2018 Jun 29;9:1472. doi: 10.3389/fimmu.2018.01472. eCollection 2018.

2.

Developmental Regulation of Effector and Resident Memory T Cell Generation during Pediatric Viral Respiratory Tract Infection.

Connors TJ, Baird JS, Yopes MC, Zens KD, Pethe K, Ravindranath TM, Ho SH, Farber DL.

J Immunol. 2018 Jul 15;201(2):432-439. doi: 10.4049/jimmunol.1800396. Epub 2018 May 30.

PMID:
29848753
3.

Human T Cell Development, Localization, and Function throughout Life.

Kumar BV, Connors TJ, Farber DL.

Immunity. 2018 Feb 20;48(2):202-213. doi: 10.1016/j.immuni.2018.01.007. Review.

PMID:
29466753
4.

Biased Generation and In Situ Activation of Lung Tissue-Resident Memory CD4 T Cells in the Pathogenesis of Allergic Asthma.

Turner DL, Goldklang M, Cvetkovski F, Paik D, Trischler J, Barahona J, Cao M, Dave R, Tanna N, D'Armiento JM, Farber DL.

J Immunol. 2018 Mar 1;200(5):1561-1569. doi: 10.4049/jimmunol.1700257. Epub 2018 Jan 17.

PMID:
29343554
5.

The neonatal window of opportunity-early priming for life.

Renz H, Adkins BD, Bartfeld S, Blumberg RS, Farber DL, Garssen J, Ghazal P, Hackam DJ, Marsland BJ, McCoy KD, Penders J, Prinz I, Verhasselt V, von Mutius E, Weiser JN, Wesemann DR, Hornef MW.

J Allergy Clin Immunol. 2018 Apr;141(4):1212-1214. doi: 10.1016/j.jaci.2017.11.019. Epub 2017 Dec 14. No abstract available.

PMID:
29247715
6.

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites.

Kumar BV, Ma W, Miron M, Granot T, Guyer RS, Carpenter DJ, Senda T, Sun X, Ho SH, Lerner H, Friedman AL, Shen Y, Farber DL.

Cell Rep. 2017 Sep 19;20(12):2921-2934. doi: 10.1016/j.celrep.2017.08.078.

7.

Tissue compartmentalization of T cell responses during early life.

Zens KD, Connors T, Farber DL.

Semin Immunopathol. 2017 Nov;39(6):593-604. doi: 10.1007/s00281-017-0648-7. Epub 2017 Sep 11. Review.

PMID:
28894935
8.

The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation.

Klose CSN, Mahlakõiv T, Moeller JB, Rankin LC, Flamar AL, Kabata H, Monticelli LA, Moriyama S, Putzel GG, Rakhilin N, Shen X, Kostenis E, König GM, Senda T, Carpenter D, Farber DL, Artis D.

Nature. 2017 Sep 14;549(7671):282-286. doi: 10.1038/nature23676. Epub 2017 Sep 6.

PMID:
28869965
9.

Reduced generation of lung tissue-resident memory T cells during infancy.

Zens KD, Chen JK, Guyer RS, Wu FL, Cvetkovski F, Miron M, Farber DL.

J Exp Med. 2017 Oct 2;214(10):2915-2932. doi: 10.1084/jem.20170521. Epub 2017 Aug 30.

10.

An atlas of B-cell clonal distribution in the human body.

Meng W, Zhang B, Schwartz GW, Rosenfeld AM, Ren D, Thome JJC, Carpenter DJ, Matsuoka N, Lerner H, Friedman AL, Granot T, Farber DL, Shlomchik MJ, Hershberg U, Luning Prak ET.

Nat Biotechnol. 2017 Sep;35(9):879-884. doi: 10.1038/nbt.3942. Epub 2017 Aug 21.

11.

Human immunology studies using organ donors: Impact of clinical variations on immune parameters in tissues and circulation.

Carpenter DJ, Granot T, Matsuoka N, Senda T, Kumar BV, Thome JJC, Gordon CL, Miron M, Weiner J, Connors T, Lerner H, Friedman A, Kato T, Griesemer AD, Farber DL.

Am J Transplant. 2018 Jan;18(1):74-88. doi: 10.1111/ajt.14434. Epub 2017 Sep 8.

PMID:
28719147
12.

Thymic-Peripheral Crosstalk in Lymphodepletion Therapy.

Snyder ME, Farber DL.

Am J Transplant. 2017 Aug;17(8):1970-1971. doi: 10.1111/ajt.14370. Epub 2017 Jun 19. No abstract available.

