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Items: 1 to 50 of 159

1.

Translocation of a Cell Surface Spliceosomal Complex Induces Alternative Splicing Events and Lymphoma Cell Necrosis.

Tonapi SS, Pannu V, Duncan JE, Rosenow M, Helmstetter A, Magee D, Zhang Q, Tinder TT, Richards M, Halbert DD, Famulok M, Spetzler D, Miglarese MR, O'Neill HA, Mayer G.

Cell Chem Biol. 2019 May 16;26(5):756-764.e6. doi: 10.1016/j.chembiol.2019.02.016. Epub 2019 Mar 28.

PMID:
30930163
2.

Orthogonally Photocontrolled Non-Autonomous DNA Walker.

Škugor M, Valero J, Murayama K, Centola M, Asanuma H, Famulok M.

Angew Chem Int Ed Engl. 2019 May 20;58(21):6948-6951. doi: 10.1002/anie.201901272. Epub 2019 Apr 12.

PMID:
30897257
3.

Temporal and Reversible Control of a DNAzyme by Orthogonal Photoswitching.

Haydell MW, Centola M, Adam V, Valero J, Famulok M.

J Am Chem Soc. 2018 Dec 12;140(49):16868-16872. doi: 10.1021/jacs.8b08738. Epub 2018 Nov 26.

PMID:
30444607
4.

High-Yield Spin Labeling of Long RNAs for Electron Paramagnetic Resonance Spectroscopy.

Kerzhner M, Matsuoka H, Wuebben C, Famulok M, Schiemann O.

Biochemistry. 2018 May 22;57(20):2923-2931. doi: 10.1021/acs.biochem.8b00040. Epub 2018 May 10.

PMID:
29715006
5.

A bio-hybrid DNA rotor-stator nanoengine that moves along predefined tracks.

Valero J, Pal N, Dhakal S, Walter NG, Famulok M.

Nat Nanotechnol. 2018 Jun;13(6):496-503. doi: 10.1038/s41565-018-0109-z. Epub 2018 Apr 9.

6.

Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes.

Domenyuk V, Gatalica Z, Santhanam R, Wei X, Stark A, Kennedy P, Toussaint B, Levenberg S, Wang J, Xiao N, Greil R, Rinnerthaler G, Gampenrieder SP, Heimberger AB, Berry DA, Barker A, Quackenbush J, Marshall JL, Poste G, Vacirca JL, Vidal GA, Schwartzberg LS, Halbert DD, Voss A, Magee D, Miglarese MR, Famulok M, Mayer G, Spetzler D.

Nat Commun. 2018 Mar 23;9(1):1219. doi: 10.1038/s41467-018-03631-z.

7.

Supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells.

Prusty DK, Adam V, Zadegan RM, Irsen S, Famulok M.

Nat Commun. 2018 Feb 7;9(1):535. doi: 10.1038/s41467-018-02929-2.

8.

Expanding the Toolbox of Photoswitches for DNA Nanotechnology Using Arylazopyrazoles.

Adam V, Prusty DK, Centola M, Škugor M, Hannam JS, Valero J, Klöckner B, Famulok M.

Chemistry. 2018 Jan 24;24(5):1062-1066. doi: 10.1002/chem.201705500. Epub 2018 Jan 2.

PMID:
29168907
9.

Allosteric Control of Oxidative Catalysis by a DNA Rotaxane Nanostructure.

Centola M, Valero J, Famulok M.

J Am Chem Soc. 2017 Nov 15;139(45):16044-16047. doi: 10.1021/jacs.7b08839. Epub 2017 Nov 1.

PMID:
29058418
10.

Studying the Conformation of a Receptor Tyrosine Kinase in Solution by Inhibitor-Based Spin Labeling.

Yin DM, Hannam JS, Schmitz A, Schiemann O, Hagelueken G, Famulok M.

Angew Chem Int Ed Engl. 2017 Jul 10;56(29):8417-8421. doi: 10.1002/anie.201703154. Epub 2017 Jun 19.

11.

Interlocked DNA topologies for nanotechnology.

Valero J, Lohmann F, Famulok M.

Curr Opin Biotechnol. 2017 Dec;48:159-167. doi: 10.1016/j.copbio.2017.04.002. Epub 2017 May 12. Review.

PMID:
28505598
12.

Plasma Exosome Profiling of Cancer Patients by a Next Generation Systems Biology Approach.

