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Items: 45

1.

KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C.

Naiyer MM, Cassidy SA, Magri A, Cowton V, Chen K, Mansour S, Kranidioti H, Mbirbindi B, Rettman P, Harris S, Fanning LJ, Mulder A, Claas FHJ, Davidson AD, Patel AH, Purbhoo MA, Khakoo SI.

Sci Immunol. 2017 Sep 15;2(15). pii: eaal5296. doi: 10.1126/sciimmunol.aal5296.

PMID:
28916719
2.

Reverse epitope mapping of the E2 glycoprotein in antibody associated hepatitis C virus.

Naik AS, Owsianka A, Palmer BA, O'Halloran CJ, Walsh N, Crosbie O, Kenny-Walsh E, Patel AH, Fanning LJ.

PLoS One. 2017 May 30;12(5):e0175349. doi: 10.1371/journal.pone.0175349. eCollection 2017.

3.

Humoral immune system targets clonotypic antibody-associated hepatitis C virus.

Naik AS, Palmer BA, Crosbie O, Kenny-Walsh E, Fanning LJ.

J Gen Virol. 2017 Feb;98(2):179-189. doi: 10.1099/jgv.0.000659.

PMID:
28284234
4.

Effectiveness of interferon-free therapy for the treatment of HCV-patients with compensated cirrhosis treated through the Irish early access program.

Gray E, O'Leary A, Bergin C, Cannon M, Courtney G, Crosbie O, De Gascun CF, Fanning LJ, Feeney E, Houlihan DD, Kelleher B, Lambert JS, Lee J, Mallon P, McConkey S, McCormick A, McKiernan S, McNally C, Murray F, Sheehan G, Stewart S, Walsh C, Norris S; Irish Hepatitis C Outcomes and Research Network (ICORN).

Expert Rev Gastroenterol Hepatol. 2017 Jun;11(6):593-601. doi: 10.1080/17474124.2017.1292850. Epub 2017 Feb 22. Erratum in: Expert Rev Gastroenterol Hepatol. 2017 Jun;11(6):viii.

PMID:
28276815
5.

Hepatitis E Virus (HEV) Infection in Ireland.

Hickey C, Spillane D, Benson J, Levis J, Fanning LJ, Cryan B, Prentice MB.

Ir Med J. 2016 Sep 9;109(8):451.

PMID:
28124851
6.

Humoral immune system targets clonotypic antibody associated Hepatitis C Virus.

Naik AS, Palmer BA, Crossbie O, Kenny-Walsh E, Fanning LJ.

J Gen Virol. 2016 Nov 14. doi: 10.1099/jgv.0.000659. [Epub ahead of print]

PMID:
27902354
7.

Synonymous Co-Variation across the E1/E2 Gene Junction of Hepatitis C Virus Defines Virion Fitness.

Palmer BA, Fanning LJ.

PLoS One. 2016 Nov 23;11(11):e0167089. doi: 10.1371/journal.pone.0167089. eCollection 2016.

8.

High mortality during direct acting antiviral therapy for hepatitis C patients with Child's C cirrhosis: Results of the Irish Early Access Programme.

Gray E, O'Leary A, Stewart S, Bergin C, Cannon M, Courtney G, Crosbie O, De Gascun CF, Fanning LJ, Feeney E, Houlihan DD, Kelleher B, Lambert JS, Lee J, Mallon P, McConkey S, McCormick A, McKiernan S, McNally C, Murray F, Sheehan G, Norris S; Irish Hepatitis C Outcomes and Research Network (ICORN).

J Hepatol. 2016 Aug;65(2):446-8. doi: 10.1016/j.jhep.2016.03.022. Epub 2016 Apr 27. No abstract available.

PMID:
27130842
9.

A single amino acid change in the hypervariable region 1 of hepatitis C virus genotype 4a aids humoral immune escape.

Naik AS, Palmer BA, Crosbie O, Kenny-Walsh E, Fanning LJ.

