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Design, synthesis and biological evaluation of tyrosine derivatives as Mcl-1 inhibitors.

Liu L, Liu R, Yang X, Hou X, Fang H.

Eur J Med Chem. 2020 Feb 14;191:112142. doi: 10.1016/j.ejmech.2020.112142. [Epub ahead of print]


Systematic Use of Fluorescence in situ Hybridization (FISH) and Clinicopathological Features in the Screening of PDGFRB Rearrangements of Patients with Myeloid/Lymphoid Neoplasms.

Fang H, Tang G, Loghavi S, Greipp P, Wang W, Verstovsek S, Medeiros LJ, Reichard K, Miranda RN, Wang SA.

Histopathology. 2020 Feb 21. doi: 10.1111/his.14097. [Epub ahead of print]


Inhibition of striatal-enriched protein tyrosine phosphatase by targeting computationally revealed cryptic pockets.

Hou X, Sun JP, Ge L, Liang X, Li K, Zhang Y, Fang H.

Eur J Med Chem. 2020 Feb 11;190:112131. doi: 10.1016/j.ejmech.2020.112131. [Epub ahead of print]


Rational Design of Two-photon Fluorogenic Probe for Visualizing Monoamine Oxidase A Activity in Human Glioma Tissues.

Fang H, Zhang H, Li L, Ni Y, Shi R, Li Z, Yang X, Ma B, Zhang C, Wu Q, Yu C, Yang N, Yao SQ, Huang W.

Angew Chem Int Ed Engl. 2020 Feb 19. doi: 10.1002/anie.202000059. [Epub ahead of print]


Inhibition mechanism of ferulic acid against α-amylase and α-glucosidase.

Zheng Y, Tian J, Yang W, Chen S, Liu D, Fang H, Zhang H, Ye X.

Food Chem. 2020 Feb 3;317:126346. doi: 10.1016/j.foodchem.2020.126346. [Epub ahead of print]


Disease characteristics and treatment patterns of Chinese patients with metastatic colorectal cancer: a retrospective study using medical records from China.

Xu R, Wang W, Zhu B, Lin X, Ma D, Zhu L, Zhao Q, Nie Y, Cai X, Li Q, Fang W, Li H, Wang N, Chen Y, Peng C, Fang H, Shen L.

BMC Cancer. 2020 Feb 18;20(1):131. doi: 10.1186/s12885-020-6557-5.


All-in-One Hydrogel Realizing Adipose Derived Stem Cell Spheroids Production and in Vivo Injection via "Gel-Sol" Transition for Angiogenesis in Hind Limb Ischemia.

Hong Y, Chen J, Fang H, Li G, Yan S, Zhang K, Wang C, Yin J.

ACS Appl Mater Interfaces. 2020 Feb 18. doi: 10.1021/acsami.9b23534. [Epub ahead of print]


Chalcomoracin inhibits cell proliferation and increases sensitivity to radiotherapy in human non-small cell lung cancer cells via inducing endoplasmic reticulum stress-mediated paraptosis.

Zhang SR, Zhang XC, Liang JF, Fang HM, Huang HX, Zhao YY, Chen XQ, Ma SL.

Acta Pharmacol Sin. 2020 Feb 17. doi: 10.1038/s41401-019-0351-4. [Epub ahead of print]


The ELISA Detectability and Potency of Pegfilgrastim Decrease in Physiological Conditions: Key Roles for Aggregation and Individual Variability.

Xie T, Fang H, Ouyang W, Angart P, Chiang MJ, Bhirde AA, Sheikh F, Lynch P, Shah AB, Patil SM, Chen K, Shen M, Agarabi C, Donnelly RP, Brorson K, Schrieber SJ, Howard KE, Rogstad SM, Frucht DM.

Sci Rep. 2020 Feb 12;10(1):2476. doi: 10.1038/s41598-020-59346-z.


An interspecific variation in rhizosphere effects on soil anti-erodibility.

Wang Z, Chiarucci A, Fang H, Chen M.

Sci Rep. 2020 Feb 12;10(1):2411. doi: 10.1038/s41598-020-58784-z.


Parathyromatosis type 2 detected by 99mTc-MIBI SPECT/CT.

Cao H, Zeng M, Fang H, Tang L, Liu W.

Gland Surg. 2019 Dec;8(6):806-809. doi: 10.21037/gs.2019.11.13.


Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma.

Fairfax BP, Taylor CA, Watson RA, Nassiri I, Danielli S, Fang H, Mahé EA, Cooper R, Woodcock V, Traill Z, Al-Mossawi MH, Knight JC, Klenerman P, Payne M, Middleton MR.

Nat Med. 2020 Feb;26(2):193-199. doi: 10.1038/s41591-019-0734-6. Epub 2020 Feb 10.


