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Items: 1 to 50 of 71

1.

EGFP insertional mutagenesis reveals multiple FXR2P fibrillar states with differing ribosome association in neurons.

Stackpole EE, Akins MR, Ivshina M, Murthy AC, Fawzi NL, Fallon JR.

Biol Open. 2019 Aug 21;8(8). pii: bio046383. doi: 10.1242/bio.046383.

2.

Meta-analysis of Genetic Modifiers Reveals Candidate Dysregulated Pathways in Amyotrophic Lateral Sclerosis.

Yanagi KS, Wu Z, Amaya J, Chapkis N, Duffy AM, Hajdarovic KH, Held A, Mathur AD, Russo K, Ryan VH, Steinert BL, Whitt JP, Fallon JR, Fawzi NL, Lipscombe D, Reenan RA, Wharton KA, Hart AC.

Neuroscience. 2019 Jan 1;396:A3-A20. doi: 10.1016/j.neuroscience.2018.10.033.

PMID:
30594291
3.

Publisher Correction: TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.

White MA, Kim E, Duffy A, Adalbert R, Phillips BU, Peters OM, Stephenson J, Yang S, Massenzio F, Lin Z, Andrews S, Segonds-Pichon A, Metterville J, Saksida LM, Mead R, Ribchester RR, Barhomi Y, Serre T, Coleman MP, Fallon JR, Bussey TJ, Brown RH Jr, Sreedharan J.

Nat Neurosci. 2018 Aug;21(8):1138. doi: 10.1038/s41593-018-0160-y.

PMID:
29872124
4.

TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.

White MA, Kim E, Duffy A, Adalbert R, Phillips BU, Peters OM, Stephenson J, Yang S, Massenzio F, Lin Z, Andrews S, Segonds-Pichon A, Metterville J, Saksida LM, Mead R, Ribchester RR, Barhomi Y, Serre T, Coleman MP, Fallon JR, Bussey TJ, Brown RH Jr, Sreedharan J.

Nat Neurosci. 2018 Apr;21(4):552-563. doi: 10.1038/s41593-018-0113-5. Epub 2018 Mar 19. Erratum in: Nat Neurosci. 2018 Aug;21(8):1138.

5.

Non-Glycanated Biglycan and LTBP4: Leveraging the extracellular matrix for Duchenne Muscular Dystrophy therapeutics.

Fallon JR, McNally EM.

Matrix Biol. 2018 Aug;68-69:616-627. doi: 10.1016/j.matbio.2018.02.016. Epub 2018 Feb 23. Review.

6.

Fragile X granules are a family of axonal ribonucleoprotein particles with circuit-dependent protein composition and mRNA cargos.

Chyung E, LeBlanc HF, Fallon JR, Akins MR.

J Comp Neurol. 2018 Jan 1;526(1):96-108. doi: 10.1002/cne.24321. Epub 2017 Sep 20.

7.

Axonal ribosomes and mRNAs associate with fragile X granules in adult rodent and human brains.

Akins MR, Berk-Rauch HE, Kwan KY, Mitchell ME, Shepard KA, Korsak LI, Stackpole EE, Warner-Schmidt JL, Sestan N, Cameron HA, Fallon JR.

Hum Mol Genet. 2017 Jan 1;26(1):192-209. doi: 10.1093/hmg/ddw381.

8.

MuSK is a BMP co-receptor that shapes BMP responses and calcium signaling in muscle cells.

Yilmaz A, Kattamuri C, Ozdeslik RN, Schmiedel C, Mentzer S, Schorl C, Oancea E, Thompson TB, Fallon JR.

Sci Signal. 2016 Sep 6;9(444):ra87. doi: 10.1126/scisignal.aaf0890.

9.

How a patient advocacy group developed the first proposed draft guidance document for industry for submission to the U.S. Food and Drug Administration.

Furlong P, Bridges JF, Charnas L, Fallon JR, Fischer R, Flanigan KM, Franson TR, Gulati N, McDonald C, Peay H, Sweeney HL.

Orphanet J Rare Dis. 2015 Jun 24;10:82. doi: 10.1186/s13023-015-0281-2.

10.

Fragile X mental retardation protein regulates olfactory sensitivity but not odorant discrimination.

Schilit Nitenson A, Stackpole EE, Truszkowski TL, Midroit M, Fallon JR, Bath KG.

Chem Senses. 2015 Jun;40(5):345-50. doi: 10.1093/chemse/bjv019. Epub 2015 Apr 27.

11.

N-myristoylation regulates the axonal distribution of the Fragile X-related protein FXR2P.