J Gen Virol. 2016 Jun;97(6):1345-9. doi: 10.1099/jgv.0.000447. Epub 2016 Mar 4.

PMID:
26945008
10.

Network Analysis of the Chronic Hepatitis C Virome Defines Hypervariable Region 1 Evolutionary Phenotypes in the Context of Humoral Immune Responses.

Palmer BA, Schmidt-Martin D, Dimitrova Z, Skums P, Crosbie O, Kenny-Walsh E, Fanning LJ.

J Virol. 2015 Dec 30;90(7):3318-29. doi: 10.1128/JVI.02995-15.

11.

Hypermethylation of MAPK13 Promoter in Oesophageal Squamous Cell Carcinoma Is Associated with Loss of p38δ MAPK Expression.

O' Callaghan C, Fanning LJ, Barry OP.

Cancers (Basel). 2015 Oct 23;7(4):2124-33. doi: 10.3390/cancers7040881.

12.

Intensive temporal mapping of hepatitis C hypervariable region 1 quasispecies provides novel insights into hepatitis C virus evolution in chronic infection.

Schmidt-Martin D, Crosbie O, Kenny-Walsh E, Fanning LJ.

J Gen Virol. 2015 Aug;96(8):2145-56. doi: 10.1099/vir.0.000149. Epub 2015 Apr 15.

PMID:
25877936
13.

Engagement of Fas on Macrophages Modulates Poly I:C induced cytokine production with specific enhancement of IP-10.

Lyons C, Fernandes P, Fanning LJ, Houston A, Brint E.

PLoS One. 2015 Apr 7;10(4):e0123635. doi: 10.1371/journal.pone.0123635. eCollection 2015.

14.

p38δ MAPK: Emerging Roles of a Neglected Isoform.

O'Callaghan C, Fanning LJ, Barry OP.

Int J Cell Biol. 2014;2014:272689. doi: 10.1155/2014/272689. Epub 2014 Sep 17. Review.

15.

Analysis of the evolution and structure of a complex intrahost viral population in chronic hepatitis C virus mapped by ultradeep pyrosequencing.

Palmer BA, Dimitrova Z, Skums P, Crosbie O, Kenny-Walsh E, Fanning LJ.

J Virol. 2014 Dec;88(23):13709-21. doi: 10.1128/JVI.01732-14. Epub 2014 Sep 17.

16.

p38δ MAPK phenotype: an indicator of chemotherapeutic response in oesophageal squamous cell carcinoma.

O'Callaghan C, Fanning LJ, Barry OP.

Anticancer Drugs. 2015 Jan;26(1):46-55. doi: 10.1097/CAD.0000000000000156.

17.

Loss of p38δ mitogen-activated protein kinase expression promotes oesophageal squamous cell carcinoma proliferation, migration and anchorage-independent growth.

O'Callaghan C, Fanning LJ, Houston A, Barry OP.

Int J Oncol. 2013 Aug;43(2):405-15. doi: 10.3892/ijo.2013.1968. Epub 2013 May 29.

18.

Constraints on viral evolution during chronic hepatitis C virus infection arising from a common-source exposure.

Bailey JR, Laskey S, Wasilewski LN, Munshaw S, Fanning LJ, Kenny-Walsh E, Ray SC.

J Virol. 2012 Dec;86(23):12582-90. doi: 10.1128/JVI.01440-12. Epub 2012 Sep 12.

19.

Insertion and recombination events at hypervariable region 1 over 9.6 years of hepatitis C virus chronic infection.

Palmer BA, Moreau I, Levis J, Harty C, Crosbie O, Kenny-Walsh E, Fanning LJ.

J Gen Virol. 2012 Dec;93(Pt 12):2614-24. doi: 10.1099/vir.0.045344-0. Epub 2012 Sep 12.

PMID:
22971825
20.