Erk1/2 inactivation promotes a rapid redistribution of COP1 and degradation of COP1 substrates.

Ouyang W, Guo P, Takeda K, Fu Q, Fang H, Frucht DM.

Proc Natl Acad Sci U S A. 2020 Feb 10. pii: 201913698. doi: 10.1073/pnas.1913698117. [Epub ahead of print]


Study of pharmacogenomic information in FDA-approved drug labeling to facilitate application of precision medicine.

Mehta D, Uber R, Ingle T, Li C, Liu Z, Thakkar S, Ning B, Wu L, Yang J, Harris S, Zhou G, Xu J, Tong W, Lesko L, Fang H.

Drug Discov Today. 2020 Feb 4. pii: S1359-6446(20)30049-0. doi: 10.1016/j.drudis.2020.01.023. [Epub ahead of print]


A self-emulsifying formulation of Sonchus oleraceus Linn for an improved anti-diabetic effect in vivo.

Chen L, Lin X, Fan X, Lv Q, Fang H, Chenchen Y, Teng H.

Food Funct. 2020 Feb 7. doi: 10.1039/c9fo00772e. [Epub ahead of print]


Correction: An electroporation-free method based on Red recombineering for markerless deletion and genomic replacement in the Escherichia coli DH1 genome.

Wei Y, Deng P, Mohsin A, Yang Y, Zhou H, Guo M, Fang H.

PLoS One. 2020 Feb 6;15(2):e0229072. doi: 10.1371/journal.pone.0229072. eCollection 2020.


[A review of immune-related adverse events associated with immunotherapy].

Fang Y, Yu Y, Wu DW, Fang H, Huang HY, Wang SH, Yu AQ, Sun C, Bai Y, Wang H, Li N.

Zhonghua Zhong Liu Za Zhi. 2020 Jan 23;42(1):17-21. doi: 10.3760/cma.j.issn.0253-3766.2020.01.002. Chinese.


Effects of cationic concentration on controlling the interlayer spacings for highly effective ion rejection via graphene oxide membranes.

Wang S, Liang S, Chen L, Mu L, Xu G, Fang H.

Chem Commun (Camb). 2020 Feb 5. doi: 10.1039/c9cc08039b. [Epub ahead of print]


Impact of baseline characteristics on glycemic effects of add-on saxagliptin or acarbose to metformin therapy: subgroup analysis of the SMART study in Chinese patients with type 2 diabetes mellitus.

Fang H, Xu F, Du J, Liang L, Li W, Shen L, Wang X, Xu C, Bian F, Mu Y.

J Diabetes Investig. 2020 Feb 4. doi: 10.1111/jdi.13224. [Epub ahead of print]


Record-high stability and compactness of multiply-charged clusters aided by selected terminal groups.

Zhong MM, Fang H, Jena P.

Phys Chem Chem Phys. 2020 Feb 4. doi: 10.1039/c9cp06215g. [Epub ahead of print]


Small RNA Sequencing Reveals Exosomal miRNAs Involved in the Treatment of Asthma by Scorpio and Centipede.

Tang B, Wu Y, Fang H, Wu Y, Shi K.

Biomed Res Int. 2020 Jan 16;2020:1061407. doi: 10.1155/2020/1061407. eCollection 2020.


Sexually Dimorphic Effects of Dietary Methionine Restriction are Dependent on Age when the Diet is Introduced.

Forney LA, Stone KP, Gibson AN, Vick AM, Sims LC, Fang H, Gettys TW.

Obesity (Silver Spring). 2020 Mar;28(3):581-589. doi: 10.1002/oby.22721. Epub 2020 Feb 3.


Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer.

Fang H, Barbour JA, Poulos RC, Katainen R, Aaltonen LA, Wong JWH.

PLoS Genet. 2020 Feb 3;16(2):e1008572. doi: 10.1371/journal.pgen.1008572. eCollection 2020 Feb.


Availability of anticancer biosimilars in 40 countries.

Huang HY, Wu DW, Ma F, Liu ZL, Shi JF, Chen X, Wang SH, Fang H, Bai Y, Yu Y, Fang Y, Sun C, Fan Q, Wu Y, Fan RH, Zhou CY, He BX, Dai M, Li N, Xu BH, Sun Y, He J.

Lancet Oncol. 2020 Feb;21(2):197-201. doi: 10.1016/S1470-2045(19)30860-5. No abstract available.


Ultraviolet B-induced MdWRKY72 expression promotes anthocyanin synthesis in apple.

Hu J, Fang H, Wang J, Yue X, Su M, Mao Z, Zou Q, Jiang H, Guo Z, Yu L, Feng T, Lu L, Peng Z, Zhang Z, Wang N, Chen X.

Plant Sci. 2020 Mar;292:110377. doi: 10.1016/j.plantsci.2019.110377. Epub 2020 Jan 13.


