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Items: 1 to 50 of 229

1.

EGFR, but not COX-2, protein in resected pancreatic ductal adenocarcinoma is associated with poor survival.

Fagman JB, Ljungman D, Falk P, Iresjö BM, Engström C, Naredi P, Lundholm K.

Oncol Lett. 2019 Jun;17(6):5361-5368. doi: 10.3892/ol.2019.10224. Epub 2019 Apr 5.

2.

Band adhesions not related to previous abdominal surgery - A retrospective cohort analysis of risk factors.

Skoglar A, Gunnarsson U, Falk P.

Ann Med Surg (Lond). 2018 Nov 13;36:185-190. doi: 10.1016/j.amsu.2018.11.007. eCollection 2018 Dec.

3.

Discovery of the Novel Entecavir-Resistant Hepatitis B Virus Reverse Transcriptase A181C Substitution From an Integrated Genotypic Analysis.

Rose RE, Hernandez D, Falk PJ, Ericson K, Zhou N, Thiry A, McPhee F.

Hepatol Commun. 2018 Aug 21;2(9):1123-1135. doi: 10.1002/hep4.1231. eCollection 2018 Sep.

4.

Evaluating full-thickness skin grafts in intraperitoneal onlay mesh position versus onlay position in mice.

Winsnes A, Gunnarsson U, Falk P, Stark B, Moskaug JØ, Strigård K.

J Surg Res. 2018 Oct;230:155-163. doi: 10.1016/j.jss.2018.04.041. Epub 2018 May 31.

5.

P3-P4 ureas and reverse carbamates as potent HCV NS3 protease inhibitors: Effective transposition of the P4 hydrogen bond donor.

Venables BL, Sin N, Wang AX, Sun LQ, Tu Y, Hernandez D, Sheaffer A, Lee M, Dunaj C, Zhai G, Barry D, Friborg J, Yu F, Knipe J, Sandquist J, Falk P, Parker D, Good AC, Rajamani R, McPhee F, Meanwell NA, Scola PM.

Bioorg Med Chem Lett. 2018 Jun 1;28(10):1853-1859. doi: 10.1016/j.bmcl.2018.04.009. Epub 2018 Apr 5.

PMID:
29650290
6.

Role of matrix metalloproteinases in tumour invasion: immunohistochemistry of peritoneum from peritoneal carcinomatosis.

Falk P, Jonsson A, Swartling T, Asplund D, Ivarsson ML.

Med Oncol. 2018 Apr 5;35(5):64. doi: 10.1007/s12032-018-1122-7.

7.

Stability of matrix metalloproteinase-9 as biological marker in colorectal cancer.

Jonsson A, Hjalmarsson C, Falk P, Ivarsson ML.

Med Oncol. 2018 Mar 9;35(4):50. doi: 10.1007/s12032-018-1109-4.

8.

Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond Donor.

Zheng B, D'Andrea SV, Sun LQ, Wang AX, Chen Y, Hrnciar P, Friborg J, Falk P, Hernandez D, Yu F, Sheaffer AK, Knipe JO, Mosure K, Rajamani R, Good AC, Kish K, Tredup J, Klei HE, Paruchuri M, Ng A, Gao Q, Rampulla RA, Mathur A, Meanwell NA, McPhee F, Scola PM.

ACS Med Chem Lett. 2018 Jan 19;9(2):143-148. doi: 10.1021/acsmedchemlett.7b00503. eCollection 2018 Feb 8.

9.

An ex vivo model using human peritoneum to explore mesh-tissue integration.

Falk P, Ruiz-Jasbon F, Strigård K, Gunnarsson U, Ivarsson ML.

Biol Open. 2017 Sep 15;6(9):1391-1395. doi: 10.1242/bio.024992.

10.

Colorectal Cancer Cells Adhere to Traumatized Peritoneal Tissue in Clusters, An Experimental Study.

Falk P, Jonsson A, Swartling T, Ivarsson ML.

J Invest Surg. 2018 Aug;31(4):349-356. doi: 10.1080/08941939.2017.1326544. Epub 2017 May 25.

PMID:
28541718
11.

DNA alterations in Cd133+ and Cd133- tumour cells enriched from intra-operative human colon tumour biopsies.

Cervantes-Madrid D, Wettergren Y, Falk P, Lundholm K, Asting AG.

