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Items: 23


Genetic basis of PD-L1 overexpression in diffuse large B-cell lymphomas.

Georgiou K, Chen L, Berglund M, Ren W, de Miranda NF, Lisboa S, Fangazio M, Zhu S, Hou Y, Wu K, Fang W, Wang X, Meng B, Zhang L, Zeng Y, Bhagat G, Nordenskjöld M, Sundström C, Enblad G, Dalla-Favera R, Zhang H, Teixeira MR, Pasqualucci L, Peng R, Pan-Hammarström Q.

Blood. 2016 Jun 16;127(24):3026-34. doi: 10.1182/blood-2015-12-686550. Epub 2016 Mar 30.


Genetics of follicular lymphoma transformation.

Pasqualucci L, Khiabanian H, Fangazio M, Vasishtha M, Messina M, Holmes AB, Ouillette P, Trifonov V, Rossi D, Tabbò F, Ponzoni M, Chadburn A, Murty VV, Bhagat G, Gaidano G, Inghirami G, Malek SN, Rabadan R, Dalla-Favera R.

Cell Rep. 2014 Jan 16;6(1):130-40. doi: 10.1016/j.celrep.2013.12.027. Epub 2014 Jan 2.


The spectrum of genetic defects in chronic lymphocytic leukemia.

Rossi D, Fangazio M, Gaidano G.

Mediterr J Hematol Infect Dis. 2012;4(1):e2012076. doi: 10.4084/MJHID.2012.076. Epub 2012 Nov 13.


The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.

Rossi D, Trifonov V, Fangazio M, Bruscaggin A, Rasi S, Spina V, Monti S, Vaisitti T, Arruga F, Famà R, Ciardullo C, Greco M, Cresta S, Piranda D, Holmes A, Fabbri G, Messina M, Rinaldi A, Wang J, Agostinelli C, Piccaluga PP, Lucioni M, Tabbò F, Serra R, Franceschetti S, Deambrogi C, Daniele G, Gattei V, Marasca R, Facchetti F, Arcaini L, Inghirami G, Bertoni F, Pileri SA, Deaglio S, Foà R, Dalla-Favera R, Pasqualucci L, Rabadan R, Gaidano G.

J Exp Med. 2012 Aug 27;209(9):1537-51. doi: 10.1084/jem.20120904. Epub 2012 Aug 13.


The genome of chemorefractory chronic lymphocytic leukemia reveals frequent mutations of NOTCH1 and SF3B1.

Rossi D, Rasi S, Spina V, Bruscaggin A, Monti S, Cresta S, Famà R, Deambrogi C, Greco M, Fangazio M, Ciardullo C, Piranda D, Casaluci GM, Messina M, Giudice ID, Chiaretti S, Marinelli M, Guarini A, Foà R, Gaidano G.

Leuk Suppl. 2012 Aug;1(Suppl 2):S26-8. doi: 10.1038/leusup.2012.16. Epub 2012 Aug 9.


Different impact of NOTCH1 and SF3B1 mutations on the risk of chronic lymphocytic leukemia transformation to Richter syndrome.

Rossi D, Rasi S, Spina V, Fangazio M, Monti S, Greco M, Ciardullo C, Famà R, Cresta S, Bruscaggin A, Laurenti L, Martini M, Musto P, Forconi F, Marasca R, Larocca LM, Foà R, Gaidano G.

Br J Haematol. 2012 Aug;158(3):426-9. doi: 10.1111/j.1365-2141.2012.09155.x. Epub 2012 May 10. No abstract available.


Analysis of SF3B1 mutations in monoclonal B-cell lymphocytosis.

Greco M, Capello D, Bruscaggin A, Spina V, Rasi S, Monti S, Ciardullo C, Cresta S, Fangazio M, Gaidano G, Foà R, Rossi D.

Hematol Oncol. 2013 Mar;31(1):54-5. doi: 10.1002/hon.2013. Epub 2012 Mar 29. No abstract available.


Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia.

Rossi D, Fangazio M, Rasi S, Vaisitti T, Monti S, Cresta S, Chiaretti S, Del Giudice I, Fabbri G, Bruscaggin A, Spina V, Deambrogi C, Marinelli M, Famà R, Greco M, Daniele G, Forconi F, Gattei V, Bertoni F, Deaglio S, Pasqualucci L, Guarini A, Dalla-Favera R, Foà R, Gaidano G.

Blood. 2012 Mar 22;119(12):2854-62. doi: 10.1182/blood-2011-12-395673. Epub 2012 Feb 3.


NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL.

Del Giudice I, Rossi D, Chiaretti S, Marinelli M, Tavolaro S, Gabrielli S, Laurenti L, Marasca R, Rasi S, Fangazio M, Guarini A, Gaidano G, Foà R.

Haematologica. 2012 Mar;97(3):437-41. doi: 10.3324/haematol.2011.060129. Epub 2011 Dec 29.


Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia.

Rossi D, Rasi S, Fabbri G, Spina V, Fangazio M, Forconi F, Marasca R, Laurenti L, Bruscaggin A, Cerri M, Monti S, Cresta S, Famà R, De Paoli L, Bulian P, Gattei V, Guarini A, Deaglio S, Capello D, Rabadan R, Pasqualucci L, Dalla-Favera R, Foà R, Gaidano G.

Blood. 2012 Jan 12;119(2):521-9. doi: 10.1182/blood-2011-09-379966. Epub 2011 Nov 10.


Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness.

Rossi D, Bruscaggin A, Spina V, Rasi S, Khiabanian H, Messina M, Fangazio M, Vaisitti T, Monti S, Chiaretti S, Guarini A, Del Giudice I, Cerri M, Cresta S, Deambrogi C, Gargiulo E, Gattei V, Forconi F, Bertoni F, Deaglio S, Rabadan R, Pasqualucci L, Foà R, Dalla-Favera R, Gaidano G.

Blood. 2011 Dec 22;118(26):6904-8. doi: 10.1182/blood-2011-08-373159. Epub 2011 Oct 28.


Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma.

Rossi D, Deaglio S, Dominguez-Sola D, Rasi S, Vaisitti T, Agostinelli C, Spina V, Bruscaggin A, Monti S, Cerri M, Cresta S, Fangazio M, Arcaini L, Lucioni M, Marasca R, Thieblemont C, Capello D, Facchetti F, Kwee I, Pileri SA, Foà R, Bertoni F, Dalla-Favera R, Pasqualucci L, Gaidano G.

Blood. 2011 Nov 3;118(18):4930-4. doi: 10.1182/blood-2011-06-359166. Epub 2011 Aug 31.


Molecular history of Richter syndrome: origin from a cell already present at the time of chronic lymphocytic leukemia diagnosis.

Rossi D, Spina V, Forconi F, Capello D, Fangazio M, Rasi S, Martini M, Gattei V, Ramponi A, Larocca LM, Bertoni F, Gaidano G.

Int J Cancer. 2012 Jun 15;130(12):3006-10. doi: 10.1002/ijc.26322. Epub 2011 Aug 25.


Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.

Fabbri G, Rasi S, Rossi D, Trifonov V, Khiabanian H, Ma J, Grunn A, Fangazio M, Capello D, Monti S, Cresta S, Gargiulo E, Forconi F, Guarini A, Arcaini L, Paulli M, Laurenti L, Larocca LM, Marasca R, Gattei V, Oscier D, Bertoni F, Mullighan CG, Foá R, Pasqualucci L, Rabadan R, Dalla-Favera R, Gaidano G.

J Exp Med. 2011 Jul 4;208(7):1389-401. doi: 10.1084/jem.20110921. Epub 2011 Jun 13.


Saliva is a reliable and practical source of germline DNA for genome-wide studies in chronic lymphocytic leukemia.