Stackpole EE, Akins MR, Fallon JR.

Mol Cell Neurosci. 2014 Sep;62:42-50. doi: 10.1016/j.mcn.2014.08.003. Epub 2014 Aug 7.

12.

Biglycan: a promising new therapeutic for neuromuscular and musculoskeletal diseases.

Young MF, Fallon JR.

Curr Opin Genet Dev. 2012 Aug;22(4):398-400. doi: 10.1016/j.gde.2012.07.008. Epub 2012 Jul 27. No abstract available.

13.

Systematic mapping of fragile X granules in the mouse brain reveals a potential role for presynaptic FMRP in sensorimotor functions.

Akins MR, Leblanc HF, Stackpole EE, Chyung E, Fallon JR.

J Comp Neurol. 2012 Nov 1;520(16):3687-706. doi: 10.1002/cne.23123.

14.

Biglycan is an extracellular MuSK binding protein important for synapse stability.

Amenta AR, Creely HE, Mercado ML, Hagiwara H, McKechnie BA, Lechner BE, Rossi SG, Wang Q, Owens RT, Marrero E, Mei L, Hoch W, Young MF, McQuillan DJ, Rotundo RL, Fallon JR.

J Neurosci. 2012 Feb 15;32(7):2324-34. doi: 10.1523/JNEUROSCI.4610-11.2012.

15.

Calcium channels put synapses in their place.

Fallon JR.

Nat Neurosci. 2011 May;14(5):536-8. doi: 10.1038/nn.2822. No abstract available.

PMID:
21522142
16.

Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice.

Amenta AR, Yilmaz A, Bogdanovich S, McKechnie BA, Abedi M, Khurana TS, Fallon JR.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):762-7. doi: 10.1073/pnas.1013067108. Epub 2010 Dec 27.

17.

Presynaptic translation: stepping out of the postsynaptic shadow.

Akins MR, Berk-Rauch HE, Fallon JR.

Front Neural Circuits. 2009 Nov 4;3:17. doi: 10.3389/neuro.04.017.2009. eCollection 2009.

18.

The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits.

Christie SB, Akins MR, Schwob JE, Fallon JR.

J Neurosci. 2009 Feb 4;29(5):1514-24. doi: 10.1523/JNEUROSCI.3937-08.2009.

19.

Exclusion of biglycan mutations in a cohort of patients with neuromuscular disorders.

Peat RA, Gécz J, Fallon JR, Tarpey PS, Smith R, Futreal A, Stratton MR, Lamandé SR, Yang N, North KN.

Neuromuscul Disord. 2008 Aug;18(8):606-9. doi: 10.1016/j.nmd.2008.05.013. Epub 2008 Jul 7.

20.

Synapses go nucle(ol)ar.

Richter JD, Fallon JR.

Nat Neurosci. 2007 Apr;10(4):399-400. No abstract available.

PMID:
17387325
21.

Biglycan binds to alpha- and gamma-sarcoglycan and regulates their expression during development.

Rafii MS, Hagiwara H, Mercado ML, Seo NS, Xu T, Dugan T, Owens RT, Hook M, McQuillan DJ, Young MF, Fallon JR.

J Cell Physiol. 2006 Nov;209(2):439-47.

22.

Developmental regulation of biglycan expression in muscle and tendon.

Lechner BE, Lim JH, Mercado ML, Fallon JR.

Muscle Nerve. 2006 Sep;34(3):347-55.

PMID:
16810681
23.

Biglycan regulates the expression and sarcolemmal localization of dystrobrevin, syntrophin, and nNOS.

Mercado ML, Amenta AR, Hagiwara H, Rafii MS, Lechner BE, Owens RT, McQuillan DJ, Froehner SC, Fallon JR.

FASEB J. 2006 Aug;20(10):1724-6. Epub 2006 Jun 28.

24.

Dendrites contain a spacing pattern.

Taylor AB, Fallon JR.

J Neurosci. 2006 Jan 25;26(4):1154-63.

25.

Developmental expression of Xenopus fragile X mental retardation-1 gene.

Lim JH, Luo T, Sargent TD, Fallon JR.

Int J Dev Biol. 2005;49(8):981-4.

26.

AP-2alpha selectively regulates fragile X mental retardation-1 gene transcription during embryonic development.

Lim JH, Booker AB, Luo T, Williams T, Furuta Y, Lagutin O, Oliver G, Sargent TD, Fallon JR.

Hum Mol Genet. 2005 Jul 15;14(14):2027-34. Epub 2005 Jun 1.

PMID:
15930016
27.

Regulating fragile X gene transcription in the brain and beyond.