BMC Cancer. 2017 Mar 27;17(1):219. doi: 10.1186/s12885-017-3206-8.

12.

Discovery of a Potent Acyclic, Tripeptidic, Acyl Sulfonamide Inhibitor of Hepatitis C Virus NS3 Protease as a Back-up to Asunaprevir with the Potential for Once-Daily Dosing.

Sun LQ, Mull E, Zheng B, D'Andrea S, Zhao Q, Wang AX, Sin N, Venables BL, Sit SY, Chen Y, Chen J, Cocuzza A, Bilder DM, Mathur A, Rampulla R, Chen BC, Palani T, Ganesan S, Arunachalam PN, Falk P, Levine S, Chen C, Friborg J, Yu F, Hernandez D, Sheaffer AK, Knipe JO, Han YH, Schartman R, Donoso M, Mosure K, Sinz MW, Zvyaga T, Rajamani R, Kish K, Tredup J, Klei HE, Gao Q, Ng A, Mueller L, Grasela DM, Adams S, Loy J, Levesque PC, Sun H, Shi H, Sun L, Warner W, Li D, Zhu J, Wang YK, Fang H, Cockett MI, Meanwell NA, McPhee F, Scola PM.

J Med Chem. 2016 Sep 8;59(17):8042-60. doi: 10.1021/acs.jmedchem.6b00821. Epub 2016 Aug 26.

PMID:
27564532
13.

Giant ventral hernia-relationship between abdominal wall muscle strength and hernia area.

Strigård K, Clay L, Stark B, Gunnarsson U, Falk P.

BMC Surg. 2016 Aug 2;16(1):50. doi: 10.1186/s12893-016-0166-x.

14.

Levels of matrix metalloproteinases differ in plasma and serum - aspects regarding analysis of biological markers in cancer.

Jonsson A, Hjalmarsson C, Falk P, Ivarsson ML.

Br J Cancer. 2016 Sep 6;115(6):703-6. doi: 10.1038/bjc.2016.127. Epub 2016 May 17.

15.

In Vitro Assessment of Re-treatment Options for Patients with Hepatitis C Virus Genotype 1b Infection Resistant to Daclatasvir Plus Asunaprevir.

Friborg J, Zhou N, Han Z, Yang X, Falk P, Mendez P, McPhee F.

Infect Dis Ther. 2014 Dec 17. [Epub ahead of print]

16.

Thymidine phosphorylase expression is associated with time to progression in patients with metastatic colorectal cancer.

Lindskog EB, Derwinger K, Gustavsson B, Falk P, Wettergren Y.

BMC Clin Pathol. 2014 Jun 10;14:25. doi: 10.1186/1472-6890-14-25. eCollection 2014.

17.

Stress response and well-being after open, laparoscopic, and NOTES transgastric uterine horn resection in a randomized porcine model.

Bergström M, Azadani A, Falk P, Park PO.

Surg Endosc. 2014 Aug;28(8):2421-7. doi: 10.1007/s00464-014-3491-0. Epub 2014 Mar 12.

PMID:
24619329
18.

The discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection.

Scola PM, Sun LQ, Wang AX, Chen J, Sin N, Venables BL, Sit SY, Chen Y, Cocuzza A, Bilder DM, D'Andrea SV, Zheng B, Hewawasam P, Tu Y, Friborg J, Falk P, Hernandez D, Levine S, Chen C, Yu F, Sheaffer AK, Zhai G, Barry D, Knipe JO, Han YH, Schartman R, Donoso M, Mosure K, Sinz MW, Zvyaga T, Good AC, Rajamani R, Kish K, Tredup J, Klei HE, Gao Q, Mueller L, Colonno RJ, Grasela DM, Adams SP, Loy J, Levesque PC, Sun H, Shi H, Sun L, Warner W, Li D, Zhu J, Meanwell NA, McPhee F.

J Med Chem. 2014 Mar 13;57(5):1730-52. doi: 10.1021/jm500297k. Epub 2014 Mar 5.

PMID:
24564672
19.

Discovery and early clinical evaluation of BMS-605339, a potent and orally efficacious tripeptidic acylsulfonamide NS3 protease inhibitor for the treatment of hepatitis C virus infection.