Rasi S, Bruscaggin A, Rinaldi A, Cresta S, Fangazio M, De Paoli L, Monti S, Gargiulo E, Kwee I, Foà R, Bertoni F, Gaidano G, Rossi D.

Leuk Res. 2011 Oct;35(10):1419-22. doi: 10.1016/j.leukres.2011.05.024. Epub 2011 Jun 12.


Predictive markers and driving factors behind Richter syndrome development.

Fangazio M, De Paoli L, Rossi D, Gaidano G.

Expert Rev Anticancer Ther. 2011 Mar;11(3):433-42. doi: 10.1586/era.10.237. Review.


The host genetic background of DNA repair mechanisms is an independent predictor of survival in diffuse large B-cell lymphoma.

Rossi D, Rasi S, Di Rocco A, Fabbri A, Forconi F, Gloghini A, Bruscaggin A, Franceschetti S, Fangazio M, De Paoli L, Bruna R, Capello D, Chiappella A, Lobetti Bodoni C, Giachelia M, Tisi MC, Pogliani EM, Lauria F, Ladetto M, Hohaus S, Martelli M, Vitolo U, Carbone A, Foà R, Gaidano G.

Blood. 2011 Feb 24;117(8):2405-13. doi: 10.1182/blood-2010-07-296244. Epub 2010 Dec 14.


A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome.

Rasi S, Spina V, Bruscaggin A, Vaisitti T, Tripodo C, Forconi F, De Paoli L, Fangazio M, Sozzi E, Cencini E, Laurenti L, Marasca R, Visco C, Xu-Monette ZY, Gattei V, Young KH, Malavasi F, Deaglio S, Gaidano G, Rossi D.

Br J Haematol. 2011 Feb;152(3):284-94. doi: 10.1111/j.1365-2141.2010.08482.x. Epub 2010 Dec 1.


Low CD49d expression and long telomere identify a chronic lymphocytic leukemia subset with highly favourable outcome.

Rossi D, Bodoni CL, Zucchetto A, Rasi S, De Paoli L, Fangazio M, Rossi FM, Ladetto M, Gattei V, Gaidano G.

Am J Hematol. 2010 Aug;85(8):619-22. doi: 10.1002/ajh.21756. No abstract available.


Analysis of the REL, BCL11A, and MYCN proto-oncogenes belonging to the 2p amplicon in chronic lymphocytic leukemia.

Deambrogi C, De Paoli L, Fangazio M, Cresta S, Rasi S, Spina V, Gattei V, Gaidano G, Rossi D.

Am J Hematol. 2010 Jul;85(7):541-4. doi: 10.1002/ajh.21742. No abstract available.


BCL3 translocation in CLL with typical phenotype: assessment of frequency, association with cytogenetic subgroups, and prognostic significance.

Rossi D, Deambrogi C, Monti S, Cresta S, De Paoli L, Fangazio M, Giardini I, Bernasconi P, Gaidano G.

Br J Haematol. 2010 Sep;150(6):702-4. doi: 10.1111/j.1365-2141.2010.08255.x. No abstract available.


Prognostic impact of ZAP-70 expression in chronic lymphocytic leukemia: mean fluorescence intensity T/B ratio versus percentage of positive cells.

Rossi FM, Del Principe MI, Rossi D, Irno Consalvo M, Luciano F, Zucchetto A, Bulian P, Bomben R, Dal Bo M, Fangazio M, Benedetti D, Degan M, Gaidano G, Del Poeta G, Gattei V.

J Transl Med. 2010 Mar 8;8:23. doi: 10.1186/1479-5876-8-23.


Beta-2-microglobulin is an independent predictor of progression in asymptomatic multiple myeloma.

Rossi D, Fangazio M, De Paoli L, Puma A, Riccomagno P, Pinto V, Zigrossi P, Ramponi A, Monga G, Gaidano G.

Cancer. 2010 May 1;116(9):2188-200. doi: 10.1002/cncr.24959.

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