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Items: 1 to 50 of 67

1.

RORγt-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells.

Rizzo A, Di Giovangiulio M, Stolfi C, Franzè E, Fehling HJ, Carsetti R, Giorda E, Colantoni A, Ortenzi A, Rugge M, Mescoli C, Monteleone G, Fantini MC.

Cancer Immunol Res. 2018 Jul 10. pii: canimm.0698.2017. doi: 10.1158/2326-6066.CIR-17-0698. [Epub ahead of print]

PMID:
29991500
2.

Fast, low-cost preparation of hackmanite minerals with reversible photochromic behavior using a microwave-assisted structure-conversion method.

Carvalho JM, Norrbo I, Ando RA, Brito HF, Fantini MCA, Lastusaari M.

Chem Commun (Camb). 2018 Jun 28;54(53):7326-7329. doi: 10.1039/c8cc03033b.

PMID:
29911228
3.

Liquid Crystalline Systems Based on Glyceryl Monooleate and Penetration Enhancers for Skin Delivery of Celecoxib: Characterization, In Vitro Drug Release, and In Vivo Studies.

Dante MCL, Borgheti-Cardoso LN, Fantini MCA, Praça FSG, Medina WSG, Pierre MBR, Lara MG.

J Pharm Sci. 2018 Mar;107(3):870-878. doi: 10.1016/j.xphs.2017.10.039. Epub 2017 Nov 4.

PMID:
29108729
4.

Update on the Therapeutic Efficacy of Tregs in IBD: Thumbs up or Thumbs down?

Fantini MC, Monteleone G.

Inflamm Bowel Dis. 2017 Oct;23(10):1682-1688. doi: 10.1097/MIB.0000000000001272. Review.

PMID:
28906289
5.

CCL20 Is Negatively Regulated by TGF-β1 in Intestinal Epithelial Cells and Reduced in Crohn's Disease Patients With a Successful Response to Mongersen, a Smad7 Antisense Oligonucleotide.

Marafini I, Monteleone I, Dinallo V, Di Fusco D, De Simone V, Laudisi F, Fantini MC, Di Sabatino A, Pallone F, Monteleone G.

J Crohns Colitis. 2017 May 1;11(5):603-609. doi: 10.1093/ecco-jcc/jjw191.

PMID:
28453765
6.

Smad7 knockdown activates protein kinase RNA-associated eIF2α pathway leading to colon cancer cell death.

De Simone V, Bevivino G, Sedda S, Izzo R, Laudisi F, Dinallo V, Franzè E, Colantoni A, Ortenzi A, Salvatori S, Rossi P, Sica GS, Fantini MC, Stolfi C, Monteleone G.

Cell Death Dis. 2017 Mar 16;8(3):e2681. doi: 10.1038/cddis.2017.103.

7.

In Situ Gelling Liquid Crystalline System as Local siRNA Delivery System.

Borgheti-Cardoso LN, Kooijmans SAA, Fens MHAM, van der Meel R, Vicentini FTMC, Fantini MCA, Bentley MVLB, Schiffelers RM.

Mol Pharm. 2017 May 1;14(5):1681-1690. doi: 10.1021/acs.molpharmaceut.6b01141. Epub 2017 Mar 28.

PMID:
28291360
8.

Nanostructured SBA-15 silica: An effective protective vehicle to oral hepatitis B vaccine immunization.

Scaramuzzi K, Tanaka GD, Neto FM, Garcia PR, Gabrili JJ, Oliveira DC, Tambourgi DV, Mussalem JS, Paixão-Cavalcante D, D'Azeredo Orlando MT, Botosso VF, Oliveira CL, Fantini MC, Sant'Anna OA.

Nanomedicine. 2016 Nov;12(8):2241-2250. doi: 10.1016/j.nano.2016.06.003. Epub 2016 Jun 23.

PMID:
27339784
9.