Subcellular distribution governing accumulation and translocation of pesticides in wheat (Triticum aestivum L.).

Ju C, Dong S, Zhang H, Yao S, Wang F, Cao D, Xu S, Fang H, Yu Y.

Chemosphere. 2020 Jan 24;248:126024. doi: 10.1016/j.chemosphere.2020.126024. [Epub ahead of print]


Ascorbate and Iron Are Required for the Specification and Long-Term Self-Renewal of Human Skeletal Mesenchymal Stromal Cells.

Liu TM, Yildirim ED, Li P, Fang HT, Denslin V, Kumar V, Loh YH, Lee EH, Cool SM, Teh BT, Hui JH, Lim B, Shyh-Chang N.

Stem Cell Reports. 2020 Feb 11;14(2):210-225. doi: 10.1016/j.stemcr.2020.01.002. Epub 2020 Jan 30.


Giant Emission Enhancement of Solid-State Gold Nanoclusters by Surface Engineering.

Yao C, Xu CQ, Park IH, Zhao M, Zhu Z, Li J, Hai X, Fang H, Zhang Y, Macam G, Teng J, Li L, Xu QH, Chuang FC, Lu J, Su C, Li J, Lu J.

Angew Chem Int Ed Engl. 2020 Jan 30. doi: 10.1002/anie.202001034. [Epub ahead of print]


Screening of an alkaline CMCase-producing strain and the optimization of its fermentation condition.

Zhou J, Yin L, Wu C, Wu S, Lu J, Fang H, Qian Y.

Curr Pharm Biotechnol. 2020 Jan 29. doi: 10.2174/1389201021666200129123818. [Epub ahead of print]


Evaluation of 2 Rat Models for Sepsis Developed by Improved Cecal Ligation/Puncture or Feces Intraperitoneal-Injection.

Fang H, Gong C, Fu J, Liu X, Bi H, Cheng Y, Liu Y, Tang Y, Wang D.

Med Sci Monit. 2020 Jan 29;26:e919054. doi: 10.12659/MSM.919054.


Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.

Wei K, Dai J, Wang Z, Pei Y, Chen Y, Ding Y, Ding Q, Ahati P, Zhou X, Wang H, Fang H.

Exp Biol Med (Maywood). 2020 Jan 24:1535370219900773. doi: 10.1177/1535370219900773. [Epub ahead of print] No abstract available.


Method for Establishing Continuous Reinfusion of Succus Entericus in Complex High-output Fistula.

Niu DG, Yang F, Tian WL, Huang Q, Zhao YZ, Li C, Ding LA, Fang HC.

Surg Laparosc Endosc Percutan Tech. 2020 Jan 21. doi: 10.1097/SLE.0000000000000757. [Epub ahead of print]


Multi-stage surgery combined with radiotherapy for treatment of giant anterior chest wall keloid: A case report.

Liu Q, Li P, Yang Z, Qu B, Qin C, Meng S, Fang H, Wu R, Cheng T, Yang D.

Medicine (Baltimore). 2020 Jan;99(4):e18886. doi: 10.1097/MD.0000000000018886.


Genetic Factors in Acute Myeloid Leukemia With Myelodysplasia-Related Changes.

Fang H, He R, Chiu A, Viswanatha DS, Ketterling RP, Patnaik MS, Reichard KK.

Am J Clin Pathol. 2020 Jan 16. pii: aqz206. doi: 10.1093/ajcp/aqz206. [Epub ahead of print]


Expression of SIRT5 protein in gastric cancer cells.

Wu ZP, Fang HX.

J Biol Regul Homeost Agents. 2019 Nov-Dec;33(6):1675-1683. doi: 10.23812/19-184-A.


Antibacterial and antifungal activities of different polar extracts from Anoectochilus roxburghii.

Zhu J, Yang J, Fang H, Zhang A, Feng Y, Shao Q.

Pak J Pharm Sci. 2019 Nov;32(6):2745-2750.


Abl signaling directs growth of a pioneer axon in Drosophila by shaping the intrinsic fluctuations of actin.

Clarke A, McQueen PG, Fang HY, Kannan R, Wang V, McCreedy E, Wincovitch S, Giniger E.

Mol Biol Cell. 2020 Jan 22:mbcE19100564. doi: 10.1091/mbc.E19-10-0564. [Epub ahead of print]


Dynamic morphogenesis of a pioneer axon in Drosophila and its regulation by Abl tyrosine kinase.

Clarke A, McQueen PG, Fang HY, Kannan R, Wang V, McCreedy E, Buckley T, Johannessen EM, Wincovitch S, Giniger E.