Scola PM, Wang AX, Good AC, Sun LQ, Combrink KD, Campbell JA, Chen J, Tu Y, Sin N, Venables BL, Sit SY, Chen Y, Cocuzza A, Bilder DM, D'Andrea S, Zheng B, Hewawasam P, Ding M, Thuring J, Li J, Hernandez D, Yu F, Falk P, Zhai G, Sheaffer AK, Chen C, Lee MS, Barry D, Knipe JO, Li W, Han YH, Jenkins S, Gesenberg C, Gao Q, Sinz MW, Santone KS, Zvyaga T, Rajamani R, Klei HE, Colonno RJ, Grasela DM, Hughes E, Chien C, Adams S, Levesque PC, Li D, Zhu J, Meanwell NA, McPhee F.

J Med Chem. 2014 Mar 13;57(5):1708-29. doi: 10.1021/jm401840s. Epub 2014 Feb 20.

PMID:
24555570
20.

TGF-β1 promotes transition of mesothelial cells into fibroblast phenotype in response to peritoneal injury in a cell culture model.

Falk P, Angenete E, Bergström M, Ivarsson ML.

Int J Surg. 2013;11(9):977-82. doi: 10.1016/j.ijsu.2013.06.005. Epub 2013 Jun 21.

21.

Resistance analysis of hepatitis C virus genotype 1 prior treatment null responders receiving daclatasvir and asunaprevir.

McPhee F, Hernandez D, Yu F, Ueland J, Monikowski A, Carifa A, Falk P, Wang C, Fridell R, Eley T, Zhou N, Gardiner D.

Hepatology. 2013 Sep;58(3):902-11. doi: 10.1002/hep.26388. Epub 2013 Jul 16.

PMID:
23504694
22.

Intestinal mucosal MMP-1 - a prognostic factor in colon cancer.

Langenskiöld M, Ivarsson ML, Holmdahl L, Falk P, Kåbjörn-Gustafsson C, Angenete E.

Scand J Gastroenterol. 2013 May;48(5):563-9. doi: 10.3109/00365521.2012.708939. Epub 2013 Mar 14.

PMID:
23485198
23.

Establishment of a robust hepatitis C virus replicon cell line over-expressing P-glycoprotein that facilitates analysis of P-gp drug transporter effects on inhibitor antiviral activity.

Hernandez D, Falk P, Yu F, Zhai G, Quan Y, Faria T, Cao K, Scola P, McPhee F.

Biochem Pharmacol. 2013 Jan 1;85(1):21-8. doi: 10.1016/j.bcp.2012.10.002. Epub 2012 Oct 11.

PMID:
23063413
24.

Effect of a DACC dressing on the growth properties and proliferation rate of cultured fibroblasts.

Falk P, Ivarsson ML.

J Wound Care. 2012 Jul;21(7):327-8, 330-2.

PMID:
22886332
25.

Preclinical Profile and Characterization of the Hepatitis C Virus NS3 Protease Inhibitor Asunaprevir (BMS-650032).

McPhee F, Sheaffer AK, Friborg J, Hernandez D, Falk P, Zhai G, Levine S, Chaniewski S, Yu F, Barry D, Chen C, Lee MS, Mosure K, Sun LQ, Sinz M, Meanwell NA, Colonno RJ, Knipe J, Scola P.

Antimicrob Agents Chemother. 2012 Oct;56(10):5387-96. doi: 10.1128/AAC.01186-12. Epub 2012 Aug 6.

26.

Evaluation of effects on the peritoneum after intraperitoneal α-radioimmunotherapy with (211)At.

Cederkrantz E, Angenete E, Bäck T, Falk P, Haraldsson B, Ivarsson ML, Jensen H, Lindegren S, Hultborn R, Jacobsson L.

Cancer Biother Radiopharm. 2012 Aug;27(6):353-64. doi: 10.1089/cbr.2012.1184. Epub 2012 Jun 12.

PMID:
22690847
27.

Local and systemic expressions of MMP-9, TIMP-1 and PAI-1 in patients undergoing surgery for clinically suspected appendicitis.

Solberg A, Holmdahl L, Falk P, Wolving M, Palmgren I, Ivarsson ML.

Eur Surg Res. 2012;48(2):99-105. doi: 10.1159/000337031. Epub 2012 Apr 20.

PMID:
22516898
28.