The pan-genotype specificity of the hepatitis C virus anti-core monoclonal antibody C7-50 is contingent on the quasispecies profile of a population.

Palmer BA, Menton J, Levis J, Kenny-Walsh E, Crosbie O, Fanning LJ.

Arch Virol. 2012 Nov;157(11):2235-9. doi: 10.1007/s00705-012-1418-4. Epub 2012 Jul 25.

PMID:
22828781
21.

Clinical relevance of detectable hepatitis C virus RNA in the context of direct-acting antivirals.

O'Sullivan K, Levis J, Hegarty K, Crosbie O, Kenny-Walsh E, Fanning LJ.

Hepatology. 2013 Feb;57(2):855-6. doi: 10.1002/hep.25942. No abstract available.

PMID:
22806480
22.

The prevalence and genotype of human papillomavirus on cervical samples from an Irish female population with external genital warts.

Cremin S, Menton JF, Canier L, Horgan M, Fanning LJ.

Hum Vaccin Immunother. 2012 Jul;8(7):916-20. doi: 10.4161/hv.20122. Epub 2012 Jul 1.

PMID:
22777095
23.

Molecular epidemiology of sexually transmitted human papillomavirus in a self referred group of women in Ireland.

Menton JF, Cremin SM, Canier L, Horgan M, Fanning LJ.

Virol J. 2009 Jul 23;6:112. doi: 10.1186/1743-422X-6-112.

24.

Histological changes in hepatitis C virus antibody-positive, hepatitis C virus RNA-negative subjects suggest persistent virus infection.

Moreau I, Kenny-Walsh E, Crosbie O, Fanning LJ.

Hepatology. 2009 Apr;49(4):1392; author reply 1392-3. doi: 10.1002/hep.22799. No abstract available.

PMID:
19263470
25.

Use of an autologous blood recovery system during emergency pericardiocentesis in the electrophysiology laboratory.

Venkatachalam KL, Fanning LJ, Willis EA, Beinborn DS, Bradley DJ, Cha YM, Shen WK, Asirvatham SJ, Sinak LJ, Packer DL, Munger TM, Santrach PJ, Friedman PA.

J Cardiovasc Electrophysiol. 2009 Mar;20(3):280-3. doi: 10.1111/j.1540-8167.2008.01313.x.

PMID:
19261039
26.

Molecular epidemiology and interferon susceptibility of the natural recombinant hepatitis C virus strain RF1_2k/1b.

Kurbanov F, Tanaka Y, Chub E, Maruyama I, Azlarova A, Kamitsukasa H, Ohno T, Bonetto S, Moreau I, Fanning LJ, Legrand-Abravanel F, Izopet J, Naoumov N, Shimada T, Netesov S, Mizokami M.

J Infect Dis. 2008 Nov 15;198(10):1448-56. doi: 10.1086/592757.

PMID:
18928375
27.

Separation of Hepatitis C genotype 4a into IgG-depleted and IgG-enriched fractions reveals a unique quasispecies profile.

Moreau I, O'Sullivan H, Murray C, Levis J, Crosbie O, Kenny-Walsh E, Fanning LJ.

Virol J. 2008 Sep 23;5:103. doi: 10.1186/1743-422X-5-103.

28.

Practical consequences of hepatitis C virus quasispecies for target-specific antivirals.

Fanning LJ.

J Infect Dis. 2008 Sep 15;198(6):797-9. doi: 10.1086/591142. No abstract available.

PMID:
18637751
29.

Correlation between pre-treatment quasispecies complexity and treatment outcome in chronic HCV genotype 3a.

Moreau I, Levis J, Crosbie O, Kenny-Walsh E, Fanning LJ.

Virol J. 2008 Jul 9;5:78. doi: 10.1186/1743-422X-5-78.

30.

In vitro replication models for the hepatitis C virus.

Sheehy P, Mullan B, Moreau I, Kenny-Walsh E, Shanahan F, Scallan M, Fanning LJ.

