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Items: 1 to 50 of 167

1.

Cytochrome bcc-aa3 Oxidase Supercomplexes in the Aerobic Respiratory Chain of Streptomyces coelicolor A3(2).

Falke D, Fischer M, Biefel B, Ihling C, Hammerschmidt C, Reinefeld K, Haase A, Sinz A, Sawers RG.

J Mol Microbiol Biotechnol. 2019 Mar 12;28(6):255-268. doi: 10.1159/000496390. [Epub ahead of print]

PMID:
30861513
2.

Activity of Spore-Specific Respiratory Nitrate Reductase 1 of Streptomyces coelicolor A3(2) Requires a Functional Cytochrome bcc-aa 3 Oxidase Supercomplex.

Falke D, Biefel B, Haase A, Franke S, Fischer M, Sawers RG.

J Bacteriol. 2019 May 8;201(11). pii: e00104-19. doi: 10.1128/JB.00104-19. Print 2019 Jun 1.

PMID:
30858301
3.

Cytochrome bd Oxidase Has an Important Role in Sustaining Growth and Development of Streptomyces coelicolor A3(2) under Oxygen-Limiting Conditions.

Fischer M, Falke D, Naujoks C, Sawers RG.

J Bacteriol. 2018 Jul 25;200(16). pii: e00239-18. doi: 10.1128/JB.00239-18. Print 2018 Aug 15.

4.

The C-terminal Six Amino Acids of the FNT Channel FocA Are Required for Formate Translocation But Not Homopentamer Integrity.

Hunger D, Röcker M, Falke D, Lilie H, Sawers RG.

Front Microbiol. 2017 Aug 22;8:1616. doi: 10.3389/fmicb.2017.01616. eCollection 2017.

5.

EuPathDB: the eukaryotic pathogen genomics database resource.

Aurrecoechea C, Barreto A, Basenko EY, Brestelli J, Brunk BP, Cade S, Crouch K, Doherty R, Falke D, Fischer S, Gajria B, Harb OS, Heiges M, Hertz-Fowler C, Hu S, Iodice J, Kissinger JC, Lawrence C, Li W, Pinney DF, Pulman JA, Roos DS, Shanmugasundram A, Silva-Franco F, Steinbiss S, Stoeckert CJ Jr, Spruill D, Wang H, Warrenfeltz S, Zheng J.

Nucleic Acids Res. 2017 Jan 4;45(D1):D581-D591. doi: 10.1093/nar/gkw1105. Epub 2016 Nov 29.

6.

Phosphate and oxygen limitation induce respiratory nitrate reductase 3 synthesis in stationary-phase mycelium of Streptomyces coelicolor A3(2).

Falke D, Fischer M, Sawers RG.

Microbiology. 2016 Sep;162(9):1689-1697. doi: 10.1099/mic.0.000349. Epub 2016 Aug 5.

PMID:
27499000
7.

Oxygen and Nitrate Respiration in Streptomyces coelicolor A3(2).

Sawers RG, Falke D, Fischer M.

Adv Microb Physiol. 2016;68:1-40. doi: 10.1016/bs.ampbs.2016.02.004. Epub 2016 Mar 10. Review.

PMID:
27134020
8.

The glycyl-radical enzyme 2-ketobutyrate formate-lyase, TdcE, interacts specifically with the formate-translocating FNT-channel protein FocA.

Falke D, Doberenz C, Hunger D, Sawers RG.

Biochem Biophys Rep. 2016 Apr 16;6:185-189. doi: 10.1016/j.bbrep.2016.04.005. eCollection 2016 Jul.

9.

Tolerability, Safety, and Quality of Life with Tapentadol Prolonged Release (PR) Compared with Oxycodone/Naloxone PR in Patients with Severe Chronic Low Back Pain with a Neuropathic Component: A Randomized, Controlled, Open-label, Phase 3b/4 Trial.

Baron R, Jansen JP, Binder A, Pombo-Suarez M, Kennes L, Müller M, Falke D, Steigerwald I.

Pain Pract. 2016 Jun;16(5):600-19. doi: 10.1111/papr.12361. Epub 2015 Nov 11.

PMID:
26554630
10.