Optimization of protoporphyrin IX skin delivery for topical photodynamic therapy: Nanodispersions of liquid-crystalline phase as nanocarriers.

Rossetti FC, Depieri LV, Praça FG, Del Ciampo JO, Fantini MC, Pierre MB, Tedesco AC, Bentley MV.

Eur J Pharm Sci. 2016 Feb 15;83:99-108. doi: 10.1016/j.ejps.2015.12.003. Epub 2015 Dec 3.

PMID:
26657201
10.

An in situ gelling liquid crystalline system based on monoglycerides and polyethylenimine for local delivery of siRNAs.

Borgheti-Cardoso LN, Depieri LV, Kooijmans SA, Diniz H, Calzzani RA, Vicentini FT, van der Meel R, Fantini MC, Iyomasa MM, Schiffelers RM, Bentley MV.

Eur J Pharm Sci. 2015 Jul 10;74:103-17. doi: 10.1016/j.ejps.2015.04.017. Epub 2015 Apr 25.

PMID:
25917525
11.

Interleukin-21 sustains inflammatory signals that contribute to sporadic colon tumorigenesis.

De Simone V, Ronchetti G, Franzè E, Colantoni A, Ortenzi A, Fantini MC, Rizzo A, Sica GS, Sileri P, Rossi P, MacDonald TT, Pallone F, Monteleone G, Stolfi C.

Oncotarget. 2015 Apr 30;6(12):9908-23.

12.

Activation of TGF-β-induced non-Smad signaling pathways during Th17 differentiation.

Hasan M, Neumann B, Haupeltshofer S, Stahlke S, Fantini MC, Angstwurm K, Bogdahn U, Kleiter I.

Immunol Cell Biol. 2015 Aug;93(7):662-72. doi: 10.1038/icb.2015.21. Epub 2015 Mar 31.

PMID:
25823994
13.

Mongersen, an oral SMAD7 antisense oligonucleotide, and Crohn's disease.

Monteleone G, Neurath MF, Ardizzone S, Di Sabatino A, Fantini MC, Castiglione F, Scribano ML, Armuzzi A, Caprioli F, Sturniolo GC, Rogai F, Vecchi M, Atreya R, Bossa F, Onali S, Fichera M, Corazza GR, Biancone L, Savarino V, Pica R, Orlando A, Pallone F.

N Engl J Med. 2015 Mar 19;372(12):1104-13. doi: 10.1056/NEJMoa1407250.

14.

Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.

De Simone V, Franzè E, Ronchetti G, Colantoni A, Fantini MC, Di Fusco D, Sica GS, Sileri P, MacDonald TT, Pallone F, Monteleone G, Stolfi C.

Oncogene. 2015 Jul;34(27):3493-503. doi: 10.1038/onc.2014.286. Epub 2014 Sep 1.

15.

A functional role for Smad7 in sustaining colon cancer cell growth and survival.

Stolfi C, De Simone V, Colantoni A, Franzè E, Ribichini E, Fantini MC, Caruso R, Monteleone I, Sica GS, Sileri P, MacDonald TT, Pallone F, Monteleone G.

Cell Death Dis. 2014 Feb 20;5:e1073. doi: 10.1038/cddis.2014.49.

16.

The impact of translational research on gastroenterology.

Di Sabatino A, Moschetta A, Conte D, Tiribelli C; Translational Committee of the Italian Society of Gastroenterology, Caprioli FA, Fabris L, Fantini MC, Frulloni L, Monteleone G, Romano M, Sarnelli G, Baroni GS.

Dig Liver Dis. 2014 Apr;46(4):293-4. doi: 10.1016/j.dld.2013.12.015. Epub 2014 Feb 5. No abstract available.

PMID:
24508099
17.

Smad7 induces plasticity in tumor-infiltrating Th17 cells and enables TNF-alpha-mediated killing of colorectal cancer cells.

Rizzo A, De Mare V, Rocchi C, Stolfi C, Colantoni A, Neurath MF, Macdonald TT, Pallone F, Monteleone G, Fantini MC.