Domenyuk V, Zhong Z, Stark A, Xiao N, O'Neill HA, Wei X, Wang J, Tinder TT, Tonapi S, Duncan J, Hornung T, Hunter A, Miglarese MR, Schorr J, Halbert DD, Quackenbush J, Poste G, Berry DA, Mayer G, Famulok M, Spetzler D.

Sci Rep. 2017 Feb 20;7:42741. doi: 10.1038/srep42741.

13.

Post-synthetic Spin-Labeling of RNA through Click Chemistry for PELDOR Measurements.

Kerzhner M, Abdullin D, Więcek J, Matsuoka H, Hagelueken G, Schiemann O, Famulok M.

Chemistry. 2016 Aug 16;22(34):12113-21. doi: 10.1002/chem.201601897. Epub 2016 Jul 14.

PMID:
27412453
14.

Retraction Notice to: Cytohesins Are Cytoplasmic ErbB Receptor Activators.

Bill A, Schmitz A, Albertoni B, Song JN, Heukamp LC, Walrafen D, Thorwirth F, Verveer PJ, Zimmer S, Meffert L, Schreiber A, Chatterjee S, Thomas RK, Ullrich RT, Lang T, Famulok M.

Cell. 2016 May 19;165(5):1293. doi: 10.1016/j.cell.2016.05.013. No abstract available.

15.

Daisy Chain Rotaxanes Made from Interlocked DNA Nanostructures.

Weigandt J, Chung CL, Jester SS, Famulok M.

Angew Chem Int Ed Engl. 2016 Apr 25;55(18):5512-6. doi: 10.1002/anie.201601042. Epub 2016 Mar 24.

16.

Single-Stranded Tile Stoppers for Interlocked DNA Architectures.

Valero J, Lohmann F, Keppner D, Famulok M.

Chembiochem. 2016 Jun 16;17(12):1146-9. doi: 10.1002/cbic.201500685. Epub 2016 Apr 5.

PMID:
26972112
17.

Switchable Reconfiguration of a Seven-Ring Interlocked DNA Catenane Nanostructure.

Lu CH, Cecconello A, Qi XJ, Wu N, Jester SS, Famulok M, Matthies M, Schmidt TL, Willner I.

Nano Lett. 2015 Oct 14;15(10):7133-7. doi: 10.1021/acs.nanolett.5b03280. Epub 2015 Sep 21.

PMID:
26360345
18.

Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease.

Zhai J, Zhang L, Mojsilovic-Petrovic J, Jian X, Thomas J, Homma K, Schmitz A, Famulok M, Ichijo H, Argon Y, Randazzo PA, Kalb RG.

J Neurosci. 2015 Jun 17;35(24):9088-105. doi: 10.1523/JNEUROSCI.5032-13.2015.

19.

In vitro activity of wALADin benzimidazoles against different life cycle stages of Plasmodium parasites.

Lentz CS, Sattler JM, Fendler M, Gottwalt S, Halls VS, Strassel S, Arriens S, Hannam JS, Specht S, Famulok M, Mueller AK, Hoerauf A, Pfarr KM.

Antimicrob Agents Chemother. 2015 Jan;59(1):654-8. doi: 10.1128/AAC.02383-14. Epub 2014 Oct 13.

20.

Aptamers and SELEX in Chemistry & Biology.

Famulok M, Mayer G.

Chem Biol. 2014 Sep 18;21(9):1055-8. doi: 10.1016/j.chembiol.2014.08.003.

21.

Interlocked DNA nanostructures controlled by a reversible logic circuit.

Li T, Lohmann F, Famulok M.

Nat Commun. 2014 Sep 17;5:4940. doi: 10.1038/ncomms5940.

22.

Logic gating by macrocycle displacement using a double-stranded DNA [3]rotaxane shuttle.

Lohmann F, Weigandt J, Valero J, Famulok M.

Angew Chem Int Ed Engl. 2014 Sep 22;53(39):10372-6. doi: 10.1002/anie.201405447. Epub 2014 Jul 30.

PMID:
25078433
23.

Switchable reconfiguration of an interlocked DNA olympiadane nanostructure.

Lu CH, Qi XJ, Cecconello A, Jester SS, Famulok M, Willner I.

Angew Chem Int Ed Engl. 2014 Jul 14;53(29):7499-503. doi: 10.1002/anie.201403202. Epub 2014 May 30.

PMID:
24889855
24.

A novel family of structurally stable double stranded DNA catenanes.

Lohmann F, Valero J, Famulok M.

Chem Commun (Camb). 2014 Jun 11;50(46):6091-3. doi: 10.1039/c4cc02030h.

PMID:
24777123
25.