Resistance analysis of the hepatitis C virus NS3 protease inhibitor asunaprevir.

McPhee F, Friborg J, Levine S, Chen C, Falk P, Yu F, Hernandez D, Lee MS, Chaniewski S, Sheaffer AK, Pasquinelli C.

Antimicrob Agents Chemother. 2012 Jul;56(7):3670-81. doi: 10.1128/AAC.00308-12. Epub 2012 Apr 16.

29.

Development of a chimeric replicon system for phenotypic analysis of NS3 protease sequences from HCV clinical isolates.

Sheaffer AK, Lee MS, Hernandez D, Chaniewski S, Yu F, Falk P, Friborg J, Zhai G, McPhee F.

Antivir Ther. 2011;16(5):705-18. doi: 10.3851/IMP1825.

PMID:
21817192
30.

Decreased peritoneal expression of active transforming growth factor ß1 during laparoscopic cholecystectomy with heated carbon dioxide.

Lensvelt MM, Ivarsson ML, Brokelman WJ, Falk P, Reijnen MM.

Arch Surg. 2010 Oct;145(10):968-72. doi: 10.1001/archsurg.2010.219.

PMID:
20956765
31.

Trimethoprim-sulfamethoxazole-induced aseptic meningitis.

Repplinger MD, Falk PM.

Am J Emerg Med. 2011 Feb;29(2):242.e3-5. doi: 10.1016/j.ajem.2010.03.006. Epub 2010 May 4. No abstract available.

PMID:
20825900
32.

Peritoneal transforming growth factor beta-1 expression during prolonged laparoscopic procedures.

Lensvelt MM, Brokelman WJ, Ivarsson ML, Falk P, Reijnen MM.

J Laparoendosc Adv Surg Tech A. 2010 Jul-Aug;20(6):545-50. doi: 10.1089/lap.2009.0464.

PMID:
20578923
33.

Tissue proteolysis in appendicitis with perforation.

Solberg A, Holmdahl L, Falk P, Willén R, Palmgren I, Ivarsson ML.

J Surg Res. 2011 Aug;169(2):194-201. doi: 10.1016/j.jss.2010.01.013. Epub 2010 Feb 4.

PMID:
20338595
34.

Epidemiology of methicillin-susceptible Staphylococcus aureus in a university medical center day care facility.

Hewlett AL, Falk PS, Hughes KS, Mayhall CG.

Pediatr Infect Dis J. 2010 Feb;29(2):145-7.

PMID:
20135830
35.

Preoperative radiotherapy and extracellular matrix remodeling in rectal mucosa and tumour matrix metalloproteinases and plasminogen components.

Angenete E, Oresland T, Falk P, Breimer M, Hultborn R, Ivarsson ML.

Acta Oncol. 2009;48(8):1144-51. doi: 10.3109/02841860903150510.

PMID:
19863222
36.

Differential prognostic impact of uPA and PAI-1 in colon and rectal cancer.

Langenskiöld M, Holmdahl L, Angenete E, Falk P, Nordgren S, Ivarsson ML.

Tumour Biol. 2009;30(4):210-20. doi: 10.1159/000239796. Epub 2009 Sep 21.

PMID:
19776673
37.

Epidemiology of methicillin-resistant Staphylococcus aureus in a university medical center day care facility.

Hewlett AL, Falk PS, Hughes KS, Mayhall CG.

Infect Control Hosp Epidemiol. 2009 Oct;30(10):985-92. doi: 10.1086/605721.

PMID:
19743900
38.

The peritoneal fibrinolytic response to conventional and laparoscopic colonic surgery.

Brokelman W, Holmdahl L, Falk P, Klinkenbijl J, Reijnen M.

J Laparoendosc Adv Surg Tech A. 2009 Aug;19(4):489-93. doi: 10.1089/lap.2008.0088.

PMID:
19670975
39.

Progress of tissue injury in appendicitis involves the serine proteases uPA and PAI-1.

Solberg A, Holmdahl L, Falk P, Willén R, Palmgren I, Ivarsson ML.

Scand J Gastroenterol. 2009;44(5):579-84. doi: 10.1080/00365520802699286.

PMID:
19153874
40.

Studies of TGF-beta(1-3) in serosal fluid during abdominal surgery and their effect on in vitro human mesothelial cell proliferation.