Carcinogenesis. 2014 Jul;35(7):1536-46. doi: 10.1093/carcin/bgu027. Epub 2014 Jan 30.

PMID:
24480808
18.

Liquid crystalline phase nanodispersions enable skin delivery of siRNA.

Vicentini FT, Depieri LV, Polizello AC, Del Ciampo JO, Spadaro AC, Fantini MC, Vitória Lopes Badra Bentley M.

Eur J Pharm Biopharm. 2013 Jan;83(1):16-24. doi: 10.1016/j.ejpb.2012.08.011. Epub 2012 Sep 23.

PMID:
23010565
19.

Phase I clinical trial of Smad7 knockdown using antisense oligonucleotide in patients with active Crohn's disease.

Monteleone G, Fantini MC, Onali S, Zorzi F, Sancesario G, Bernardini S, Calabrese E, Viti F, Monteleone I, Biancone L, Pallone F.

Mol Ther. 2012 Apr;20(4):870-6. doi: 10.1038/mt.2011.290. Epub 2012 Jan 17.

20.

Nanostructured SBA-15 silica as an adjuvant in immunizations with hepatitis B vaccine.

Scaramuzzi K, Oliveira DC, Carvalho LV, Tambourgi DV, Tenório EC, Rizzi M, Mussalem J, Fantini MC, Botosso VF, Sant Anna OA.

Einstein (Sao Paulo). 2011 Dec;9(4):436-41. doi: 10.1590/S1679-45082011AO2162. English, Portuguese.

21.

Smad7 expression in T cells prevents colitis-associated cancer.

Rizzo A, Waldner MJ, Stolfi C, Sarra M, Fina D, Becker C, Neurath MF, Macdonald TT, Pallone F, Monteleone G, Fantini MC.

Cancer Res. 2011 Dec 15;71(24):7423-32. doi: 10.1158/0008-5472.CAN-11-1895. Epub 2011 Oct 25.

22.

Involvement of interleukin-21 in the regulation of colitis-associated colon cancer.

Stolfi C, Rizzo A, Franzè E, Rotondi A, Fantini MC, Sarra M, Caruso R, Monteleone I, Sileri P, Franceschilli L, Caprioli F, Ferrero S, MacDonald TT, Pallone F, Monteleone G.

J Exp Med. 2011 Oct 24;208(11):2279-90. doi: 10.1084/jem.20111106. Epub 2011 Oct 10.

23.

Intestinal inflammation and colorectal cancer: a double-edged sword?

Rizzo A, Pallone F, Monteleone G, Fantini MC.

World J Gastroenterol. 2011 Jul 14;17(26):3092-100. doi: 10.3748/wjg.v17.i26.3092. Review.

24.

2-methoxy-5-amino-N-hydroxybenzamide sensitizes colon cancer cells to TRAIL-induced apoptosis by regulating death receptor 5 and survivin expression.

Stolfi C, Caruso R, Franzè E, Rizzo A, Rotondi A, Monteleone I, Fantini MC, Pallone F, Monteleone G.

Mol Cancer Ther. 2011 Oct;10(10):1969-81. doi: 10.1158/1535-7163.MCT-11-0316. Epub 2011 Aug 4.

25.

Inhibition of colitis by IL-25 associates with induction of alternatively activated macrophages.

Rizzo A, Monteleone I, Fina D, Stolfi C, Caruso R, Fantini MC, Franzè E, Schwendener R, Pallone F, Monteleone G.

Inflamm Bowel Dis. 2012 Mar;18(3):449-59. doi: 10.1002/ibd.21799. Epub 2011 Jun 17.

PMID:
21688353
26.

Regulation of homeostasis and inflammation in the intestine.

MacDonald TT, Monteleone I, Fantini MC, Monteleone G.

Gastroenterology. 2011 May;140(6):1768-75. doi: 10.1053/j.gastro.2011.02.047. Review.