Effectiveness of Tapentadol Prolonged Release (PR) Compared with Oxycodone/Naloxone PR for the Management of Severe Chronic Low Back Pain with a Neuropathic Component: A Randomized, Controlled, Open-Label, Phase 3b/4 Study.

Baron R, Likar R, Martin-Mola E, Blanco FJ, Kennes L, Müller M, Falke D, Steigerwald I.

Pain Pract. 2016 Jun;16(5):580-99. doi: 10.1111/papr.12308. Epub 2015 Jun 12.

PMID:
26095455
11.

Oxygen-dependent control of respiratory nitrate reduction in mycelium of Streptomyces coelicolor A3(2).

Fischer M, Falke D, Pawlik T, Sawers RG.

J Bacteriol. 2014 Dec;196(23):4152-62. doi: 10.1128/JB.02202-14. Epub 2014 Sep 15.

12.

Pyruvate formate-lyase interacts directly with the formate channel FocA to regulate formate translocation.

Doberenz C, Zorn M, Falke D, Nannemann D, Hunger D, Beyer L, Ihling CH, Meiler J, Sinz A, Sawers RG.

J Mol Biol. 2014 Jul 29;426(15):2827-39. doi: 10.1016/j.jmb.2014.05.023. Epub 2014 Jun 2.

13.
14.
15.

Effectiveness and tolerability of tapentadol prolonged release compared with prior opioid therapy for the management of severe, chronic osteoarthritis pain.

Steigerwald I, Schenk M, Lahne U, Gebuhr P, Falke D, Hoggart B.

Clin Drug Investig. 2013 Sep;33(9):607-19. doi: 10.1007/s40261-013-0102-0.

16.

A respiratory nitrate reductase active exclusively in resting spores of the obligate aerobe Streptomyces coelicolor A3(2).

Fischer M, Falke D, Sawers RG.

Mol Microbiol. 2013 Sep;89(6):1259-73. doi: 10.1111/mmi.12344. Epub 2013 Aug 14.

17.

Tapentadol prolonged release versus strong opioids for severe, chronic low back pain: results of an open-label, phase 3b study.

Gálvez R, Schäfer M, Hans G, Falke D, Steigerwald I.

Adv Ther. 2013 Mar;30(3):229-59. doi: 10.1007/s12325-013-0015-6. Epub 2013 Mar 7.

PMID:
23475406
18.

Coordination of FocA and pyruvate formate-lyase synthesis in Escherichia coli demonstrates preferential translocation of formate over other mixed-acid fermentation products.

Beyer L, Doberenz C, Falke D, Hunger D, Suppmann B, Sawers RG.

J Bacteriol. 2013 Apr;195(7):1428-35. doi: 10.1128/JB.02166-12. Epub 2013 Jan 18.

19.

Terminal reduction reactions of nitrate and sulfate assimilation in Streptomyces coelicolor A3(2): identification of genes encoding nitrite and sulfite reductases.

Fischer M, Schmidt C, Falke D, Sawers RG.

Res Microbiol. 2012 Jun;163(5):340-8. doi: 10.1016/j.resmic.2012.05.004. Epub 2012 Jun 1.

PMID:
22659143
20.

Unexpected oligomeric structure of the FocA formate channel of Escherichia coli : a paradigm for the formate-nitrite transporter family of integral membrane proteins.

Falke D, Schulz K, Doberenz C, Beyer L, Lilie H, Thiemer B, Sawers RG.

FEMS Microbiol Lett. 2010 Feb;303(1):69-75. doi: 10.1111/j.1574-6968.2009.01862.x. Epub 2009 Nov 23.

21.

Selective transcription of p53 target genes by zinc finger-p53 DNA binding domain chimeras.

Falke D, Fisher MH, Juliano RL.

Biochim Biophys Acta. 2004 Nov 24;1681(1):15-27.

PMID:
15566940
22.

Macromolecular therapeutics: emerging strategies for drug discovery in the postgenome era.

Juliano RL, Astriab-Fisher A, Falke D.

Mol Interv. 2001 Apr;1(1):40-53. Review.

PMID:
14993337
23.

P53-dependent cell-killing by selective repression of thymidine kinase and reduced prodrug activation.