J Viral Hepat. 2007 Jan;14(1):2-10. Review.

PMID:
17212638
31.

Serendipitous identification of natural intergenotypic recombinants of hepatitis C in Ireland.

Moreau I, Hegarty S, Levis J, Sheehy P, Crosbie O, Kenny-Walsh E, Fanning LJ.

Virol J. 2006 Nov 15;3:95.

32.

Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated anti-D immunoglobulin*.

Itakura J, Nagayama K, Enomoto N, Hamano K, Sakamoto N, Fanning LJ, Kenny-Walsh E, Shanahan F, Watanabe M.

J Viral Hepat. 2005 Nov;12(6):594-603.

PMID:
16255760
33.

Hepatitis B genotype and YMDD profiles in an untreated Irish population.

Horgan M, Brannigan E, Crowley B, Levis J, Fanning LJ.

J Clin Virol. 2006 Feb;35(2):203-4. Epub 2005 Oct 6. No abstract available.

PMID:
16213785
34.

A strategy for obtaining near full-length HCV cDNA clones (assemblicons) by assembly PCR.

Sheehy P, Scallan M, Kenny-Walsh E, Shanahan F, Fanning LJ.

J Virol Methods. 2005 Feb;123(2):115-24.

PMID:
15620392
35.

Persistence of hepatitis C virus in a white population: associations with human leukocyte antigen class 1.

Fanning LJ, Kenny-Walsh E, Shanahan F.

Hum Immunol. 2004 Jul;65(7):745-51.

PMID:
15301865
36.

RT-PCR for the assessment of genetically heterogenous populations of the hepatitis C virus.

Mullan B, Fanning LJ, Shanahan F, Sullivan DG.

Methods Mol Biol. 2002;193:171-88. No abstract available.

PMID:
12325507
37.

Detection and quantification of the hepatitis C viral genome.

Fanning LJ.

Methods Mol Biol. 2002;193:151-60. No abstract available.

PMID:
12325505
39.

Inferred hepatitis C virus quasispecies diversity is influenced by choice of DNA polymerase in reverse transcriptase-polymerase chain reactions.

Mullan B, Kenny-Walsh E, Collins JK, Shanahan F, Fanning LJ.

Anal Biochem. 2001 Feb 15;289(2):137-46.

PMID:
11161307
40.

HLA class II genes determine the natural variance of hepatitis C viral load.

Fanning LJ, Levis J, Kenny-Walsh E, Whelton M, O'Sullivan K, Shanahan F.

Hepatology. 2001 Jan;33(1):224-30.

PMID:
11124840
41.

Viral clearance in hepatitis C (1b) infection: relationship with human leukocyte antigen class II in a homogeneous population.

Fanning LJ, Levis J, Kenny-Walsh E, Wynne F, Whelton M, Shanahan F.

Hepatology. 2000 Jun;31(6):1334-7.

PMID:
10827160
42.

Development of the immunoglobulin repertoire.

Fanning LJ, Connor AM, Wu GE.

Clin Immunol Immunopathol. 1996 Apr;79(1):1-14. Review.

PMID:
8612345
43.

Mouse VH7183 recombination signal sequences mediate recombination more frequently than those of VHJ558.

Connor AM, Fanning LJ, Celler JW, Hicks LK, Ramsden DA, Wu GE.

J Immunol. 1995 Dec 1;155(11):5268-72.

PMID:
7594539
44.

A shuttle vector system for the rapid detection of recombination in murine cells.

Fanning LJ, McCarthy TV.

Nucleic Acids Res. 1993 Nov 25;21(23):5530-1. No abstract available.

45.

Class-switch recombination in extrachromosomal DNA substrates in murine pre-B-cells.

Fanning LJ, O'Regan E, McCarthy S, McCarthy TV.

Biochem Soc Trans. 1990 Apr;18(2):356-7. No abstract available.

PMID:
2199278

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