PMID:
21530743
27.

Analysis of liquid crystalline nanoparticles by small angle X-ray diffraction: evaluation of drug and pharmaceutical additives influence on the internal structure.

Rossetti FC, Fantini MC, Carollo AR, Tedesco AC, Bentley MV.

J Pharm Sci. 2011 Jul;100(7):2849-57. doi: 10.1002/jps.22522. Epub 2011 Feb 18.

PMID:
21337546
28.

Immunological parameters related to the adjuvant effect of the ordered mesoporous silica SBA-15.

Carvalho LV, Ruiz Rde C, Scaramuzzi K, Marengo EB, Matos JR, Tambourgi DV, Fantini MC, Sant'Anna OA.

Vaccine. 2010 Nov 23;28(50):7829-36. doi: 10.1016/j.vaccine.2010.09.087. Epub 2010 Oct 25.

PMID:
20937318
29.

Crystallite size-dependent phases in nanocrystalline ZrO(2)-Sc(2)O(3).

Abdala PM, Fantini MC, Craievich AF, Lamas DG.

Phys Chem Chem Phys. 2010 Mar 28;12(12):2822-9. doi: 10.1039/b922541b. Epub 2010 Jan 27.

PMID:
20449372
30.

Interferon-gamma-expressing cells are a major source of interleukin-21 in inflammatory bowel diseases.

Sarra M, Monteleone I, Stolfi C, Fantini MC, Sileri P, Sica G, Tersigni R, Macdonald TT, Pallone F, Monteleone G.

Inflamm Bowel Dis. 2010 Aug;16(8):1332-9. doi: 10.1002/ibd.21238.

PMID:
20186935
31.

Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine.

Stolfi C, Sarra M, Caruso R, Fantini MC, Fina D, Pellegrini R, Palmieri G, Macdonald TT, Pallone F, Monteleone G.

Gastroenterology. 2010 Jan;138(1):221-30. doi: 10.1053/j.gastro.2009.08.062. Epub 2009 Sep 6.

PMID:
19737563
32.

Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut.

Caruso R, Sarra M, Stolfi C, Rizzo A, Fina D, Fantini MC, Pallone F, MacDonald TT, Monteleone G.

Gastroenterology. 2009 Jun;136(7):2270-9. doi: 10.1053/j.gastro.2009.02.049.

PMID:
19505427
33.

Common immunologic mechanisms in inflammatory bowel disease and spondylarthropathies.

Fantini MC, Pallone F, Monteleone G.

World J Gastroenterol. 2009 May 28;15(20):2472-8.

34.

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

Fantini MC, Rizzo A, Fina D, Caruso R, Sarra M, Stolfi C, Becker C, Macdonald TT, Pallone F, Neurath MF, Monteleone G.

Gastroenterology. 2009 Apr;136(4):1308-16, e1-3. doi: 10.1053/j.gastro.2008.12.053. Epub 2008 Dec 27.

PMID:
19192480
35.

Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.

Caruso R, Stolfi C, Sarra M, Rizzo A, Fantini MC, Pallone F, MacDonald TT, Monteleone G.

Blood. 2009 Apr 9;113(15):3512-9. doi: 10.1182/blood-2008-08-172767. Epub 2009 Jan 7.

36.

IL-21 comes of age as a regulator of effector T cells in the gut.

Fantini MC, Monteleone G, MacDonald TT.

Mucosal Immunol. 2008 Mar;1(2):110-5. doi: 10.1038/mi.2007.17. Epub 2008 Jan 23. Review.

PMID:
19079168
37.

Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phase.

Stolfi C, Fina D, Caruso R, Caprioli F, Fantini MC, Rizzo A, Sarra M, Pallone F, Monteleone G.

Carcinogenesis. 2008 Jun;29(6):1258-66. doi: 10.1093/carcin/bgn122. Epub 2008 May 20.

PMID:
18495657
38.

Cytokines: from gut inflammation to colorectal cancer.