Falk P, Bergström M, Palmgren I, Holmdahl L, Breimer ME, Ivarsson ML.

J Surg Res. 2009 Jun 15;154(2):312-6. doi: 10.1016/j.jss.2008.05.012. Epub 2008 Jun 20.

PMID:
19062040
41.

High-dose therapy with hematopoietic stem cell rescue in patients with poor prognosis Ewing family tumors.

Rosenthal J, Bolotin E, Shakhnovits M, Pawlowska A, Falk P, Qian D, Oliver C, Sato J, Miser J, Forman S.

Bone Marrow Transplant. 2008 Sep;42(5):311-8. doi: 10.1038/bmt.2008.169. Epub 2008 Jun 30.

PMID:
18587438
42.

Decreased peritoneal tissue plasminogen activator during prolonged laparoscopic surgery.

Brokelman WJ, Holmdahl L, Janssen IM, Falk P, Bergström M, Klinkenbijl JH, Reijnen MM.

J Surg Res. 2009 Jan;151(1):89-93. doi: 10.1016/j.jss.2008.01.005. Epub 2008 Feb 1.

PMID:
18541262
43.

uPA and PAI-1 in rectal cancer--relationship to radiotherapy and clinical outcome.

Angenete E, Langenskiöld M, Palmgren I, Falk P, Oresland T, Ivarsson ML.

J Surg Res. 2009 May 1;153(1):46-53. doi: 10.1016/j.jss.2008.02.043. Epub 2008 Apr 7.

PMID:
18533186
44.

A local imbalance between MMP and TIMP may have an implication on the severity and course of appendicitis.

Solberg A, Holmdahl L, Falk P, Palmgren I, Ivarsson ML.

Int J Colorectal Dis. 2008 Jun;23(6):611-8. doi: 10.1007/s00384-008-0452-x. Epub 2008 Mar 18.

PMID:
18347803
45.

Broadband light generation at approximately 1300 nm through spectrally recoiled solitons and dispersive waves.

Falk P, Frosz MH, Bang O, Thrane L, Andersen PE, Bjarklev AO, Hansen KP, Broeng J.

Opt Lett. 2008 Mar 15;33(6):621-3.

PMID:
18347730
46.

Increased TGF-beta 1 protein expression in patients with advanced colorectal cancer.

Langenskiöld M, Holmdahl L, Falk P, Angenete E, Ivarsson ML.

J Surg Oncol. 2008 Apr 1;97(5):409-15. doi: 10.1002/jso.20961.

PMID:
18176914
47.

Phase II trial of a transplantation regimen of yttrium-90 ibritumomab tiuxetan and high-dose chemotherapy in patients with non-Hodgkin's lymphoma.

Krishnan A, Nademanee A, Fung HC, Raubitschek AA, Molina A, Yamauchi D, Rodriguez R, Spielberger RT, Falk P, Palmer JM, Forman SJ.

J Clin Oncol. 2008 Jan 1;26(1):90-5. Epub 2007 Nov 19.

PMID:
18025438
48.

Heating of carbon dioxide during insufflation alters the peritoneal fibrinolytic response to laparoscopic surgery : A clinical trial.

Brokelman WJ, Holmdahl L, Bergström M, Falk P, Klinkenbijl JH, Reijnen MM.

Surg Endosc. 2008 May;22(5):1232-6. Epub 2007 Oct 18.

PMID:
17943363
49.

Peripheral blood hematopoietic stem cell mobilization and collection efficacy is not an independent prognostic factor for autologous stem cell transplantation.

Wang S, Nademanee A, Qian D, Dagis A, Park HS, Fridey J, Smith E, Snyder D, Somlo G, Stein A, Rosenthal J, Falk P, Kogut N, Palmer J, Gaal K, Kim Y, Bhatia R, Yuan S, Kay C, Weiss L, Forman S.

Transfusion. 2007 Dec;47(12):2207-16. Epub 2007 Aug 21.

PMID:
17714420
50.

Transforming growth factor beta-1 in rectal tumour, mucosa and plasma in relation to radiotherapy and clinical outcome in rectal cancer patients.

Angenete E, Langenskiöld M, Palmgren I, Falk P, Oresland T, Ivarsson ML.

Int J Colorectal Dis. 2007 Nov;22(11):1331-8. Epub 2007 Jul 27.

PMID:
17657504

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