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Items: 15

1.

Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.

Just S, Chenard BL, Ceci A, Strassmaier T, Chong JA, Blair NT, Gallaschun RJ, Del Camino D, Cantin S, D'Amours M, Eickmeier C, Fanger CM, Hecker C, Hessler DP, Hengerer B, Kroker KS, Malekiani S, Mihalek R, McLaughlin J, Rast G, Witek J, Sauer A, Pryce CR, Moran MM.

PLoS One. 2018 Jan 31;13(1):e0191225. doi: 10.1371/journal.pone.0191225. eCollection 2018.

2.

MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.

Volkmann RA, Fanger CM, Anderson DR, Sirivolu VR, Paschetto K, Gordon E, Virginio C, Gleyzes M, Buisson B, Steidl E, Mierau SB, Fagiolini M, Menniti FS.

PLoS One. 2016 Feb 1;11(2):e0148129. doi: 10.1371/journal.pone.0148129. eCollection 2016. Erratum in: PLoS One. 2016;11(3):e0151452.

3.

TRPA1 contributes to cold hypersensitivity.

del Camino D, Murphy S, Heiry M, Barrett LB, Earley TJ, Cook CA, Petrus MJ, Zhao M, D'Amours M, Deering N, Brenner GJ, Costigan M, Hayward NJ, Chong JA, Fanger CM, Woolf CJ, Patapoutian A, Moran MM.

J Neurosci. 2010 Nov 10;30(45):15165-74. doi: 10.1523/JNEUROSCI.2580-10.2010.

4.

Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.

Everaerts W, Zhen X, Ghosh D, Vriens J, Gevaert T, Gilbert JP, Hayward NJ, McNamara CR, Xue F, Moran MM, Strassmaier T, Uykal E, Owsianik G, Vennekens R, De Ridder D, Nilius B, Fanger CM, Voets T.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19084-9. doi: 10.1073/pnas.1005333107. Epub 2010 Oct 18.

5.

A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma.

Caceres AI, Brackmann M, Elia MD, Bessac BF, del Camino D, D'Amours M, Witek JS, Fanger CM, Chong JA, Hayward NJ, Homer RJ, Cohn L, Huang X, Moran MM, Jordt SE.

Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9099-104. doi: 10.1073/pnas.0900591106. Epub 2009 May 19.

6.

TRPA1 mediates formalin-induced pain.

McNamara CR, Mandel-Brehm J, Bautista DM, Siemens J, Deranian KL, Zhao M, Hayward NJ, Chong JA, Julius D, Moran MM, Fanger CM.

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13525-30. Epub 2007 Aug 8.

7.

Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels.

Fanger CM, Rauer H, Neben AL, Miller MJ, Rauer H, Wulff H, Rosa JC, Ganellin CR, Chandy KG, Cahalan MD.

J Biol Chem. 2001 Apr 13;276(15):12249-56. Epub 2001 Jan 22.

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Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice.

Leissring MA, Akbari Y, Fanger CM, Cahalan MD, Mattson MP, LaFerla FM.

J Cell Biol. 2000 May 15;149(4):793-8.

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Calmodulin mediates calcium-dependent activation of the intermediate conductance KCa channel, IKCa1.

Fanger CM, Ghanshani S, Logsdon NJ, Rauer H, Kalman K, Zhou J, Beckingham K, Chandy KG, Cahalan MD, Aiyar J.

J Biol Chem. 1999 Feb 26;274(9):5746-54.

13.

A nongenomic mechanism for progesterone-mediated immunosuppression: inhibition of K+ channels, Ca2+ signaling, and gene expression in T lymphocytes.

Ehring GR, Kerschbaum HH, Eder C, Neben AL, Fanger CM, Khoury RM, Negulescu PA, Cahalan MD.

J Exp Med. 1998 Nov 2;188(9):1593-602.

14.

Mitochondrial regulation of store-operated calcium signaling in T lymphocytes.

Hoth M, Fanger CM, Lewis RS.

J Cell Biol. 1997 May 5;137(3):633-48.

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