Mechanically interlocked DNA nanostructures for functional devices.

Jester SS, Famulok M.

Acc Chem Res. 2014 Jun 17;47(6):1700-9. doi: 10.1021/ar400321h. Epub 2014 Mar 14.

PMID:
24627986
26.

wALADin benzimidazoles differentially modulate the function of porphobilinogen synthase orthologs.

Lentz CS, Halls VS, Hannam JS, Strassel S, Lawrence SH, Jaffe EK, Famulok M, Hoerauf A, Pfarr KM.

J Med Chem. 2014 Mar 27;57(6):2498-510. doi: 10.1021/jm401785n. Epub 2014 Feb 25.

27.

New chemotypes for wALADin1-like inhibitors of delta-aminolevulinic acid dehydratase from Wolbachia endobacteria.

Lentz CS, Stumpfe D, Bajorath J, Famulok M, Hoerauf A, Pfarr KM.

Bioorg Med Chem Lett. 2013 Oct 15;23(20):5558-62. doi: 10.1016/j.bmcl.2013.08.052. Epub 2013 Aug 20.

PMID:
24012123
28.

Cyplecksins are covalent inhibitors of the pleckstrin homology domain of cytohesin.

Hussein M, Bettio M, Schmitz A, Hannam JS, Theis J, Mayer G, Dosa S, Gütschow M, Famulok M.

Angew Chem Int Ed Engl. 2013 Sep 2;52(36):9529-33. doi: 10.1002/anie.201302207. Epub 2013 Jul 10. No abstract available.

PMID:
23843286
29.

RNA-aptamers that modulate the RhoGEF activity of Tiam1.

Niebel B, Wosnitza CI, Famulok M.

Bioorg Med Chem. 2013 Oct 15;21(20):6239-46. doi: 10.1016/j.bmc.2013.05.021. Epub 2013 May 23.

PMID:
23757206
30.

Pseudo-complementary PNA actuators as reversible switches in dynamic DNA nanotechnology.

Ackermann D, Famulok M.

Nucleic Acids Res. 2013 Apr;41(8):4729-39. doi: 10.1093/nar/gkt121. Epub 2013 Feb 26.

31.

A selective inhibitor of heme biosynthesis in endosymbiotic bacteria elicits antifilarial activity in vitro.

Lentz CS, Halls V, Hannam JS, Niebel B, Strübing U, Mayer G, Hoerauf A, Famulok M, Pfarr KM.

Chem Biol. 2013 Feb 21;20(2):177-87. doi: 10.1016/j.chembiol.2012.11.009.

32.

I-motif-programmed functionalization of DNA nanocircles.

Li T, Famulok M.

J Am Chem Soc. 2013 Jan 30;135(4):1593-9. doi: 10.1021/ja3118224. Epub 2013 Jan 22.

PMID:
23312021
33.

Aptamer-based affinity labeling of proteins.

Vinkenborg JL, Mayer G, Famulok M.

Angew Chem Int Ed Engl. 2012 Sep 3;51(36):9176-80. doi: 10.1002/anie.201204174. Epub 2012 Aug 2.

PMID:
22865679
34.

Anti-proliferative effect of cytohesin inhibition in gefitinib-resistant lung cancer cells.

Bill A, Schmitz A, König K, Heukamp LC, Hannam JS, Famulok M.

PLoS One. 2012;7(7):e41179. doi: 10.1371/journal.pone.0041179. Epub 2012 Jul 18.

35.

Reversible light switch for macrocycle mobility in a DNA rotaxane.

Lohmann F, Ackermann D, Famulok M.

J Am Chem Soc. 2012 Jul 25;134(29):11884-7. doi: 10.1021/ja3042096. Epub 2012 Jul 16.

36.

Pan-selective aptamers for the family of small GTPases.

Hons M, Niebel B, Karnowski N, Weiche B, Famulok M.

Chembiochem. 2012 Jul 9;13(10):1433-7. doi: 10.1002/cbic.201200164. Epub 2012 Jun 11. No abstract available.

PMID:
22689339
37.

Design strategy for DNA rotaxanes with a mechanically reinforced PX100 axle.

Ackermann D, Jester SS, Famulok M.

Angew Chem Int Ed Engl. 2012 Jul 2;51(27):6771-5. doi: 10.1002/anie.201202816. Epub 2012 May 31. No abstract available.

PMID:
22653874
38.

Grp1 plays a key role in linking insulin signaling to glut4 recycling.

Li J, Malaby AW, Famulok M, Sabe H, Lambright DG, Hsu VW.