Xu D, Falke D, Juliano RL.

Mol Pharmacol. 2003 Aug;64(2):289-97.

PMID:
12869633
24.

Selective gene regulation with designed transcription factors: implications for therapy.

Falke D, Juliano RL.

Curr Opin Mol Ther. 2003 Apr;5(2):161-6. Review.

PMID:
12772506
25.

Cloning and expression of the complement receptor glycoprotein C from Herpesvirus simiae (herpes B virus): protection from complement-mediated cell lysis.

Huemer HP, Wechselberger C, Bennett AM, Falke D, Harrington L.

J Gen Virol. 2003 May;84(Pt 5):1091-100.

PMID:
12692273
26.

Design of artificial transcription factors to selectively regulate the pro-apoptotic bax gene.

Falke D, Fisher M, Ye D, Juliano RL.

Nucleic Acids Res. 2003 Feb 1;31(3):e10.

27.

Nitrogen metabolism in Streptomyces coelicolor A3(2): modification of glutamine synthetase I by an adenylyltransferase.

Fink D, Falke D, Wohlleben W, Engels A.

Microbiology. 1999 Sep;145 ( Pt 9):2313-22.

PMID:
10517584
28.

The human autoantigen La/SS-B accelerates herpes simplex virus type 1 replication in transfected mouse 3T3 cells.

Bachmann M, Deister H, Pautz A, Laubinger J, Schmitz M, Falke D, Podlech J, Grölz D.

Clin Exp Immunol. 1998 Jun;112(3):482-9.

29.

Herpes simplex virus and the cytoskeleton.

Falke D.

Trends Microbiol. 1997 Aug;5(8):306. No abstract available.

PMID:
9263407
30.

Localization of latency-associated transcripts in the uterovaginal plexus of herpes simplex virus type 1 and 2 latently infected mice.

Podlech J, Hengerer F, Fleck M, Kunkel J, Falke D.

J Gen Virol. 1997 May;78 ( Pt 5):1103-8.

PMID:
9152429
32.
33.

TNF-alpha mediated apoptosis of CD4 positive T-lymphocytes. A model of T-cell depletion in HIV infected individuals.

Klein SA, Dobmeyer JM, Dobmeyer TS, Falke D, Kabelitz D, Friese K, Helm EB, Hoelzer D, Rossol-Voth R.

Eur J Med Res. 1996 Feb 22;1(5):249-58.

PMID:
9374446
35.

Replication of herpes simplex virus type 1 and 2 in the medulla of the adrenal gland after vaginal infection of mice.

Podlech J, Hengerer F, Fleck M, Walev I, Falke D.

Arch Virol. 1996;141(10):1999-2008.

PMID:
8920831
36.
38.
43.

Herpes simplex virus hepatitis and related problems.

Dienes HP, Schirmacher P, Weise K, Falke D.

Int Rev Exp Pathol. 1994;35:1-38. Review. No abstract available.

PMID:
7860188
44.

[Milestones in virology].

Falke D.

Immun Infekt. 1993 Jun;21(3):69-74. Review. German.

PMID:
7687580
45.
46.

Vaginal infection of mice with HSV type 2 variant ER-: a new animal model for human primary genital HSV type 2 infections.

Wollert KC, Fleck M, Podlech J, Weise K, Corell A, Falke D.

J Virol Methods. 1992 Mar;36(3):265-76.

PMID:
1313825
47.

Translocation of the nuclear autoantigen La to the cell surface of herpes simplex virus type 1 infected cells.

Bachmann M, Althoff H, Tröster H, Selenka C, Falke D, Müller WE.

Autoimmunity. 1992;12(1):37-45.

PMID:
1617103
48.

Factors influencing the interaction of herpes simplex virus glycoprotein C with the third component of complement.

Huemer HP, Larcher C, Dierich MP, Falke D.

Arch Virol. 1992;127(1-4):291-303.

PMID:
1333754
49.
50.

Axonal-transsynaptic spread as the basic pathogenetic mechanism in B virus infection of the nervous system.

Gosztonyi G, Falke D, Ludwig H.

J Med Primatol. 1992 Jan;21(1):42-3.

PMID:
1318382

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