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Items: 48


A Clinicopathologic and Molecular Analysis of Fumarate Hydratase-Deficient Renal Cell Carcinoma in 32 Patients.

Lau HD, Chan E, Fan AC, Kunder CA, Williamson SR, Zhou M, Idrees MT, Maclean FM, Gill AJ, Kao CS.

Am J Surg Pathol. 2019 Sep 12. doi: 10.1097/PAS.0000000000001372. [Epub ahead of print]


Multiregion Quantification of Extracellular Signal-regulated Kinase Activity in Renal Cell Carcinoma.

Hoerner CR, Massoudi R, Metzner TJ, Stell L, O'Rourke JJ, Kong CS, Liliental JE, Brooks JD, Sabatti C, Leppert JT, Fan AC.

Eur Urol Oncol. 2018 Nov 19. pii: S2588-9311(18)30171-8. doi: 10.1016/j.euo.2018.09.011. [Epub ahead of print]


Postmarketing Analysis of Sipuleucel-T-The Importance of Real-World Data.

Fan AC, Leppert JT.

JAMA Netw Open. 2019 Aug 2;2(8):e199233. doi: 10.1001/jamanetworkopen.2019.9233. No abstract available.


Time on Therapy for at Least Three Months Correlates with Overall Survival in Metastatic Renal Cell Carcinoma.

Chen VJ, Hernandez-Meza G, Agrawal P, Zhang CA, Xie L, Gong CL, Hoerner CR, Srinivas S, Oermann EK, Fan AC.

Cancers (Basel). 2019 Jul 17;11(7). pii: E1000. doi: 10.3390/cancers11071000.


Early Changes in CT Perfusion Parameters: Primary Renal Carcinoma Versus Metastases After Treatment with Targeted Therapy.

Fan AC, Sundaram V, Kino A, Schmiedeskamp H, Metzner TJ, Kamaya A.

Cancers (Basel). 2019 Apr 30;11(5). pii: E608. doi: 10.3390/cancers11050608.


The 'Achilles Heel' of Metabolism in Renal Cell Carcinoma: Glutaminase Inhibition as a Rational Treatment Strategy.

Hoerner CR, Chen VJ, Fan AC.

Kidney Cancer. 2019 Feb 5;3(1):15-29. doi: 10.3233/KCA-180043. Review.


18F-FPPRGD2 PET/CT in patients with metastatic renal cell cancer.

Toriihara A, Duan H, Thompson HM, Park S, Hatami N, Baratto L, Fan AC, Iagaru A.

Eur J Nucl Med Mol Imaging. 2019 Jul;46(7):1518-1523. doi: 10.1007/s00259-019-04295-7. Epub 2019 Mar 8.


Monitoring Neutropenia for Cancer Patients at the Point of Care.

Inan H, Kingsley JL, Ozen MO, Tekin HC, Hoerner CR, Imae Y, Metzner TJ, Preiss JS, Durmus NG, Ozsoz M, Wakelee H, Fan AC, Tüzel E, Demirci U.

Small Methods. 2017 Sep 11;1(9). pii: 1700193. doi: 10.1002/smtd.201700193. Epub 2017 Aug 9.


Corrigendum to "KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study" [Leuk. Res. 50 (Nov) (2016) 123-131. PubMed PMID: 27736729].

Swords RT, Greenberg PL, Wei AH, Durrant S, Advani AS, Hertzberg MS, Lewis ID, Rivera G, Gratzinger D, Fan AC, Felsher DW, Cortes JE, Watts JM, Yarranton GT, Walling JM, Lancet JE.

Leuk Res. 2017 Aug;59:65. doi: 10.1016/j.leukres.2017.02.007. Epub 2017 May 30. No abstract available.


High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.

Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC.

Sci Transl Med. 2017 Feb 15;9(377). pii: eaaf2584. doi: 10.1126/scitranslmed.aaf2584.


Microbubble gas volume: A unifying dose parameter in blood-brain barrier opening by focused ultrasound.

Song KH, Fan AC, Hinkle JJ, Newman J, Borden MA, Harvey BK.

Theranostics. 2017 Jan 1;7(1):144-152. doi: 10.7150/thno.15987. eCollection 2017.


KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study.

Swords RT, Greenberg PL, Wei AH, Durrant S, Advani AS, Hertzberg MS, Jonas BA, Lewis ID, Rivera G, Gratzinger D, Fan AC, Felsher DW, Cortes JE, Watts JM, Yarranton GT, Walling JM, Lancet JE.

Leuk Res. 2016 Nov;50:123-131. doi: 10.1016/j.leukres.2016.09.012. Epub 2016 Sep 28. Erratum in: Leuk Res. 2017 Aug;59:65.


RNA Granules and Diseases: A Case Study of Stress Granules in ALS and FTLD.

Fan AC, Leung AK.

Adv Exp Med Biol. 2016;907:263-96. doi: 10.1007/978-3-319-29073-7_11.


BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia.

Li Y, Deutzmann A, Choi PS, Fan AC, Felsher DW.

Oncotarget. 2016 May 10;7(19):26926-34. doi: 10.18632/oncotarget.8731.