Mol Biol Cell. 2020 Jan 22:mbcE19100563. doi: 10.1091/mbc.E19-10-0563. [Epub ahead of print]


Donor Brain Death Leads to a Worse Ischemia-Reperfusion Injury and Biliary Injury After Liver Transplantation in Rats.

Chen S, Fang H, Li J, Shi JH, Zhang J, Wen P, Wang Z, Cao S, Yang H, Pan J, Tang H, Zhang H, Guo W, Zhang S.

Transplant Proc. 2020 Jan - Feb;52(1):373-382. doi: 10.1016/j.transproceed.2019.10.012. Epub 2020 Jan 16.


RNF213 suppresses carcinogenesis in glioblastoma by affecting MAPK/JNK signaling pathway.

Wang X, Ye M, Wu M, Fang H, Xiao B, Xie L, Zhu X.

Clin Transl Oncol. 2020 Jan 17. doi: 10.1007/s12094-020-02286-x. [Epub ahead of print]


Treatment patterns and direct medical costs of metastatic colorectal cancer patients: a retrospective study of electronic medical records from urban China.

Shen L, Li Q, Wang W, Zhu L, Zhao Q, Nie Y, Zhu B, Ma D, Lin X, Cai X, Fang W, Peng C, Chen Y, Fang H, Yin Z, Li H, Wang N, Xu R.

J Med Econ. 2020 Feb 13:1-8. doi: 10.1080/13696998.2020.1717500. [Epub ahead of print]


[Acceptance and Related Causes of Clinical Trials among Cancer Patients in China].

Huang H, Fan Q, Fang H, Wu D, Wang S, Bai Y, Yu A, Wang H, Sun C, Yu Y, Fang Y, Yang S, Shi J, He R, Li N.

Zhongguo Fei Ai Za Zhi. 2020 Jan 20;23(1):41-49. doi: 10.3779/j.issn.1009-3419.2020.01.07. Chinese.


[Awareness and Influencing Factors of Clinical Trial Among Cancer Patients in China].

Huang H, Fang Y, Fang H, Wu D, Bai Y, Wang S, Yu A, Wang H, Sun C, Fan Q, Yu Y, Yang C, Shi J, He R, Li N.

Zhongguo Fei Ai Za Zhi. 2020 Jan 20;23(1):5-14. doi: 10.3779/j.issn.1009-3419.2020.01.02. Chinese.


Mutations in FASTKD2 are associated with mitochondrial disease with multi-OXPHOS deficiency.

Wei X, Du M, Li D, Wen S, Xie J, Li Y, Chen A, Zhang K, Xu P, Jia M, Wen C, Zhou H, Lyu J, Yang Y, Fang H.

Hum Mutat. 2020 Jan 16. doi: 10.1002/humu.23985. [Epub ahead of print]


Calixarene-Functionalized Porous Carbon Aerogels for Polysulfide Capture: Cathodes for High Performance Lithium-Sulfur Batteries.

Zhang X, Li X, Gao W, Ma L, Fang H, Shu Y, Ye J, Ding Y.

Chempluschem. 2019 Nov;84(11):1709-1715. doi: 10.1002/cplu.201900554.


Evolutionary selection of biofilm-mediated extended phenotypes in Yersinia pestis in response to a fluctuating environment.

Cui Y, Schmid BV, Cao H, Dai X, Du Z, Ryan Easterday W, Fang H, Guo C, Huang S, Liu W, Qi Z, Song Y, Tian H, Wang M, Wu Y, Xu B, Yang C, Yang J, Yang X, Zhang Q, Jakobsen KS, Zhang Y, Stenseth NC, Yang R.

Nat Commun. 2020 Jan 15;11(1):281. doi: 10.1038/s41467-019-14099-w.


Monocyte-to-High-Density Lipoprotein Ratio Predicts the Outcome of Acute Ischemic Stroke.

Liu H, Liu K, Pei L, Gao Y, Zhao L, Sun S, Wu J, Li Y, Fang H, Song B, Xu Y.

J Atheroscler Thromb. 2020 Jan 16. doi: 10.5551/jat.51151. [Epub ahead of print]


Photodeposition of Pd onto TiO2 nanowires for aqueous-phase selective hydrogenation of phenolics to cyclohexanones.

Tian C, Fang H, Chen H, Chen W, Zhou S, Duan X, Liu X, Yuan Y.

Nanoscale. 2020 Jan 28;12(4):2603-2612. doi: 10.1039/c9nr08324c. Epub 2020 Jan 15.


IMCs Microstructure Evolution Dependence of Mechanical Properties for Ni/Sn/Ni Micro Solder-Joints.

Ren N, Fang H, Wang D, Hou C, Zhao Y, Chen F, Tian Y, Paik KW, Wu Y.

Materials (Basel). 2020 Jan 6;13(1). pii: E252. doi: 10.3390/ma13010252.

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