PMID:
28544604
13.

GABAA receptor α4-subunit knockout enhances lung inflammation and airway reactivity in a murine asthma model.

Yocum GT, Turner DL, Danielsson J, Barajas MB, Zhang Y, Xu D, Harrison NL, Homanics GE, Farber DL, Emala CW.

Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L406-L415. doi: 10.1152/ajplung.00107.2017. Epub 2017 May 4.

PMID:
28473323
14.

Longterm maintenance of human naive T cells through in situ homeostasis in lymphoid tissue sites.

Thome JJ, Grinshpun B, Kumar BV, Kubota M, Ohmura Y, Lerner H, Sempowski GD, Shen Y, Farber DL.

Sci Immunol. 2016 Dec;1(6). pii: eaah6506. doi: 10.1126/sciimmunol.aah6506. Epub 2016 Dec 2.

15.

Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life.

Granot T, Senda T, Carpenter DJ, Matsuoka N, Weiner J, Gordon CL, Miron M, Kumar BV, Griesemer A, Ho SH, Lerner H, Thome JJC, Connors T, Reizis B, Farber DL.

Immunity. 2017 Mar 21;46(3):504-515. doi: 10.1016/j.immuni.2017.02.019.

16.

Bidirectional intragraft alloreactivity drives the repopulation of human intestinal allografts and correlates with clinical outcome.

Zuber J, Shonts B, Lau SP, Obradovic A, Fu J, Yang S, Lambert M, Coley S, Weiner J, Thome J, DeWolf S, Farber DL, Shen Y, Caillat-Zucman S, Bhagat G, Griesemer A, Martinez M, Kato T, Sykes M.

Sci Immunol. 2016 Oct;1(4). pii: eaah3732. doi: 10.1126/sciimmunol.aah3732. Epub 2016 Oct 7.

17.

Tissue reservoirs of antiviral T cell immunity in persistent human CMV infection.

Gordon CL, Miron M, Thome JJ, Matsuoka N, Weiner J, Rak MA, Igarashi S, Granot T, Lerner H, Goodrum F, Farber DL.

J Exp Med. 2017 Mar 6;214(3):651-667. doi: 10.1084/jem.20160758. Epub 2017 Jan 27.

18.

Long-term Persistence of Innate Lymphoid Cells in the Gut After Intestinal Transplantation.

Weiner J, Zuber J, Shonts B, Yang S, Fu J, Martinez M, Farber DL, Kato T, Sykes M.

Transplantation. 2017 Oct;101(10):2449-2454. doi: 10.1097/TP.0000000000001593.

PMID:
27941430
19.

CD4+ T cell effector commitment coupled to self-renewal by asymmetric cell divisions.

Nish SA, Zens KD, Kratchmarov R, Lin WW, Adams WC, Chen YH, Yen B, Rothman NJ, Bhandoola A, Xue HH, Farber DL, Reiner SL.

J Exp Med. 2017 Jan;214(1):39-47. doi: 10.1084/jem.20161046. Epub 2016 Dec 6.

20.

Phonon triggered rhombohedral lattice distortion in vanadium at high pressure.

Antonangeli D, Farber DL, Bosak A, Aracne CM, Ruddle DG, Krisch M.

Sci Rep. 2016 Aug 19;6:31887. doi: 10.1038/srep31887.

21.
22.

The Latent Reservoir for HIV-1: How Immunologic Memory and Clonal Expansion Contribute to HIV-1 Persistence.

Murray AJ, Kwon KJ, Farber DL, Siliciano RF.

J Immunol. 2016 Jul 15;197(2):407-17. doi: 10.4049/jimmunol.1600343. Review.

23.

Viral Bronchiolitis in Children.

Connors T, Baird J, Farber DL.

N Engl J Med. 2016 May 5;374(18):1791-2. doi: 10.1056/NEJMc1601509. No abstract available.

PMID:
27144866
24.

Immunological memory: lessons from the past and a look to the future.

Farber DL, Netea MG, Radbruch A, Rajewsky K, Zinkernagel RM.

Nat Rev Immunol. 2016 Feb;16(2):124-8. doi: 10.1038/nri.2016.13. Review.

PMID:
26831526
25.

Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues.

Thome JJ, Bickham KL, Ohmura Y, Kubota M, Matsuoka N, Gordon C, Granot T, Griesemer A, Lerner H, Kato T, Farber DL.