Dev Cell. 2012 Jun 12;22(6):1286-98. doi: 10.1016/j.devcel.2012.03.004. Epub 2012 May 17.

39.

Input-dependent induction of oligonucleotide structural motifs for performing molecular logic.

Li T, Ackermann D, Hall AM, Famulok M.

J Am Chem Soc. 2012 Feb 22;134(7):3508-16. doi: 10.1021/ja2108883. Epub 2012 Feb 8.

40.

Label-free impedimetric aptasensor for lysozyme detection based on carbon nanotube-modified screen-printed electrodes.

Rohrbach F, Karadeniz H, Erdem A, Famulok M, Mayer G.

Anal Biochem. 2012 Feb 15;421(2):454-9. doi: 10.1016/j.ab.2011.11.034. Epub 2011 Dec 2.

PMID:
22200651
41.

Inhibition of cell migration by PITENINs: the role of ARF6.

Miao B, Skidan I, Yang J, You Z, Fu X, Famulok M, Schaffhausen B, Torchilin V, Yuan J, Degterev A.

Oncogene. 2012 Sep 27;31(39):4317-32. doi: 10.1038/onc.2011.593. Epub 2011 Dec 19.

42.

A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe.

Albertoni B, Hannam JS, Ackermann D, Schmitz A, Famulok M.

Chem Commun (Camb). 2012 Jan 30;48(9):1272-4. doi: 10.1039/c2cc16477a. Epub 2011 Dec 16.

PMID:
22179571
43.

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation.

Beyer M, Thabet Y, Müller RU, Sadlon T, Classen S, Lahl K, Basu S, Zhou X, Bailey-Bucktrout SL, Krebs W, Schönfeld EA, Böttcher J, Golovina T, Mayer CT, Hofmann A, Sommer D, Debey-Pascher S, Endl E, Limmer A, Hippen KL, Blazar BR, Balderas R, Quast T, Waha A, Mayer G, Famulok M, Knolle PA, Wickenhauser C, Kolanus W, Schermer B, Bluestone JA, Barry SC, Sparwasser T, Riley JL, Schultze JL.

Nat Immunol. 2011 Aug 14;12(9):898-907. doi: 10.1038/ni.2084.

44.

Aptamer modules as sensors and detectors.

Famulok M, Mayer G.

Acc Chem Res. 2011 Dec 20;44(12):1349-58. doi: 10.1021/ar2000293. Epub 2011 Aug 5.

PMID:
21819040
45.

Aptamers for allosteric regulation.

Vinkenborg JL, Karnowski N, Famulok M.

Nat Chem Biol. 2011 Jul 18;7(8):519-27. doi: 10.1038/nchembio.609. Review.

PMID:
21769099
46.

A luminescent oxygen channeling biosensor that measures small GTPase activation.

Niebel B, Weiche B, Mueller AL, Li DY, Karnowski N, Famulok M.

Chem Commun (Camb). 2011 Jul 14;47(26):7521-3. doi: 10.1039/c1cc11944c. Epub 2011 May 31.

47.

Gernot Boche (1938-2011).

Hoffmann RW, Famulok M.

Angew Chem Int Ed Engl. 2011 May 27;50(23):5251-2. doi: 10.1002/anie.201102565. Epub 2011 May 3. No abstract available.

PMID:
21542085
48.

A homogeneous fluorescence resonance energy transfer system for monitoring the activation of a protein switch in real time.

Bill A, Blockus H, Stumpfe D, Bajorath J, Schmitz A, Famulok M.

J Am Chem Soc. 2011 Jun 1;133(21):8372-9. doi: 10.1021/ja202513s. Epub 2011 May 4.

PMID:
21517092
49.

Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures.

Mayer G, Ahmed MS, Dolf A, Endl E, Knolle PA, Famulok M.

Nat Protoc. 2010 Dec;5(12):1993-2004. doi: 10.1038/nprot.2010.163. Epub 2010 Dec 2.

PMID:
21127492
50.

Cytohesins are cytoplasmic ErbB receptor activators.

Bill A, Schmitz A, Albertoni B, Song JN, Heukamp LC, Walrafen D, Thorwirth F, Verveer PJ, Zimmer S, Meffert L, Schreiber A, Chatterjee S, Thomas RK, Ullrich RT, Lang T, Famulok M.

Cell. 2010 Oct 15;143(2):201-11. doi: 10.1016/j.cell.2010.09.011. Retraction in: Cell. 2016 May 19;165(5):1293.

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