Fantini MC, Pallone F.

Curr Drug Targets. 2008 May;9(5):375-80. Review.

PMID:
18473765
39.

Regulation of gut inflammation and th17 cell response by interleukin-21.

Fina D, Sarra M, Fantini MC, Rizzo A, Caruso R, Caprioli F, Stolfi C, Cardolini I, Dottori M, Boirivant M, Pallone F, Macdonald TT, Monteleone G.

Gastroenterology. 2008 Apr;134(4):1038-48. doi: 10.1053/j.gastro.2008.01.041. Epub 2008 Jan 17.

PMID:
18395085
40.

IL-23-mediated regulation of IL-17 production in Helicobacter pylori-infected gastric mucosa.

Caruso R, Fina D, Paoluzi OA, Del Vecchio Blanco G, Stolfi C, Rizzo A, Caprioli F, Sarra M, Andrei F, Fantini MC, MacDonald TT, Pallone F, Monteleone G.

Eur J Immunol. 2008 Feb;38(2):470-8. doi: 10.1002/eji.200737635.

41.

Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid.

Stolfi C, Fina D, Caruso R, Caprioli F, Sarra M, Fantini MC, Rizzo A, Pallone F, Monteleone G.

Biochem Pharmacol. 2008 Feb 1;75(3):668-76. Epub 2007 Sep 29.

PMID:
17981262
42.

IL-21 regulates experimental colitis by modulating the balance between Treg and Th17 cells.

Fantini MC, Rizzo A, Fina D, Caruso R, Becker C, Neurath MF, Macdonald TT, Pallone F, Monteleone G.

Eur J Immunol. 2007 Nov;37(11):3155-63.

43.

New players in the cytokine orchestra of inflammatory bowel disease.

Fantini MC, Monteleone G, Macdonald TT.

Inflamm Bowel Dis. 2007 Nov;13(11):1419-23. Review.

PMID:
17712836
44.

Cutting edge: trans-signaling via the soluble IL-6R abrogates the induction of FoxP3 in naive CD4+CD25 T cells.

Dominitzki S, Fantini MC, Neufert C, Nikolaev A, Galle PR, Scheller J, Monteleone G, Rose-John S, Neurath MF, Becker C.

J Immunol. 2007 Aug 15;179(4):2041-5.

45.

In vitro generation of CD4+ CD25+ regulatory cells from murine naive T cells.

Fantini MC, Dominitzki S, Rizzo A, Neurath MF, Becker C.

Nat Protoc. 2007;2(7):1789-94.

PMID:
17641646
46.

IL-27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1.

Neufert C, Becker C, Wirtz S, Fantini MC, Weigmann B, Galle PR, Neurath MF.

Eur J Immunol. 2007 Jul;37(7):1809-16.

47.

IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis.

Caruso R, Fina D, Peluso I, Fantini MC, Tosti C, Del Vecchio Blanco G, Paoluzi OA, Caprioli F, Andrei F, Stolfi C, Romano M, Ricci V, MacDonald TT, Pallone F, Monteleone G.

J Immunol. 2007 May 1;178(9):5957-65.

48.

High resolution colonoscopy in live mice.

Becker C, Fantini MC, Neurath MF.

Nat Protoc. 2006;1(6):2900-4.

PMID:
17406549
49.

Role of interleukin-21 in inflammation and allergy.

Fina D, Fantini MC, Pallone F, Monteleone G.

Inflamm Allergy Drug Targets. 2007 Mar;6(1):63-8. Review.

PMID:
17352690
50.

Lactobacillus paracasei subsp. paracasei B21060 suppresses human T-cell proliferation.

Peluso I, Fina D, Caruso R, Stolfi C, Caprioli F, Fantini MC, Caspani G, Grossi E, Di Iorio L, Paone FM, Pallone F, Monteleone G.

Infect Immun. 2007 Apr;75(4):1730-7. Epub 2007 Jan 22.

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