Nat Med. 2016 Jan;22(1):72-7. doi: 10.1038/nm.4008. Epub 2015 Dec 14.

26.

Airway CD8(+) T Cells Are Associated with Lung Injury during Infant Viral Respiratory Tract Infection.

Connors TJ, Ravindranath TM, Bickham KL, Gordon CL, Zhang F, Levin B, Baird JS, Farber DL.

Am J Respir Cell Mol Biol. 2016 Jun;54(6):822-30. doi: 10.1165/rcmb.2015-0297OC.

27.

Immune Modulation of the T Cell Response in Asthma through Wnt10b.

Trischler J, Shiomi T, Turner DL, Sklepkiewicz PL, Goldklang MP, Tanaka KF, Xu M, Farber DL, D'Armiento JM.

Am J Respir Cell Mol Biol. 2016 Apr;54(4):584-93. doi: 10.1165/rcmb.2014-0425OC.

28.

Conditional PDK1 Ablation Promotes Epidermal and T-Cell-Mediated Dysfunctions Leading to Inflammatory Skin Disease.

Yu M, Owens DM, Ghosh S, Farber DL.

J Invest Dermatol. 2015 Nov;135(11):2688-2696. doi: 10.1038/jid.2015.232. Epub 2015 Jun 22.

29.

Emerging concepts in tissue-resident T cells: lessons from humans.

Thome JJ, Farber DL.

Trends Immunol. 2015 Jul;36(7):428-35. doi: 10.1016/j.it.2015.05.003. Epub 2015 Jun 10. Review.

30.

The prostaglandin D₂ receptor CRTH2 regulates accumulation of group 2 innate lymphoid cells in the inflamed lung.

Wojno ED, Monticelli LA, Tran SV, Alenghat T, Osborne LC, Thome JJ, Willis C, Budelsky A, Farber DL, Artis D.

Mucosal Immunol. 2015 Nov;8(6):1313-23. doi: 10.1038/mi.2015.21. Epub 2015 Apr 8.

31.

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.

Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P, Artis D.

Nature. 2015 Mar 12;519(7542):242-6. doi: 10.1038/nature14115. Epub 2014 Dec 22.

32.

Spatial map of human T cell compartmentalization and maintenance over decades of life.

Thome JJ, Yudanin N, Ohmura Y, Kubota M, Grinshpun B, Sathaliyawala T, Kato T, Lerner H, Shen Y, Farber DL.

Cell. 2014 Nov 6;159(4):814-28. doi: 10.1016/j.cell.2014.10.026.

33.

CD45 ligation expands Tregs by promoting interactions with DCs.

Camirand G, Wang Y, Lu Y, Wan YY, Lin Y, Deng S, Guz G, Perkins DL, Finn PW, Farber DL, Flavell RA, Shlomchik WD, Lakkis FG, Rudd CE, Rothstein DM.

J Clin Invest. 2014 Oct;124(10):4603-13. doi: 10.1172/JCI74087. Epub 2014 Sep 9.

34.

Mucosal resident memory CD4 T cells in protection and immunopathology.

Turner DL, Farber DL.

Front Immunol. 2014 Jul 14;5:331. doi: 10.3389/fimmu.2014.00331. eCollection 2014. Review.

35.

Memory CD4 T cells in influenza.

Zens KD, Farber DL.

Curr Top Microbiol Immunol. 2015;386:399-421. doi: 10.1007/82_2014_401. Review.

36.

Tissue-resident T cells, in situ immunity and transplantation.

Turner DL, Gordon CL, Farber DL.

Immunol Rev. 2014 Mar;258(1):150-66. doi: 10.1111/imr.12149. Review.

PMID:
24517432
37.

An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo.

Subramanian M, Hayes CD, Thome JJ, Thorp E, Matsushima GK, Herz J, Farber DL, Liu K, Lakshmana M, Tabas I.

J Clin Invest. 2014 Mar;124(3):1296-308. doi: 10.1172/JCI72051. Epub 2014 Feb 10.

38.

Human memory T cells: generation, compartmentalization and homeostasis.

Farber DL, Yudanin NA, Restifo NP.

Nat Rev Immunol. 2014 Jan;14(1):24-35. doi: 10.1038/nri3567. Epub 2013 Dec 13. Review.

39.

Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.

Siracusa MC, Saenz SA, Wojno ED, Kim BS, Osborne LC, Ziegler CG, Benitez AJ, Ruymann KR, Farber DL, Sleiman PM, Hakonarson H, Cianferoni A, Wang ML, Spergel JM, Comeau MR, Artis D.