High Efficiency Molecular Delivery with Sequential Low-Energy Sonoporation Bursts.

Song KH, Fan AC, Brlansky JT, Trudeau T, Gutierrez-Hartmann A, Calvisi ML, Borden MA.

Theranostics. 2015 Oct 18;5(12):1419-27. doi: 10.7150/thno.13033. eCollection 2015.


Oncogene withdrawal engages the immune system to induce sustained cancer regression.

Casey SC, Li Y, Fan AC, Felsher DW.

J Immunother Cancer. 2014 Jul 15;2:24. doi: 10.1186/2051-1426-2-24. eCollection 2014. Review.


Alteration of the lipid profile in lymphomas induced by MYC overexpression.

Eberlin LS, Gabay M, Fan AC, Gouw AM, Tibshirani RJ, Felsher DW, Zare RN.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10450-5. doi: 10.1073/pnas.1409778111. Epub 2014 Jul 3.


[Multi-spectroscopy applied to study on a late neolithic colored stone from Yuhui Site in Huaihe Basin].

Wang HG, Jin ZY, Xie Z, Fan AC, Yan LF, Zhu BQ, Wang JH.

Guang Pu Xue Yu Guang Pu Fen Xi. 2013 Sep;33(9):2305-10. Chinese.


BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells.

Beurlet S, Omidvar N, Gorombei P, Krief P, Le Pogam C, Setterblad N, de la Grange P, Leboeuf C, Janin A, Noguera ME, Hervatin F, Sarda-Mantel L, Konopleva M, Andreeff M, Tu AW, Fan AC, Felsher DW, Whetton A, Pla M, West R, Fenaux P, Chomienne C, Padua RA.

Blood. 2013 Oct 17;122(16):2864-76. doi: 10.1182/blood-2012-07-445635. Epub 2013 Aug 13.


Real-time nanoscale proteomic analysis of the novel multi-kinase pathway inhibitor rigosertib to measure the response to treatment of cancer.

Fan AC, O'Rourke JJ, Praharaj DR, Felsher DW.

Expert Opin Investig Drugs. 2013 Nov;22(11):1495-509. doi: 10.1517/13543784.2013.829453. Epub 2013 Aug 12. Review.


Associations among self-concept, verbal behaviors, and group climate early in the group counseling process.

Jen Der Pan P, Fan AC, Bhat CS, Chang SS.

Psychol Rep. 2012 Dec;111(3):739-54.


Verbal interactions in Taiwanese group counseling process: a cross-cultural perspective.

Pan PJ, Deng LY, Fan AC, Yuan JS.

Psychol Rep. 2012 Oct;111(2):349-63.


Cryptococcal osteomyelitis and meningitis in a patient with non-hodgkin's lymphoma treated with PEP-C.

To CA, Hsieh RW, McClellan JS, Howard W, Fischbein NJ, Brown JM, Felsher DW, Fan AC.

BMJ Case Rep. 2012 Sep 7;2012. pii: bcr0820114578. doi: 10.1136/bcr.08.2011.4578.


"Picolog," a synthetically-available bryostatin analog, inhibits growth of MYC-induced lymphoma in vivo.

DeChristopher BA, Fan AC, Felsher DW, Wender PA.

Oncotarget. 2012 Jan;3(1):58-66.


Treatment of higher risk myelodysplastic syndrome patients unresponsive to hypomethylating agents with ON 01910.Na.

Seetharam M, Fan AC, Tran M, Xu L, Renschler JP, Felsher DW, Sridhar K, Wilhelm F, Greenberg PL.

Leuk Res. 2012 Jan;36(1):98-103. doi: 10.1016/j.leukres.2011.08.022. Epub 2011 Sep 14.


Interaction between the human mitochondrial import receptors Tom20 and Tom70 in vitro suggests a chaperone displacement mechanism.

Fan AC, Kozlov G, Hoegl A, Marcellus RC, Wong MJ, Gehring K, Young JC.

J Biol Chem. 2011 Sep 16;286(37):32208-19. doi: 10.1074/jbc.M111.280446. Epub 2011 Jul 19.


CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation.

Rakhra K, Bachireddy P, Zabuawala T, Zeiser R, Xu L, Kopelman A, Fan AC, Yang Q, Braunstein L, Crosby E, Ryeom S, Felsher DW.

Cancer Cell. 2010 Nov 16;18(5):485-98. doi: 10.1016/j.ccr.2010.10.002. Epub 2010 Oct 28. Erratum in: Cancer Cell. 2010 Dec 14;18(6):696.


Function of cytosolic chaperones in Tom70-mediated mitochondrial import.

Fan AC, Young JC.

Protein Pept Lett. 2011 Feb;18(2):122-31. Review.


Definition of an enhanced immune cell therapy in mice that can target stem-like lymphoma cells.

Contag CH, Sikorski R, Negrin RS, Schmidt T, Fan AC, Bachireddy P, Felsher DW, Thorne SH.

Cancer Res. 2010 Dec 1;70(23):9837-45. doi: 10.1158/0008-5472.CAN-10-2650. Epub 2010 Oct 8.