Lim JH, Booker AB, Fallon JR.

J Cell Physiol. 2005 Nov;205(2):170-5. Review.

PMID:
15895397
28.

Visual experience regulates transient expression and dendritic localization of fragile X mental retardation protein.

Gabel LA, Won S, Kawai H, McKinney M, Tartakoff AM, Fallon JR.

J Neurosci. 2004 Nov 24;24(47):10579-83. Erratum in: J Neurosci.2004 Dec 15;24(50):3 p following 11415.

29.
30.

Calcium-dependent maintenance of agrin-induced postsynaptic specializations.

Megeath LJ, Kirber MT, Hopf C, Hoch W, Fallon JR.

Neuroscience. 2003;122(3):659-68.

PMID:
14622909
31.

A role for the cytoplasmic polyadenylation element in NMDA receptor-regulated mRNA translation in neurons.

Wells DG, Dong X, Quinlan EM, Huang YS, Bear MF, Richter JD, Fallon JR.

J Neurosci. 2001 Dec 15;21(24):9541-8.

32.

Internalization of ionotropic glutamate receptors in response to mGluR activation.

Snyder EM, Philpot BD, Huber KM, Dong X, Fallon JR, Bear MF.

Nat Neurosci. 2001 Nov;4(11):1079-85.

PMID:
11687813
33.

Shaping membrane architecture: agrins in and out of the synapse.

Hagiwara H, Fallon JR.

J Cell Biol. 2001 Jun 25;153(7):F39-42. No abstract available.

34.

In search of molecular memory: experience-driven protein synthesis.

Wells DG, Fallon JR.

Cell Mol Life Sci. 2000 Sep;57(10):1335-9. Review. No abstract available.

PMID:
11078012
35.

Dendritic mRNA translation: deciphering the uncoded.

Wells DG, Fallon JR.

Nat Neurosci. 2000 Nov;3(11):1062-4. No abstract available.

PMID:
11036255
36.

Agrin and microvascular damage in Alzheimer's disease.

Berzin TM, Zipser BD, Rafii MS, Kuo-Leblanc V, Yancopoulos GD, Glass DJ, Fallon JR, Stopa EG.

Neurobiol Aging. 2000 Mar-Apr;21(2):349-55.

PMID:
10867220
37.
38.

Molecular mechanisms for activity-regulated protein synthesis in the synapto-dendritic compartment.

Wells DG, Richter JD, Fallon JR.

Curr Opin Neurobiol. 2000 Feb;10(1):132-7. Review.

PMID:
10679431
39.
40.
41.

Agrin in Alzheimer's disease: altered solubility and abnormal distribution within microvasculature and brain parenchyma.

Donahue JE, Berzin TM, Rafii MS, Glass DJ, Yancopoulos GD, Fallon JR, Stopa EG.

Proc Natl Acad Sci U S A. 1999 May 25;96(11):6468-72.

42.

Neurotrophins regulate agrin-induced postsynaptic differentiation.

Wells DG, McKechnie BA, Kelkar S, Fallon JR.

Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):1112-7.

43.

What maintains memories?

Lisman JE, Fallon JR.

Science. 1999 Jan 15;283(5400):339-40. No abstract available.

PMID:
9925495
44.

CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses.

Wu L, Wells D, Tay J, Mendis D, Abbott MA, Barnitt A, Quinlan E, Heynen A, Fallon JR, Richter JD.

Neuron. 1998 Nov;21(5):1129-39.

45.

SAP90 binds and clusters kainate receptors causing incomplete desensitization.

Garcia EP, Mehta S, Blair LA, Wells DG, Shang J, Fukushima T, Fallon JR, Garner CC, Marshall J.

Neuron. 1998 Oct;21(4):727-39.

46.

The role of alternative splicing in regulating agrin binding to muscle cells.

Deyst KA, McKechnie BA, Fallon JR.

Brain Res Dev Brain Res. 1998 Oct 1;110(2):185-91.

PMID:
9748567
47.
48.

Intracellular calcium regulates agrin-induced acetylcholine receptor clustering.

Megeath LJ, Fallon JR.

J Neurosci. 1998 Jan 15;18(2):672-8.

49.

The state of the union. Neuromuscular junction.

Wells DG, Fallon JR.

Curr Biol. 1996 Sep 1;6(9):1073-5. Review.

50.

Alternative splicing of agrin regulates its binding to heparin alpha-dystroglycan, and the cell surface.

O'Toole JJ, Deyst KA, Bowe MA, Nastuk MA, McKechnie BA, Fallon JR.

Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7369-74.

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