Immunity. 2013 Dec 12;39(6):1158-70. doi: 10.1016/j.immuni.2013.09.016.

40.

Lung niches for the generation and maintenance of tissue-resident memory T cells.

Turner DL, Bickham KL, Thome JJ, Kim CY, D'Ovidio F, Wherry EJ, Farber DL.

Mucosal Immunol. 2014 May;7(3):501-10. doi: 10.1038/mi.2013.67. Epub 2013 Sep 25.

41.

Splenic priming of virus-specific CD8 T cells following influenza virus infection.

Turner DL, Bickham KL, Farber DL, Lefrançois L.

J Virol. 2013 Apr;87(8):4496-506. doi: 10.1128/JVI.03413-12. Epub 2013 Feb 6.

42.

Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets.

Sathaliyawala T, Kubota M, Yudanin N, Turner D, Camp P, Thome JJ, Bickham KL, Lerner H, Goldstein M, Sykes M, Kato T, Farber DL.

Immunity. 2013 Jan 24;38(1):187-97. doi: 10.1016/j.immuni.2012.09.020. Epub 2012 Dec 20.

43.

Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

Sonnenberg GF, Monticelli LA, Alenghat T, Fung TC, Hutnick NA, Kunisawa J, Shibata N, Grunberg S, Sinha R, Zahm AM, Tardif MR, Sathaliyawala T, Kubota M, Farber DL, Collman RG, Shaked A, Fouser LA, Weiner DB, Tessier PA, Friedman JR, Kiyono H, Bushman FD, Chang KM, Artis D.

Science. 2012 Jun 8;336(6086):1321-5. doi: 10.1126/science.1222551. Epub 2012 Jun 6.

44.

Endogenous expansion of regulatory T cells leads to long-term islet graft survival in diabetic NOD mice.

Shi Q, Lees JR, Scott DW, Farber DL, Bartlett ST.

Am J Transplant. 2012 May;12(5):1124-32. doi: 10.1111/j.1600-6143.2011.03943.x. Epub 2012 Feb 2.

45.

Cutting edge: Tissue-retentive lung memory CD4 T cells mediate optimal protection to respiratory virus infection.

Teijaro JR, Turner D, Pham Q, Wherry EJ, Lefrançois L, Farber DL.

J Immunol. 2011 Dec 1;187(11):5510-4. doi: 10.4049/jimmunol.1102243. Epub 2011 Nov 4.

46.

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus.

Monticelli LA, Sonnenberg GF, Abt MC, Alenghat T, Ziegler CG, Doering TA, Angelosanto JM, Laidlaw BJ, Yang CY, Sathaliyawala T, Kubota M, Turner D, Diamond JM, Goldrath AW, Farber DL, Collman RG, Wherry EJ, Artis D.

Nat Immunol. 2011 Nov;12(11):1045-54. doi: 10.1031/ni.2131.

47.

A repertoire-independent and cell-intrinsic defect in murine GVHD induction by effector memory T cells.

Juchem KW, Anderson BE, Zhang C, McNiff JM, Demetris AJ, Farber DL, Caton AJ, Shlomchik WD, Shlomchik MJ.

Blood. 2011 Dec 1;118(23):6209-19. doi: 10.1182/blood-2011-01-330035. Epub 2011 Jul 18.

48.

NF-κB signaling participates in both RANKL- and IL-4-induced macrophage fusion: receptor cross-talk leads to alterations in NF-κB pathways.

Yu M, Qi X, Moreno JL, Farber DL, Keegan AD.

J Immunol. 2011 Aug 15;187(4):1797-806. doi: 10.4049/jimmunol.1002628. Epub 2011 Jul 6.

49.

Enhancing alloreactivity does not restore GVHD induction but augments skin graft rejection by CD4⁺ effector memory T cells.

Anderson BE, Tang AL, Wang Y, Froicu M, Rothstein D, McNiff JM, Jain D, Demetris AJ, Farber DL, Shlomchik WD, Shlomchik MJ.

Eur J Immunol. 2011 Sep;41(9):2782-92. doi: 10.1002/eji.201141678. Epub 2011 Aug 18.

50.

Transcriptional control of rapid recall by memory CD4 T cells.

Lai W, Yu M, Huang MN, Okoye F, Keegan AD, Farber DL.

J Immunol. 2011 Jul 1;187(1):133-40. doi: 10.4049/jimmunol.1002742. Epub 2011 Jun 3.

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