Human mitochondrial import receptor Tom70 functions as a monomer.

Fan AC, Gava LM, Ramos CH, Young JC.

Biochem J. 2010 Aug 1;429(3):553-63. doi: 10.1042/BJ20091855.


Supramolecular stacking of doxorubicin on carbon nanotubes for in vivo cancer therapy.

Liu Z, Fan AC, Rakhra K, Sherlock S, Goodwin A, Chen X, Yang Q, Felsher DW, Dai H.

Angew Chem Int Ed Engl. 2009;48(41):7668-72. doi: 10.1002/anie.200902612. No abstract available.


Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens.

Fan AC, Deb-Basu D, Orban MW, Gotlib JR, Natkunam Y, O'Neill R, Padua RA, Xu L, Taketa D, Shirer AE, Beer S, Yee AX, Voehringer DW, Felsher DW.

Nat Med. 2009 May;15(5):566-71. doi: 10.1038/nm.1903. Epub 2009 Apr 12.


Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds.

Kampa KM, Acoba JD, Chen D, Gay J, Lee H, Beemer K, Padiernos E, Boonmark N, Zhu Z, Fan AC, Bailey AS, Fleming WH, Corless C, Felsher DW, Naumovski L, Lopez CD.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4390-5. doi: 10.1073/pnas.0809080106. Epub 2009 Feb 26.


A quantitative PCR method to detect blood microRNAs associated with tumorigenesis in transgenic mice.

Fan AC, Goldrick MM, Ho J, Liang Y, Bachireddy P, Felsher DW.

Mol Cancer. 2008 Sep 30;7:74. doi: 10.1186/1476-4598-7-74.


Combined Inactivation of MYC and K-Ras oncogenes reverses tumorigenesis in lung adenocarcinomas and lymphomas.

Tran PT, Fan AC, Bendapudi PK, Koh S, Komatsubara K, Chen J, Horng G, Bellovin DI, Giuriato S, Wang CS, Whitsett JA, Felsher DW.

PLoS One. 2008 May 7;3(5):e2125. doi: 10.1371/journal.pone.0002125.


MCMC curve sampling for image segmentation.

Fan AC, Fisher JW 3rd, Wells WM 3rd, Levitt JJ, Willsky AS.

Med Image Comput Comput Assist Interv. 2007;10(Pt 2):477-85.


Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation.

Wu CH, van Riggelen J, Yetil A, Fan AC, Bachireddy P, Felsher DW.

Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13028-33. Epub 2007 Jul 30.


Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis.

Shachaf CM, Perez OD, Youssef S, Fan AC, Elchuri S, Goldstein MJ, Shirer AE, Sharpe O, Chen J, Mitchell DJ, Chang M, Nolan GP, Steinman L, Felsher DW.

Blood. 2007 Oct 1;110(7):2674-84. Epub 2007 Jul 10.


Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import.

Bhangoo MK, Tzankov S, Fan AC, Dejgaard K, Thomas DY, Young JC.

Mol Biol Cell. 2007 Sep;18(9):3414-28. Epub 2007 Jun 27.


Silent celiac disease activated by pancreaticoduodenectomy.

Maple JT, Pearson RK, Murray JA, Kelly DG, Lara LF, Fan AC.

Dig Dis Sci. 2007 Sep;52(9):2140-4. Epub 2007 Mar 21.


Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch.

Giuriato S, Ryeom S, Fan AC, Bachireddy P, Lynch RC, Rioth MJ, van Riggelen J, Kopelman AM, Passegué E, Tang F, Folkman J, Felsher DW.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16266-71. Epub 2006 Oct 20.


Hsp90 functions in the targeting and outer membrane translocation steps of Tom70-mediated mitochondrial import.

Fan AC, Bhangoo MK, Young JC.

J Biol Chem. 2006 Nov 3;281(44):33313-24. Epub 2006 Sep 12.


Conditional animal models: a strategy to define when oncogenes will be effective targets to treat cancer.

Giuriato S, Rabin K, Fan AC, Shachaf CM, Felsher DW.

Semin Cancer Biol. 2004 Feb;14(1):3-11. Review.


Comparison of direct percutaneous endoscopic jejunostomy and PEG with jejunal extension.

Fan AC, Baron TH, Rumalla A, Harewood GC.

Gastrointest Endosc. 2002 Dec;56(6):890-4.


p53 mutations do not predict response to paclitaxel in metastatic nonsmall cell lung carcinoma.

King TC, Akerley W, Fan AC, Moore T, Mangray S, Hsiu Chen M, Safran H.

Cancer. 2000 Aug 15;89(4):769-73.


Are Women Underrepresented as Authors and Editors of Educational Psychology Journals?

Robinson DH, McKay DW, Katayama AD, Fan AC.

Contemp Educ Psychol. 1998 Jul;23(3):331-43.


Estimation of the extent of drug-excipient interactions involving croscarmellose sodium.

Hollenbeck RG, Mitrevej KT, Fan AC.

J Pharm Sci. 1983 Mar;72(3):325-7. No abstract available.


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